Cutibacterium acnes HL096PA1: PAGK_0894
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Entry
PAGK_0894 CDS
T02638
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
pach
Cutibacterium acnes HL096PA1
Pathway
pach00020
Citrate cycle (TCA cycle)
pach00630
Glyoxylate and dicarboxylate metabolism
pach00785
Lipoic acid metabolism
pach01100
Metabolic pathways
pach01110
Biosynthesis of secondary metabolites
pach01120
Microbial metabolism in diverse environments
pach01200
Carbon metabolism
pach01210
2-Oxocarboxylic acid metabolism
Module
pach_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pach_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pach00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
PAGK_0894
00630 Glyoxylate and dicarboxylate metabolism
PAGK_0894
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PAGK_0894
Enzymes [BR:
pach01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
PAGK_0894
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
PAGK_0894
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
PAGK_0894
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
PAGK_0894
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AGJ79738
LinkDB
All DBs
Position
complement(1006314..1010021)
Genome browser
AA seq
1235 aa
AA seq
DB search
MSPAPHDKSNNSPDFGANDWLIEEMRDQYQSDPNSVDPAWATFFRKEAVESTDSVTKSAA
KDVPGASAPKPATKPQPVPAAKPAPITAPKPQKQPPRPPMSADAPRHSAKLETVEPTVTK
MKGAPMRTAKNMDQSLTMPTATTVRNVPMQLVIEQRTMINSFLKKAKGGKVSFTHILAYA
MVQALKTVPAMNNAYAEIDGKPHLIENHQINLGMAIDVVASDGSRKLVVPAIKGAEQMDF
LDFWRAYEEIVRKGRTNELTVDDFKGVTASLTNPGGFGTNHSIARLMPGQGMILGVGSID
YPAAYQGNSPTRIAELGISKVTTLTSTYDHRIIQGAQSGEFLRRMHQLLLGADRFYEDIF
ESLRIPYAPVQWASDRLANRADQVGKQARVIELIDAWRRFGHLSADLDPIEYRPRFHRDL
MLNSHGLTLWDFDRTFPIANFAGQRRATMSLREILTILRDSYASKMGIEYMHIADYEQRK
WFQDRFEKEHQPLSRKMHLQILDQLNEAEIFETFLQTKFVGQKRFSLEGGESAIVLLAAL
CNRAADDGLNEVCIGMPHRGRLNVLANIIGKSYGQIFREFEGNAEPVNSQGSGDVKYHLG
DEGQFTAASGNTIKASVAANPSHLEAVDPVLEGICRAKLDALGNPEGFPVLPILMHGDAA
FAGQGVVYETLQMSQLGGYRTGGTIHVIVNNQVGFTTSPRDGRSSTYCTDVAKAVGAPVL
HVNGDDPASVVHAARIAYEYRQTFHRDVVVDVVCYRRRGHNEGDDPSFTQPHMYGLIAEK
RSTRKLYTESLIGRGDITTEDAEAVMTKFRSRLETVFKEVREATSTPEPYSGVPDYPVKH
SGLHQTKVEPDTMEAVARAHENLPESFNAHPKVAPQMTRRAKHIREGGIDWATGEMIALG
SLLRDGVHVRLAGQDSRRGTFSQRFAALVDHETGEFYVPVNHLGGEQAHLDVFDSPLNEY
AAMGFEYGYSVARPDSLVLWEAQFGDFTNGAQTIIDEFIASAGSKWGQKSGVVLLLPHGY
EGQGPDHSSARLERFLNLCSEDALAVCQPSTPASYSHLLRQHAYVNMHRPVVIATPKSML
RNKMATSDPEDFTTGRWRPVLPDPSITDPTAVTRIILCSGKARWELVKQRKAASLDGQLA
IIPMERLYPLPVDELAEVLAPYTNVTDVRWVQEEPENQGAWYYMLTHLPQAMSEKLPGFF
DGLVGITRPPSSAPSVGQHSVHIREEQELLEKAMA
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
gtgagtcccgccccacacgacaagtccaacaactctcctgattttggagccaacgactgg
ctcatcgaagagatgcgtgaccagtatcagagtgatccgaattcggtcgatccggcctgg
gctacgttctttcgcaaggaggcagtcgagtccaccgactcggtgactaaatctgccgct
aaggatgtcccaggcgcgtcggcccccaagcctgcgacgaagccgcagcctgttcctgct
gcgaaacccgcgcccatcacagccccgaagccccaaaagcagcctccgcgtcctccaatg
tccgcagacgcaccgcgacatagcgccaagctcgagactgttgagccgacggtaacgaaa
atgaagggtgcgccgatgcgcaccgccaagaatatggatcagtcgctaaccatgccgacg
gccacgacggtacgtaacgtaccgatgcaattggtcatcgaacagcgcaccatgatcaac
tccttccttaagaaggccaaaggcggcaaggtttccttcacccatatcctggcttatgcc
atggtccaggccctcaaaacggtgcccgccatgaacaatgcatatgccgagattgacggt
