Ochotona princeps (American pika): 101535483
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Entry
101535483 CDS
T07609
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi01521
EGFR tyrosine kinase inhibitor resistance
opi01522
Endocrine resistance
opi04010
MAPK signaling pathway
opi04014
Ras signaling pathway
opi04015
Rap1 signaling pathway
opi04066
HIF-1 signaling pathway
opi04068
FoxO signaling pathway
opi04081
Hormone signaling
opi04114
Oocyte meiosis
opi04140
Autophagy - animal
opi04144
Endocytosis
opi04150
mTOR signaling pathway
opi04151
PI3K-Akt signaling pathway
opi04152
AMPK signaling pathway
opi04211
Longevity regulating pathway
opi04213
Longevity regulating pathway - multiple species
opi04510
Focal adhesion
opi04520
Adherens junction
opi04550
Signaling pathways regulating pluripotency of stem cells
opi04730
Long-term depression
opi04913
Ovarian steroidogenesis
opi04914
Progesterone-mediated oocyte maturation
opi05200
Pathways in cancer
opi05202
Transcriptional misregulation in cancer
opi05205
Proteoglycans in cancer
opi05214
Glioma
opi05215
Prostate cancer
opi05218
Melanoma
opi05224
Breast cancer
opi05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101535483 (IGF1R)
04014 Ras signaling pathway
101535483 (IGF1R)
04015 Rap1 signaling pathway
101535483 (IGF1R)
04066 HIF-1 signaling pathway
101535483 (IGF1R)
04068 FoxO signaling pathway
101535483 (IGF1R)
04151 PI3K-Akt signaling pathway
101535483 (IGF1R)
04152 AMPK signaling pathway
101535483 (IGF1R)
04150 mTOR signaling pathway
101535483 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
101535483 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101535483 (IGF1R)
04140 Autophagy - animal
101535483 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
101535483 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101535483 (IGF1R)
04520 Adherens junction
101535483 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
101535483 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101535483 (IGF1R)
04914 Progesterone-mediated oocyte maturation
101535483 (IGF1R)
09156 Nervous system
04730 Long-term depression
101535483 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
101535483 (IGF1R)
04213 Longevity regulating pathway - multiple species
101535483 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101535483 (IGF1R)
05202 Transcriptional misregulation in cancer
101535483 (IGF1R)
05205 Proteoglycans in cancer
101535483 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101535483 (IGF1R)
05214 Glioma
101535483 (IGF1R)
05218 Melanoma
101535483 (IGF1R)
05215 Prostate cancer
101535483 (IGF1R)
05224 Breast cancer
101535483 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101535483 (IGF1R)
01522 Endocrine resistance
101535483 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
opi01001
]
101535483 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
opi04090
]
101535483 (IGF1R)
Enzymes [BR:
opi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101535483 (IGF1R)
Protein kinases [BR:
