Entry
Name
ABC transporters - Aliarcobacter faecis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Aliarcobacter faecis [GN:
afc ]
Gene
AFAEC_2296 cysT; sulfate ABC transporter CysATW, permease protein CysT [KO:K02046 ]
AFAEC_2297 cysW; sulfate ABC transporter CysATW, permease protein CysW [KO:K02047 ]
AFAEC_2271 aliphatic sulfonate ABC transporter, periplasmic substrate-binding protein [KO:K15553 ]
AFAEC_2276 aliphatic sulfonate ABC transporter, periplasmic substrate-binding protein [KO:K15553 ]
AFAEC_0013 modA; molybdenum ABC transporter ModABC, periplasmic molybdate-binding protein [KO:K02020 ]
AFAEC_0011 modB; molybdenum ABC transporter ModABC, permease protein [KO:K02018 ]
AFAEC_0293 iron(III)/spermidine/putrescine ABC transporter, periplasmic substrate-binding protein [KO:K02012 ]
AFAEC_0292 iron(III)/spermidine/putrescine ABC transporter, permease protein [KO:K02011 ]
AFAEC_0924 mlaC; lipid asymmetry ABC transporter MlaABCDEF, periplasmic component MlaC [KO:K07323 ]
AFAEC_2136 mlaD; lipid asymmetry ABC transporter MlaABCDEF, periplasmic component MlaD [KO:K02067 ]
AFAEC_2134 mlaE; lipid asymmetry ABC transporter MlaABCDEF, permease component MlaE [KO:K02066 ]
AFAEC_2135 mlaF; lipid asymmetry ABC transporter MlaABCDEF, ATPase component MlaF [KO:K02065 ]
AFAEC_2153 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
AFAEC_2151 pstA; phosphate ABC transporter, permease protein (DUF3333 domain) [KO:K02038 ]
AFAEC_1750 metal ion ABC transporter, periplasmic metal-binding protein [KO:K09815 ]
AFAEC_1085 cbiM; cobalt/nickel ECF transporter CbiMNQO, S component CbiM [KO:K02007 ]
AFAEC_1087 cbiQ; cobalt/nickel ECF transporter CbiMNQO, T component CbiQ [KO:K02008 ]
AFAEC_1088 cbiO; cobalt/nickel ECF transporter CbiMNQO, A component, ATP-binding protein CbiO [KO:K02006 ]
AFAEC_1086 cbiN; cobalt/nickel ECF transporter CbiMNQO, S component CbiN [KO:K16915 ]
AFAEC_0159 lptF; lipooligosaccharide transport system, ABC transporter permease component LptF [KO:K07091 ]
AFAEC_1575 lptG; lipooligosaccharide transport system, ABC transporter permease component LptG [KO:K11720 ]
AFAEC_1099 lptB; lipooligosaccharide transport system, ABC transporter ATP-binding component LptB [KO:K06861 ] [EC:7.5.2.5 ]
AFAEC_1894 ABC transporter, ATP-binding/permease components [KO:K14698 ] [EC:7.-.-.-]
AFAEC_1895 ABC transporter, ATP-binding/permease components [KO:K14699 ] [EC:7.-.-.-]
AFAEC_0710 macB; macrolide-specific efflux protein, ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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