Pseudomonas aeruginosa c7447m: M802_5186
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Entry
M802_5186 CDS
T03098
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
paec
Pseudomonas aeruginosa c7447m
Pathway
paec00010
Glycolysis / Gluconeogenesis
paec00020
Citrate cycle (TCA cycle)
paec00620
Pyruvate metabolism
paec00785
Lipoic acid metabolism
paec01100
Metabolic pathways
paec01110
Biosynthesis of secondary metabolites
paec01120
Microbial metabolism in diverse environments
paec01200
Carbon metabolism
paec01210
2-Oxocarboxylic acid metabolism
Module
paec_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
paec00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
M802_5186 (aceE)
00020 Citrate cycle (TCA cycle)
M802_5186 (aceE)
00620 Pyruvate metabolism
M802_5186 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
M802_5186 (aceE)
Enzymes [BR:
paec01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
M802_5186 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
Motif
Other DBs
NCBI-ProteinID:
AGV63236
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Position
5633958..5636606
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AA seq
882 aa
AA seq
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MQDLDPVETQEWLDALESVLDREGEDRAHYLMTRMGELASRSGTQLPYAITTPYRNTIPV
THEARMPGDLFMERRIRSLVRWNALAMVMRANKHDPDLGGHISTFASSATLYDIGFNYFF
QAPTDEHGGDLVFFQGHASPGVYARAFLEGRISEEQLENFRQEVDGNGLSSYPHPWLMPD
FWQFPTVSMGLGPIQAIYQARFMKYLESRGFIPAGKQKVWCFMGDGECDEPESLGAISLA
GREKLDNLIFVINCNLQRLDGPVRGNAKIIQELEGVFRGAEWNVNKVIWGRFWDPLFAKD
TAGLLQQRMDEVIDGEYQNYKAKDGAYVREHFFGARPELLEMVKDLSDEEIWKLNRGGHD
PYKVYAAYHQAVNHKGQPTVILAKTIKGYGTGSGEAKNIAHNVKKVDVDSLRAFRDKFDI
PVKDADLEKLPFYKPEEGSAEAKYLAERRAALGGFMPVRRQKSMSVPVPPLETLKAMLDG
SGDREISTTMAFVRIISQLVKDKELGPRIVPIVPDEARTFGMEGMFRQLGIYSSVGQLYE
PVDKDQVMFYREDKKGQILEEGINEAGAMSSWIAAGTSYSTHNQPMLPFYIFYSMFGFQR
IGDLAWAAGDSRAHGFLIGGTAGRTTLNGEGLQHEDGHSHLLASTIPNCRTYDPTYAYEL
AVIIREGSRQMIEEQQDIFYYITVMNENYVQPAMPKGAEEGIIKGMYLLEEDKKEAAHHV
QLLGSGTILREVEEAAKLLRNDFGIGADVWSVPSFNELRRDGLAVERWNRLHPGQKPKQS
YVEECLGGRRGPVIASTDYMKLYAEQIRQWVPSKEYKVLGTDGFGRSDSRKKLRNFFEVD
RHWVVLAALEALADRGDIEPKVVAEAIAKYGIDPEKRNPLDC
NT seq
2649 nt
NT seq
+upstream
nt +downstream
nt
atgcaagacctcgatcccgtcgaaacccaggaatggctggacgccctggagtccgtactc
gaccgcgaaggtgaagaccgcgctcattacctgatgacccgcatgggcgagctggccagc
cgtagcggcacccaactgccctacgcgatcaccacgccctatcgcaacaccattccggta
acccacgaagcacgcatgcccggcgacctgttcatggaacgccggatccgctccctggtg
cgctggaacgccctggcgatggtgatgcgggcgaacaagcacgacccggacctgggcggc
