Papio anubis (olive baboon): 101026547 Help Entry 101026547         CDS       T07474                                  Name (RefSeq) ryanodine receptor 1   KO K04961   ryanodine receptor 1 Organism panu  Papio anubis (olive baboon) Pathway panu04020   Calcium signaling pathway panu04371   Apelin signaling pathway panu04713   Circadian entrainment panu04730   Long-term depression panu04921   Oxytocin signaling pathway panu05017   Spinocerebellar ataxia panu05020   Prion disease panu05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:panu00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101026547    04020 Calcium signaling pathway     101026547  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     101026547   09156 Nervous system    04730 Long-term depression     101026547   09159 Environmental adaptation    04713 Circadian entrainment     101026547  09160 Human Diseases   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     101026547    05020 Prion disease     101026547    05022 Pathways of neurodegeneration - multiple diseases     101026547  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:panu01009]     101026547   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:panu04147]     101026547    04040 Ion channels [BR:panu04040]     101026547 Protein phosphatases and associated proteins [BR:panu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      101026547 Exosome [BR:panu04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    101026547 Ion channels [BR:panu04040]  Voltage-gated cation channels   Ryanodine receptor    101026547 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 Ins145_P3_rec MIR SPRY RIH_assoc Ion_trans EF-hand_7 Motif Other DBs NCBI-GeneID:  101026547 NCBI-ProteinID:  XP_031514899 Ensembl:  ENSPANG00000020887 LinkDB All DBs Position 20:complement(17990772..18159356) Genome browser AA seq 4781 aa AA seqDB search MADAEGEDDVQFLRTDDEVVLQCSATVLKEQLKLCLAAEGFGNRLCFLEPTSNAQNVPPD LAICCFVLEQSLSVRALQEMLANTVEAGVESSQGGGHRTLLYGHAILLRHAHSRMYLSCL TTSRSMTDKLAFDVGLQEDAIGEACWWTTHPASKQRSEGEKVRVGDDIILVSVSSERYLH LSTASGELQVDASFMQTLWNMNPICSRCEEGFVTGGHVLRLFHGHMDECLTISPADSDDQ RRLVYYEGGAVCTHARSLWRLEPLRISWSGSHLRWGQPLRVRHVTTGRYLALTEDQGLVV VDASKAHTKATSFCFRISKEKLDVAPKRDVEGMGPPEIKYGESLCFVQHVASGLWLTYAA PDPKALRLGVLKKKAMLHQEGHMDDALSLTRCQQEESQAARMIHSTNGLYNQFIKSLDSF SGKPRGSGPPAGTALPIEGVILSLQDLIIYFEPPSEDLQHEEKQSKLRSLRNRQSLFQEE GMLSLVLNCIDRLNVYTTAAHFAEFAGEEAAESWKEIVNLLYELLASLIRGNRSNCALFS TNLDWLVSKLDRLEASSGILEVLYCVLIESPEVLNIIQENHIKSIISLLDKHGRNHKVLD VLCSLCVCNGVAVRSNQDLITENLLPGRELLLQTNLINYVTSIRPNIFVGRAEGTTQYSK WYFEVMVDEVTPFLTAQATHLRVGWALTEGYSPYPGGGEGWGGNGVGDDLYSYGFDGLHL WTGHVARPVTSPGQHLLAPEDVVSCCLDLSVPSISFRINGCPVQGVFESFNLDGLFFPVV