Ochotona princeps (American pika): 101529313
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Entry
101529313 CDS
T07609
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00230
Purine metabolism
opi01100
Metabolic pathways
opi04022
cGMP-PKG signaling pathway
opi04024
cAMP signaling pathway
opi04924
Renin secretion
opi05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101529313 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
101529313 (PDE3A)
04022 cGMP-PKG signaling pathway
101529313 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
101529313 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101529313 (PDE3A)
Enzymes [BR:
opi01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
101529313 (PDE3A)
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Gene cluster
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Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
101529313
NCBI-ProteinID:
XP_012784530
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Position
8A:complement(13162765..13412621)
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AA seq
1137 aa
AA seq
DB search
MDTPGSSRASQAPAAARDCYRGRAGSGCQGGCWGTLVLRPLLRRSRKLSSALCAGSLSFL
LALLVRLVRGEQGCDLEQRKEAVAAAQEEEEEEAARAAEGGVFPSPRGGAPGGGAPFSPW
LQPSALLLILLCAFFWMGLYLLRAGVRLPLAVALLAACCGGEALVQLGLGVGEDHLLSLP
AAGVVLSCLAAATWLVLRLKLGVPMIALTSAVRTVSLTSLERFKVAWRPYLAYLAGVLGI
LLARCVEQLLPQSAGAAPRERLGSRLLVGTKEDIPGLKRRRRSSSVVAAEMSSGGSKSHR
RTSLPCIPRDQLMGHSEWDHRRGLRGPQSSGTSITVDIAVMGEAHGLITDLLADPSLPPN
VCTSLRAVSNLLSTQLTFQAVHKPRVNPAVSFSENYTCSDSEESSEKDKLAIAKRLRRSL
PPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPSVSAVTPDSWNSPAMMT
LTKSRSFTSSYAVSAANHVKVKKQNRPGDLSTISPLSSPCSSPLQGTPASSPISKVSTVQ
FPEPADTPARQGPGSHKPLTCTQSAPDLSPQSLATPVICSSCGRPYSQGIPADGPLDRSG
PAPRMPSRADDTAQVTSDYETNNNSDSSDIVQNEDETECPSQPLRNVSACSTYAPETLMF
VDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVENIGRKCGRILSQVSYRLFEDMGLFE
AFKIPVREFMNYFHALEIGYRDIPYHNRVHATDVLHAVWYLTTQPIPGLSTVVSDHGSAS
DSDSDSGFTHGHMGYVFSKMYTVPDDRYGCLSGNIPALELMALYVAAAMHDYDHPGRTNA
FLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAIL
ATDLKKHFDFVAKFNAKVNDEVGIDWTNENDRLLVCQMCIKLADINGPAKCKELHLQWTE
GIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCHSYDSAGLMPGKW
VEDSDESGDTDDPEEEEEGEEEADAPNEEETCENESPRKKAFKRRKIYCQITQHLLQNHK
MWKKVIEDEQRLAGIENQSVEQTLPQPSSEKIQAIEEEEEEKGKPRAEEIPAPQPNQ
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atggacacacccggttccagcagggcgagccaggcccccgcggcggcgcgggactgctac
cgtggtcgcgcaggctccggctgccaaggcggctgctggggcaccctggtgctgcggcca
ctcctccggcgctcgcggaaactttcctcagcgctgtgcgcgggctccctgtcgtttctg
ctggcgctgctggtgaggctggtccgcggggagcagggctgtgacttggagcagaggaag
gaggcggtggcggcggcgcaggaggaggaggaggaggaagcggcccgggctgcagaaggg
ggcgtcttccccagccctcggggaggcgctcccgggggcggcgcgccgttcagcccctgg
ctgcagccctcggcgctgctgctcattctgctgtgtgccttcttctggatgggcttgtac
ctcctgcgcgccggggtgcgcctgcctctggccgtcgcgctgctggccgcctgctgcggg
ggggaagcgctcgtgcagctcggactgggcgtcggggaggatcacttgctctcgttgccg
