Ochotona princeps (American pika): 101531376
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Entry
101531376 CDS
T07609
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00790
Folate biosynthesis
opi01100
Metabolic pathways
opi01240
Biosynthesis of cofactors
opi01523
Antifolate resistance
opi04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
101531376 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101531376 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101531376 (FPGS)
Enzymes [BR:
opi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
101531376 (FPGS)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
101531376
NCBI-ProteinID:
XP_004593601
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Position
1A:complement(3814142..3822803)
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AA seq
574 aa
AA seq
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MSWARRHLHAALALAAVSARGATTEGAARRELSTRPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRGDPQAQLEAMELYLTRSGLQLEDLDRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGQPISRELFTKHFWRLYHRLEETKDDNYNSMPAYFRF
LTLMAFHVFLQEQVDLAVMEVGIGGAYDCTNIVRKPVVCGVSSLGMDHTNLLGDTMEKIA
WQKGGIFKCGVPAFTSLQPEGPLAVLRDRAQQISCPLYLCPPLEVLEEGGPPLSLGLEGE
HQRANAALALQLAHCWLRRQEHLGDGELKSSQPGVLWQLPLAPVFQPTERMRHGLRDTEW
LGRTQVLRRGPLTWYLDGAHTTSSIQACVRWFLGALPQQERRSVGLEVRVLLFNSTGDRD
SAALLKLLQPCQFDYALFCPNLTEVSFTGDADQQNFMVTLDQVLHRCLEHQQHWSRLNDS
VQSPHSPGQAGSLLHPSSSTSLVFSCISHALQWISQGRDPVFQSPNPPRGLLPFSLASSN
SKVLREATAVHVLVTGSLHLVGGVLKLLDPSLSQ
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagacacttgcacgccgccctggctctggcagcggtttctgctcgt
ggtgcaacgacagaaggagccgcgcggcgggaactgagcacgcggccggctccacaggag
cccggcatggaatatcaggatgccgtgcgcatgctcaataccctgcagaccaatgccagc
tacctggagcaggtaaaacgccagcggggtgacccccaggcccagctggaagccatggaa
ctctacctgacacggagtggtctacagttggaggacctggaccgcctcaacattattcac
gtcacggggaccaaggggaagggctccacctgcgccttcactgaacgcatccttcgaaac
tatgggttgaagacaggattttttagctctcctcacctggtacaggtacgtgagcggatc
cgcatcaatgggcagcccatcagccgcgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccaaggatgacaactacaactccatgcctgcctacttccgcttc
ctcacactcatggccttccacgtgtttctccaagagcaggtggacttggcggtgatggaa
gtaggcattggtggggcctatgactgtaccaacattgtcaggaagcctgtggtgtgcggt
gtctcctctcttggcatggaccacaccaatctccttggggacacgatggagaagattgca
tggcagaaggggggcatctttaagtgtggtgtcccagctttcacatctctccagcctgag
gggcccctggcggtgctcagagaccgagcacagcagatctcgtgtcccctctacctgtgc
ccaccactggaagtcctagaggagggcgggccgccgctgagcctgggcctggagggcgag
caccagcgggccaatgctgccctggccttgcagttagcgcactgctggctgcggcggcag
gagcacctaggtgatggcgagctgaagtcctcccagcccggcgtcctgtggcagctgccc
ctggcgcccgtgttccagcccacggagcgcatgcggcacgggcttcgggacacggaatgg
ctgggccgcacgcaggtgctgcggcgtgggcctctcacctggtacctggacggtgcgcac
accaccagcagcatacaggcctgtgtgcgctggttccttggggcgctgccgcagcaggag
agacggagtgttggcttggaagtacgtgtcctgctcttcaactccactggggaccgggac
tcagcagccctgctgaagctgctgcagccctgccaatttgactatgctctcttctgcccc
aacctgacagaggtgtcattcacaggcgacgcagaccagcagaactttatggtgaccctg
gaccaggtgctgcaccgctgcctggagcaccagcagcactggagccgactgaatgacagt
gtccagagcccccacagcccagggcaggcaggatccctgctccacccttccagcagcacc
tccttggttttcagctgtatttcgcatgccttgcagtggatcagccaaggccgggatcca
gtcttccagtcccccaaccccccgagaggtctcctgcccttctccctggccagcagcaac
agcaaggtactccgggaggctactgctgtccacgtgctggtcacaggcagcctgcatctt
gtgggcggtgtgctgaagctgctggacccctccctgtcccagtag
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