Ochotona princeps (American pika): 101535719 Help Entry 101535719         CDS       T07609                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism opi  Ochotona princeps (American pika) Pathway opi05014   Amyotrophic lateral sclerosis Brite KEGG Orthology (KO) [BR:opi00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     101535719 (SETX)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:opi03021]     101535719 (SETX) Enzymes [BR:opi01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      101535719 (SETX)     5.6.2.5  RNA 5'-3' helicase      101535719 (SETX) Transcription machinery [BR:opi03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      101535719 (SETX) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  AAA_11 AAA_12 AAA_19 AAA_30 UvrD-helicase AAA_22 ResIII NAT10_TcmA_helicase SLFN-g3_helicase UvrD_C_2 TniB nSTAND3 AAA_16 Motif Other DBs NCBI-GeneID:  101535719 NCBI-ProteinID:  XP_004593525 LinkDB All DBs Position 1A:783684..841924 Genome browser AA seq 2612 aa AA seqDB search MSTCCWCTPGGSSTVAFLKRYAAKAPPDDFRTAEEDLCYCLECVAEYHRARDELPFLHEV LWELETLRLINHFEKSMKAEIGDNDELYIVDNNGEAQLFDFSGLDFENKLRVPLLEILKY PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDSMDPFWPALHCFMVILDRL GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRSSSVRTKLEPESYLDDMVTCSQIVYSYN PEKTKKDAGWRSAICPDYCPNMYEEMETLANVLQSDIGQDMRVHNSTFLWFIPFVQSLMD LKDLGVAYIVEVIHHLHSEVKDVLNQTDAVCDKVTEFFLLILVSVIELHKNKKCLHLLWV SSQQWVEAVVKCAKLPSTAFARSCERSSGVTVSSSPANSVQLASVRLILSLLKEGHQLGQ QTLCKQYQDKLNGFIRQKNLSLGCQLTSQETHELQTCLKQIIRNIKFKVPQCNTSVDPTP TCKIPSVSCKEESDPMEKKFKKETHCLDNSSPTFSKEQMKADRHHMQENVLIQASSTVED NEENYMKDLKQGDDLSVQSCLKQNSRSHFTERARSQTKTSTGGQKSAEETCSCNLQKCSS RNGSERGCDVGVIASAPSVTDPGSGSLGKVSPSPLKGDGKISKPKTKAQKDEICAKLSDV LKKQSRRAASVADAVSVEEQVAVADAKSLHSRKDAADQSRAGFWQNLSLVPSGFLNCEKR ELENEELDSYTSHGNKCENQESPVGKNLGCCAELRPTSMNKTSPFRNCVTVRESGDKDMN KSTDVLLCNLAGDQGPGFSPKSDILTDSQVDRDLHKLSLIAQASVIKFPSDSTQRSSSPL QRKVKDDKRRFTADQDNAGDRSCGQVIIISDSDEEEEERLLDCEKHKKRDKECVHVCPEQ SASAASGEEKLPKGEVVRALLEAEGSESQLFEFESESEVYSAWQETKPEKIPVEESFRVM RAFSVTRAWDIADSGSKVCPGKGAKGMEGHTETQKRDVTGEECREVDIKPKRKRLEKPVA KEPVRPSSSTGNEEQAEEGRHHSGNDLESADERAVTPDSSADRATVALPRKPPCKLRTCR RGPRKTPAEARKGQNRSLSYLSCRTTPAVVPPKKFRQCPEPTSTVERLGLKKAPRRAFEL SQRSLDSLVQLRDHGKTVGVVETRKKSKLIPPQTLSVRNNKKLLVCQDVRLRRQVRPKSQ QNVQGFCDGHTGDAAGAEPHTAQVGEASVPECDTSDNGEQVVKCTPSEPETLKANSTSQV AAAAAALWNQCDSTVANERVPAAEVVASTSEEPVGGADLTARGMEVAGLKELEPECGSDA DETLFLTQNDPEDMDLCSQMETFDDQLIEVIHGAADSGSELQSESGHGPACEHRACAGTT SSPGEHCARPAEAGAAEDGVFRKPALPAAAKPLRPSTRKIFTSSSTSRIANLSKSLENTS ALRSSLKNKPSGRQSLPKEPLAVSAVSSKPMVEIQSLCNVGLPQVPNNPSRQRCTLPFGE SRSLFTSSPTNTLFASQSLSDAFVKEILKWKYEMFLNFDQCGPPASLCQSISRPVPVRFQ DCEDYFNIFLPLMILNTFETVAQEWISSPNKENFYQLHLRKFPGEQKKYREFVVYLEECE LAKQLHPKENDLVFLVPEQLNEETEDGERNCVQDLQKYHCGYVHKFRRTSVMRNGKSECS LSIQTQDDLPGKSNEIVKFKCVVISSLVTTQRKLKAMSLLSGRNQLARAVLNPCSMDFCM QELPTMSSERIIAYLRDFNEDQKKAIETAHAMVKHLPSVAKICLIHGPPGTGKSKTIVGL LYCLLTENQRKGHPDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLG NCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKELPSHVQEMHRRKEFLDRQLDELSR QRALCRGGREAQRRELDEKIARVSKERQELASKIKEVQGRPQKTQNIIILESHIICCTLS TSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVI SMKAQEYGYDQSMMARFYKLLEESVERNMLGRLPILQLTVQYRMHPDICLFPSNYVYNRS LKTSRLTETSRCSSDWPFQPYLVFDVGDGSERRDNDSYVNIQEIKLVMEIIKLIKDKKRD VTFRNIGIITHYKAQKTMIQKDLDREFDRKGPAEVDTVDAFQGRQKDCVIVTCVRANALQ GSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENPHWNHLIQDAQKRGAIIKTCDKNYR HDAMKILKLKPVFQRSLSHPLAAVPEAARPQGGLPSSALDSGLARTSFASSLYHTLSDTK VNTVTPTVPERLPGQEQLRDPRLLRRMATEAKGALLQEPQPVSPQHPGATPPSAEPGFPV ARQDASRAVQQAAGRAAALSTHRLYGQGGPPSAGPDAVSSRRRYELEGELGPQREARAFG EDRHERYYTRRASSWDRRRWEKEESGPKRRKL NT seq 7839 nt NT seq  +upstreamnt  +downstreamnt atgagcacgtgctgctggtgcactcccggcggctcttccaccgtcgccttcctcaagcgc tatgctgccaaggctccgcccgatgacttccgcacagccgaggaagacctgtgctactgc ctggagtgtgtggctgagtaccacagggccagggacgagctgcctttcttgcatgaggtt ttatgggaattagaaaccttacgtcttataaaccattttgaaaaatcgatgaaggcagaa attggagacaatgatgaattatatatagtggacaacaatggagaagctcagctgttcgac ttctctggcctggattttgaaaacaagcttcgcgttcctcttcttgagatcctgaaatat ccttacctgcttctgcatgagcgtgttaatgaattgtgtgttgaagcactttgtcgtatg gaacaggccaactgctcctttcaggtttttgacaaacatccggggatctatttatttttg gttcatcccaatgaaatggttcgacgctgggctatcctgactgcaagaaatttgggaaaa gtagacagagatgattactatgacttacaggaggttttaacttgcctttttaaagtcatt gagttggggcttttagaaagtcccgacatttatacttcttctgttcttgaaaaaggcaaa ctgattcttctgccttcacacatgtatgataccaccaactacaaaaactactggctgggg atttgcatgttgctgaccattcttgaggagcaagccatggactcactgctgttggggtca gacaaacaaaacgactttatgcaatcaatacttcacaccatggagagacaatcagatgat gacagtatggatcctttctggccagcactacactgcttcatggtgattctggatcgcctt gggtccaaggtctggggtcaacttatcgatcctattgaggcctttcaaaccattatcaac aatgtgagctacaacagagagatccagaacattcggagcagttctgtaaggaccaagtta gagccggagtcgtatttggatgatatggtgacttgtagccagattgtatacagttacaat cctgagaagaccaaaaaggatgcagggtggagatcagccatttgcccagattattgtcct aacatgtatgaagaaatggaaacattggccaatgtacttcagtcagatattggtcaagac atgcgtgttcataacagtaccttcctgtggttcatcccttttgttcaatccctcatggat ctcaaagatttgggtgtggcttacatcgtagaggttatccaccatctgcactccgaagtg aaagatgtcctcaatcaaacagatgcagtgtgtgacaaagtcactgaattttttcttttg attttggtgtcagtgattgaactgcataaaaataaaaaatgtttgcatttgctctgggtg agctcacagcagtgggtagaagcggtggtgaagtgcgccaagctccctagcactgcgttt gcgcggagttgtgagaggtcgtctggagtgaccgtgtcctcatcaccggccaactctgtc cagcttgcttctgtgcgtttgattctgagtctgctgaaagaaggtcaccagctggggcag caaaccctttgtaagcagtaccaggacaagctgaatgggttcattcgtcagaaaaattta tctctaggttgtcaactgactagtcaagaaacacacgaattacaaacttgtttaaaacaa attattagaaatataaaattcaaagtacctcagtgtaacacatctgtggatccgactcct acctgtaaaattccttctgtatcttgtaaagaagaaagtgaccccatggagaagaaattt aagaaagagacacattgtctagataattccagccccacattttctaaagaacaaatgaaa gctgacagacatcacatgcaagagaatgtattgatccaagcaagtagcactgtagaagat aatgaggaaaattatatgaaggatttgaaacaaggagatgatctgtcggttcagtcgtgc ttaaagcaaaatagtagaagtcattttactgaaagagctcgtagtcaaaccaaaacgagc