Cutibacterium acnes subsp. defendens ATCC 11828: TIIST44_08315
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Entry
TIIST44_08315 CDS
T01972
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
pad
Cutibacterium acnes subsp. defendens ATCC 11828
Pathway
pad00020
Citrate cycle (TCA cycle)
pad00630
Glyoxylate and dicarboxylate metabolism
pad00785
Lipoic acid metabolism
pad01100
Metabolic pathways
pad01110
Biosynthesis of secondary metabolites
pad01120
Microbial metabolism in diverse environments
pad01200
Carbon metabolism
pad01210
2-Oxocarboxylic acid metabolism
Module
pad_M00009
Citrate cycle (TCA cycle, Krebs cycle)
pad_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
pad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
TIIST44_08315 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
TIIST44_08315 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TIIST44_08315 (kgd)
Enzymes [BR:
pad01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
TIIST44_08315 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
TIIST44_08315 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
TIIST44_08315 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
TIIST44_08315 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AER06127
LinkDB
All DBs
Position
complement(1758984..1762691)
Genome browser
AA seq
1235 aa
AA seq
DB search
MSPAPHDKSNNSPDFGANNWLIEEMRDQYQSDPNSVDPAWATFFRKEAVESTDSVTKSAA
KDVPGASAPKPATKPQPVPAAKPAPITAPKPQKQPPRPPMSADAPRHSAKLETVEPTVTK
MKGAPMRTAKNMDQSLTMPTATTVRDVPMQLVIEQRTMINSFLKKAKGGKVSFTHILAYA
MVQALKTVPAMNNAYAEIDGKPHLIENHQINLGMAIDVVASDGSRKLVVPAIKGAEQMDF
LDFWRAYEEIVRKGRTNELTVDDFKGVTASLTNPGGFGTNHSIARLMPGQGMILGVGSID
YPAAYQGNSPTRIAELGISKVTTLTSTYDHRIIQGAQSGEFLRRMHQLLLGADRFYEDIF
ESLRIPYAPVQWASDRLANRADQVGKQARVIELIDAWRRFGHLSADLDPIEYRPRFHHDL
MLNSHGLTLWDFDRTFPIANFAGQRRATMSLREILTILRDSYASKMGIEYMHIADYEQRK
WFQDRFEKEHQPLSRKMHLQILDQLNEAEIFETFLQTKFVGQKRFSLEGGESAIVLLAAL
CNRAADDGLNEVCIGMPHRGRLNVLANIIGKSYGQIFREFEGNAEPVNSQGSGDVKYHLG
DEGQFTAASGNTIKASVAANPSHLEAVDPVLEGICRAKLDALGNPEGFPVLPILMHGDAA
FAGQGVVYETLQMSQLGGYRTGGTIHVIVNNQVGFTTSPRDGRSSTYCTDVAKAVGAPVL
HVNGDDPASVVHAARIAYEYRQTFHRDVVVDVVCYRRRGHNEGDDPSFTQPHMYGLIAEK
RSTRKLYTESLIGRGDITTEDAEAVMTKFRSRLETVFKEVREATSTPEPYSGVPDYPVKH
SGLHQTKVEPDTMEAVARAHENLPESFNAHPKVAPQMTRRAKHIREGGIDWATGEMIALG
SLLRDGVHVRLAGQDSRRGTFSQRFAALVDHETGEFYVPVNHLGGEQAHLDVFDSPLNEY
AAMGFEYGYSVARPDSLVLWEAQFGDFTNGAQTIIDEFIASAGSKWGQKSGVVLLLPHGY
EGQGPDHSSARLERFLNLCSEDALAVCQPSTPASYSHLLRQHAYVNMHRPVVIATPKSML
RNKMATSDPEEFTTGRWRPVLPDPSITDPTAVTRIILCSGKVRWELVKQRKAASLDGQLA
IIPMERLYPLPVDELAEVLAPYTNVTDVRWVQEEPENQGAWYYMLTHLPQAMSEKLPGFF
DGLVGITRPPSSAPSVGQHSVHIREEQELLEKAMA
NT seq
3708 nt
NT seq
+upstream
nt +downstream
nt
gtgagtcccgccccacacgacaagtccaacaactctcctgattttggagccaacaactgg
ctcatcgaagagatgcgtgaccagtatcagagtgatccgaattcggtcgatccggcctgg
gctacgttctttcgcaaggaggcagtcgagtccaccgactcggtgactaaatctgccgct
aaggatgtcccaggcgcgtcggcccccaagcctgcgacgaagccgcagcctgttcctgct
gcgaaacctgcgcccatcacagccccgaagccccaaaagcagcctccgcgtcctcccatg
tccgcagacgcaccgcgacatagcgccaagctcgagactgttgagccgacggtaacgaaa
atgaagggtgcgccgatgcgcaccgccaagaatatggatcagtcgctaaccatgccgaca
gccacgacggtacgtgacgtaccgatgcaattggtcatcgagcagcgcaccatgatcaac
tccttccttaagaaggccaaaggcggcaaggtttccttcacccatatcctggcttatgcc
atggtccaggccctcaaaacggtgcccgccatgaacaatgcatatgccgagattgacggt
