Ochotona princeps (American pika): 101529478
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Entry
101529478 CDS
T07609
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00230
Purine metabolism
opi00670
One carbon pool by folate
opi01100
Metabolic pathways
opi01523
Antifolate resistance
Module
opi_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101529478 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101529478 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101529478 (GART)
Enzymes [BR:
opi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101529478 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101529478 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101529478 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_3
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
Sacchrp_dh_NADP
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
101529478
NCBI-ProteinID:
XP_004594186
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All DBs
Position
14:complement(113043534..113070142)
Genome browser
AA seq
1010 aa
AA seq
DB search
MTARVLVIGNGGREHVLAWKLAQSRHIQQVLVAPGNAGTACSGKISNTAISVDNHAALAQ
FCKHENIVLVVVGPEAPLAAGVVDSLTSAGVRCFGPTAKAAQLESSKRFAKEFMDRHGIP
TARWRAFTSPEEACHFILSADFPALVVKASGLAAGKGVIVAENKEEACKAVQEMMQEKTF
GAAGETIVVEELLEGEEISCLCFTDGKTVTPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLLLEIKNTILQRAVDGMQQEGTPYIGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLFEVIQSALDGLLCMSLPAWLDDHTAVTIVMASQGYPGAYAKGVEITGFPEA
QALGLQVFHAGTALLEGRVVTNGGRVLAVTAIQETLISALEEAKKGLTLLKFAGSIYRTD
IGFRALAFLQRPRGLTYKDSGVDIAAGNMLVKKIQPLAKATSRRGCDVALGDFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFAC
GKLDLKTAEAVVAGIAKACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
RLERITEGDVVVGVASSGLHSNGFSLVRKIVAKSSLQYSSPAPAGCGDQTLGDLLLTPTR
IYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKLGVDLDARSWRIPRIFSWLQQEG
QLSEEEMARTFNCGVGAALVVAKEHTKLLLRDIQQRQEEAWVIGSVVARTKGSARVKVKN
LTAALQVDRSVLENSSLENHSPAHPKKARVAVLISGTGSNLQALIDSTQQPHSASRIAVV
ISNKAGVAGLEKAQRAGIPTRVINHKLYKDRVEFDNAIDQVLEEFSTDIVCLAGFMRILS
GPFVRKWTGKMLNIHPSLLPSFKGANAHEQALEAGVTVSGCTVHFVSEDVDAGQIILQEA
VPVKRGDTVATLSERVKLAEHKVFPAALELVATGAIQLGENGKICWAKGQ
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atgacagcccgtgttctggtcatcggcaatggaggcagggagcatgtgctggcctggaag
ctcgcacagtcccgtcatatccagcaggtgttggttgccccaggaaatgcagggactgcc
tgctctgggaagatttccaacactgccatctcagttgacaatcacgctgcccttgcccag
ttctgcaaacacgagaacattgtgttggtggtggttggacccgaggcacccctggccgcc
ggggttgttgatagcctgacatctgcaggagtgcgatgcttcggccccacagcaaaggca
gctcaactggaatctagcaagaggtttgccaaagagtttatggatcggcacggaatcccg
actgcacgctggcgagctttcaccagccctgaggaagcctgccacttcatcctgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggagtcattgtt
gcagagaacaaagaagaagcctgcaaggctgtgcaggagatgatgcaggagaaaaccttt
ggagcagctggagaaacaattgttgttgaagaacttcttgaaggtgaagagatttcttgt
ctgtgtttcactgatgggaaaacggtgacccccatgcctccagcacaggaccacaagcgc
ttactagagggagatcatggtcccaatacagggggaatgggagcctactgtccagcacct
caggtttctaaggacttgttactagaaattaaaaatactattcttcagagggcagtggac
ggcatgcagcaggagggcactccttacataggggttttgtatgctggtataatgctgacc
aaagatggcccgaaagttctggagtttaattgccgttttggtgatccagaatgccaagtg
attctcccactccttaaaagtgatctttttgaagtgattcagtccgccttagatggcctg
ctttgcatgtccctgcccgcctggctagacgaccacaccgctgtaactatagtcatggca
agtcagggttatcctggagcctatgccaagggtgtggagatcacagggtttcctgaggcc
caggctctgggactacaggtgttccatgcggggactgccctcttggagggcagagtagtg
acgaacgggggaagagtcctcgctgtcacagccatccaggagactctcatctcagccctc
gaggaagccaagaaaggactaactcttctcaagtttgcgggctccatttacaggacggac
attggcttccgcgcactagccttcctccagcggcccagaggcctgacttacaaggactct
ggagtggacattgcagctggaaacatgctggtgaaaaaaattcagccattagccaaagcc
acctcccggagaggctgtgatgttgctcttggagatttcgctggtctttttgatttgaaa
gcagctggcttcaaagatcctcttctggcctctggaacagatggtgttggaacaaaactg
aagattgctcagctctgcaataaacatgataccattgggcaagacttggttgcgatgtgt
gtaaatgacattctggcgcaaggcgcagagcccctcttcttcctggattactttgcctgc
ggaaaactcgacctcaagacagctgaagctgttgttgctggcatcgccaaagcgtgcggg
aaagctgggtgtgctctccttggaggtgaaacagcagaaatgcctgacatgtatcctccc
ggagagtatgaccttgctgggtttgctgttggtgccatggaacgggaccagaagctccct
cgtctggaaagaatcactgaaggggatgttgttgttggcgtagcttcatctggtctccac
agcaatggctttagccttgtgaggaagattgtagccaaatcttcgcttcagtactcctct
ccagcacctgctggttgtggtgaccagaccttaggggacctgcttttaactccaacaaga
atctacagccactcgttgttacccgtactccggtcaggtcatgtcaaggcttttgctcat
attaccggtggaggattgctggaaaatatccccagagtcctgcctcagaaacttggtgta
gatctagatgcccggagctggaggatccccaggatcttctcatggctgcagcaagaaggg
cagctctcggaggaggagatggccaggacgtttaattgtggggttggagctgcacttgtg
gtagcaaaggagcacacaaagctgcttctgagggacattcagcagcgccaggaggaagcc
tgggtgattggcagcgtggttgcccgaactaaaggttccgctcgtgtaaaagtcaagaat
ctgactgcagccttgcaagtggacaggtcagtgctggagaacagctccctggaaaatcat
tcccctgcccacccaaaaaaggcaagagtggctgtcttgatatccggaacaggttccaac
ctacaggcactcatagacagtactcagcagccacacagcgcctcgcgcatcgccgtcgtc
atctccaacaaagctggggtggctgggctagagaaggcacagagagctggcattcccacc
agggtgattaatcataaattatataaagatcgtgtagaatttgacaatgccattgaccaa
gttcttgaagaattctccacagacatagtctgtcttgcaggattcatgagaatactgtct
gggccgtttgttagaaaatggactgggaaaatgctcaacatccacccatccttgctccct
tccttcaagggtgcaaatgcacatgaacaagctctggaagccggggtcacagtcagcggc
tgcactgtgcacttcgtgtctgaggatgtagatgctggacaaattattttgcaagaagcg
gttccggtgaaaagaggtgacactgttgcaactctgtctgaaagagtaaagttagcagaa
cataaagtatttcctgcagccctcgagctggtggccactggagctatacagcttggagaa
aatggcaagatttgctgggccaaaggacaataa
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