acaggggggcagaagtcagcagaagagacctgttcatgcaacctgcagaagtgtagttca agaaatggttctgaaagggggtgcgatgtaggagtcatagcatccgcgccttctgtaact gatcctggctctggctcgctgggaaaagtgtccccatctccgttaaagggtgacggtaag atctccaaaccaaaaacgaaggcacagaaagacgagatctgtgcaaagttgtcagacgtc ctgaagaagcagagccggagagcagcttccgtcgctgatgctgtcagcgtcgaggagcag gtggctgtggctgacgcgaagagcttacattcaaggaaggatgcagccgatcagagcagg gccggcttttggcaaaatctgtctttagtccccagtggttttctgaattgtgaaaaaaga gaactggaaaatgaagagttagacagctatacttcccatggaaacaagtgtgaaaatcag gaaagccctgttggtaagaatctgggctgctgtgcagaattgaggcctacctcaatgaat aagacatctccctttagaaattgtgtgactgtacgtgaatcaggagacaaggacatgaac aagagtacagatgtgcttttgtgtaacctggcaggagaccagggccctggcttcagtcct aaatcggacatcttaacagattctcaggtagaccgagacctccacaaattatccttaata gctcaggctagtgttattaaatttccatcagattcaactcagagaagctcatccccgcta cagaggaaagtaaaagatgacaaaagacgttttacagccgaccaggataatgctggggac cgcagctgcggtcaggtcattataatttcagattctgatgaggaggaagaagagaggctt ctggattgtgagaaacacaagaaacgggacaaagaatgcgttcacgtctgtccagagcag agtgcttcggcagcctctggggaagaaaagctcccaaagggagaagtggtgagggccctc ttggaggctgagggcagtgagtctcagttgtttgagtttgaaagtgaatctgaggtatac tctgcttggcaagaaacgaaaccggagaagattccagttgaagaatcgtttagggtgatg cgtgcattcagtgtcacacgtgcttgggacattgcagacagtggttctaaagtgtgccct gggaagggggccaagggcatggaagggcacacggagacacagaagagggatgttactggc gaggagtgtcgtgaagttgacatcaaacctaagagaaaacgacttgaaaagcctgtggcc aaagagcctgtgaggccttcatcttctaccggaaatgaagagcaggctgaggaagggagg catcactctggaaacgatcttgagtctgcagatgagagagcggtgactcccgactccagt gctgacagagccactgtggctttgcccaggaaacctccctgcaagcttcgtacctgccgg agaggccctaggaagacgcctgcagaagccaggaaagggcagaacagaagtctcagctac ctgagttgtagaacaactcctgcagtagtaccgcctaagaaatttcgccagtgtcctgag ccaacttctacagttgagagacttggtctgaaaaaggctcctcgaagagcttttgaacta tcccagagatctttagattctttagttcagttacgtgaccatggcaaaactgttggagtg gttgaaacacggaaaaagagtaaattgatccctcctcagactctgtctgtaagaaataat aagaaactgctggtatgtcaagatgtccgtttgcgtaggcaggtgagacccaaatcccag cagaacgtacagggattctgtgatggtcacactggagatgctgcaggtgctgaaccacac acagcccaggttggtgaagcatctgtgccagaatgtgatacgtctgacaatggagagcag gtggtaaaatgcactccctctgaaccagaaaccctaaaagcaaattctacttctcaggtc gctgctgctgctgctgctctgtggaaccagtgtgattctacagtggcaaatgagagagtc ccagcagctgaagtagttgcttctacctcggaagagcctgtgggtggagccgacctgaca gcacgtgggatggaggtggcaggtttgaaggagctagagccggagtgcggcagtgacgct gacgagactttatttttaacccaaaatgatcctgaagatatggatctgtgttcacagatg gagactttcgatgatcaactgattgaagtaattcatggagcagctgattctggaagtgag ctgcagtcggagtcagggcatggcccagcgtgcgagcaccgagcctgtgctgggaccacg agcagccctggcgagcactgcgcgaggcccgcggaggctggggcggccgaggacggcgtg tttcggaagcctgccttgcctgctgctgctaaacctttgagaccttccactaggaagatt tttacctcaagtagcacttcccggattgctaatctttcaaagtcgttggagaacacttct gcccttcggtcatctctaaaaaataaaccaagtgggcgacagtctcttccaaaagaacca cttgcagtttctgcggtctcgtcaaagccgatggttgaaatccagagcttgtgcaatgtt ggccttcctcaggttccaaataatcccagcaggcagcgctgcacactgccgtttggggaa agcaggtctctcttcacttcgtctccaacaaacactctctttgcgtcacagtctctctct gatgcctttgttaaagagatcttaaagtggaaatacgaaatgtttttgaactttgatcag