aaaccgcacctcatcgaaaaccatcagatcaacctcggcatggccatcgacgtcgttgcc
tcggatggatcgcgcaagctggttgtgcctgctatcaagggcgccgagcagatggacttc
cttgatttctggcgagcttacgaggagatcgtccgaaaggggcgcactaatgagctgacc
gtcgacgatttcaagggggttaccgcctccctgacgaacccgggtggctttggcaccaat
cactccatcgctcgcctcatgcctggccagggcatgatcctcggggttggatcgattgac
tatcccgccgcctaccagggcaactctcccactcgaatagcggagttgggtatctccaag
gtgacgacgctcacctctacctacgaccatcgcatcatccagggcgctcagtccggagaa
ttcctgcgacgcatgcatcagttgttgctgggagctgaccgcttctatgaggacatcttc
gagtcactgcgcatcccctacgccccggttcagtgggcaagtgaccgtcttgctaatcgc
gctgatcaggtaggaaagcaagctcgcgtcatcgaactcatcgatgcgtggcgtcgtttc
ggacatctatcggctgatctcgatcccatcgagtaccggccgcggttccaccacgacctc
atgctcaacagccacgggctgacgctgtgggacttcgaccgtaccttcccgatcgcgaac
ttcgctggtcagcgccgtgccacgatgtccttgcgcgagattctcacgatcttgcgtgac
tcgtacgcctcgaagatgggcatcgagtacatgcacatcgccgactatgagcagcgcaag
tggttccaggaccgtttcgagaaggagcatcagccgctctctcggaagatgcatttgcag
atcctcgaccaactcaacgaggccgagatcttcgagaccttcttgcagaccaagttcgtc
ggtcagaagcgtttcagcctggaaggcggcgagtccgccatcgtcttgctggcagcccta
tgcaatcgcgcagctgacgatggtctcaacgaagtctgcatcggcatgccgcaccgtggc
cgtctcaatgtgctagccaacatcatcgggaaatcctacggacagatcttccgtgaattc
gaaggcaatgccgagccggtgaattctcaggggtccggtgacgttaagtaccacctcggt
gatgaaggccagttcaccgcagcctcgggtaacaccatcaaggcatctgtcgccgccaat
cccagccacctcgaggcagtcgatccggttctcgaaggtatctgtcgtgccaagcttgac
gccctcggcaaccccgaaggtttcccggtactgcccattctcatgcacggtgacgctgca
ttcgcgggtcagggtgtcgtctacgaaaccctgcagatgagccagcttgggggctaccgc
actggcggcaccattcacgtcatcgtcaacaatcaggttggctttaccacttccccgcgc
gacggtcgttcctcaacctactgcaccgatgtcgctaaggctgttggcgcaccggtcctc
cacgtcaacggagacgacccggcatcggtggtccacgcggctcgtatcgcctacgagtac
cgccagaccttccatcgcgatgtcgtcgttgacgtggtgtgctatcgccggcgcggccat
aacgagggtgacgatccgagcttcacacagccgcacatgtacggcctcatcgctgaaaag
cgctcgacccgcaagctctacaccgagagcctcatcggtcgtggcgatattactaccgag
gacgccgaggctgtgatgacaaagttccgctctcgtctggagacagtgttcaaggaggtt
cgcgaggccacctcaacgcctgagccctatagcggtgtgccagactacccggtcaagcac
agtggcctgcaccagaccaaggtcgagcctgacacaatggaggctgtcgccagggctcat
gagaatctgccagaaagcttcaatgctcaccccaaggtcgccccacagatgacacggcgc
gccaagcatatccgtgagggcggtattgactgggccaccggagagatgatcgcattgggc
tcccttctgcgtgatggcgtacacgtccgtctagctggtcaggacagccgccgcggcacc
ttctcccagcgttttgcggcgctggtagatcacgagaccggtgagttctacgtcccggtt
aaccacctcggaggtgaacaggcgcacctcgacgtcttcgattctccgcttaacgagtac
gcagcgatgggatttgagtacggctactctgttgcccgtccggattctctggtgttgtgg
gaagcccaattcggcgatttcaccaacggtgctcagacgatcatcgatgagttcatcgcc
tcggctggctccaagtggggtcagaagtcgggagtcgtgctgctgctgccgcacggttac
gaaggtcaggggcctgatcactcgtcggcccgtctggagcgcttcctcaatctatgcagt
gaagacgctttggccgtctgccagccctcgaccccggcaagctacagccatttattgcgt
cagcacgcgtacgtcaatatgcatcgtccagtcgttatcgcaacgccgaaatcgatgctg
cgcaacaagatggcgacctcggatcccgaagagttcaccaccggtaggtggcgtcctgtt
ctacccgacccatcgatcaccgatccgacggccgttacgaggattatcttgtgctctggc
aaggtgcggtgggagctggtcaagcaacgtaaggccgccagtcttgacggacagctcgcc
atcatcccgatggagcgtctctacccgctaccagtcgacgagttggctgaggttctcgcg
ccgtacaccaacgtcacggatgttcgctgggtccaagaagagccagagaaccagggcgcc
tggtactacatgctgacccacctgccccaggccatgtcggagaagctgccaggattcttt
gatgggttagtcggcatcacccgcccaccgtcttcagctccttcggtgggacagcatagc
gtccacatccgtgaagagcaggagttgctcgagaaggctatggcctga
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