KEGG   Ochotona princeps (American pika): 101531453
Entry
101531453         CDS       T07609                                 
Symbol
MAPK10
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
opi  Ochotona princeps (American pika)
Pathway
opi01522  Endocrine resistance
opi04010  MAPK signaling pathway
opi04012  ErbB signaling pathway
opi04014  Ras signaling pathway
opi04024  cAMP signaling pathway
opi04068  FoxO signaling pathway
opi04071  Sphingolipid signaling pathway
opi04137  Mitophagy - animal
opi04140  Autophagy - animal
opi04141  Protein processing in endoplasmic reticulum
opi04210  Apoptosis
opi04215  Apoptosis - multiple species
opi04217  Necroptosis
opi04310  Wnt signaling pathway
opi04380  Osteoclast differentiation
opi04510  Focal adhesion
opi04530  Tight junction
opi04620  Toll-like receptor signaling pathway
opi04621  NOD-like receptor signaling pathway
opi04622  RIG-I-like receptor signaling pathway
opi04625  C-type lectin receptor signaling pathway
opi04657  IL-17 signaling pathway
opi04658  Th1 and Th2 cell differentiation
opi04659  Th17 cell differentiation
opi04660  T cell receptor signaling pathway
opi04664  Fc epsilon RI signaling pathway
opi04668  TNF signaling pathway
opi04722  Neurotrophin signaling pathway
opi04723  Retrograde endocannabinoid signaling
opi04728  Dopaminergic synapse
opi04750  Inflammatory mediator regulation of TRP channels
opi04910  Insulin signaling pathway
opi04912  GnRH signaling pathway
opi04914  Progesterone-mediated oocyte maturation
opi04917  Prolactin signaling pathway
opi04920  Adipocytokine signaling pathway
opi04926  Relaxin signaling pathway
opi04930  Type II diabetes mellitus
opi04931  Insulin resistance
opi04932  Non-alcoholic fatty liver disease
opi04933  AGE-RAGE signaling pathway in diabetic complications
opi04935  Growth hormone synthesis, secretion and action
opi04936  Alcoholic liver disease
opi05010  Alzheimer disease
opi05012  Parkinson disease
opi05016  Huntington disease
opi05017  Spinocerebellar ataxia
opi05020  Prion disease
opi05022  Pathways of neurodegeneration - multiple diseases
opi05132  Salmonella infection
opi05133  Pertussis
opi05135  Yersinia infection
opi05142  Chagas disease
opi05145  Toxoplasmosis
opi05152  Tuberculosis
opi05161  Hepatitis B
opi05162  Measles
opi05166  Human T-cell leukemia virus 1 infection
opi05167  Kaposi sarcoma-associated herpesvirus infection
opi05169  Epstein-Barr virus infection
opi05170  Human immunodeficiency virus 1 infection
opi05171  Coronavirus disease - COVID-19
opi05200  Pathways in cancer
opi05208  Chemical carcinogenesis - reactive oxygen species
opi05210  Colorectal cancer
opi05212  Pancreatic cancer
opi05231  Choline metabolism in cancer
opi05415  Diabetic cardiomyopathy
opi05417  Lipid and atherosclerosis
opi05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:opi00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    101531453 (MAPK10)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101531453 (MAPK10)
   04012 ErbB signaling pathway
    101531453 (MAPK10)
   04014 Ras signaling pathway
    101531453 (MAPK10)
   04310 Wnt signaling pathway
    101531453 (MAPK10)
   04668 TNF signaling pathway
    101531453 (MAPK10)
   04068 FoxO signaling pathway
    101531453 (MAPK10)
   04071 Sphingolipid signaling pathway
    101531453 (MAPK10)
   04024 cAMP signaling pathway
    101531453 (MAPK10)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101531453 (MAPK10)
   04137 Mitophagy - animal
    101531453 (MAPK10)
  09143 Cell growth and death
   04210 Apoptosis
    101531453 (MAPK10)
   04215 Apoptosis - multiple species
    101531453 (MAPK10)
   04217 Necroptosis
    101531453 (MAPK10)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101531453 (MAPK10)
   04530 Tight junction
    101531453 (MAPK10)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101531453 (MAPK10)
   04621 NOD-like receptor signaling pathway
    101531453 (MAPK10)
   04622 RIG-I-like receptor signaling pathway
    101531453 (MAPK10)
   04625 C-type lectin receptor signaling pathway
    101531453 (MAPK10)
   04660 T cell receptor signaling pathway
    101531453 (MAPK10)
   04658 Th1 and Th2 cell differentiation
    101531453 (MAPK10)
   04659 Th17 cell differentiation
    101531453 (MAPK10)
   04657 IL-17 signaling pathway
    101531453 (MAPK10)
   04664 Fc epsilon RI signaling pathway
    101531453 (MAPK10)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101531453 (MAPK10)
   04920 Adipocytokine signaling pathway
    101531453 (MAPK10)
   04912 GnRH signaling pathway
    101531453 (MAPK10)
   04914 Progesterone-mediated oocyte maturation
    101531453 (MAPK10)
   04917 Prolactin signaling pathway
