Arcobacter acticola: AACT_0190
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Entry
AACT_0190 CDS
T06605
Symbol
metH
Name
(GenBank) cobalamin-dependent methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
paco
Arcobacter acticola
Pathway
paco00270
Cysteine and methionine metabolism
paco00450
Selenocompound metabolism
paco00670
One carbon pool by folate
paco01100
Metabolic pathways
paco01110
Biosynthesis of secondary metabolites
paco01230
Biosynthesis of amino acids
paco04981
Folate transport and metabolism
Module
paco_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
paco00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
AACT_0190 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
AACT_0190 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
AACT_0190 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
AACT_0190 (metH)
04980 Cobalamin transport and metabolism
AACT_0190 (metH)
Enzymes [BR:
paco01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
AACT_0190 (metH)
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QKE27422
UniProt:
A0A6M8EBP0
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All DBs
Position
178994..182470
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AA seq
1158 aa
AA seq
DB search
MLETIKDLIKNRVLVIDGAMGTQLQLADIKKEEWIYEGADLEGCNELLNLTAPHILETIH
DAYAAAGADLISTNTFGSMPWVLDEYDIGHTSYELSKLGAELVKKSCVKYSTPDKPRYVL
GSIGPGTKLPSLNHIKYDEMYEGYKVMASGLADGGCDIFLLETCQDPLQIKAALHALNDT
APQIPIMVSVTIELSGTMLIGTDALTIAAIMAPFNILSLGFNCGTGPKQVHKHVKTLSEV
CRFPISVHANAGLPQNRGGKTYYPMQPTEFVELQKEFLNINGVSFLGGCCGTTPEHIEAL
AKAIEGVTPLKPCGFLKASLASLFGTVPLKQEPAPLLIGERSNATGSKAFRELLKANDYE
GTLSVGQQQVRAGAHVIDVSVGFAGRDERFDMDAVTALYSQKVALPLMPDSTQIYALEAA
LKQIGGRAIINSVNLEDGEEKFDAVCKLAKKFGAALVCLVIDEVGMAKTKEDKIRIAERI
FDLCVNRHGFDPHDLVFDMLTFTIGSGDDEYRTAGVETMEAIREFQILHPEVGTTLGLSN
ISFGLDTKARIYLNSIYLDHCVRAGLTSAIVNVKHIIPLNKISEEDRKACDNLIFNNHEN
GDPLFAFIEHFSNVEAQEEQTDEEYQNMPPLEKVQKLLLDGDKDRLLPLVDELRHTVNPE
IIVNEWLIDGMKIIGELFGSGQMQLPFVLQSAETMKATVDALNPYLPKEEKDSETTLILG
TVKGDVHDVGKNLVDIILSNNGFKVVNIGIKAGLDTFIDKLQEHKAHAIGMSGLLVKSTA
VMKENLEELQRLGIKVPVLLGGAALTKNFIDEYCRPYYDGPIFYCRDAFDGVVSMQRIEK
GDENNTALAADLIKVIDTSDRVEEEAVEIPPYEEIPLPAANTFTFPPLWDRVAKSGAKLD
KELIFKWINHRVLFRQRWGYKRGKQDSAKFLQYEKDVVEPTYEALKAELIDKDIFDPIAI
YAYYPCISHDNKLYIFDKKYLFNTLEEAKNVPPLEEAIKVLEFPRQKRKPFRCIADFFAN
DRLDVVAFTLASAGLKISDYERSIYDKGEFTKYYQVHGLGVELAEALAEVLHKQIRLDLD
IVPKEGHTLNDVQMKQYVGCRYSPGYAACPDLAMNRDIFDLLKPEEFGIELSETFQMHPE
QTTCAIVVTHKEANYYNI
NT seq
3477 nt
NT seq
+upstream
nt +downstream
nt
atgttagaaacaatcaaagatttaataaaaaatagagttttagtaatagatggagctatg
ggaacacagcttcaactagctgatataaaaaaagaagagtggatttatgaaggtgctgat
ttagaagggtgtaatgaacttctaaatcttacagctcctcatatccttgaaactattcat
gatgcttatgcagcagccggtgctgatttaataagtacaaatacatttggttcgatgcca
tgggttttagatgaatatgatattggtcatacctcttatgaactttcaaagttaggggca
gagcttgtaaagaaatcttgtgttaaatatagcacaccagataaaccaagatatgtatta
ggttctattggacctggaactaaacttccatcattaaatcatatcaaatatgatgaaatg
tatgaaggttacaaagttatggcttctggacttgcagatggtggatgtgatattttctta
cttgaaacatgtcaagacccacttcaaataaaagcagcacttcatgctttaaatgacaca