SFSAGVKVRFLLGGRHGEFKFLPPPGYAPCHEAVLPRERLHLEPIKEYRREGPRGPHLVG PSRCLSHTDFVPCPVDTVQIVLPPHLERIREKLAENIHELWALTRIEQGWTYGPVRRCLQ ISHSLPEPERNYNLQMSGETLKTLLALGCHVGMADEKAEDNLKKTKLPKTHSSILCTDIS IYGSVWGTLIGKMETLWGDPSSIPHALNLTLRMSVFIYLSLPASLSLHFSVCLPTPCLLW PSSQGQRWHLGSEPFGRPWQPGDVVGCMIDLTENTIIFTLNGEVLMSDSGSETAFREIEI GDGFLPVCSLGPGQVGHLNLGQDVSSLRFFAICGLQEGFEPFAINMQRPVTTWFSKSLPQ FEPVPLEHPHYEVARVDGTVDTPPCLRLTHRTWGSQNSLVEMLFLRLSLPVQFHQHFRCT AGATPLAPPGLQPPAEDEARAAEPDPDYENLRRSAGGWGEAENGKEGTAKEGAPGGTPQA GGEAQPARAENEKDATTEKNKKRGFLFKAKKVAMMTQPPATPTLPRLPHDVVPADNRDDP EIILNTTTYYYSVRVFAGQEPSCVWVGWVTPDYHQHDMSFDLSKVRVVTVTMGDEQGNIH SSLKCSNCYMVWGGDFVSPGQQGRISHTDLVIGCLVDLATGLMTFTANGKESNTFFQVEP NTKLFPAVFVLPTHQNVIQFELGKQKNIMPLSAAMFQSERKNPAPQCPPRLEMQMLMPVS WSRMPNHFLQVETRRAGERLGWAVQCREPLTMMALHIPEENRCMDILELSERLDLQRFHS HTLRLYRAVCALGNNRVAHALCSHVDQAQLLHALEDAHLPGPLRAGYYDLLISIHLESAC RSRRSMLSEYIVPLTPETRAITLFPPGRSTENGHPRHGLPGVGVSTSLRPPHHFSAPCFV AALPAAGAAEAPARLSPAIPLEALRDKALRMLGEAVRDGGQHARDPVGGSVEFQFVPVLK LVSTLLVMGIFGDEDVKQILKMIEPEVFTEEEEEEEEEEEEEEEDEEEKEEDEEETAQEK EDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQHRVESLAAFAE RYVDKLQANQRSRYGLLMKAFSMTAAETARRTREFRSPPQEQINMLLQFKDGTDEEDCPL PEEIRQDLLDFHQDLLAHCGIQLDGEEEEPEEETTLGSRLMSLLEKVRLVKKKEEKPEEE RPAEESKPRSLQELVSHMVVRWAQEDFVQSPELVRAMFSLLHRQYDGLGELLRALPRAYT ISPSSVEDTMSLLECLGQIRSLLIVQMGPQEENLMIQRIGNIMNNKVFYQHPNLMRALGM HETVMEVMVNVLGGGESKEIRFPKMVTSCCRFLCYFCRISRQNQRSMFDHLSYLLENSGI GLGMQGSTPLDVAAASVIDNNELALALQEQDLEKVVSYLAGCGLQSCPMLVAKGYPDIGW NPCGGERYLDFLRFAVFVNGESVEENANVVVRLLIRKPECFGPALRGEGGSGLLAAIEEA IRISEDPARDGPGIRRDRRREHFGEEPPEENRVHLGHAIMSFYAALIDLLGRCAPEMHLI QACKGEALRIRAILRSLVPLEDLVGIISLPLQMPTLGKDGALVQPKMSASFVPDHKASMV LFLDRVYGIENQDFLLHVLDVGFLPDMRAAASLDTATFSTTEMALALNRYLCLAVLPLIT KCAPLFAGTEHRAIMVDSMLHTVYRLSRGRSLTKAQRDVIEDCLMALCRYIRPSMLQHLL RRLVFDVPILNEFAKMPLKLLTNHYERCWKYYCLPTGWANFGVTSEEELHLTRKLFWGIF DSLAHKKYDPELYRMAMPCLCAIAGALPPDYVDASYSSKAEKKATVDAEGNFDPRPVETL NVIIPEKLDSFINKFAEYTHEKWAFDKIQNNWSYGENIDEELKTHPMLRPYKTFSEKDKE IYRWPIKESLKAMIAWEWTIEKAREGEEEKTEKKKTRKISQSAQTYDPREGYNPQPPDLS AVTLSRELQAMAEQLAENYHNTWGRKKKQELEAKGGGTHPLLVPYDTLTAKEKARDREKA QELLKFLQMNGYAVTRGLKDMELDSSSIEKRFAFGFLQQLLRWMDISQEFIAHLEAVVSS GRVEKSPHEQEIKFFAKILLPLINQYFTNHCLYFLSTPAKVLGSGGHASNKEKEMITSLF CKLAALVRHRVSLFGTDAPAVVNCLHILARSLDARTVMKSGPEIVKAGLRSFFESASEDI EKMVENLRLGKVSQARTQVKGVGQNLTYTTVALLPVLTTLFQHIAQHQFGDDVILDDVQV SCYRTLCSIYSLGTTKNIYVEKLRPALGECLARLAAAMPVAFLEPQLNEYNACSVYTTKS PRERAILGLPNSVEEMCPDIPVLERLMADIGGLAESGARYTEMPHVIEITLPMLCSYLPR WWERGPEAPPPALPAGAPPPCTAVTSDHLNSLLGNILRIIVNNLGIDEASWMKRLAVFAQ PIVSRARPELLQSHFIPTIGRLRKRAGKVVSEEEQLRLEAKAEAQEGELLVRDEFSVLCR DLYALYPLLIRYVDNNRAQWLTEPNPSAEELFRMVGEIFIYWSKSHNFKREEQNFVVQNE INNMSFLTADNKSKMAKAGDTQSGGSDQERTKKKRRGDRYSVQTSLIVATLKKMLPIGLN