opi01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101535483 (IGF1R)
CD molecules [BR:
opi04090
]
Proteins
101535483 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Pkinase
Furin-like
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101535483
NCBI-ProteinID:
XP_004593221
LinkDB
All DBs
Position
17:complement(6927302..7135316)
Genome browser
AA seq
1368 aa
AA seq
DB search
MKAGFGGGSWTSLWGLLLIAVALLLWPTSGEICGPGIDIRNDFQQLKRLENCTVIEGFLH
ILLISKAEDYRNYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLHNLRNITRGAIRIEKNADLCFLSTVDWSLILDAVPNNYIVGNKPPKECGD
LCPGVLEGKPTCEKTAINNEYNYRCWTANRCQKMCPSSCGKRACSDNNECCHPECLGSCY
APDDNTACVACLHYYHDGTCVTSCPPNTYRFEGWRCVDRDFCANILSVDEGEGFVIHDGE
CMQECPSGFIRNGSQSMFCVPCEGPCPKVCEEDKKTKTIDSVNSAQMLQGCTIFKGNLLI
NIRRGNNIASELESFMGLIEVVTGYVKISHSHALVSLSFLKNLRLILGEEQLEGNYSFYV
LDNQNLQQLWDWEHRNLTIKTGKMYFAFNPKLCVSEIYRMEDVTGTKGRQSKGDINTRNN
GERASCESDILHFTNTATGKNRIILTWHRYRPPDYRDLISFTVYYKEAPHKNVTEYDGQD
ACGSNSWNMVDVDLPPDKDTEPGILLQGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEIL
YVRTNASVPSVPLDILSASNSSSQLIVKWSAPSLPNGNLSYYIVRWQQQPQDAYLYRHNY
CSKDKIPVRKYADGMIDFEEVTENPKMEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVF
ENFLHNSIFVPRPERKRRDVTHVTDAASSGRGRNTSAVDSYNTTDPDEPETDFPFFESRV
DREITVISNLRPFTSYRIDIHSCNHEAEKLGCSASNFVFARTKPAEGADDIPGPVTWETQ
PENSVFLKWPEPENPNGLILMYEIKYGSLMEDQRECISRQHYRKYGGIKLNRLNPGNYTA
RIQATSLSGNGSWTDPVFFYVPDKAADEGYSHLTVVLPVAIVFVVGGLVIMLYILHRKRT
RMGNGVLYASVNPEYFSAADVYIPDEWEVARDKITMNRELGQGSFGMVYEGVAKGVVKDE
PETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRG
DLKSYLRSLRPEIEQNNPAFAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVA
EDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVVLWE
IATLAEQPYQGFSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLDILG
SVKDELEPGFREVSFYYSDDNKAPEDDELELEPEDMESVPLDPSAAAAAAVAALGIPLPD
RHKPENGPGLGAMVLCASCEEQRRRPYSHMNGGRTDERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaaggctggcttcggaggagggtcttggacctcgctgtgggggctcctgcttatcgcc
gtcgcactcctgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aatgacttccagcagctgaagcgcctggagaactgcacggtgatcgagggcttcctgcac
atcctgctcatctccaaggccgaggactaccgcaactaccgcttccccaagctcaccgtc
atcactgagtacctgctgctcttccgtgtggctggcctcgagagcctgggagacctcttc
ccaaacctcacggtcatccgcggctggaagctcttctacaactatgccctggtcatcttc
gagatgactaaccttaaggacatagggctgcataacctgcggaacatcacccggggcgcc
atcaggatcgagaagaacgccgacctctgcttcctctccacggtggactggtcgctcatc
ctggacgctgtgcccaacaactacattgtgggaaacaagcccccgaaggagtgtggggac
ctgtgtccaggggtcctggaggggaagccaacgtgcgagaagaccgccatcaataacgaa
tacaactaccgctgctggaccgccaaccgctgccagaaaatgtgcccaagctcatgcggg
aagcgagcctgctcggacaacaacgaatgctgccaccctgagtgcctgggcagctgctat
gcacccgatgacaacacggcctgcgtggcctgcctccactactatcatgatggcacctgt
gtgacaagctgcccgcccaacacctaccgatttgagggctggcgctgcgtggaccgtgac
ttctgcgccaacatcctcagcgtcgacgaaggcgagggcttcgtcatccatgacggcgag
tgcatgcaggagtgcccctcggggttcatccgcaacggcagccagagcatgttctgcgtc
ccatgcgaaggtccttgccccaaggtctgtgaggaagacaagaaaacaaagaccattgat
tctgtaaattctgctcaaatgctccaaggctgcaccatcttcaagggcaatttgctcatt
aatatccgacgaggcaataacattgcctcagagctggagagcttcatggggctcatcgag