gcaccacaaattcctataatggtatctgttactattgagttaagtggtacgatgttaatt
ggaactgatgctttaacaattgctgctattatggctccatttaatattttatctttaggg
tttaactgtggaactggaccaaaacaagttcataaacatgttaaaactttaagtgaagtt
tgtagattcccaatatcagttcacgcaaatgcgggacttcctcaaaatagaggtggaaaa
acttattatccaatgcaaccaactgagtttgtagaacttcaaaaagagtttttaaatatc
aatggtgtttcatttttaggtggttgttgtggaacaacacctgaacatattgaagcatta
gcaaaggctattgagggagtaacaccacttaaaccttgtggatttttaaaagcttcatta
gcttcactttttggaacagttcctttaaaacaagaaccagctccacttttaattggtgag
cgttcaaatgcaacaggaagtaaggcttttagagaattattaaaagcaaatgattatgag
ggaacacttagcgttggacaacaacaagtaagagctggtgctcacgtaattgatgtttct
gtaggattcgcaggtagggatgaaagatttgatatggatgcggttaccgctctttattct
caaaaagttgcacttcctttaatgccagactctactcagatttatgccctagaagcagca
ctaaaacaaataggtggaagagctattataaactctgttaaccttgaagatggtgaagaa
aaatttgatgctgtttgtaaattggctaaaaaatttggagcagcacttgtttgtttggtt
attgatgaagttggaatggcaaaaacaaaagaagataaaatcagaatagctgaaagaata
tttgacttatgtgtaaacagacatggttttgacccacatgatttagtatttgatatgctt
acatttacaattggatcaggtgatgatgagtatagaacagctggtgttgaaacaatggaa
gcaattagagaattccagattttacatccagaagttggaactactctaggactttcaaat
atctcttttggtcttgatacaaaagctagaatttatcttaattcgatttatttagatcat
tgtgtaagagctggtctaacatctgctattgtaaatgttaaacatattattccactaaat
aaaataagtgaagaagatagaaaggcttgtgataatttaatatttaataatcatgaaaat
ggtgacccattatttgcctttattgaacacttctcaaatgtagaagcacaagaagaacaa
acagatgaagagtatcaaaatatgcctcctcttgaaaaagtacaaaaacttttacttgat
ggggataaagatagacttcttcctttggtagatgagttaagacacactgtaaaccctgaa
attattgtaaatgaatggttaattgatggtatgaaaattattggtgaattatttggaagt
ggacagatgcagttaccatttgtacttcaaagtgctgaaactatgaaagcaactgttgat
gcattaaatccatacttaccaaaagaggaaaaagatagtgaaacaacactgattttagga
actgtgaaaggtgatgttcatgatgtcggtaaaaatctagttgatattattctaagtaat
aatggatttaaagttgtaaatattggtataaaagctggtcttgatacttttattgacaaa
cttcaagagcataaagcacacgcaattggaatgagtggattacttgtaaaatcaacagct
gttatgaaagaaaacttagaagaacttcaaagactaggaatcaaagttcctgtactttta
ggtggtgcagcacttactaaaaactttattgatgagtattgccgaccttattatgatggt
cctattttttattgtagagatgcttttgatggtgttgtttctatgcaaagaattgaaaag
ggtgatgaaaataatacagcccttgcagctgatttaataaaagtaattgatacaagtgac
agagttgaagaagaagcagtagaaattcctccttatgaagagattccacttcctgcagca
aatacatttactttccctccactttgggatagagttgcaaaaagtggagcaaaactagat
aaagaacttatttttaaatggataaatcatagggttttatttagacaaagatggggatac
aaaagaggaaagcaagattcagctaaattcttacaatatgaaaaagatgtagttgaacca
acttatgaagctttaaaagctgaattaattgataaagatatttttgacccaattgctatt
tatgcttattatccttgtatctcccatgataataaactttatatctttgataaaaaatat
ctgtttaatacacttgaagaagcaaaaaatgtaccaccattagaagaagctataaaggta
ttagaattccctagacaaaaaagaaaaccgtttagatgtatagctgatttctttgcaaat
gatagacttgatgtagttgcctttacacttgcaagtgctggacttaaaataagtgattat
gaaagaagtatttatgataagggtgaatttacaaaatactatcaagttcacggtcttgga
gttgagttagctgaagctttagctgaggttttacacaaacaaataagacttgatttagat
atagttccaaaagagggacatactttaaatgatgttcaaatgaaacaatatgtaggttgt
agatattcacctggatatgcagcttgtcctgatttagcgatgaatagagatatttttgat
ttattaaaaccagaagagtttggaatagagttatctgaaacatttcaaatgcatcctgaa
caaacaacttgcgctattgtggttactcacaaagaagcaaactactataatatttaa
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