MCAPTDQDLITLAKTRYALKDTDEEVREFLNNNLHLQGKVEGSPSLRWQMALYRGVPGRE EDADDPEKIVRRVQEVSAVLYYLDQTEHPYKSKKAVWHKLLSKQRRRAVVACFRMTPLYN LPTHRACNMFLESYKAAWILTEDHSFEDRMIDDLSKAGEQEEEEEEVEEKKPDPLHQLVL HFSRTALTEKSKLDEDYLYMAYADIMAKSCHLEEGGENGEGEEEVEVSFEEKEMEKQRLL YQQARLHTRGAAEMVLQMISACKGETGAMVSSTLKLGISILNGGNAEVQQKMLDYLKDKK EVGFFQSIQALMQTCSVLDLNAFERQNKAEGLGMVNEDGTVINRQNGEKVMADDEFTQDL FRFLQLLCEGHNNDFQNYLRTQTGNTTTINIIICTVDYLLRLQESISDFYWYYSGKDVIE EQGKRNFSKAMSVAKQVFNSLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMMMKLA QDSSQIELLKELLDLQKDMVVMLLSLLEGNVVNGTIARQMVDMLVESSSNVEMILKFFDM FLKLKDIVGSEAFQDYVTDPRGLISKKDFQKAMDSQKQFSGPEIQFLLSCSEADENEMIN CEEFANRFQEPARDIGFNVAVLLTNLSEHVPHDPRLHNFLELAESILEYFRPYLGRIEIM GASRRIERIYFEISETNRAQWEMPQVKESKRQFIFDVVNEGGEAEKMELFVSFCEDTIFE MQIAAQISEPEGEPETDEDEGAAEAGVEGAEESAAGPEGTAATAAAGATARVAAAMGRAL RGLSYRSLRRRVRRLRRLTAREAATAVAALLWAAVTRAGAAGAGAAAGALGLLWGSLFGG GLVEGAKKVTVTELLAGMPDPTSDEVHGEQPAGPGGDADGEGASEGAGDAAEGAGDEEEA VDEAGPGGADGAVAVTDGGPFRPEGAGGLGDMGDTTPAEPPTPEGSPILKRKLGVDGVEE ELPPEPEPEPELEPEKADAENGEKEEVPEPPPEPPKKQAPPSPPPKKEEAGGEFWGELEV QRVKFLNYLSRNFYTLRFLALFLAFAINFILLFYKVSDSPPGEDDMEGSAAGDVSGAGSG GGSGWGLGAGEEAEGDEDENMVYYFLEESTGYMEPALRCLSLLHTLVAFLCIIGYNCLKV PLVIFKREKELARKLEFDGLYITEQPEDDDVKGQWDRLVLNTPSFPSNYWDKFVKRKVLD KHGDIYGRERIAELLGMDLATLEITAHNERKPDPPPGLLTWLMSIDVKYQIWKFGVIFTD NSFLYLGWYMVMSLLGHYNNFFFAAHLLDIAMGVKTLRTILSSVTHNGKQLVMTVGLLAV VVYLYTVVAFNFFRKFYNKSEDEDEPDMKCDDMMTCYLFHM NT seq 14346 nt NT seq  +upstreamnt  +downstreamnt atggctgacgcagaaggcgaggacgacgtccagttcctgcgcacggatgatgaggtggtc ctgcagtgcagcgccaccgtgctcaaggagcagctcaagctctgcctggccgctgagggt ttcggtaaccgcctgtgcttcctggagcccaccagcaacgcccagaatgtgccccctgat ctggccatctgttgcttcgtcctggagcagtccctgtccgtgcgagccctgcaggagatg ctggccaacacagtggaggccggcgtggagtcatcccagggcgggggacacaggacgctc ctgtatggccatgccatcttactccggcacgcacacagccgcatgtatctgagctgcctc accacctcccgctccatgactgacaagctggccttcgatgtgggactgcaggaggatgca ataggagaggcttgctggtggaccacgcacccagcctccaagcagaggtctgaaggagag aaggtccgtgttggggatgacatcatccttgtcagtgtctcctccgaacgctacctgcac ctgtcgactgccagcggggagctccaggttgatgcttccttcatgcagacgctgtggaac atgaaccccatctgctcccgctgcgaagagggcttcgtgacaggaggtcacgtcctccgc ctctttcatggacatatggatgagtgtctgaccatttcccctgctgacagtgacgaccag cgcagacttgtctactatgaagggggagctgtgtgcacccacgcccgctccctctggagg ctggagcccctgagaatcagctggagtgggagccacctacgctggggccagccactccga gtccggcatgtcaccaccgggcggtacctggcactcactgaggaccagggcctggtggtg gttgacgccagcaaggcccataccaaggctacgtccttctgcttccgcatctccaaggag aagctggatgtggcccctaagcgggatgtggaaggcatgggcccccctgagatcaagtac ggggagtcactgtgctttgtgcagcatgtggcctcaggactgtggctcacctatgccgct ccagaccccaaggccctgaggctcggtgtgctcaagaagaaggccatgctgcaccaggaa ggccacatggacgatgcactgtcactgacccgctgccagcaggaggagtcccaggccgcc