Obesumbacterium proteus: DSM2777_03965
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Entry
DSM2777_03965 CDS
T04310
Symbol
metL
Name
(GenBank) bifunctional aspartokinase II/homoserine dehydrogenase II
KO
K12525
bifunctional aspartokinase / homoserine dehydrogenase 2 [EC:
2.7.2.4
1.1.1.3
]
Organism
opo
Obesumbacterium proteus
Pathway
opo00260
Glycine, serine and threonine metabolism
opo00261
Monobactam biosynthesis
opo00270
Cysteine and methionine metabolism
opo00300
Lysine biosynthesis
opo01100
Metabolic pathways
opo01110
Biosynthesis of secondary metabolites
opo01120
Microbial metabolism in diverse environments
opo01230
Biosynthesis of amino acids
Module
opo_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
opo_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
opo_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
opo00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
DSM2777_03965 (metL)
00270 Cysteine and methionine metabolism
DSM2777_03965 (metL)
00300 Lysine biosynthesis
DSM2777_03965 (metL)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
DSM2777_03965 (metL)
Enzymes [BR:
opo01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
DSM2777_03965 (metL)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
DSM2777_03965 (metL)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
NAD_binding_3
HTH_11
Motif
Other DBs
NCBI-ProteinID:
AMO80271
UniProt:
A0A4Q9D2B9
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All DBs
Position
811165..813600
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AA seq
811 aa
AA seq
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MSAQPVAGQAVGRQLHKFGGSSLADVKCYLRVAGIMAEYSAPGDMMVVSAAGSTTNQLIS
WLRLSQTDRISAHQVQQALRRYQSELITGLLPAELAEPLVALFTQDLERLAALLDEPMCD
ATYAEVVGHGEIWSARLMSALLNVKGMESEWLDARSFLRAERSAQPQVDEGRSYPLLQQL
LAQHPNKRLVATGFICRNDAGETVLLGRNGSDYSATQIGSLAGVSRVTIWSDVAGVYSAD
PRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSASDIDLQLRCSYQPEQGSTRIE
RVLASGTGAKIVTSHDEVCLIELNVPQSHDFEHVRQEIDRVLKRSQLRPLATGVHRDRHM
IQLCYTAEVVESAMKLLEESGVPGLLQLREGLALVALVGAGVCKNPLHSHRFYQQLKDQP
IEFFCQSEDSISLVAVLRRGPTEALIQGLHTTLFRAEKRVGLVLMGKGNIGSRWLELFAR
EQENISARSGFEFVLAGVVDSSRSLLNYEGLDASRALAFFDDEAQEMDEESLFLWMRAHP
YDDLVVLDVTASESLAQQYRDFASYGFHVISANKLAGASCSDDYRQIRDAFEKTGRHWLY
NATVGAGLPVNYTVRDLRDSGDSILSISGIFSGTLSWLFLQFDGTVPFTELVDQAWQQGL
TEPDPRVDLSGQDVMRKLVILAREAGYDIEPNQVRVESLVPAGCEGGSIDHFFENGEDLN
EQMIQRLEAANEMGLVLRYVARFDANGKARVGVEAVRPEHPLAALLPCDNVFAIESRWYR
DNPLVIRGPGAGRDVTAGAIQSDLNRLAALL
NT seq
2436 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcacaaccggtagcggggcaggcggtaggacgccagctgcataagtttggcggc
agtagtttagccgatgtgaaatgttatctgcgcgtcgcagggattatggctgagtacagc
gcccctggcgatatgatggttgtttccgcagcaggtagcaccaccaaccagctgattagc
tggttgaggctaagccagactgaccggatctctgcgcatcaggttcagcaggcgttacgt
cgctatcagagcgaactcatcacgggtctgttgcccgctgaacttgccgaacctttggtt
gcgctctttactcaggacttggagcgcttagccgctttgctcgacgagccgatgtgcgat
gcgacctatgcggaagtggtgggccacggtgagatttggtctgcacgcttgatgtcggcg
ctgctcaacgtgaaaggtatggagtcagaatggctggatgcgcgtagtttcctgcgtgcc
gaacgttctgctcagccacaggttgatgaaggccgatcttatcctctattacagcaactt
ctggcgcagcaccctaacaaacgcctcgtcgccacgggctttatctgccgtaacgatgcg
ggtgaaaccgtgctgttaggacgtaatggttctgactattccgctactcagattggctca
ttagcgggcgtttctcgcgtgacgatttggagcgacgtggccggtgtgtacagcgctgac
ccacgtaaggttaaagatgcttgcctgttgccgttgctgcgtttagatgaagccagcgaa
ctggcacgcttagccgctccggttttacatgcgcgcacgttgcagccggtttccgctagc
gatattgatttacagctacgctgtagctatcagccagagcagggctcaacgcgtattgaa
cgtgttttggcttcaggcaccggtgcgaaaattgtcaccagccacgatgaagtttgcctg
attgagcttaacgttccgcaaagtcatgattttgaacatgtgcgtcaggaaattgaccgc
gtgctcaagcgctctcagctgcgtccattagcgaccggcgtgcatcgtgaccgccatatg
atccagctgtgctataccgctgaagtggtggaaagcgcgatgaagctgttggaagagtct
ggcgttccgggtttgctacagctgcgcgaaggattggcgctggtggcattagtcggtgca
ggcgtatgcaagaatccactgcacagccaccgtttctatcagcagttaaaagatcagcca
attgagttcttctgccagtcagaagacagcatcagcttggtggcagtattgcgccgtggc
ccaactgaagctctgattcaaggtttgcacaccacgctgttccgtgcggaaaaacgcgtt
ggactggtattgatgggcaagggcaacatcggttcgcgctggttagaactgtttgcgcgt
gagcaggaaaacatttctgcccgcagcggctttgaatttgtactggctggcgtggtggat
agcagccgcagcttgttgaattatgaaggtttagacgcgagccgcgcattagcattcttt
gatgatgaagcgcaggaaatggatgaagaaagcctgttcctgtggatgcgcgcccatcct
tatgacgatttagtggtgctggatgtcacggcgagcgagtcgttagcgcagcagtatcgt
gattttgccagctatggtttccacgttattagtgcgaacaaattggccggtgcatcgtgc
agcgatgattatcgccaaatccgtgatgcctttgagaaaaccggccgtcactggctgtat
aacgccaccgtgggtgctggtttgccggtgaactatacggttcgcgatctgcgtgacagc
ggcgattctatcttgtcgatcagcgggattttctccggtacgttatcttggctattcctg
caatttgacggaacggttccgtttaccgaattggtcgatcaagcgtggcagcaaggactg
actgagcccgatccgcgcgttgatctctctggtcaagacgtgatgcgtaagctggtgatc
ttggcgcgtgaggctggttatgacattgaaccgaatcaggtgcgtgtggaatcgctggtg
ccggcgggctgcgaagggggatctatcgatcacttcttcgaaaacggtgaagacctgaac
gaacaaatgatccagcgtttagaagctgccaatgaaatgggtctggtgctgcgctatgtc
gctcgatttgacgccaacggtaaagcgcgggttggcgtggaagccgtccgtccagaacat
ccactggcggcgctgttgccatgtgacaacgtgtttgccattgaaagccgctggtatcgt
gataatccgctcgttatccgtggcccgggcgcaggacgagatgtgacggcgggggctatt
cagtcggatttgaatcggttggcggcgctgttgtga
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