aaaccgcacctcatcgaaaaccatcagatcaacctcggcatggccatcgacgtcgttgcc
tcggatggatcgcgcaagctggttgtgcctgctatcaagggcgccgagcagatggacttc
cttgatttctggcgagcttatgaggagatcgtccggaaggggcgcactaatgagctgacc
gtcgacgatttcaagggggttaccgcctccctgacgaacccgggtggctttggcaccaat
cactccatcgctcgcctcatgcctggccagggcatgatcctcggggttggatcgattgac
tatcccgccgcctatcagggcaactcccctactcgaatagcggagttgggtatctccaag
gtgacgacgctcacctcgacctatgaccatcgcatcatccagggtgctcagtccggagaa
ttcctgcgccgcatgcatcagttgttgctgggagctgaccgcttctatgaggacatcttc
gagtcactgcgcatcccctacgccccggttcagtgggcaagtgaccgtcttgctaatcgc
gctgatcaggtaggaaagcaagctcgcgtcatcgaactcatcgatgcgtggcgtcgtttc
ggacacctatcggctgatctcgatcccatcgagtaccggccgcggttccaccgcgacctc
atgctcaacagccacgggctgacgctgtgggacttcgaccgtaccttcccgatcgcgaac
ttcgctggtcagcgccgcgccacgatgtccttgcgcgagattctcacgatcttgcgtgac
tcgtacgcctcgaagatgggcatcgagtacatgcacatcgccgactatgagcagcgcaag
tggttccaggaccgtttcgagaaggagcatcagccgctctctcggaagatgcatttgcag
atcctcgaccaactcaacgaggccgagatctttgagaccttcttgcagaccaagttcgtc
ggtcagaagcgtttcagcctggaaggcggcgagtccgccatcgtcttgctggcagcccta
tgcaatcgcgcagctgacgatggtctcaacgaagtctgcatcggcatgccgcaccgtggc
cgtctcaatgtgctagccaacatcatcgggaaatcctacggacagatcttccgtgaattc
gagggcaatgccgagccggtgaattctcaggggtccggtgacgtcaagtaccacctcggt
gatgaaggccagttcaccgcagcctcgggtaacaccatcaaggcatctgtcgccgctaat
cccagccacctcgaggcagtcgatccggttctcgaaggtatctgccgtgccaagcttgac
gccctcggcaaccccgaaggtttcccggtactgcccattctcatgcacggtgacgctgcg
ttcgcgggtcagggtgtcgtctacgaaaccctgcagatgagccagcttgggggctaccgc
actggcggcaccattcacgtcatcgtcaacaatcaggttggctttaccacttccccgcgc
gacggtcgttcctcaacctactgcaccgatgtcgctaaggctgttggcgcaccggtcctc
cacgtcaacggagatgacccggcatcggtggtccacgcggctcgtatcgcctacgagtat
cgccagaccttccatcgcgatgtcgtcgttgacgtggtgtgctatcgccggcgcggccat
aacgagggtgacgatccgagcttcacacaaccgcacatgtacggcctcatcgctgaaaag
cgctcgacccgcaagctctacaccgagagcctcatcggtcgtggcgatatcactaccgag
gacgccgaggctgtgatgacaaagttccgctctcgtctggagacagtgttcaaggaggtt
cgcgaagccacctcgacgcctgagccctacagcggtgtgccagactacccggtcaagcac
agtggcctgcaccagaccaaggtcgagcctgacacaatggaggccgtcgccagggctcat
gagaatctgccagaaagcttcaatgctcaccccaaggtcgccccacagatgacacggcgc
gccaagcatatccgtgagggcggtattgactgggccaccggagagatgatcgcattgggc
tcccttctgcgtgatggcgtacacgtccgtctagccggtcaggacagccgccgcggcacc
ttctcccagcgttttgcggcgctggtagatcacgaaaccggtgagttctacgtcccggtt
aaccacctcggaggcgaacaggcgcacctcgacgtcttcgattctccgcttaacgagtac
gcagcgatgggatttgagtacggctactctgtcgcccgtccggattctctggtgctgtgg
gaagcccaattcggcgatttcaccaacggtgctcagacgatcattgatgagttcatcgcc
tcggctggctccaagtggggtcagaagtcgggagtcgtgctgctgctgccgcacggttac
gaaggtcaggggcctgatcactcatcggcccgtctggagcgcttcctcaatctatgcagt
gaagacgctttggccgtctgccagccctcgaccccggcaagctacagccatttattgcgt
cagcacgcgtacgtcaatatgcatcgtccagtcgttatcgcaacgccgaaatcgatgctg
cgcaacaagatggcgacctcggatcccgaagacttcaccaccggtaggtggcgtcctgtt
ctacccgacccatcgatcaccgacccgacggccgttacgaggattatcttgtgctctggc
aaggcgcggtgggagctagtcaagcaacgtaaggccgccagtcttgacggacagctcgcc
atcatcccgatggagcgtctctacccgctaccagtcgacgagttggctgaggttcttgcg
ccttacaccaacgtcacggatgtccgctgggtccaagaagagccagagaaccagggcgcc
tggtactacatgctgacccacctgccccaggccatgtcggagaagttgccaggattcttt
gatgggttagtcggcatcacccgcccaccgtcctcagctccgtcggtgggacagcacagc
gtccacatccgtgaagagcaggagttactcgagaaggctatggcctga
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