Ochotona princeps (American pika): 101536127
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Entry
101536127 CDS
T07609
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
opi
Ochotona princeps (American pika)
Pathway
opi00310
Lysine degradation
opi01100
Metabolic pathways
opi05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
opi00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
101536127 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
101536127 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
opi03036
]
101536127 (DOT1L)
Enzymes [BR:
opi01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
101536127 (DOT1L)
Chromosome and associated proteins [BR:
opi03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
101536127 (DOT1L)
HMT complexes
Dot1-containing complex
101536127 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
101536127
NCBI-ProteinID:
XP_004595716
LinkDB
All DBs
Position
Unknown
AA seq
1692 aa
AA seq
DB search
MGDKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMSEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRDSKSNATTPTKAP
EGKAAGPATAAATTGATAAEAPADFGAEDEKAGVTTVKKASPSKARKKKLNRKGRKMAGR
RRGRPKKLSAVDPERKPRKSRAVLDALHTPAAPPTAPPSPQEPYRSPHSPFYQLPPGAQR
LPPNPLLTAPTPPALQKLLESFRVQYLQFLAYTKTPQYKANLQQLLDQEKEKKAQLLGTA
RQLFSHCQAQKEEIRRLFQQKLDELGVKALTYDDLIQAQKEICAHNQQLREQSEQLERDN
SQLRSQSLQLLKARCEELRLDWATLSLEKLLKEKQALKSQISEKQRRCLELQISIVELEK
SQRQQELLQLKSCVLPDEALPLHLRAKGPLGRELEAEPSRLHLELDCTKLSLPHLSSMSP
ELSMNGHAAGYEPCGAPSRPSSKQNTPQYLSSPLDQEVVPCTPGLGGRPRLDKLSALALP
ECTRLSPASVVLRRHPGQEHPGPARAAASEAAPRVEHAKENGLPYPSPCLSSGAKLSPQD
PRPPSPGPMPLLAEKSSEKGVKERAYSSSGDTITSLPISIPLSTVQPNKLPVSIPLASVV
LPSRAEKVGRSTPSPVSTLDKQIGANTHSAGSKGLAPTGFAYAGSVAITGPLGGSPAPLI
PGGEPAAFDESCSSSSLFVAVGSRSTTPQHPPLLGQPRTSGPASPAHQLAASPRLAGAAQ
GAVPDPSKGELPCDTGFSDPESEAKRRSVFTISSGAGSAKQSPSNKHSPLTSGPRGDSSQ
GHGQDRRKRGRRKRASAGTPSLGVSPKRRALPSVVGLFTPSSGSPLNLSSMVSNINQPLE
ITAISSPENSLKSSPTPYQDHDQPPVLKKERPLGPPNGAHYSPLTSDEEPGSEDEPGSAR
IERKIATISLDSKSPPKNLENGGGLAGRKLAPASEPVNSSKWKSTFSPISDVSLTKSADS
PLQASSASSQASLFAFRPALDEPGAAEPKLAAHPRKSFASSLAGADGHSPGAHPSNSFAL
GPGLASELGLHGFSDGASLAHKVPSDANPFFTKRQLEGLGGLKGEGGPAKEPGEPGLSLC
GPVDKAGPPHGSRAGKGRDRDHDGKNGHNLFISAAAAAAPPGGLLGGPGLVTAAPAAGSS
APGGQAHRPFLGTFGPGPQFMGPMSLQANLSSVAGSSVLQSLFGSVPAAAGLVHVSSAAA
RLTNSHTMGSFSGVAGGTVGGVFNHAVPPASAHLFGASVGSGAVCGSAPLGLSPLQAEIR
PPPPPAPPLAPAPPPPNVALPPTPTLLTANLDPVLLQSLTPVPVNINHVFLAPASAASLS
PTNPSLSVKLTPLSHKVSHPPFSVHPQPLPRLALAQAVPGIPQASSTGAPAVWVSLGMPP
PYAAHLSGRKPR
NT seq
5079 nt
NT seq
+upstream
nt +downstream
nt
atgggcgacaagctggagctgaggctcaagtcgcccgtcggggccgagcccgccgtctat