tgtggtcctccagcaagtctttgtcagtccatctccagacctgtgcctgtcagatttcaa gactgtgaagattattttaacatctttttgcctttgatgatactgaatacttttgaaaca gtggcccaggaatggatcagctctccaaacaaagagaacttctaccagttacatctgcgg aaatttcctggtgaacagaaaaaatacagggagtttgtagtttatctagaggaatgtgaa ctggctaaacagcttcacccaaaggagaatgatttggtgtttttggttcctgagcaacta aatgaagagacggaagatggagagagaaattgtgtacaagatctccagaaataccattgt ggttatgttcataaatttcgtcgcacttcagtcatgcgtaatgggaagtctgagtgttcc ctctccatccagactcaagacgatctgccaggcaaatcaaatgaaattgtgaaatttaaa tgtgttgtaatcagttctctggtgactacacagaggaagttgaaggccatgtctctgctg agtggtcggaaccagctggccagagccgtcctgaacccatgctccatggacttctgtatg caagagttaccaactatgtcatcggagagaattattgcttacttacgggatttcaacgag gatcagaagaaggcaatagagactgcgcacgccatggtcaaacacttaccgtcagtcgcc aaaatctgtttgattcatggaccacctggaacgggaaagtcaaaaacgattgtcggcctt ctctattgcttgctgacagagaaccagaggaaaggacaccctgatgagaacttcaacgcc aaaatcaaacagaaccgtgtccttgtgtgtgcaccttctaatgcagctgttgatgagctt atgaaaaaaattatcctcgaattcaaggaaaaatgtaaagacaagaagaatcctttggga aactgtggagatataaatttagtaagactgggtcctgaaaaatctattaataatgaagtt ctaaaattcagtttggacagccaggttaaccacaggatgaagaaagagttgccgtctcat gttcaggagatgcaccggagaaaagagttcctggaccgtcagctggatgagctttcccgc cagcgcgctctgtgccgaggcggacgggaggcacagaggcgagagttagatgaaaaaatt gccagagtttcaaaagaaaggcaggaacttgcttctaaaattaaagaggtccaaggtcgg ccccagaagacacagaacatcatcatcctggagtcgcacatcatctgctgcacgctgagc accagtggcgggctgctgctggagtcggccttccgcgggcaggggggcgtccccttcagc tgtgtcatcgttgatgaggccggacagtcttgtgaagtggagacgcttaccccactcatt catcgctgcaataagctgatccttgtcggggacccgaagcagcttcctcccaccgtcatt tccatgaaagcacaggagtatggctatgaccagtcaatgatggctcgcttctataaactg ctggaagaaagcgtggagcgcaacatgcttggcagactgcccatcttacagctgactgtc cagtaccggatgcacccagacatatgcctcttcccttccaattacgtctacaacaggagc ttgaagaccagcagactgactgagaccagccgatgttcatcagactggccgttccagcct tacctcgtgttcgatgttggagatggttccgagagacgggacaatgactcatatgtgaac attcaagaaataaaattggtgatggagataattaagcttatcaaagacaaaaaaagggat gtcacttttcggaacatcggcatcataacccactacaaggctcagaagacaatgattcag aaggatctggaccgagagtttgatagaaaaggaccagcagaagtggacacggtggatgcc ttccaggggcggcagaaggactgtgtcatcgtcacctgtgtccgggccaatgctctgcag ggctccattgggttcctggcaagtttgcagcgattgaatgtcactatcacgcgagccaag tacagcctctttatccttggacatctgaggacccttatggaaaacccacattggaaccac ctgattcaggacgcccagaagcgcggagccattatcaagacctgtgacaaaaactacaga catgatgccatgaaaatcctgaaactcaagcctgtgttccagagaagcctgagccacccg ctggccgccgtgcccgaggctgccaggccccagggcggcctgcccagcagcgcacttgac agcggcctcgccaggacgtcctttgcatcctctctctaccacacgctctccgacaccaaa gtaaacactgtgactcccacggtccccgagaggctcccgggccaggagcagctccgggac ccacggctgctcaggaggatggccaccgaggccaagggggctctcctacaggagcctcag ccagtgagcccccagcatcctggggccacacccccctcagcagagcctggctttcctgta gcgcggcaggatgcaagcagggctgtgcagcaggctgctggccgcgcagctgctctgagc acccacagactgtacgggcagggcgggcctccgagtgctggccctgatgctgtgagcagc aggagaaggtatgaactggaaggggagctgggcccccaaagggaggccagggccttcggt gaggacaggcacgagaggtactacacccggagggcctctagctgggacaggcggagatgg gagaaggaggagagcggccccaagagaagaaagctatag

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