KEGG   Pseudomonas aeruginosa PAO1: PA0350
Entry
PA0350            CDS       T00035                                 
Symbol
folA
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
pae  Pseudomonas aeruginosa PAO1
Pathway
pae00670  One carbon pool by folate
pae00790  Folate biosynthesis
pae01100  Metabolic pathways
pae01240  Biosynthesis of cofactors
pae04981  Folate transport and metabolism
Module
pae_M00126  Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:pae00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    PA0350 (folA)
   00670 One carbon pool by folate
    PA0350 (folA)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    PA0350 (folA)
Enzymes [BR:pae01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     PA0350 (folA)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 879233
NCBI-ProteinID: NP_249041
UniProt: Q9I6E3
LinkDB
Position
393308..393814
AA seq 168 aa
MARPLAMIAALGENRAIGIDNRLPWRLPADLKHFKAMTLGKPVIMGRKTWDSLGRPLPGR
LNLVVSRQAGLALEGAEVFASLDAALARAEAWAQAEDADELMLIGGAQLYAEALPRAARL
YLTRVGLAPEGDAFFPEIDGAAWRLASSIEHAAADDAPAYAFEVWERR
NT seq 507 nt   +upstreamnt  +downstreamnt
atggcacgaccgctggcgatgatcgccgcccttggcgagaaccgcgcgatcggcatcgac
aaccgcctgccctggcgcctgccggccgacctcaagcatttcaaggcgatgaccctcggc
aagccggtgatcatggggcgcaagacctgggactcgctgggtcggccgctgccgggccgg
ctaaacctggtggtcagccgccaggccggcctggcactggagggtgcggaagtgttcgcc
agcctggacgccgcgctggcgcgcgccgaggcgtgggcgcaggcggaggacgccgacgaa
ctgatgctgatcggcggcgcccagctctatgccgaggccttgccgcgcgccgcgcgtctc
tacctgacccgggttggcctggcgccggagggcgacgcctttttccccgagatcgatggt
gcggcctggcgcctggcgtcgagcatcgaacacgccgcggctgacgatgcgcctgcctac
gccttcgaggtatgggagcgccgctga

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