KEGG   Pseudomonas aeruginosa PAO1-VE13: N297_1900
Entry
N297_1900         CDS       T03097                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
paev  Pseudomonas aeruginosa PAO1-VE13
Pathway
paev00270  Cysteine and methionine metabolism
paev00450  Selenocompound metabolism
paev00670  One carbon pool by folate
paev01100  Metabolic pathways
paev01110  Biosynthesis of secondary metabolites
paev01230  Biosynthesis of amino acids
paev04980  Cobalamin transport and metabolism
paev04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:paev00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    N297_1900 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    N297_1900 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    N297_1900 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    N297_1900 (metH)
   04980 Cobalamin transport and metabolism
    N297_1900 (metH)
Enzymes [BR:paev01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     N297_1900 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: AGY74235
LinkDB
Position
complement(1999884..2003588)
AA seq 1234 aa
MSSPLTDRSARLQALQHALRERILILDGGMGTMIQSYKLEEADYRGERFADWPSDVKGNN
DLLLLSRPDVIQAIEKAYLDAGADILETNTFNATQVSQADYGMQSLAYELNVEGARLARQ
VADAKTAETPDKPRFVAGVLGPTSRTCSISPDVNNPGYRNVTFDELVENYVEATRGLIEG
GADLILIETIFDTLNAKAAIFAVQGVFEELGVELPIMISGTITDASGRTLSGQTTEAFWN
SVRHARPISVGLNCALGAKELRPYIEELSTKADTHVSAHPNAGLPNAFGEYDESPAEMAV
VVEEFAAAGFLNIVGGCCGTTPAHIEAIAKAVAKYPPRAIPEIPRACRLSGLEPFTIDRS
SLFVNVGERTNITGSAKFARLIREENYAEALEVAQQQVEAGAQVIDINMDEGMLDSKAAM
VTFLNLIASEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEAFKHHARLC
KRYGAAVVVMAFDEDGQADTQARKEEICKRSYDILVDEVGFPPEDIIFDANIFAIATGIE
EHNNYAVDFINACAYIRDNLPYALSSGGVSNVSFSFRGNNPVREAIHSVFLYYAIRNGLT
MGIVNAGQLEIYDEIPKALRDRVEDVVLNRTPEATEALLAIADDYKGGGAVKEAEDEEWR
SYSVEKRLEHALVKGITTWIVEDTEECRQQCARPIEVIEGPLMSGMNVVGDLFGAGKMFL
PQVVKSARVMKQAVAHLIPFIEAEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNG
YDVVDLGVMVPAEKILQTAIAEKCDIIGLSGLITPSLDEMVHVAKEMQRQNFQLPLMIGG
ATTSKAHTAVKIDPQYSNDAVVYVTDASRAVGVATSLLSKELKADYVARTRADYAVVRER
TANRSARTERLSYEQAIANKPAFDWAGYQAPTPSFTGVRVLDEIDLAVLAEYIDWTPFFI
SWDLAGKYPRILTDEVVGEAATSLFNDAQAMLKKLIDEKLIKARAVFGFWPANQVEHDDL
EVYGADGETLATLHHLRQQTIKPDGKPNLSLADFVAPKESGVRDYIGGFITTAGIGAEEV
AKAYEAKGDDYNSIMVKALADRLAEACAEWLHERVRKEYWGYARDEHLDNEALIKEQYVG
IRPAPGYPACPDHTEKGTLFELLDPQGLSGVSLTEHYAMFPAAAVSGWYFAHPQAQYFAV
GKIDKDQVERYSQRKGQEASVSERWLAPNLGYDD
NT seq 3705 nt   +upstreamnt  +downstreamnt
atgtccagcccgctcaccgatcgcagcgcccgcctgcaagccctccagcacgccctcagg
gaacgtatcctgatcctcgatggcggcatgggcaccatgatccagagctacaagctggaa
gaggccgactaccgcggcgagcgcttcgccgactggccgagcgacgtgaaaggcaacaac
gacctcttgctgctgagccgcccggacgtgatccaggccatcgagaaggcctacctcgac
gccggcgccgacatcctcgagaccaacaccttcaacgccacccaggtgtcccaggccgac
tacggcatgcagtcgctggcctacgaactcaacgtcgaaggggcgcgcctggcccgccag
gtggcggacgcgaagaccgccgagaccccggacaagccgcgtttcgtcgccggcgtgctc
ggcccgaccagccgcacctgctcgatttccccggacgtgaacaaccccggctaccgcaac
gtcaccttcgacgaactggtggagaactacgtcgaggcgacccgaggcctgatcgaaggc
ggcgccgacctgatcctgatcgagaccatcttcgacaccctcaacgccaaggcggcgatc
ttcgccgtccagggcgtgttcgaggaactcggcgtggagctgccgatcatgatctccgga
