Cutibacterium acnes C1: PAC1_05210
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Entry
PAC1_05210 CDS
T02330
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
pacc
Cutibacterium acnes C1
Pathway
pacc00010
Glycolysis / Gluconeogenesis
pacc00020
Citrate cycle (TCA cycle)
pacc00620
Pyruvate metabolism
pacc00785
Lipoic acid metabolism
pacc01100
Metabolic pathways
pacc01110
Biosynthesis of secondary metabolites
pacc01120
Microbial metabolism in diverse environments
pacc01200
Carbon metabolism
pacc01210
2-Oxocarboxylic acid metabolism
Module
pacc_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pacc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
PAC1_05210 (aceE)
00020 Citrate cycle (TCA cycle)
PAC1_05210 (aceE)
00620 Pyruvate metabolism
PAC1_05210 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PAC1_05210 (aceE)
Enzymes [BR:
pacc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
PAC1_05210 (aceE)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
DUF2470
Motif
Other DBs
NCBI-ProteinID:
AFU40797
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All DBs
Position
1076120..1078873
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AA seq
917 aa
AA seq
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MIPREERGPVLNGLPTTLPDVDPEETQEWIESLDKMVETDGPNRARIVLLKMLERARSHS
RLGLSALTSTDYINTIAAEDEEEYPGDAEIERNIRRLLRWNSAITVHRAQRPGIGVGGHI
STYASAVTLYEVGQNHFWRGQDAPGGGDQVFFQGHAAPGMYARAFLEGRLSEDDLDGFRQ
EKSKAGHGLPSYPHPRMLPDFWQFPTVSMGLGPMDSIYQASMNKYLTNRGVKDCADQHVW
AFLGDGEMDEPESRGFLQVAANEELDNLTFVINCNLQRLDGPVRGNGKIVQELEAVFRGA
GWNVIKVIWGSGWDPLLQADRDGALVDIMNNTRDGDYQTFKANDGAYVREHFFGRDPRTA
KMVDKWTDEQIWALRRGGHDYRKIYNAYKAATQFKGAPTVVLACTIKGYDLGTHFAGRNA
THQMKKLALDDLKQFRDRLEIPISDKVLEADPYRAPYFHPGADDERIQYLMERRRALGGF
VPERRTRHTPLPIPAQKAFDGVKRGSGKQEVATTMAFVRLLKDLMRDKNFAPHVVPIIPD
EARTFGMDSFFPTIKIYNPHGQNYTPVDHELMLSYREAKNGQIIHTGINEAGSAAAFIAA
GSAYSTQGVPMVPIYLFYSMFGFQRTGDSFWAAGDQMTRGFIIGATAGRTTLTGEGTQHM
DGHSPVLAATNPAVISYDPAYSYEISHIVQAGLEHMYGENAEDVMYYLTVYNEPIVQPAE
PEGVDAEGIVKGMYLLSKGSFEGVGEDARRVQLLASGVAVPWAIEAQQLLKGDFGVVADV
WSVTSWNNLRRDAMEAEEQTFLHPERGRRTPYITQCLADAPGPVVATTDYTRQVPDQIAQ
WVPGDYASLGADGFGFSDTRAAARRFFHIDGPSMTVRALQMLVERGEVPEDWPAKAAEKY
DLLNVNAGASGNAGGDA
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
gtgatcccacgcgaagaacgcggaccagtcctcaacggacttccgacaaccctgcctgac
gtcgatcccgaggagactcaggagtggatcgagtccctcgacaagatggtcgagactgat
ggtccgaatcgtgcccggatcgtgctgctcaagatgttggagcgggctcgtagccacagt
cgtctcgggctgtcagcgctcacctccaccgactacatcaacaccattgcagccgaggac
gaggaagaataccccggcgacgccgagatcgagcggaacatccgtcgtttgctgcgctgg