gtggtcacgggctacgtgaagatcagccactcgcacgccttggtctccttgtccttcctg
aagaacctgcgcctgattctcggagaggagcagctggaaggaaactactccttctacgtc
ctggacaaccagaacctgcagcagctctgggactgggaacaccgcaacctgaccatcaaa
accgggaagatgtacttcgccttcaatcccaaactctgtgtgtctgaaatttaccgcatg
gaggacgtgacagggactaaagggcgccagagcaaaggcgacattaacacccgcaacaat
ggagagagagcctcctgtgagagtgacatcctgcacttcaccaacaccgccaccggtaag
aaccgcatcatcctcacctggcaccgctaccggcccccggactacagggatctcatcagc
ttcaccgtctactacaaggaggcaccccataaaaacgtgacggaatatgatgggcaggac
gcctgtggctccaacagctggaacatggtggacgtggacctgcctccagacaaggacaca
gagcctggcatcctattgcaggggttgaagccctggactcagtatgccgtctatgtcaaa
gctgtgaccctcaccatggtggaaaacgaccacatccgtggggccaagagtgaaatctta
tatgttcgcaccaatgcttcagttccttccgtccccctggatattctctcggcatcgaac
tcctcttctcagctgatcgtgaagtggagcgccccctccctgcccaatggcaacctgagc
tactacatcgtgaggtggcagcagcagcctcaggacgcctacctgtaccgacacaattac
tgctccaaagataaaattcccgtgaggaagtacgcagatggcatgatcgactttgaagaa
gtaaccgagaatcccaagatggaggtgtgcggtggggagaaggggccgtgctgtgcctgc
cccaagaccgaagccgagaagcaggctgagaaagaggaggcggagtaccgcaaagtgttt
gagaacttcctgcacaactccatcttcgtgcccaggcctgagagaaagcgaagggacgtc
acgcacgtgactgacgctgcgtcgtccggccgaggcaggaacacctcggcggtggactcc
tacaacaccacggaccccgacgagcccgagacggatttccctttctttgagagcagagtg
gacagggagatcacggtgatctccaacctccgcccgtttacttcctaccgcatcgacatt
cacagttgtaaccacgaggccgagaagctggggtgcagcgcctccaactttgtctttgca
agaaccaagcctgcagaaggagcagatgacattcccggcccagtgacctgggaaacacag
ccggaaaactccgtctttctaaagtggccagaacctgagaatcccaacggattgatcctg
atgtatgagatcaaatatggctctctaatggaggaccagcgggagtgtatatccagacag
cactacaggaagtatgggggaatcaaactgaaccggctaaaccctggcaactacacagcc
cggattcaggccacgtctctctctgggaacgggtcatggaccgatcctgtgttcttctat
gtcccagacaaagctgccgacgaaggctactcgcacctgacagtcgtgctgcccgtggcc
atcgtgtttgtcgtgggagggctggtgataatgctgtacatcctgcacaggaagcgtacc
agaatggggaacggcgtgctctacgcctctgtgaacccggagtacttcagcgcggctgat
gtgtatatccccgatgagtgggaggtcgcacgtgataagatcaccatgaaccgagagctg
gggcagggctccttcgggatggtctatgaaggtgtcgccaaaggcgtggtcaaggatgag
cccgaaaccagggtggccatcaagaccgtgaacgaggccgccagcatgcgggaaaggatt
gaatttcttaatgaggcttccgttatgaaggagttcaattgtcaccatgtggtgcggttg
ctgggtgtggtgtctcagggccagccaaccctggtcatcatggagctgatgacacgaggg
gacctcaaaagctatctcaggtctctgcgaccggaaatagagcagaacaatccagccttt
gcccccccgagcctgagcaagatgatccagatggcgggcgagatcgcagacggcatggcg
tacctcaacgccaacaagttcgtccacagagacctggctgcccggaactgcatggtggcc
gaggacttcaccgtcaagatcggagactttggcatgacacgagacatctacgagacggac
tactaccgcaaaggagggaagggcctgctgcctgtgcgctggatgtcccccgagtccctc
aaagatggagtcttcactacccactctgatgtctggtcctttggagtcgtgctctgggag
atcgctacgctggccgagcagccgtaccagggtttctccaatgagcaggtcctgcgtttc
gtcatggagggcggcctactggacaagccggacaactgccccgacatgctgtttgagctg
atgcgcatgtgctggcagtacaaccccaagatgcggccttcgttcctggatatccttgga
agcgtcaaggacgagctcgagcccggcttccgtgaggtctccttctactacagcgacgac
aacaaggcgcccgaggacgacgagctggagctggagcccgaagacatggagagcgtgccc
ctggacccctctgctgccgccgccgccgccgtggccgccctcggcataccgctgcctgac
cgacacaagcccgagaacgggccggggctgggggccatggtcctctgcgccagctgcgag
gagcagcggcgacggccctactcgcacatgaatgggggccgtacggatgagcgggccctg
ccgctgccccagtcctccacctgctga
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