accatcaccgacgcctccggccgcaccctgtcgggccagaccaccgaggccttctggaac
tcggtgcggcatgcccggccgatctcggtaggcctgaactgcgccctcggcgccaaggaa
ttgcggccgtacatcgaggaactgtcgaccaaggccgacactcatgtctcggcccacccc
aacgccggcctgccgaacgccttcggcgaatacgacgaatcgccggcggaaatggccgtg
gtggtcgaggaattcgccgccgccggcttcctcaatatcgtcggcggctgctgcggcacc
accccggcgcacatcgaggcgatcgccaaggcagtggccaagtacccgccgcgggccatc
ccggagattccccgggcctgtcgcctgtccggcctggagccgttcaccatcgaccgcagc
tcgctgttcgtcaacgtcggcgagcgcaccaacatcaccggttcggccaagttcgcccgg
ctgatccgcgaggaaaactacgcggaagctctcgaggtcgcccagcagcaggtggaagcc
ggcgcccaggtgatcgacatcaacatggacgaaggcatgctggactcgaaggcggccatg
gtcaccttcctcaacctgatcgcctccgagcccgacatctcgcgcgtgccgatcatgatc
gactcctccaagtgggaagtgatcgaggccggcctgaagtgcatccagggcaagggcatc
gtcaactcgatctcgatgaaggaaggcgtcgaggccttcaagcaccatgcccgcctgtgc
aagcgctacggcgccgcggtggtggtgatggccttcgacgaggacggccaggccgacacc
caggcgcgcaaggaagaaatctgcaagcgctcctacgacatcctggtcgacgaagtcggc
ttcccaccggaagacatcatcttcgatgcgaacatcttcgccatcgccaccggcatcgag
gaacacaacaactacgcggtcgatttcatcaacgcctgcgcctacatccgcgacaacctc
ccctacgccctgagctcgggcggggtgtccaacgtgtccttctcgttccgcggcaacaac
ccggtacgcgaggcgatccactcggtgttcctctactacgcgatccgcaacggcctgacc
atgggcatcgtcaacgccggccagctggaaatctacgacgagattccgaaagcgctgcgc
gaccgggtcgaggacgtggtgctcaaccgcacgcccgaggccaccgaggccctgctggcg
atcgccgacgactacaagggcggcggcgcggtcaaggaggccgaggacgaggaatggcgc
agctacagcgtcgagaagcgcctcgagcatgcgctggtcaagggcatcaccacctggatc
gtcgaggacaccgaggaatgccgccagcagtgtgcgcgtcccatcgaggtcatcgaaggt
ccgctgatgtccgggatgaacgtggtcggcgacctgttcggcgccggcaagatgttcctc
ccgcaggtggtcaagtccgcgcgagtgatgaagcaggcggtggcccacctgattcccttc
atcgaggcggagaaaggcgacaagccggaagccaagggcaagatcctgatggccacggtg
aagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtgctcggctgcaacggc
tatgacgtggtcgacctcggcgtgatggtgccggcggagaagatcctgcagaccgccatc
gccgagaaatgcgacatcatcggcctgtctggcctgatcacgccgtcgctggacgagatg
gtccacgtcgccaaggaaatgcagcggcagaatttccagttgccgctgatgatcggcggc
gccactacctcgaaggcgcataccgcggtgaagatcgatccgcagtacagcaacgacgcg
gtggtctacgtcaccgacgcctcgcgcgcggtaggcgtggccaccagcctgctgtccaag
gagctgaaggccgactacgtggcccgcacccgcgccgactacgcggtggtccgcgaacgc
acggccaaccgcagcgcccgcaccgagcggctgagctacgaacaggcgatcgccaacaag
ccggcgttcgactgggccggctaccaggcgccgacgccttccttcaccggcgtcagggtg
ctcgacgagatcgacctcgcggtgctcgccgagtacatcgactggacgccgttcttcatt
tcctgggacctggccggcaagtacccgcgcatcctcaccgacgaggtggtcggcgaggcc
gccacctcgttgttcaacgacgcccaggcgatgctgaagaagctgatcgacgagaagctg
atcaaggcccgcgcggtgttcggcttctggccggccaaccaggtcgagcacgacgacctg
gaggtctacggcgccgatggcgagaccctcgccaccctgcaccacctgcggcagcagacg
atcaagccggacggcaagccgaacctgtcgctggccgatttcgtcgcgccgaaggaaagc
ggcgtgcgcgactacatcggcggcttcatcaccaccgccgggatcggcgccgaggaagtg
gccaaggcgtacgaagccaagggcgacgactacaacagcatcatggtcaaggcgctcgcc
gaccgcctcgccgaagcctgcgccgagtggctgcacgagcgggtgcgcaaggagtactgg
ggctacgcccgcgacgaacacctcgacaacgaggccttgatcaaggagcaatacgtcggc
atccgcccggcaccgggctacccggcctgccccgaccataccgagaaaggcactctgttc
gaactgctcgatccgcagggcctgtccggcgtcagcctgaccgagcactacgcgatgttc
ccggccgcggcggtcagcggttggtatttcgcccacccgcaggcgcagtacttcgcggtc
ggcaagatcgacaaggaccaggtggaacgctacagccagcgcaagggccaggaagccagc
gtcagcgagcgctggctggcgccgaaccttggctacgatgactga

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