cgcatgatccacagcaccaatggcctgtacaaccagttcatcaagagcctggacagcttc agcgggaagccacggggctcggggccgccggctggcacggcgctgcccatcgagggcgtt atcctgagcctgcaggacctcatcatctacttcgagccgccctccgaggacttgcagcat gaggagaagcagagcaagctgcgaagcctgcgcaaccgccagagtctcttccaggaggag gggatgctctccctggtcctgaattgcattgaccgcctaaatgtctacaccaccgctgcc cactttgccgagtttgcaggggaggaggcagccgagtcctggaaagagattgtgaatctt ctttatgaactcctggcttctctgatccgtggcaatcgtagcaactgtgccctcttctcc acaaacttggactggctggtcagcaagctggatcggctggaggcctcatctggcatcctg gaggtcctgtactgtgtcctcattgagagtccagaggttctgaacatcatccaggagaat cacatcaagtccatcatctccctcctggacaagcatgggaggaaccacaaggtcctggac gtgctgtgctccctgtgtgtgtgtaatggtgtggctgtacgctccaaccaagatcttatt actgagaacttgctgcctggccgtgagcttctgctgcagacaaacctcatcaactatgtc accagcatccggcccaacatcttcgtgggccgagcggagggcaccacgcagtacagcaaa tggtactttgaggtgatggtggacgaggtgactccatttctgacagctcaggccacccac ttgcgcgtgggctgggccctcaccgagggctacagcccctaccctgggggcggcgagggc tggggcggcaacggggtcggcgatgacctctattcctacggctttgatggactgcatctc tggacaggacacgtggcacgcccagtgacttccccagggcagcacctcctggcccctgaa gacgtagtcagctgctgtctggacctcagcgtgccgtccatctccttccgcatcaatggc tgccctgtgcagggcgtctttgagtccttcaacctggacgggcttttcttccctgttgtc agcttctcggctggtgtcaaggtgcggttcctccttggtggccgccatggcgaattcaag ttcctgcccccacctggctatgccccatgccatgaggctgtgctccctcgagagcgactc catcttgaacctatcaaggagtatcgacgggaggggccccgggggcctcacctggtgggc cccagtcgctgcctctcacacaccgactttgtgccctgccctgtggacaccgttcagatc gtcctgccaccccatctggagcgcattcgggagaagctggcggagaacatccacgagctc tgggcactgacccgcattgagcaaggctggacctacggcccggtgaggcgctgcctgcag atctcccacagccttccagagcccgagaggaactacaacctgcagatgtccggggagacg ctcaagactctgctggctctgggctgccacgtgggtatggcggatgagaaggcggaggac aacctgaagaagacaaaactccccaagacccactcatctattttgtgcacagatataagc atatatggatctgtatgggggacactgataggaaagatggagacactgtggggtgacccc tcttccataccacatgccctgaacctgacacttcgaatgtctgtcttcatatatctctcc ctccctgcttccttatctctccatttctctgtgtgtctccccacaccatgtcttctctgg ccctcctcacagggccagcgctggcacttgggtagtgaaccatttgggcgcccctggcag ccgggcgatgtcgttggctgtatgatcgacctcacagagaacaccattatcttcaccctc aatggcgaggtcctcatgtctgactcgggctccgaaacagccttccgggagattgagatt ggggacggcttcctgcccgtctgcagcttgggacctggccaggtgggtcacctgaacctg ggccaggacgtgagctccctgcggttctttgccatctgtggcctccaggaaggcttcgag ccatttgccatcaacatgcagcgcccagtcaccacctggttcagcaaaagcctgccccag tttgagccagtgccccttgaacaccctcactatgaggtagcccgagtggacggcactgtg gacacgcccccgtgtctgcgtctgactcaccgcacctggggctcccagaacagcctggtg gagatgctcttcctgcgactgagcctcccagtccagttccaccagcacttccgctgcacc gcaggggccaccccgctggcaccccccggcctgcagccccccgccgaggacgaggcccgg gcggcggaacccgaccctgactacgaaaacctgcgccgctcagctgggggctggggcgag gccgagaacggcaaagaagggactgcgaaggagggcgcccccgggggcaccccgcaggcg gggggagaggcacagcccgccagggctgagaatgagaaggacgccaccaccgagaagaac