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagatcatcgagacc
atccggtgggtctgcgaggagatcccagacctgaagctcgctatggagaactatgtactc
atcgactacgacaccaaaagctttgagagcatgcagaggctgtgcgacaagtacaaccgt
gccatcgacagcattcaccagctgtggaagggcaccacccagcccatgaagctgaacacg
cggccgtccaatgggctgctgcggcacatcctgcagcaggtgtacaaccactcggtcacc
gaccccgaaaagctcaacaactacgagcccttctccccggaagtgtacggcgagacctcc
tttgacctggtggcccagatgattgacgagatcaagatgagtgaggacgacctgttcgtg
gacttgggcagcggtgtgggccaggttgtgctacaggtcgccgcggccaccaactgtaag
catcactacggcgtggagaaagcggacatcccggccaagtacgcggagaccatggatcga
gagttcaggaagtggatgaaatggtatggaaagaagcatgcagaatacacactggaaaga
ggcgatttcctctcagaagagtggagggagcgcattgccaacacgagtgtcatctttgtg
aataactttgcctttggtcctgaggtggaccaccagctgaaggagcgcttcgccaacatg
aaggaaggtggcaggatcgtgtcctcaaagcccttcgcgcctttgaacttcaggatcaac
agcaggaacctgagtgacatcggcactatcatgcgcgtggtggagttgtcccccctgaag
ggttccgtgtcatggacagggaagccagtgtcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtttgaaaaacccaaaactcagggaggaacaggaggcc
gctcggcgccgacagcagcgggacagcaagagcaacgccaccacccccaccaaggccccc
gaggggaaggcggctggcccagcgacagcagcagcgacaacaggggctaccgcagcggag
gcccctgcggactttggtgctgaggacgagaaggcaggggtgaccactgtcaagaaggcc
tctccctccaaggcccgcaagaagaagctgaacaggaagggccgcaagatggccggccgg
cggcgtgggcgccccaagaagctgagcgccgtggaccccgagcgcaaaccccgcaagagc
cgcgctgtgttggatgccctgcacaccccggccgcccctcccaccgcccctccctctccc
caggagccgtatagatcccctcacagcccattctaccagctacctccaggtgcgcagcga
ctgcccccaaacccgctgctcacggcgcccaccccacccgcgctgcaaaagctgctagag
tccttcagggtccagtacctgcagttcctggcctacaccaagacgccgcagtacaaggcc
aatctgcagcagctgctggaccaggagaaggagaagaaggcccagctgctgggcacagcc
cgccaactcttcagccactgtcaggcccagaaggaggagatccgtaggctcttccagcag
aagctggatgagctgggggtgaaggccctgacgtacgacgacctgatccaagcccagaag
gagatctgcgctcacaaccagcagctgcgggagcagtcggagcagctggagagggacaac
agccagctccgcagccagagcctgcagctgctgaaagcccgctgcgaggagctgcggctg
gactgggccacgttgtctctggagaagctgctgaaggagaagcaggccctcaagagtcag
atctcggagaagcagcggcgctgcctggagctgcagatcagcatcgtggagctggagaag
agccagcggcagcaggagctactgcagctcaagtcgtgcgtgctgcccgacgaagctctc
cccctgcacctgcgggccaagggcccgctaggccgcgagctggaggccgagcccagccgc
ctccatctggagctcgactgcaccaagctctcgctgcctcacctaagcagcatgagcccc
gagctgtccatgaacggccatgcggccggttacgaaccttgtggcgccccgagccggcct
tcgtccaagcagaacacgccccagtacttgtcctcaccgctggaccaggaggtggtaccc
tgcacccctggcctcggcggccggccccgcctcgacaagctgtcagcgttggccctgcct
gagtgcacaaggctgtccccagccagtgtggtgctgcggaggcacccaggccaggagcac
ccggggccggccagggctgctgccagtgaggcggccccaagggtggaacatgccaaggag
aacggcctcccctaccccagcccctgcctgtccagtggtgccaagctgagccctcaggac
ccgcggccaccgtcgcctgggcccatgccgctcctggccgaaaagagcagtgagaagggt
gtgaaggagcgagcctacagcagcagcggggacaccataaccagcctgcccatcagcatc
