Ochotona princeps (American pika): 101533948
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Entry
101533948 CDS
T07609
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00260
Glycine, serine and threonine metabolism
opi00630
Glyoxylate and dicarboxylate metabolism
opi00670
One carbon pool by folate
opi01100
Metabolic pathways
opi01200
Carbon metabolism
opi01230
Biosynthesis of amino acids
opi01240
Biosynthesis of cofactors
opi01523
Antifolate resistance
opi04981
Folate transport and metabolism
Module
opi_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101533948 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101533948 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101533948 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101533948 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101533948 (SHMT1)
Enzymes [BR:
opi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101533948 (SHMT1)
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Gene cluster
GFIT
Motif
Pfam:
SHMT
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
101533948
NCBI-ProteinID:
XP_004599433
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Position
19:complement(53779346..53795434)
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AA seq
484 aa
AA seq
DB search
MATPVNGAARDATLWSSHERMLMQPLQDSDAEIYDIIKKESQRQRLGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEYIDELELLCQKRALQAYSLDPQSWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVHPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYQRLRKIADENGAYLMADMAHISGLVAAGV
VPSPFEHCHVVTTTTHKTLRGCRAGLIFYRKGVRSVDPKTGKEVLYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFKLYQRQVVANCRALAKALVELGYNIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQK
VAHFIHRGIELTVQIQDAVGPKATLKEFKEKLAGDEKHQRAVRALREEVESFASLFPLPG
VPGF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactcctgtgaacggggccgcccgggatgccacgctgtggtcctcccacgagcgc
atgctgatgcagcccctccaagacagtgacgctgagatttacgacatcatcaagaaggag
agccagcggcagaggctcggcctggagctcattgcctcggagaatttcgccagccgggca
gttctggaagctctaggctcctgcctgaataacaagtactcggaggggtacccgggccag
aggtattatggcggcactgagtacattgatgagctcgagctgctgtgtcagaaacgggcg
ctgcaggcctatagcctggacccccagagctggggggtcaacgtccagccctactcaggc
tcccctgccaactttgctgtgtacaccgccctagtggagccccatgggcgcatcatggga
ctagacctgccagacgggggccacctgacccacgggttcatgacagacaagaagaagatc
tcagctacatccatcttttttgaatctatggcctataaggtgcacccagacactgggtac
atcaactatgaccagctggaagagaatgcccgcctcttccaccccaagctcatcattgca
ggcaccagctgctactccaggaacctggactaccagcgcctgcgcaagatcgcggatgag
aacggggcctacctcatggcggacatggcgcacatcagcgggctggtggcggccggcgtc
gtcccctccccgttcgagcactgccatgtggtgaccaccactacccacaagacgctgcga
ggctgccgcgccggcctcatcttctacagaaaaggagtgcgcagtgtagaccccaagact
ggcaaagaggtgctgtacaacctggagtcactcatcaactctgccgtgttcccaggcctg
cagggcgggccccacaaccacgccattgccggggtggctgtggccttgaaacaagccatg
actccggagttcaagctgtaccagcgccaggtggtggccaactgcagggctcttgcgaag
gcccttgtggagctgggctacaacatagtgacagggggttctgacaaccatctgatcctt
gtggacctccgctccaaaggcacagatggtgggagggcagagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggagataaaagtgcgctgcggcccagtggc
ctgagactggggaccccagcattgacatctcgaggccttttggaaaaagacttccagaaa
gtcgcacacttcattcacagaggcattgagctgaccgtgcagatccaggatgctgtgggc
ccgaaggccaccctgaaggagttcaaggagaagctggctggggatgagaagcaccagagg
gcggtgcgggcgctgcgggaggaagtcgagagctttgcatccctcttccctctgcctggc
gtgcctggcttctga
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