aagaagagaggcttcttattcaaggccaagaaggtcgccatgatgacccaaccaccggcc acccccacgctgcctcggctccctcacgatgtcgtgcctgcagacaaccgcgatgaccct gagatcatcctcaacaccaccacgtactattattccgtgagggtctttgccggacaggag cccagctgcgtgtgggtgggctgggtcactcctgactaccatcagcatgacatgagcttc gatctcagcaaggtccgggtcgtgacagtgaccatgggggatgaacaaggcaacatccac agcagcctcaagtgcagcaattgctacatggtgtggggtggggactttgtgagtcccggg cagcagggccggatcagccacacggatcttgtcattgggtgcctggtggacttggccact ggcttaatgacctttacagccaatggcaaagagagcaacacctttttccaggtggaaccc aacacaaagctatttcctgctgtcttcgtcctgcccacccaccagaacgtcatccagttt gagctggggaagcagaagaacatcatgccgttgtcagccgccatgttccagagcgagcgc aagaacccggccccgcagtgcccgccacggctggagatgcagatgctgatgccagtgtcc tggagccgcatgcccaaccacttcctgcaggtggagacgaggcgcgccggcgagcggctg ggctgggccgtgcagtgccgggagccgctgaccatgatggcgctgcacatccccgaggag aaccgatgcatggacatcctggagctgtcggagcgcctggacctgcagcgcttccactcg cacaccctgcgcctctaccgcgctgtgtgcgccctgggcaacaatcgcgtggcgcacgct ctgtgcagccacgtggaccaggctcagctgctgcacgccctggaggacgcgcacctgcca ggtccactgcgtgcaggctactacgacctcctcatcagcatccatctcgaaagtgcctgc cgcagccgccgctccatgctctctgaatacatcgtgcccctcacgcctgagacccgcgcc atcacgctcttccctcctggaaggagcacagaaaatggtcacccccggcacggcctgccg ggagttggagtcagcacttcgctgcggcccccgcatcatttctcggccccctgtttcgtg gccgctctgccagctgctggggcagcagaggctccggcccgcctcagccccgccatcccg ttggaggccctacgggacaaggcactgaggatgctgggggaggcggtgcgcgacggtggg cagcacgctcgcgaccccgtcgggggctccgtggagttccagtttgtgcctgtgctcaag ctcgtgtccacgctgctggtgatgggcatctttggcgatgaggatgtgaaacagatcttg aagatgattgagcctgaagtcttcactgaggaagaagaggaggaggaggaggaagaagag gaggaagaggaagatgaggaggagaaggaggaggatgaggaggaaacagcacaggaaaag gaagatgaagaaaaagaggaagaggaggcagcagaaggggagaaggaagaaggcttggag gaggggctgctgcagatgaagttgccagagtctgtgaagttacagatgtgccacctgctg gaatatttctgtgaccaagagttgcagcaccgtgtggagtccctggcagcctttgcggag cgctatgtggacaagctccaggccaaccagcggagccgctatggcctcctcatgaaagcc ttcagcatgaccgcagcggagactgcaagacgtacccgcgagttccgctccccgccccag gagcagatcaatatgctattgcaattcaaagatggtacagatgaggaagactgtcctctc cctgaagagatacgacaggatttgcttgactttcatcaagacctgctggcacactgtgga attcagctggatggagaggaggaggaaccagaggaagagaccaccctgggcagccgcctc atgagccttttggagaaagtgcggctggtgaagaagaaggaggagaaacctgaggaggag cggccagcagaggagagcaaaccccggtccctgcaggaactggtgtcccacatggtggtg cgctgggcccaagaggacttcgtgcagagccccgagctggtgcgggccatgttcagcctc ctgcaccggcagtacgacgggctgggtgagctgctgcgtgccctgccacgggcgtacacc atctcaccgtcctccgtggaagacaccatgagcctgcttgagtgcctcggccagatccgc tccctgctcatcgtgcagatgggccctcaggaggagaacctcatgatccagagaatcggg aacatcatgaacaacaaagtcttctaccaacacccaaacctgatgagggcgctgggcatg cacgagacggtcatggaggtcatggtcaacgtcctcgggggcggcgagtccaaggagatc cgcttccccaagatggtgacaagctgctgccgcttcctctgctatttctgccgcatcagc cggcagaaccagcgctccatgtttgaccacctgagctacctgctggagaacagtggcatc