Pteropus alecto (black flying fox): 102897495 Help Entry 102897495         CDS       T02993                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pale  Pteropus alecto (black flying fox) Pathway pale00230   Purine metabolism pale01100   Metabolic pathways pale01522   Endocrine resistance pale04015   Rap1 signaling pathway pale04022   cGMP-PKG signaling pathway pale04024   cAMP signaling pathway pale04062   Chemokine signaling pathway pale04072   Phospholipase D signaling pathway pale04081   Hormone signaling pale04082   Neuroactive ligand signaling pale04114   Oocyte meiosis pale04211   Longevity regulating pathway pale04213   Longevity regulating pathway - multiple species pale04261   Adrenergic signaling in cardiomyocytes pale04270   Vascular smooth muscle contraction pale04371   Apelin signaling pathway pale04540   Gap junction pale04611   Platelet activation pale04713   Circadian entrainment pale04714   Thermogenesis pale04723   Retrograde endocannabinoid signaling pale04724   Glutamatergic synapse pale04725   Cholinergic synapse pale04726   Serotonergic synapse pale04727   GABAergic synapse pale04728   Dopaminergic synapse pale04750   Inflammatory mediator regulation of TRP channels pale04911   Insulin secretion pale04912   GnRH signaling pathway pale04913   Ovarian steroidogenesis pale04914   Progesterone-mediated oocyte maturation pale04915   Estrogen signaling pathway pale04916   Melanogenesis pale04918   Thyroid hormone synthesis pale04921   Oxytocin signaling pathway pale04923   Regulation of lipolysis in adipocytes pale04924   Renin secretion pale04925   Aldosterone synthesis and secretion pale04926   Relaxin signaling pathway pale04927   Cortisol synthesis and secretion pale04928   Parathyroid hormone synthesis, secretion and action pale04934   Cushing syndrome pale04935   Growth hormone synthesis, secretion and action pale04970   Salivary secretion pale04971   Gastric acid secretion pale04972   Pancreatic secretion pale04976   Bile secretion pale05012   Parkinson disease pale05030   Cocaine addiction pale05031   Amphetamine addiction pale05032   Morphine addiction pale05034   Alcoholism pale05163   Human cytomegalovirus infection pale05166   Human T-cell leukemia virus 1 infection pale05200   Pathways in cancer pale05207   Chemical carcinogenesis - receptor activation pale05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pale00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102897495 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102897495 (ADCY5)    04371 Apelin signaling pathway     102897495 (ADCY5)    04072 Phospholipase D signaling pathway     102897495 (ADCY5)    04024 cAMP signaling pathway     102897495 (ADCY5)    04022 cGMP-PKG signaling pathway     102897495 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102897495 (ADCY5)    04081 Hormone signaling     102897495 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102897495 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102897495 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102897495 (ADCY5)    04062 Chemokine signaling pathway     102897495 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102897495 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102897495 (ADCY5)    04912 GnRH signaling pathway     102897495 (ADCY5)    04913 Ovarian steroidogenesis     102897495 (ADCY5)    04915 Estrogen signaling pathway     102897495 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102897495 (ADCY5)    04921 Oxytocin signaling pathway     102897495 (ADCY5)    04926 Relaxin signaling pathway     102897495 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102897495 (ADCY5)    04918 Thyroid hormone synthesis     102897495 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102897495 (ADCY5)    04916 Melanogenesis     102897495 (ADCY5)    04924 Renin secretion     102897495 (ADCY5)    04925 Aldosterone synthesis and secretion     102897495 (ADCY5)    04927 Cortisol synthesis and secretion     102897495 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102897495 (ADCY5)    04270 Vascular smooth muscle contraction     102897495 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102897495 (ADCY5)    04971 Gastric acid secretion     102897495 (ADCY5)    04972 Pancreatic secretion     102897495 (ADCY5)    04976 Bile secretion     102897495 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102897495 (ADCY5)    04727 GABAergic synapse     102897495 (ADCY5)    04725 Cholinergic synapse     102897495 (ADCY5)    04728 Dopaminergic synapse     102897495 (ADCY5)    04726 Serotonergic synapse     102897495 (ADCY5)    04723 Retrograde endocannabinoid signaling     102897495 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102897495 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102897495 (ADCY5)    04213 Longevity regulating pathway - multiple species     102897495 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102897495 (ADCY5)    04714 Thermogenesis     102897495 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102897495 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102897495 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102897495 (ADCY5)    05163 Human cytomegalovirus infection     102897495 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102897495 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102897495 (ADCY5)    05031 Amphetamine addiction     102897495 (ADCY5)    05032 Morphine addiction     102897495 (ADCY5)    05034 