gccgccggcgtggtgctcagctgcctggccgcggcgacatggctggtgctgaggctgaag
ctgggcgtccccatgatcgccttgactagcgcggtcaggaccgtgtccctcacttcctta
gagaggtttaaggtcgcttggagaccatacctggcgtacttggccggcgtgctggggatt
cttctggccaggtgtgtggagcagctcttgccgcagtcggcgggggctgcaccgagggag
cgtttggggtcccggctgcttgttgggaccaaggaagacatcccgggtttgaagaggagg
aggcggtccagctccgtggtggcagccgagatgtccagcggcggcagcaagtcccaccgg
aggacctccctgccctgtataccgcgggatcagctcatgggacattcggaatgggaccac
agacgaggactaagggggccccagtcttcaggaaccagtatcactgtggatattgctgtg
atgggcgaggcccacggcctcattactgacctcctggcagacccctctctgccgccgaac
gtatgcacgtccttgagggccgtgagcaaccttctcagcacacagctcaccttccaggcc
gttcacaagcccagagtgaatccagcagtttccttcagtgaaaactatacttgttctgac
tccgaagagagctccgagaaagacaagctggctattgccaagcgcctgagaaggagtttg
ccccctggcttgttgagacgagtttcatcaacttggacaactaccacctctgcaacaggt
ctacccaccttggagcctgcaccagtaaggagggaccgtagtgccagcatcaaactgcat
gaagcaccttcagtcagtgccgttactcctgactcttggaacagcccagcgatgatgacc
ctcaccaaaagcaggtcctttacgtcatcgtatgctgtgtcggcagcaaaccacgtgaag
gtgaagaagcagaatcgaccaggtgacttaagtacaatttcacctctctcctccccttgc
tcctcacctctccaagggactcctgccagcagccccatcagcaaagtttctacagtgcag
tttccagaacctgctgacacacctgcccgacaaggcccgggttcccacaagcccttaacg
tgcacgcagagtgcccccgacctttctccgcagagtctggctacacctgtgatatgtagc
agctgtggccgaccttattcccagggaattcctgctgacgggcccctggacagaagtggc
ccagcccctcggatgccgagcagagcagatgacactgctcaagttacctctgattacgaa
accaacaacaacagcgacagcagtgacattgtccagaatgaagatgagactgagtgcccc
agccagccactgaggaacgtgtctgcctgcagcacctacgctcctgagaccttgatgttc
gtggataagccaattcttgctcctgaacctcttgtcatggataacctggactcaatcatg
gagcaactaaatacttggaattttccaatttttgatttagtggaaaacattggaagaaaa
tgcggtcgtattcttagtcaggtgtcctacagactttttgaagacatgggcctctttgaa
gcctttaaaattcctgttcgggaatttatgaattattttcatgctttggagattggatat
agggatattccttatcacaatagagttcacgccactgacgtcttgcatgctgtttggtat
cttacaacgcagcccattccgggcctctccactgtcgtcagcgaccatggatcagcaagt
gactcagattctgacagtggattcacgcatggacatatgggatatgtattctcaaaaatg
tatactgtgcctgatgacagatacggctgcctctctgggaatatccctgccttggaactg
atggctctgtatgtggctgcagccatgcatgactatgaccacccgggaagaacgaacgcc
ttcctggtcgccaccagtgcgcctcaggcagtgctatataacgatcgctcggttttggaa
aatcatcatgcagctgctgcgtggaatcttttcatgtcgcggccagaatacaacttctta
gttaaccttgaccacgtggaatttaagcacttccgtttcctcgtcatcgaagcaatactg
gcaactgacctgaagaaacactttgacttcgtagccaagtttaacgccaaggtaaatgat
gaagttggaatagattggaccaatgaaaacgatcgcctactggtttgtcagatgtgtata
aagttggcagatattaacggaccagcgaaatgtaaagaattgcaccttcagtggacagaa
ggcattgttaatgaattttatgaacagggtgatgaagaggccagccttggtctgcccatt
agccccttcatggaccgctctgcccctcagttggccaatctgcaggaatccttcatctca
cacattgtgggtcccttgtgccactcctatgactcggcagggctgatgccaggaaaatgg
gtggaagacagtgatgagtcgggagataccgatgacccagaagaggaggaggagggggaa
gaagaggcagatgcacccaacgaggaagaaacctgtgaaaatgaatctccaagaaagaaa
gctttcaaaaggaggaaaatctactgccaaataactcagcacctactgcagaatcacaag
atgtggaagaaagtcattgaagatgaacagcgattggcgggcatagaaaatcagtctgtg
gagcagacccttccacagccatcctcagaaaagatccaggctattgaggaagaagaagaa
gaaaaggggaaaccgagagcggaggaaatcccagccccacagcccaaccagtga
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