ggcctgggcatgcagggctccacgcccctggacgtggctgctgcctccgtcattgacaac aatgagctggccttggcgttgcaggagcaggacctggaaaaggtcgtgtcctacctggca ggctgtggcctccaaagctgccccatgcttgtggccaagggatacccagatattggctgg aacccctgcggtggagagcgctacctggacttcctgcgcttcgctgtcttcgtaaacggc gagagcgtggaggagaacgccaacgtggtggtgcggctgctcatccggaagcctgagtgc ttcggacccgccctgcggggtgagggtggctcagggctgctggctgccatcgaagaggcc atccgcatctccgaggaccctgcaagggatggcccaggcatccgcagggaccggcggcgc gagcacttcggtgaggaaccacctgaagaaaaccgggtgcacctgggacacgccatcatg tccttctatgctgccttgatcgacctgctcggacgctgtgcgccagagatgcatctaatc caagcctgcaagggtgaggccctgcggatccgtgccatcctccgctcccttgtgcccttg gaggacctcgtgggcatcatcagcctcccactgcagatgcccaccctgggcaaagacggg gctctggtgcagccaaagatgtcagcatccttcgtgccggaccacaaggcgtccatggtg ctcttcctggaccgtgtgtacggcattgagaaccaggacttcttgctgcacgtgctggac gtgggattcctgcccgacatgagggcagccgcctcgctggacacggccactttcagcacc accgagatggcactggcgctgaaccgctacctgtgcctggccgtgctgcctctcatcacc aagtgtgcgccgctctttgcgggcacggaacaccgcgccatcatggtggactccatgctg cacacggtgtaccgcctgtcccggggtcgctcgctcaccaaggcacagcgcgacgtcatc gaggactgcctcatggctctctgcaggtacatccgcccgtcgatgctgcagcacctgctg cggcgtctggtgttcgacgtgcccatcttaaacgagtttgccaagatgccactcaagctc ctcaccaaccactatgagcgttgttggaagtactactgcctacccacaggctgggccaac ttcggggtcacctcggaggaggagctgcacctcacccggaaactcttctggggcatcttt gactctctggcccataagaaatacgacccggagctttaccgaatggccatgccttgtctg tgtgccatcgctggggctctgccccccgactacgtggacgcctcatactcatctaaggcg gagaaaaaggccacagtggatgctgaaggcaactttgatccccggcctgtggaaaccctc aatgtgatcatcccggagaagctggactccttcattaacaagtttgcggagtatacacat gagaagtgggccttcgacaagatccagaacaactggtcctatggagagaacatagatgag gagttgaagacccaccccatgctgaggccctacaagaccttttcagagaaggacaaagag atataccgctggcccatcaaggagtccctgaaggccatgattgcctgggaatggaccata gagaaggccagggagggtgaggaggagaagacggaaaagaaaaaaacgcggaagatatca caaagtgcccagacctacgatcctcgagaaggctacaacccccagccccccgaccttagc gcagttaccctgtcccgggagctgcaggccatggcagaacaactggcggaaaattaccac aacacgtggggaaggaagaagaagcaggagctggaagccaaaggcggtgggacccacccc ctgctggtcccctacgacacgctaacagccaaggagaaggcacgagatcgagagaaggcc caggagctgctgaaattcctgcagatgaatggctacgcggttacaagaggccttaaggac atggaactggactcatcttccattgaaaagcggtttgcctttggcttcctgcagcagctg ctgcgctggatggacatttctcaggagttcattgcccacctggaggctgtggtcagcagt gggcgagtggaaaagtccccacatgaacaggagattaaattctttgccaagatcctgctc cctttgatcaaccagtacttcaccaaccactgcctctatttcttgtccactcctgctaaa gtgctgggcagtggcggccacgcctccaacaaggagaaggaaatgatcaccagcctcttc tgcaaacttgctgctcttgtccgccaccgagtctctctctttgggacggatgccccggct gtggttaactgtcttcacatcctggcccgctccctggatgccaggacggtgatgaagtca ggccctgagatcgtgaaggctggcctccgctccttcttcgagagtgcctcggaggacatc gagaagatggtggagaacctgcggctgggcaaggtgtcacaggcgcgcacccaggtgaag ggcgtgggccagaacctcacctacaccaccgtggcgctgctgccggtcctcaccaccctc