Odocoileus virginianus (white-tailed deer): 110140062
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Entry
110140062 CDS
T10722
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
ovr Odocoileus virginianus (white-tailed deer)
Pathway
ovr04022
cGMP-PKG signaling pathway
ovr04068
FoxO signaling pathway
ovr04081
Hormone signaling
ovr04140
Autophagy - animal
ovr04152
AMPK signaling pathway
ovr04211
Longevity regulating pathway
ovr04213
Longevity regulating pathway - multiple species
ovr04910
Insulin signaling pathway
ovr04920
Adipocytokine signaling pathway
ovr04923
Regulation of lipolysis in adipocytes
ovr04930
Type II diabetes mellitus
ovr04931
Insulin resistance
ovr04932
Non-alcoholic fatty liver disease
ovr04935
Growth hormone synthesis, secretion and action
ovr05010
Alzheimer disease
ovr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ovr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
110140062 (IRS2)
04022 cGMP-PKG signaling pathway
110140062 (IRS2)
04152 AMPK signaling pathway
110140062 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
110140062 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
110140062 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
110140062 (IRS2)
04923 Regulation of lipolysis in adipocytes
110140062 (IRS2)
04920 Adipocytokine signaling pathway
110140062 (IRS2)
04935 Growth hormone synthesis, secretion and action
110140062 (IRS2)
09149 Aging
04211 Longevity regulating pathway
110140062 (IRS2)
04213 Longevity regulating pathway - multiple species
110140062 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
110140062 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
110140062 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
110140062 (IRS2)
04932 Non-alcoholic fatty liver disease
110140062 (IRS2)
04931 Insulin resistance
110140062 (IRS2)
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Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
110140062
NCBI-ProteinID:
XP_020753976
UniProt:
A0A6J0XXS8
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Position
8:26188182..26219181
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AA seq
1330 aa
AA seq
DB search
MASPPEHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEA
GAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDE
YFAVAAENEQEQEGWYRALTDLVSEGRAGSGDAPPAAAAATSGSCSASLPGALGGSAGAA
AADDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSV
TLQLMSIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELF
EFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSA
CRVRTASEGDGGAAAAAMGAGAGAGAAAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGR
AGKAALAPAGGGLQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHP
LHPQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRVYCGRRSNTPESVAETPPARDGSA
GELCGYMAMERPLSHCGGRAYRRVSGDGAPDLDRGLRKRTYSLTTPARQRPAPQPSSASL
DEYTLMRATFSGSSGRLCPSCSASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYVP
MTPGVALLGPGSGSCKSDDYMPMSPTSVSAPKQILQPRPGPAALPPAGPAVPTPVSAASR
AFPGTAGGYKTGSPAESSPEDSGYMRMWCGSKLSMESADSKLLPNGDYLNMSPSDAGTAG
TPPDFFSAAGETLRGVPGYCYSSLPRSYKAPHACHGDSDQYVLMSSPVGRVLEEEQLEPA
PGPAQAASAFPAAAAGSGHPQPPHPAVPSPGRPGGGGGSRPDGFLAQRCRAVRPTRLSLE
GLPALPRMHEYPLPPEPRSPGEYINIDFGEAGARLSPPAPPLLASAASSSSLLSASSPAS
SLGSGTPGTSGDSRQRSPLSDYMNLDFSSPKSPQPGAQGRDPVGSLDALLSPEASVYPPL
PPRPAASSSALQPPPLPPPPGELYRLPVATTSQGPGAASDTGDNGDYTEMAFGVAATPPQ
PIAAPPKPDGARVSSPVSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADPQGGRR
RHSSETFSSTTTVTPVSPSFAHTPKRHNSASVENVSLRKGSEGGCGGGLGGGDEPPSSPR
QLPPPTPQQARAWTSAQPGGSLVGCPGGNSSPMRRETSAGFQNGLNYIAIDVRDEPGLSP
PLQQHPHGQTGDRSAWGRTRSLGGLISAVGAASPAGVCGGPGPGALPGANAYASIDFLTH
HLKEATVVKE
NT seq
3993 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccggagcacgggccccccgggccggcgggcggggacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgcgggcggcgacgaggcg
ggggcgggcgggggcccggcgccgcagccgccgcgtctcgagtactacgagagcgagaag
aagtggcggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaac
atcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaaggacgag
tacttcgccgtggcggctgagaacgagcaggagcaggagggctggtaccgcgcgctcacc
gacctggtcagcgagggccgcgcgggctccggcgacgcgccccccgccgccgccgccgcc
acctccgggtcctgcagcgcctccctgcccggcgccctgggcggctctgcgggcgccgcc
gcggccgatgacagctacgggctggtggcgcccgccacggccgcctaccgcgaggtgtgg
caggtgaacctgaagcccaagggcctgggccagagcaagaacctgacgggcgtgtaccgc
ctgtgcctgtcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtg
acgctgcagctcatgagcatccgccgctgcggccactcggacagcttcttcttcatcgag
gtgggccgctcggccgtcacgggccccggcgagctgtggatgcaggcggacgactcggtg
gtggcgcagaacatccacgagaccatcctggaggccatgaaggcgctcaaggagctcttc
gagtttcggccgcgcagcaagagccagtcgtccggctcgtcggccacgcaccccatcagc
gtgcccggcgcgcgccgccatcaccacttggtcaacctgcccccgagccagacggggctg
gtgcgccgttcgcgcaccgatagcctggccgccaccccgcccgccgccaagtgcagcgcg
tgccgggtgcgcacggccagcgagggcgacggcggcgcggcggcggcggcgatgggggcc
ggggcgggggccggggcggcggcggcgggcggcaggccggtgtcggtggcgggcagcccc
ctgagcccgggcccggtgcgcgcgccactgagccgctcgcacacgctgagcggcggccgc
gcgggcaaggcggcgctggcgccggcagggggcggcctgcagcacagccgctccatgtcc
atgcccgtggcgcactcgcccccggcggccaccagccccggcagcctgtcgtccagcagc
gggcacggctcgggctcctacccgccgccccccggcccgcacccgcacctgcagcacccc
ctgcacccccagcgcccctccagcggcagcgcctcggcctcgggctcccccagcgacccc
ggcttcatgtccttggacgagtacggctccagccccggggacctgcgggtctactgcggc
cgccggagcaacacgcccgagtccgtcgccgagacgcccccggcgcgggacggcagcgcg
ggcgagctgtgcggctacatggccatggagcggccgctgagccactgcggcggccgcgcc
taccgcagggtctccggggacggcgccccggacttggaccgagggctgaggaagcggact
tactcgctgaccacgcctgcccggcagcggccggcgccccagccgtcctccgcgtccctg
gacgagtacacgctgatgcgggccaccttctcgggcagctccggccgcctgtgcccgtcc
tgcagcgcgtcctctcccaaagtggcctaccacccgtaccccgaggactacggcgacatc
gagattggctcacaccgcagctctagcagtaacctgggcgcggacgacggctacgtgccc
atgacccccggcgtggccctcctggggccgggcagcgggagctgcaagagcgacgattac
atgcccatgagccccaccagcgtgtcggccccgaagcagatcctgcagccacgccccggg
cccgccgccttgccccctgcggggccagcggtacccacgcccgtgtcggcggccagcagg
gccttcccgggcaccgcgggcggctacaagaccggctccccggccgagagttcccccgag
gacagcgggtacatgcgcatgtggtgcggttccaagctgtccatggagagcgccgacagc
aagctgctgcccaacggggactacctcaacatgtcccccagcgacgcgggcaccgcgggc
accccgcccgacttcttctctgctgcgggggagacgctgcggggcgtgcccggctactgc
tatagctccctgccccgctcctacaaggccccccatgcctgccacggcgacagcgaccag
tacgtgctcatgagctcgcccgtgggccgcgtcctggaggaggagcagctggagccggcc
cccggccccgcgcaggcggccagtgccttcccggccgcggcggctggcagcggccacccc
cagccaccccaccctgccgtgccttcgcctgggaggccaggcggtggcggaggtagccgc
cccgacggcttcctggctcagcgctgccgggcagtgcggcccacgcgcctgtccctggag
gggctgccggctctgccccgcatgcacgagtacccgctgccccccgagcccaggagtccg
ggcgagtatatcaacatcgacttcggggaggccggcgcgcgcctgtcgccgcccgcgccc
ccgctcctggcctcggccgcctcctcgtcgtcgctgctgtccgccagcagcccggcctcg
tccctgggctccggcaccccgggcacgagcggggacagccggcagcgctccccgctctcc
gactacatgaacctcgacttcagctcgcccaagtcgccgcagccgggcgcccagggccgg
gaccccgtgggctccttggacgctctgctgtcccccgaggcctctgtgtacccgccgctg
ccccctcgcccggccgcctcctcctcggccctgcagccgccgcccctgccgcccccgccg
ggtgagctgtaccgcctgcctgtggcaaccacctcccagggcccaggcgcggcctcggac
acgggggacaacggtgactacaccgagatggccttcggcgtggccgccaccccgccgcaa
ccaatcgcggcgcccccgaagcccgacggtgcccgcgtgagcagccccgtgtctggcctc
aagaggctgagtctcatggatcaggtgtcaggggtcgaggccttcctgcaggccggccag
cccccagacccgcaccggggggccaaggtcatccgcgcggacccgcaggggggccgccgc
cgccacagctccgagaccttctcttcgaccaccactgtgacccccgtgtccccgtccttc
gctcacacccccaagcgtcacaactcggcctcggtggagaacgtttctctcaggaaaggc
agcgaagggggctgcggcggcggcctgggtgggggtgacgagcccccctcgtcaccgcgc
cagttgcccccgccgacgccgcagcaggcgcgggcctggacgtcggctcagcccggcggc
agcctggttggttgtcccgggggcaacagctcgccgatgcgccgggagacgtccgccggc
tttcagaatggcctcaactacatcgccatcgacgtgagggacgagccggggctgtcaccg
cccctgcagcagcacccacacgggcagacgggcgacaggagcgcctggggccgcacccgg
agcctcgggggtctcatcagcgccgtgggcgctgccagccccgccggggtgtgcgggggg
ccaggccccggtgccctgcccggggccaacgcctacgccagcatcgacttcttgacgcat
cacctgaaagaggccacagtggtgaaagagtga
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