    101531453 (MAPK10)
   04926 Relaxin signaling pathway
    101531453 (MAPK10)
   04935 Growth hormone synthesis, secretion and action
    101531453 (MAPK10)
  09156 Nervous system
   04728 Dopaminergic synapse
    101531453 (MAPK10)
   04723 Retrograde endocannabinoid signaling
    101531453 (MAPK10)
   04722 Neurotrophin signaling pathway
    101531453 (MAPK10)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101531453 (MAPK10)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101531453 (MAPK10)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101531453 (MAPK10)
   05208 Chemical carcinogenesis - reactive oxygen species
    101531453 (MAPK10)
   05231 Choline metabolism in cancer
    101531453 (MAPK10)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101531453 (MAPK10)
   05212 Pancreatic cancer
    101531453 (MAPK10)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101531453 (MAPK10)
   05170 Human immunodeficiency virus 1 infection
    101531453 (MAPK10)
   05161 Hepatitis B
    101531453 (MAPK10)
   05171 Coronavirus disease - COVID-19
    101531453 (MAPK10)
   05162 Measles
    101531453 (MAPK10)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101531453 (MAPK10)
   05169 Epstein-Barr virus infection
    101531453 (MAPK10)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101531453 (MAPK10)
   05135 Yersinia infection
    101531453 (MAPK10)
   05133 Pertussis
    101531453 (MAPK10)
   05152 Tuberculosis
    101531453 (MAPK10)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101531453 (MAPK10)
   05142 Chagas disease
    101531453 (MAPK10)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101531453 (MAPK10)
   05012 Parkinson disease
    101531453 (MAPK10)
   05016 Huntington disease
    101531453 (MAPK10)
   05017 Spinocerebellar ataxia
    101531453 (MAPK10)
   05020 Prion disease
    101531453 (MAPK10)
   05022 Pathways of neurodegeneration - multiple diseases
    101531453 (MAPK10)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101531453 (MAPK10)
   05418 Fluid shear stress and atherosclerosis
    101531453 (MAPK10)
   05415 Diabetic cardiomyopathy
    101531453 (MAPK10)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    101531453 (MAPK10)
   04936 Alcoholic liver disease
    101531453 (MAPK10)
   04932 Non-alcoholic fatty liver disease
    101531453 (MAPK10)
   04931 Insulin resistance
    101531453 (MAPK10)
   04933 AGE-RAGE signaling pathway in diabetic complications
    101531453 (MAPK10)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101531453 (MAPK10)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:opi01001]
    101531453 (MAPK10)
Enzymes [BR:opi01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     101531453 (MAPK10)
Protein kinases [BR:opi01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   101531453 (MAPK10)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 101531453
NCBI-ProteinID: XP_004590652
LinkDB
Position
15:complement(60910912..61194712)
AA seq 464 aa
MSLHFLYYCSEPTLDVKIAFCQGFDKQVDVSYIAKHYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIDEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLEASAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagcctccatttcttatactactgcagtgaaccaaccttggatgtgaaaattgccttt
tgtcaggggtttgataaacaagtggatgtgtcatatattgccaaacattacaacatgagc
aaaagcaaagtggacaaccagttctacagtgtggaagtgggggactcaaccttcacagtt
ctcaaacgctaccagaatctaaagcccattggctctggggctcagggaatagtttgtgct
gcctatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccctttcag
aaccaaacacatgccaagagagcttaccgggaactggtcctcatgaagtgtgtgaaccat
aaaaacattattagtttattaaatgtcttcacaccccagaaaacgctggaggagttccaa
gacgtttacttagtgatggaactgatggatgccaacttgtgccaggtgattcagatggaa
ctagaccacgagcgaatgtcttacctgctgtaccaaatgttgtgtggcattaagcacctt
cactctgctggaatcattcacagggatttaaagccaagtaacattgtagtcaaatcggat
tgcacattgaaaatccttgactttggcctggccaggacagcaggcacaagtttcatgatg
actccatatgtggtgacacgctattacagagcccctgaagtcatcctgggaatgggctac
aaggagaatgtggatatatggtctgtgggatgcattatgggagaaatggttcgccacaaa
atcctctttccaggaagggactatattgaccagtggaacaaggtcattgagcaactagga
acaccgtgtccagaattcatgaagaaattgcaacccacagtaagaaactatgtggagaat
cggcccaagtacgcaggactcaccttccccaagctctttccagattccctcttcccagca
gattccgagcacaataaactcaaagccagccaagccagggacttgttgtcaaagatgctg
gtgattgacccagcaaaacggatatcagtggatgacgccttacagcatccctacatcaat
gtctggtatgacccggccgaagtggaagcgcctccgcctcagatatatgacaaacagttg
gatgagagagaacataccatcgacgagtggaaagaacttatctacaaggaagtaatgaat
tcagaggaaaagactaaaaatggagtcgtcaaggggcagccttctccttcaggtgcagca
gtgaacagcagtgagagtctccctccatcctcatctgtcaacgacatctcctccatgtcc
acggaccagaccctggcatctgacactgacagcagcctggaagcctcggcgggacccctg
ggttgttgcaggtga

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