ttccagcacatcgcccagcaccagttcggagatgacgtcattctggacgacgtccaggtc tcttgctaccgaacgctgtgcagtatctactccctgggaaccaccaagaacatttacgtg gaaaagcttcggccagcccttggggagtgcctggcccgtctggcagcagccatgccggtg gcgttcctggagccccagctgaacgagtacaacgcctgctccgtgtacaccaccaagtct ccccgagagcgggccatcctggggctccccaacagtgtggaggagatgtgtcctgacatc ccggtgctggagcggctcatggcagacatcggggggctggccgagtcaggggcccgctac acagagatgccgcacgtcattgagatcacgctgcccatgctatgcagctacctgccccga tggtgggagcgcgggcccgaggcaccccctcctgccctgcccgccggcgcccccccaccc tgcacagctgtcacctctgaccacctcaactccctgctggggaatatcctgagaatcatc gtcaacaacctgggcattgacgaggcctcctggatgaagcggctggctgtgttcgcacag cccatcgtgagccgtgcgcggccggagctcctgcagtcccacttcatccccaccatcggg cggctgcgcaagagggcggggaaggtggtgtccgaggaggagcagctgcggctggaggcc aaggccgaggcccaggagggcgagctgctggtgcgagacgagttctccgtgctctgccgg gacctgtacgccctgtatccgctgctcatccgctatgtggacaacaacagggcacagtgg ctgacggagccgaatcccagcgcggaggagctgttcaggatggtgggcgagatcttcatc tactggtccaagtcccataacttcaagcgcgaggagcagaactttgtggtccagaacgag atcaacaacatgtccttcctgactgcggacaacaagagcaaaatggctaaggcgggagat acacagtccggtggctcggaccaggaacgcacgaagaagaagcgccgcggggaccggtac tccgtgcagacgtcgctgatcgtggccacgctgaagaagatgctgcccatcggcctgaac atgtgcgcgcccaccgaccaggacctcatcacgctggccaagacccgctacgccctgaaa gacacagatgaggaggtccgggaatttctgaacaacaaccttcaccttcagggaaaggtc gaaggctccccgtctctgcgctggcagatggccctgtaccggggcgtcccaggtcgtgag gaggacgccgacgaccccgagaaaatcgtgcgcagagtccaggaagtgtcagccgtgctc tactacctggaccagaccgagcacccttacaagtctaagaaggccgtgtggcacaagctt ttgtccaagcagcgccggcgggcagtcgtggcctgtttccgtatgacgcccctgtacaac ctgcccacgcaccgggcatgtaacatgttcctggagagctacaaggctgcatggatcctg accgaagaccacagttttgaggaccgcatgatagatgacctttcaaaagctggggagcag gaggaggaggaggaagaggtggaagaaaagaagccagaccccctgcaccagttggtcctg cacttcagccgcactgccctgacggaaaagagcaaactggacgaggattacctgtacatg gcctatgctgatatcatggcaaagagctgccacctggaggagggaggggagaacggcgaa ggtgaagaggaggttgaggtctcctttgaggagaaagagatggagaagcagcggctccta taccagcaagcacggctgcacacccggggggcagccgagatggtgctgcagatgatcagt gcctgcaaaggagagacaggtgccatggtgtcctccaccctgaagctgggcatctccatc ctcaatggaggcaatgctgaggtccagcagaaaatgctggattatcttaaggacaagaag gaagttggcttcttccagagtatccaggcactgatgcaaacatgcagcgtactggatctc aatgcctttgagagacagaacaaggccgaggggctgggcatggtgaacgaggatggcact gtcatcaatcgccagaacggagagaaggtcatggcggatgatgaattcacacaagacctg ttccgattcctacaattgctctgtgaggggcacaataatgatttccagaactacctacgg acacagacagggaacacgaccactattaacatcatcatctgcacggtggactacctcctg cggctgcaggaatccatcagcgacttctactggtactactcaggcaaggatgtcattgaa gagcagggcaagaggaacttctccaaagccatgtccgtggctaagcaggtgttcaacagc ctcactgagtacatccagggtccctgcaccgggaaccagcagagcctggcgcacagccgc ctttgggacgcagtggtgggattcctgcacgtgttcgcccacatgatgatgaagctcgct caggactcaagccagatcgagctgctgaaggagctgctggatctgcagaaggacatggtg