cacatctccaccttcgcctcctcggcgaccctctacgacatcggcttcaactatttcttc
caggctcccaccgacgaacacggcggcgacctggtgttcttccagggccacgcgtccccc
ggcgtctacgcccgggccttcctcgaaggccgcatcagcgaggaacaactggagaacttc
cgccaggaagtggacggcaacggcctgtcctcctatccgcacccctggctgatgccagac
ttctggcagttccccaccgtatccatgggccttggcccgatccaggcgatctaccaggca
cgtttcatgaagtacctggaaagccgcggcttcatccccgccggcaagcagaaggtctgg
tgcttcatgggcgacggcgagtgcgacgagccggaatccctcggcgcgatctccctggcc
ggccgcgagaaactcgacaacctgatcttcgtcatcaactgcaacctgcagcgcctcgac
ggcccggtccgcggcaacgccaagatcatccaggaactggaaggcgtgttccgcggcgcc
gagtggaacgtcaacaaggtcatctggggtcgcttctgggacccgctgttcgccaaggac
accgccggcctgctgcagcagcgcatggacgaggtcatcgacggcgaataccagaactac
aaggcgaaagacggcgcctacgtgcgcgagcacttcttcggcgcgcgtccggaactgctg
gaaatggtcaaggacctttccgacgaggaaatctggaagctcaaccgcggcggccacgac
ccctacaaggtctatgcggcctaccaccaggcggtcaaccacaagggccagccgaccgtc
atcctggccaagaccatcaagggctacggcaccggcagcggcgaagcgaagaacatcgcg
cacaacgtgaagaaggtcgacgtcgacagcctgcgcgcgttccgcgacaagttcgacatc
ccggtcaaggacgccgacctggagaagctgccgttctacaagcctgaagaaggcagcgcc
gaggccaagtacctggccgagcgccgcgccgcgctgggcggcttcatgccggtgcgccgg
cagaagagcatgagcgtgccggttccgccgctggaaaccctgaaggccatgctcgacggc
tccggcgatcgcgagatatccaccaccatggccttcgtgcggatcatctcgcagctggtc
aaggacaaggaactcggcccgcgcatcgtcccgatcgtcccggacgaggcccgtaccttc
ggcatggaaggcatgttccgccagctcggcatctactcctcggtcggccagctctacgag
ccggtggacaaggaccaggtgatgttctaccgcgaggacaagaagggccagatcctcgag
gaaggcatcaacgaggccggcgccatgtccagctggattgccgccggtacctcctacagc
acccacaaccagccgatgctgccgttctacatcttctattcgatgttcggcttccagcgc
atcggcgacctggcctgggccgccggcgacagccgcgcgcacggcttcctgatcggcggc
accgccggtcgcaccacgctgaacggcgaaggcctgcagcacgaggacggccacagccac
ctgctggcctcgaccatcccgaactgccgcacctacgatccgacctacgcctacgaactg
gcggtgatcatccgcgaaggctcgcggcagatgatcgaagagcagcaggacatcttctac
tacatcaccgtgatgaacgagaactacgtccagccggccatgccgaagggcgcagaggaa
ggcatcatcaagggcatgtacctcctcgaggaggacaagaaggaagccgctcaccacgtg
caactgctgggctccggcaccatcctgcgcgaagtcgaggaagcggccaagctgctgcgc
aacgacttcggcatcggcgccgacgtctggagcgtgccgagcttcaacgaactgcgtcgc
gacggccttgccgtcgagcgctggaaccgcctgcatccgggccagaagccgaagcagagc
tacgtcgaggagtgcctgggcggccgtcgcggcccggtgatcgcctccaccgactacatg
aagctctatgccgagcagatccgccagtgggttccctccaaggagtacaaggtgctcggc
accgacggcttcggccgtagcgacagccgcaagaagctgcgcaacttcttcgaagtggat
cgtcactgggtggtgctggccgcgctcgaagcgctggccgatcgcggcgatatcgagccg
aaagtggtggccgaggccatcgccaagtacggtatcgatccggagaagcgcaacccgctg
gattgctaa
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