Pteropus alecto (black flying fox): 102898575
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Entry
102898575 CDS
T02993
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale04022
cGMP-PKG signaling pathway
pale04068
FoxO signaling pathway
pale04081
Hormone signaling
pale04140
Autophagy - animal
pale04152
AMPK signaling pathway
pale04211
Longevity regulating pathway
pale04213
Longevity regulating pathway - multiple species
pale04910
Insulin signaling pathway
pale04920
Adipocytokine signaling pathway
pale04923
Regulation of lipolysis in adipocytes
pale04930
Type II diabetes mellitus
pale04931
Insulin resistance
pale04932
Non-alcoholic fatty liver disease
pale04935
Growth hormone synthesis, secretion and action
pale05010
Alzheimer disease
pale05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
102898575 (IRS2)
04022 cGMP-PKG signaling pathway
102898575 (IRS2)
04152 AMPK signaling pathway
102898575 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
102898575 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102898575 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
102898575 (IRS2)
04923 Regulation of lipolysis in adipocytes
102898575 (IRS2)
04920 Adipocytokine signaling pathway
102898575 (IRS2)
04935 Growth hormone synthesis, secretion and action
102898575 (IRS2)
09149 Aging
04211 Longevity regulating pathway
102898575 (IRS2)
04213 Longevity regulating pathway - multiple species
102898575 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
102898575 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
102898575 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102898575 (IRS2)
04932 Non-alcoholic fatty liver disease
102898575 (IRS2)
04931 Insulin resistance
102898575 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
102898575
NCBI-ProteinID:
XP_024900741
LinkDB
All DBs
Position
Unknown
AA seq
1410 aa
AA seq
DB search
MASPPLQGPPGLAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAVGDEA
TATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTK
DEYFAVAAENEQEQEGWYRALTDLVSEGRAVAGDAPSSAATAGSCSASLPGALGGSAGAD
DSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV
RTASEGDGGAATGTGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGSRAXXXXXXXX
XXXXMSMPLAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLQHHAGQRPSSGSA
SASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGSELYGYMTMDR
PLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSG
SSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVALMGGGS
GSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGAAVPAPASVASRAFPVNGASYKAS
SPAESSPEDSGYMRMWCGSKLTMENTDSKLLPNGDYLNMSPSDAGTSETPPDDFSAGLHS
GGEMLXXXXXXXXXXXXXXXXXXXXXXXXAPYTCSGDNDQYVLMSSPVGRILEEERPEPQ
ASAGTTQSASVFVAGMGGGSHTQLPHSVVPSPGRLSGSGCGRPEGFLNQRCRAVRPTRLS
LEGLQTLPRMHEYPLPPEPKSPGEYINIDFSETGARLSPPAPPLLASAASSSSLLSASSP
ASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTQSGDPVGSLDALLSPEASSQY
PPLPPRPAAPSSSLQPQPPPPPPPGELYRLPPASTSQGPSAASSSSSETGDNGDYTEMAF
GVAATPPQPIVAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIR
ADPQGGRRRHSSETFSSTTTVTSVSPSFAHNPKRHNSASVENVSLRKNSEGGGSGILGGG
DEPSSSPHQLQPPLPQQARPWTPNQPGGLVGCPGSSGSPMRRETSAGFQNGLNYIAIDVR
DEPGLLSPQQQHPHSQQHPHSQSGDKSTWGRTRSLGGLISAVGANSTGGVCGGPGPGALP
SANTYASIDFLSHHLKEATIVKDTHDLPRKAPLSCAEEASWPSAAPSTHNASCSENLPLL
DPLPSATVAAVVGGGQSHLAGQLCVSNPSG
NT seq
4233 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcaggggccccccgggttggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcggccccggcgcggttggcgacgaggca
actgccacagcgggcgggggtccggcgccgcagccgccgcggctcgagtactacgagagc
gagaagaagtggcggagcaaggctggcgccccgaagcgggtcatctcgcttgactgctgc
ttgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaag
gacgagtacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcg
ctcaccgacctggtcagcgagggccgcgcggttgccggcgacgcgccctcctccgccgcc
actgctgggtcctgcagcgcctctttgcctggcgccctgggcggctcggccggcgctgat
