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Entry
Name
ABC transporters - Achromobacter xylosoxidans NBRC 15126 = ATCC 27061
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Achromobacter xylosoxidans NBRC 15126 = ATCC 27061 [GN:
axn ]
Gene
AX27061_4815 Hydroxymethylpyrimidine ABC transporter, substrate-binding component [KO:K15553 ]
AX27061_2119 ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component [KO:K15553 ]
AX27061_2177 ABC-type nitrate/sulfonate/bicarbonate transport system periplasmic component-like protein [KO:K15553 ]
AX27061_2176 binding-protein-dependent transport systems inner membrane component [KO:K15554 ]
AX27061_4615 Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA [KO:K02020 ]
AX27061_0635 Putative ABC transporter, periplasmmic iron binding protein precursor [KO:K02012 ]
AX27061_2758 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
AX27061_0140 Glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein [KO:K05813 ]
AX27061_0139 Multiple sugar ABC transporter, membrane-spanning permease protein MsmF [KO:K05814 ]
AX27061_0138 Inner membrane component of binding-protein-dependent transport system [KO:K05815 ]
AX27061_4785 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS [KO:K02040 ]
AX27061_5301 Phosphonate ABC transporter phosphate-binding periplasmic component [KO:K02044 ]
AX27061_4894 Phosphonate ABC transporter phosphate-binding periplasmic component [KO:K02044 ]
AX27061_5060 ABC-type amino acid transport/signal transduction system, periplasmic component [KO:K02424 ]
AX27061_5796 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
AX27061_5809 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_5476 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_3867 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_3882 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_3719 High-affinity leucine-specific transport system, periplasmic binding protein LivK [KO:K01999 ]
AX27061_5539 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_4270 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_4949 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_5595 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_1769 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_2675 putative branched-chain amino acid ABC transporter (substrate-binding protein) [KO:K01999 ]
AX27061_2750 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
AX27061_2293 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_2761 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
AX27061_2777 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_0751 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_0981 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_0131 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_0676 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_1415 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_1425 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_1483 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
AX27061_5631 Branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
AX27061_5797 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_5806 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_6003 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_3881 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_3721 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_4271 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_5285 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_5596 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_5632 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_2676 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_2762 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_0750 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_0457 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_0980 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_0546 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_0586 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_1416 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_1424 High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997 ]
AX27061_3718 high-affinity branched-chain amino acid transport ATP-binding protein [KO:K01996 ]
AX27061_3202 ABC-type branched-chain amino acid transport system, ATPase component [KO:K11963 ]
AX27061_1509 Dipeptide-binding ABC transporter, periplasmic substrate-binding component [KO:K13889 ]
AX27061_1413 Transmembrane component BioN of energizing module of biotin ECF transporter [KO:K16783 ]
AX27061_1412 ATPase component BioM of energizing module of biotin ECF transporter [KO:K16784 ] [EC:7.6.2.-]
AX27061_2745 Capsular polysaccharide export system inner membrane protein KpsE [KO:K10107 ]
AX27061_3701 Lipoprotein releasing system ATP-binding protein LolD [KO:K09810 ] [EC:7.6.2.-]
AX27061_2240 Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [KO:K02195 ]
AX27061_2255 Cytochrome c-type biogenesis protein CcmC, putative heme lyase for CcmE [KO:K02195 ]
AX27061_2241 ABC transporter involved in cytochrome c biogenesis, CcmB subunit [KO:K02194 ]
AX27061_2256 ABC transporter involved in cytochrome c biogenesis, CcmB subunit [KO:K02194 ]
AX27061_2032 ABC transporter, transmembrane region:ABC transporter:Peptidase C39, bacteriocin processing [KO:K12541 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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