ccactgagcaccgtgcagcccaacaagctgcccgtcagcatccccctggccagcgtggtg
ctgcccagccgtgccgagaaggtgggtaggagcacccccagtcccgtgtcgacgctcgac
aagcagattggtgctaatacccacagcgcggggagtaaaggcctggccccgacaggtttt
gcctatgcgggctcggtggccatcacagggcccctgggcgggagcccagcccccctgata
cccggaggagagcctgctgccttcgacgagtcctgcagctccagcagcctcttcgtggct
gtgggctcccgcagtaccaccccacagcacccgcccctgctcggccagccccgcacctct
ggtcctgcctctcccgctcaccagcttgctgccagtccccggctcgctggggctgcccag
ggcgctgtccccgaccccagcaagggggaactcccctgtgataccggcttctcggatccc
gagagcgaagccaagaggaggagcgtcttcaccatctcgtctggcgcgggcagtgccaag
cagtcaccttccaacaagcacagccccttgacctccggcccccgtggtgacagcagccag
ggccacgggcaggacaggcgcaaacgtggccgcaggaagcgcgcctcagccgggacgccc
agcctgggggtgtcccccaagcgccgggcactgccatccgtcgtgggtctcttcacccca
tcctcagggtcccccctcaacctcagctccatggtcagcaacatcaatcagcccttggag
atcacggccatctcgtcccccgagaattccctaaagagctccccgaccccctaccaagac
cacgaccagccccccgtgctcaagaaggagcggcccctgggcccccccaatggggcccac
tactccccactgacgtcggacgaggagccgggctccgaggatgagcctgggagtgctcga
attgagaggaagattgcgacaatctccttagatagcaaatctcccccaaaaaacttggag
aatggtggtggcctggcagggaggaagctggctcccgccagcgagccggtcaacagcagc
aagtggaaatccaccttctcgcccatctccgatgtgagcctgaccaagtcggccgacagc
ccactgcaggccagctccgcctcgagccaggcctccctgtttgccttccgcccggccctg
gatgagccaggggctgctgagcccaagttggccgcccaccccaggaagagcttcgccagc
tccttggcaggggccgacggacacagcccaggggcccacccttccaacagcttcgcactg
ggcccgggcctggcctcggagctcggcctgcatgggttcagcgatggtgcttctcttgcc
cacaaggtcccctcggacgccaaccctttcttcaccaagaggcagctggaaggcctgggc
ggcctcaagggcgagggcggcccggccaaggagccaggcgagccgggcctgtccctgtgt
gggcccgtggacaaggccggccccccccacggcagcagggccggcaaggggcgggaccgc
gaccacgacggcaagaatggccacaacctcttcatctctgcggcggcggcggcggcgccc
cccggcggcctcctcggcggccctggcctcgtgacggcagctccagcggcaggcagctcg
gcacccggcggccaggcgcaccgccccttcctgggtacttttgggcctgggccacagttc
atgggccccatgtccctgcaggccaacctgagctcggtggccggctcgtccgtgctccag
tccttgtttggctctgtgccggccgccgcgggcctggtgcacgtgtcctccgctgcggcc
agactgaccaactcccacactatgggcagcttctccggggtggcaggcggaaccgtcgga
ggtgtctttaaccacgcggtgcctcccgcctctgctcatctgtttggagccagtgtcggc
agtggggctgtgtgtggcagcgccccactgggcctgagcccgctgcaggccgagattcgg
cccccccctccgccagccccgcccctggcccccgccccgccgccccctaacgtggccttg
cctcccaccccaacgctgctgaccgctaacctggaccccgtgctgctgcagagcctcacg
cccgtccccgtcaacattaaccatgtcttcctagctcctgcctcagctgcctctctgtct
cccactaacccctctctctctgtcaagctcacgccactctcgcataaggtctcccacccg
cccttctcggtgcacccgcagcctctgccccggctggccctggcacaggccgtgcccggc
atcccgcaggccagctccacgggcgcacccgctgtgtgggtttctcttggcatgccgcct
ccttatgccgcgcacctttcggggcgtaagccgcgctaa
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integrated database retrieval system