gacagctacgggctggtggcgcccgccacagccgcctaccgcgaggtgtggcaggtgaac
ctgaagcccaagggcctgggtcagagcaaaaacctgacgggcgtgtaccgcctttgcctg
tcggcgcgcaccatcggcttcgtgaagctcaactgcgagcagccgtcggtgactctgcaa
ctcatgaacattcgccgctgcggccactcggacagtttcttcttcatcgaggttggccgc
tcagctgtcaccggccccggcgagctgtggatgcaggccgacgactcggtggtggcgcag
aacatccatgagaccatcctagaggccatgaaggcgctcaaggagctctttgagttccgg
ccgcgcagcaagagccagtcgtcgggatcatcagccacgcaccccattagcgtccccggc
gcgcgccgtcaccaccacctggtcaacctgccccccagccagacgggtttggtgcggcgc
tcgcgcaccgacagcctggctgccaccccgccggccgccaaatgtagctcctgccgggtg
cgcacggccagcgagggcgacggcggcgcagcgacggggactggggcggcgggcggcagg
cccgtgtcggtggcggggagccccctgagcccggggcccgtgcgcgcgccgcttagtcgt
tcgcataccctgagcggcggctgcggcagccgcgcnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnncgatgtccatgcccctggctcactcgccccctgccgctaccagccccgga
agcctgtcttccagcagtgggcacggctcgggctcctacccgccgcctccgggcccgcac
ccacacctacagcaccccttgcagcaccacgcgggccagcggccttccagcggcagcgcc
tcagcctccggctcccccagcgatcccggctttatgtctctggatgagtacggctccagc
cctggggacctgagagccttctgtagccacaggagcaacactcctgagtccatcgccgag
acacctccggccagggacggcagcgggagtgagctgtacggctacatgaccatggacagg
cccctgagccactgtggccgcccctaccgtcgtgtctcaggggacggagctcaggacttg
gacagagggctaaggaagaggacttactccctgaccacacctgcccggcagcgaccggtg
ccccagccctcctcagcgtccctggatgaatacaccctgatgcgggccaccttctctggc
agctcgggccgcctctgcccgtcctgccctgcgtcttctcccaaagtggcctaccacccc
tatcccgaggactacggcgacattgagattgggtcccataggagctccagcagtaacctg
ggcacggacgatggctacatgcccatgacccctggcgtggccctcatgggtggtggcagt
ggcagctgcaagagtgatgactacatgcccatgagtcccaccagcgtgtctgccccaaag
cagatcttgcagccacgggctgctgcagcagccttgccccccacaggagctgcagtgcca
gcgccggcctctgtggccagcagggcctttccagtgaacggggccagctacaaggccagc
tccccggccgagagctctcccgaagacagtggatacatgcgcatgtggtgtggttccaag
ctgaccatggagaatacagacagcaagctgcttcccaacggggactacctcaacatgtcc
cccagcgatgcaggcacctcggaaaccccgccagatgacttctcagcaggcttgcatagc
ggtggggagatgctcnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnggctccttacacctgtagtggggacaatgaccag
tacgtactcatgagctccccggtggggcgcatcctagaagaggagaggccagagccacag
gccagcgcagggaccacgcagtcggccagcgtcttcgtggctgggatgggtgggggcagc
cacacccagcttcctcactccgtagtgccttcgcctgggaggctgagtggcagcggctgt
ggccgcccagagggtttcctgaaccaacgctgtcgggcagtgcgacccacgcgcctgtcc
ctggaggggcttcagaccctacccaggatgcatgagtatcctctgccgccggaacccaag
agcccgggcgaatacatcaacattgactttagcgaaaccggagcgcgcttgtcaccgcct
gcccctccgctgctggcttccgctgcctcgtcctcctcgctgctgtctgccagcagccca
gcctcatccctgggctctggtactccgggcacaagcagcgacagccggcagcgctccccg
ctctccgactacatgaacctcgatttcagttcgcccaagtcacccaaaccgagtacccag
agcggggacccggtggggtccttggatgctctcctgtctcctgaggcctcctcccagtac
ccgccactgcctcctcgccctgctgccccctcctcctccttgcagccgcagccgcctccc
ccacctcccccaggggagctgtaccgcctgcctccagcatccacatcccagggccccagc
gctgcctcctcttcgtcctcggagactggggacaatggtgactacaccgagatggccttt
ggcgtagctgccaccccgccacaacccatcgtggcccccccgaagccggaaggtgcccgt
gtgaccagccccacgtccggcctgaagaggctgagtctcatggatcaggtgtctggagtg
gaggcctttttgcaggctggccagcccccagacccacaccggggggccaaggtcatccgg
gcagacccgcaggggggccgccgccgccacagttcggagaccttttcctcgaccaccact
gtgacttccgtgtccccatccttcgcccacaacccgaagcgccacaactcggcctccgtg
gaaaacgtctctctcaggaaaaacagcgaaggaggtggcagtggcatccttggtgggggc
gacgaaccttcctcttccccccaccagttgcaaccacccctcccccagcaggcacggcca
tggacaccgaatcagcctgggggtctggttggctgccctgggagcagtggttctcctatg
cgcagggagacctctgccggcttccagaatggcctcaactacatcgccatcgatgtgaga
gatgagccagggctgttgtctccccaacaacaacacccgcattcgcagcaacatccacat
tcgcagtcaggcgacaagagtacttggggccggacccgtagcctcgggggtctcatcagc
gctgtgggggccaacagcacaggtggagtgtgtggggggcccggccctggcgccctaccc
tcagccaacacctatgccagcattgacttcttgtcccatcacctgaaggaggccaccatt
gtgaaagacacccatgatctacccagaaaagcccccctctcctgtgcagaggaggcctct
tggccatcagcagccccctccacccataatgcctcctgctctgagaacctgcctctgctg
gaccccctgccctccgccacagtggctgctgttgtcgggggagggcagtcccacttggct
gggcagctctgtgtttccaacccatcaggctga
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