gtgatgttgctgtcgctactagaagggaacgtggtaaacggcacgatcgcccggcagatg gtggacatgctcgtggaatcctcgtccaatgtggagatgatcctcaagttctttgacatg ttcctgaaactcaaggacattgtgggctctgaagccttccaggactacgtaacggatccc cgtggcctcatctccaagaaggacttccagaaggccatggacagccagaagcagttcagc ggtccagaaatccagttcctgctttcgtgctccgaagcggatgagaacgagatgatcaac tgcgaggagttcgccaaccgcttccaggagccagctcgcgacatcggcttcaacgtggcg gtgctgctgaccaacctgtcggagcatgtgccgcatgacccgcgcctgcacaacttcctg gagctggccgagagcatcctcgagtacttccgcccctacctgggccgcatcgagatcatg ggcgcctcgcgccgcatcgagcgcatctacttcgagatctcggagaccaaccgcgcccag tgggagatgccccaggtgaaggagtccaagcgccagttcatcttcgacgtggtgaacgag ggcggcgaggccgagaagatggagctcttcgtgagtttctgcgaggacaccatcttcgag atgcagatcgccgcgcagatctcggagcccgagggcgagccggagaccgacgaggacgag ggcgcggcggaggcgggcgtggagggcgcggaggagagcgcggcgggccccgagggcacg gcggccacggcggcggcaggggcgacagcgcgggtggcggcggccatgggccgggccctg cgcggcctcagctaccgcagcctgcggcggcgcgtgcggcggctgcggcggctcacggcc cgcgaggcggccaccgcggtggcggcgctgctctgggcagccgtgacgcgcgcgggggcc gctggcgcgggggcggcggcgggcgcgctgggcctgctctggggctcgctgttcggcggc ggcctggtggagggcgccaagaaggtgacagtgaccgagctcctggcgggcatgcccgac cccaccagcgacgaggtgcacggcgagcagccggccgggcccggcggagacgcagacggc gagggtgccagcgaaggcgcaggggacgccgcggagggcgctggagacgaggaggaggcg gtggacgaggccgggccgggcggcgccgacggggcggtggccgtgacggatgggggcccc ttccggcccgaaggggctggcggtctcggggacatgggggacacgacgcctgcggaaccg cccacgcccgagggctctcccattctcaagaggaagctgggggtggatggagtggaggag gagctcccgccggagccggagccggaaccagaactggagccggagaaagcagatgccgag aatggggagaaagaagaagttcccgaacccccaccagagccccccaagaagcaagcacct ccctcaccccctccaaagaaggaagaagctgggggtgaattctggggagaactggaggtg cagagggtgaagttcctgaactacctgtcccggaacttttacaccctgcggttccttgcc ctcttcttggcatttgccatcaacttcatcttgctgttttataaggtctcagactctcca ccaggggaagacgacatggaaggctcagctgctggggacgtgtcaggtgcaggctctggt ggcggctctggctggggcttgggggccggagaggaggcagagggcgatgaggatgagaac atggtgtactacttcctggaggagagcacaggctacatggagcccgccctgcggtgtctg agcctcctgcatacactggtggcctttctctgcatcattggctataactgtctcaaggtg cccctggtaatctttaagcgggagaaggagctggcccggaagctggagtttgacggccta tacatcacagagcagcccgaggacgatgacgtgaaggggcagtgggaccgactggtgctc aacacaccgtctttccccagcaactactgggacaagtttgtcaagcgcaaggtcctggac aaacatggggacatctacgggcgggagcggattgctgagctactgggcatggacctggcc acactagagatcaccgcccacaatgagcgcaagcccgacccgccaccagggctgctgacc tggctcatgtccatcgatgtcaagtaccagatctggaagttcggggtcatcttcacagac aactccttcctgtacctgggctggtatatggtgatgtccctcttggggcactacaacaac ttcttcttcgctgcccatctcctggacatcgccatgggggtcaagacgctgcgcaccatc ctctcctccgtcacccacaatgggaaacagctggtgatgaccgtgggccttctggcggtg gtcgtctacctgtacaccgtagtggccttcaacttcttccgcaagttctacaacaagagc gaggatgaggatgagcctgacatgaaatgtgacgacatgatgacgtgttacctgtttcac atgtaa

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