Ochotona princeps (American pika): 101531220
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Entry
101531220 CDS
T07609
Symbol
IDH1
Name
(RefSeq) isocitrate dehydrogenase [NADP] cytoplasmic
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00020
Citrate cycle (TCA cycle)
opi00480
Glutathione metabolism
opi01100
Metabolic pathways
opi01200
Carbon metabolism
opi01210
2-Oxocarboxylic acid metabolism
opi01230
Biosynthesis of amino acids
opi04146
Peroxisome
opi05230
Central carbon metabolism in cancer
Module
opi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
opi_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101531220 (IDH1)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101531220 (IDH1)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101531220 (IDH1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101531220 (IDH1)
Enzymes [BR:
opi01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101531220 (IDH1)
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Gene cluster
GFIT
Motif
Pfam:
Iso_dh
XRN1_D2_D3
Motif
Other DBs
NCBI-GeneID:
101531220
NCBI-ProteinID:
XP_004576939
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Position
7:complement(90891132..90908337)
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AA seq
414 aa
AA seq
DB search
MSKKIHGGSVVEMQGDEMTRIIWELIKEKLIYPYVELDLHSYDLGIENRDATNDQVTKDA
AEAIKKYNVGVKCATITPDEKRVEEFKLKQMWKSPNGTIRNILGGTVFREAIICKNIPRL
VTGWVKPIIIGRHAYGDQYRATDFVVPGPGKVEITYTPNDGSQKVTYLVHNFEDCGGVAM
GMYNQDKSIEDFAHSSFQMALSKGWPLYLSTKNTILKKYDGRFKDIFQEIYDKQYKAKFE
AQKIWYEHRLIDDMVAQAMKSEGGFIWACKNYDGDVQSDSVAQGYGSLGMMTSVLVCPDG
KTVEAEAAHGTVTRHYRMYQKGQETSTNPIASIFAWTRGLAHRAKLDNNKELSFFANALE
EVCIETIEAGFMTKDLAACIKGLPNVQRSDYLNTFEFMDKLGENLKIKLSQAKL
NT seq
1245 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaaaaaatccatggcggctctgtggtggagatgcagggagatgaaatgacacga
attatttgggaattgattaaagaaaagctcatatatccttatgtggaactggatctgcat
agctatgacttgggtatagagaaccgtgatgccaccaatgaccaggtcaccaaggatgct
gcagaagctataaagaagtacaacgtgggcgtcaagtgtgctaccatcacccccgatgag
aagagagtggaagagttcaagctgaaacaaatgtggaagtcgcctaatggcaccatccga
aatattctgggtggcactgtcttcagagaagctatcatctgtaaaaacatcccccggctt
gtgactggatgggtgaaacccatcatcataggccgccatgcttatggggatcaatacaga
gcaaccgattttgttgttcctgggcctgggaaggtagagataacctacacaccgaatgac
ggatcccagaaggtgacatacctcgtacataactttgaagattgtggtggtgttgccatg
ggaatgtacaatcaggataaatcaattgaagattttgcacacagttccttccagatggct
ctgtctaagggttggcctttgtatctgagcaccaaaaacactattctgaagaaatatgat
ggacgttttaaagacatctttcaggagatatatgacaagcagtacaaagctaaatttgaa
gcccagaagatctggtatgaacataggctcattgatgacatggtggcccaagcaatgaaa
tcagaaggaggctttatctgggcctgtaaaaattatgatggcgacgtgcagtcagactct
gtggcccaaggatatggctcccttggcatgatgaccagtgtgctggtttgcccagatggc
aagacagtggaagcagaggctgcccatggaactgtaactcgtcactaccgcatgtaccag
aagggacaggagacatccaccaaccccattgcttccatttttgcctggaccagaggatta
gcccacagagccaagctggataacaacaaagagctcagcttctttgcaaatgctttggag
gaagtctgtattgagaccattgaggctggcttcatgaccaaggacctggcagcttgcatt
aaaggtttgccgaatgtgcaacgttctgactacttgaacacatttgagttcatggataaa
cttggagaaaacttgaagataaagctctctcaggcgaaactttaa
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