KEGG   Odobenus rosmarus divergens (Pacific walrus): 101364741
Entry
101364741         CDS       T05148                                 
Symbol
TPH1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00380  Tryptophan metabolism
oro00790  Folate biosynthesis
oro01100  Metabolic pathways
oro04726  Serotonergic synapse
Module
oro_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:oro00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    101364741 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    101364741 (TPH1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    101364741 (TPH1)
Enzymes [BR:oro01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     101364741 (TPH1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT ACT_4 zf-C2HE
Other DBs
NCBI-GeneID: 101364741
NCBI-ProteinID: XP_004412522
UniProt: A0A2U3WT29
LinkDB
Position
Unknown
AA seq 444 aa
MIEDNKENKDHSLEKGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTVKEDGMETVPWFPKKISDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEGEIKTWGTVFQE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEEAVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHSLSGHAKVKPFDPKITC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSIQILKDTKSITSA
MNELQHDLDVVSDALAKVSRQPSI
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgattgaagacaataaggaaaataaagaccattccttagaaaaaggaagagcaactctc
attttttccttgaagaatgaagttggtggacttataaaagcactgaaaatcttccaggag
aagcatgtgaacctgttacatattgagtcccgaaaatcaaagagaagaaactcagaattt
gagatttttgttgactgtgatatcaacagagaacaattgaatgacatttttcatctgttg
aagtcccatactaacgttctctctgtgaatccaccagacaattttactgtgaaggaagat
ggtatggaaactgttccttggtttccaaagaagatttctgacctggaccattgtgccaac
agagttctgatgtatggttctgaactggatgcagatcatcctggcttcaaagacaatgtc
taccgtaaaagacggaagtattttgcagacttggctatgaactataaacatggagacccc
attcccaaggttgaattcactgaaggggagattaagacctggggaactgtgttccaagag
ctcaacaaactttacccaacccatgcctgcagagagtatctcaaaaacttacctttgctt
tctaaatattgtggataccgggaagataatatcccacaattggaagatgtctcaaacttt
ttaaaagagcgcacgggtttttccatccgtcccgtggctggttacttatcaccaagagat
ttcttatcaggtttagccttccgggtttttcactgcacacagtacgtgagacacagttca
gaccctctctataccccagagccagatacttgccatgaactcttaggtcatgtccccctt
ttggctgaacctagttttgcgcaattctcccaagaaattggcctggcttcccttggagct
tcagaggaggctgttcaaaaactggcaacgtgctactttttcactgtggagtttggtctc
tgtaaacaagacgggcagttgcgagtctttggtgctggattactttcttctatcagtgaa
ctgaagcattcactttctggacatgccaaagtaaagccctttgatcccaagattacctgc
aaacaggagtgtctcatcacaacttttcaggatgtctactttgtatctgaaagctttgaa
gatgcaaaggagaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag
tataatccatacacacggagcattcagatcttgaaagacaccaagagcataaccagcgcc
atgaatgagctgcagcatgatctcgatgttgtcagtgatgcccttgcgaaggtcagcaga
cagccaagcatctga

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