aattccgccattaccgtgcatcgcgcgcagcgtcccggtattggcgtcggcggtcatatc
tccacctatgcctctgccgtgaccctctacgaggtcggtcagaaccacttctggcgcggg
caggacgcccccggcggcggtgaccaagttttcttccaggggcacgccgcgcccggtatg
tacgctcgcgcgttcttggaggggcgtctcagcgaggacgatctcgatgggttccgtcag
gagaagtcgaaggccgggcatggtctaccctcttacccgcaccctcgcatgttgcccgac
ttctggcagttcccgacggtgtcgatgggtctgggcccgatggattccatttaccaggcg
tctatgaataagtacctcaccaatcgcggtgtcaaggactgcgcagatcagcacgtgtgg
gctttccttggcgacggtgagatggacgagccggagtcgcgcggattcctgcaggtcgct
gccaacgaggagctcgacaacctcaccttcgtcatcaactgcaacctgcagcgtctagac
gggccggtgcgtggcaacggcaagattgtccaggaacttgaggctgtcttccgtggtgct
ggctggaacgtcatcaaggtcatttggggatccggctgggacccgttgctgcaggcagac
cgtgacggtgccctcgttgatatcatgaacaacacccgtgatggcgactaccaaaccttt
aaggccaacgacggcgcctatgtccgcgagcacttctttggccgcgacccgcgcactgcc
aagatggtcgacaagtggactgacgaacagatttgggcgttacgccgtggcggtcacgac
taccgcaagatttacaacgcctacaaggcggctacgcagttcaagggagcgccgaccgtg
gtgcttgcctgcactattaaaggttacgatcttggtactcactttgcgggccgcaacgct
acccaccagatgaagaagctggcccttgacgacctcaagcagttccgcgatcgtctcgaa
attccgatttcggacaaggtgctggaggccgacccctaccgtgctccctacttccatccc
ggagccgatgacgagcgcatccagtacctcatggagcgtcgtcgtgctctcggcggtttc
gtgccggagcgccgtacgaggcacacgccactacccatcccggcgcagaaggccttcgat
ggtgtcaagcgtgggtcgggcaaacaggaggtcgccaccacgatggccttcgtgcgtctg
ctcaaggaccttatgcgcgacaagaatttcgctccgcacgtcgtcccgatcattcctgac
gaggcccgtacctttggcatggactcgttcttcccgacgatcaagatctacaatcctcac
ggccagaactacacccctgtcgaccacgagctcatgctcagctaccgcgaggccaagaac
gggcagatcattcacactggcatcaatgaggctggttcggcggctgctttcattgccgca
ggctcggcatactccactcagggcgtgccgatggtgccgatctacctgttctactcgatg
ttcgggttccagcgtaccggtgattctttctgggcagctggtgatcagatgacgagggga
ttcattattggcgccactgccggacgcaccacgctgaccggtgagggcacccagcacatg
gatggccattcgccggttctggctgcgacgaacccagctgtcatctcctacgatccggct
tattcttacgagatctcccacattgttcaggcaggtctggagcacatgtacggcgagaac
gccgaagacgtcatgtactacctgacggtgtacaacgagccgatcgtccagccggctgag
ccagagggcgttgacgccgagggcatcgtcaagggcatgtacctgctctcgaagggctcc
tttgagggcgtcggcgaggatgcccgccgcgttcagctgctggcctccggcgtcgccgtg
ccgtgggccattgaggctcagcagctccttaagggtgactttggcgttgttgccgacgtg
tggtcggtgacgtcgtggaacaacctacgtcgtgacgctatggaggccgaggaacagact
ttcctacaccccgaacggggcaggcgcaccccgtatatcacccaatgcctggccgacgcc
cctggtccagtcgttgcgaccaccgattacacgcgtcaggtgcccgatcagatcgcccag
tgggtgccgggggattatgcctccttaggtgctgacggattcgggttctccgacacccgt
gcggcagcgcgccgattcttccacatcgatggaccgtccatgacagtgcgtgccctccag
atgctcgtcgagcgtggtgaggttcccgaggactggcctgccaaggctgccgagaagtac
gacctcctcaacgtcaacgcgggggcgtccggtaacgctggtggcgacgcctga
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