Alcoholism     102897495 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102897495 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102897495 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102897495 (ADCY5) Enzymes [BR:pale01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102897495 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC DUF2339 Motif Other DBs NCBI-GeneID:  102897495 NCBI-ProteinID:  XP_006905658 LinkDB All DBs Position Unknown AA seq 1181 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADARANGYPHAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRGSLAGSGAGPGPVLSLGACCLA LLQIFRSKKFPSDKLERLYQRYFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYL GVLAAAVGVILVMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWW TVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNI VGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAK QEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCL RIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVH CGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAY LKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSK EMKRMGFEDPKDKXXXXXXNPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEK KYSKQVDDRFGAYVACASLVFLFICFVQITIVPQKGPGVMLVLERDDGGGRAGSVVVREV PAEFCSVSHLPTPQLFPAPLQTLSRKIVRSKVNSTLVGVFTITLVFLAAFVNMFMCNSKD LFGCLADEHNISTSQVNACHVVESAFNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLA CSVFLQISCIGKLVLMLAIELIYVLVVEVPGVTLFDNADLLVTANAIDFNNNGTSQCPEH ATKVALKVVTPIVISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLL HNILPKDVAAHFLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLL NEIIADFDEIISEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMD QMKYINEHSFNNFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQV TTDMYQVLAANTYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3546 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagccgcggcgcca gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgatgcccgcgccaat ggctacccccacgcccccggcggttcggcccgcggctccaccaagagacccgggggggcg gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgacgac cctccgctgagtggcgacgaccccttggccgggggctttggcttcagcttccgcggcagc ttggcgggctcgggcgcgggccccggcccggtgctgtcgctgggcgcctgctgcctggca ctgctgcagatattccgctccaagaagttcccgtcggacaagctggagcggctgtaccag cgctacttcttccgtctgaaccagagcagcctgaccatgctcatggccgtgctagtgctc gtgtgcctcgtcatgttggccttccacgcggcgcggcctccgctccagctgccctacctg ggcgtgctggcggccgccgtgggcgtgatcctcgtcatggccgtgctctgcaaccgcgcc gcctttcaccaggaccacatgggcctggcctgctacgcgctcatcgcggtggtgctggcc gtccaggtggtgggcctgctgctgccccagccacgaagcgcctccgagggcatctggtgg acggtgttcttcatctacaccatctacacactgctacccgtgcgcatgcgggccgcagta ctcagcggggtgctcctgtctgccctccacctggccatcgccctgcgaaccaacgcccag gaccagttcctgctcaaacagctggtctccaatgtcctcattttctcctgcaccaacatc gtgggtgtctgcacccactatccggcagaggtctcccagagacaggccttccaggagacc cgggagtgtatccaggcacggctccactcacagcgggagaaccagcagcaggagcggctc ctgctgtctgtccttccccgtcatgttgccatggagatgaaagcagacatcaacgccaag caggaggatatgatgttccataagatttacatccagaaacatgacaatgtgagcatcctg tttgctgacatcgagggcttcaccagcctggcgtcccagtgcacggcccaagagctggtt atgaccctcaacgagctcttcgcccgcttcgacaagctggctgcggagaatcactgttta cgtattaagatcctgggggattgttattactgtgtctcggggctgcctgaagcgagggct gaccacgcccactgctgtgtggagatgggcatggacatgattgaggccatctcgttggtc cgggaggtgacaggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagtacac tgcggtgtccttggtctcaggaagtggcaattcgacgtctggtctaacgacgtcacgctg gccaaccacatggaggctggaggcaaggctggacgcatccacatcaccaaggccacactc aactacctgaatggagactacgaggtggagccgggctgtgggggcgagcgcaatgcctac ctcaaggagcacagcatcgagaccttcctcatcctgcgctgcacccagaagcggaaagaa gagaaggccatgatcgccaagatgaatcgccagagaaccaactccattgggcacaacccg ccgcactggggggctgagcgccccttctacaaccacttgggcggcaaccaggtgtccaag gagatgaagcggatgggcttcgaagaccccaaggacaagnnnnnnnnnnnnnnnnnnaac cccgaggatgaagtggatgaattcctgggccgagccatcgacgccaggagtattgacagg ctgcggtctgagcatgttcgcaagttcctcttgaccttcagggagcctgacttagagaag aagtactccaagcaggtggatgaccgattcggtgcctatgtggcgtgtgcctcgcttgtc ttcctcttcatttgctttgtccagatcaccatcgtgccccagaagggtcctggggttatg ctggtgctggagagagacgacggtggagggagggctggttctgtggtggttcgtgaagtg cccgctgaattctgttctgtctctcatctccccaccccacagctcttccccgcccctctg cagaccctctccaggaagatcgtgcggtccaaggtgaacagcaccctggttggggtgttc accatcaccctggtgttcctggcagcatttgtcaacatgttcatgtgcaactccaaggac ctattcggctgcctggcggatgagcacaacatcagcaccagccaggtcaacgcttgccac gtggtggagtcggccttcaactacagcctgggtgacgagcagggattctgtggcagcccc tggcccaactgcaacttccctgagtacttcacctacagcgtgctgctcagcctgctggcc tgctccgtgttcctgcagatcagctgcatcgggaagctggtgctcatgctggccatcgag ctcatatatgtgctcgtcgtcgaagtgcccggtgtcacactctttgacaatgcagacctg ctagtcaccgccaacgccatagacttcaacaacaacgggacctcccagtgccctgagcac gcgaccaaagtggcgctgaaggtggtgacgcccattgtcatctcagtctttgtgctggcc ctgtacctgcacgcccagcaggtggagtccaccgcccgcctcgacttcctctggaaactg caggccacggaggagaaggaggagatggaggagctgcaggcctacaaccggcggctgctg cacaacatcctgcccaaggacgtggccgcccacttcctggcccgtgagcggcgcaacgac gagctctactatcagtcgtgtgagtgtgtggccgtcatgttcgcctccatcgctaacttc tccgagttctatgtggagctggaggccaacaacgagggtgtcgagtgcttgcggctgctt aatgaaatcatcgccgattttgacgagatcatcagcgaggatcggttcaggcagctggaa aagatcaagaccattggcagcacctacatggctgcctcaggcctcaatgattccacctat gacaaggtgggcaagacccacatcaaggctctggccgacttcgccatgaagctgatggac cagatgaagtacatcaacgagcactccttcaacaacttccagatgaagattgggctcaat attggccccgtggtggccggggtgatcggggcccgcaagcctcagtacgacatctggggc aatacggtgaatgtggccagccgcatggacagcacaggtgtgcctgaccgcatccaggtc accacggacatgtatcaggtgctggctgccaacacataccagctggagtgccggggtgtg gtcaaggtcaagggcaaaggcgagatgatgacctacttcctcaacggagggcccccgctc agttag

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