KEGG   PATHWAY: bah02010
Entry
bah02010                    Pathway                                
Name
ABC transporters - Bacillus anthracis CDC 684
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
bah02010  ABC transporters
bah02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Bacillus anthracis CDC 684 [GN:bah]
Gene
BAMEG_1683  putative sulfonate ABC transporter, sulfonate-binding protein [KO:K15553]
BAMEG_1684  putative sulfonate ABC transporter, permease protein [KO:K15554]
BAMEG_1682  putative sulfonate ABC transporter, ATP-binding protein [KO:K15555] [EC:7.6.2.14]
BAMEG_3831  putative ABC transporter, substrate-binding protein [KO:K15598]
BAMEG_3832  putative ABC transporter, permease protein [KO:K15599]
BAMEG_3833  ABC transporter, ATP-binding protein [KO:K15600]
BAMEG_0236  modA; molybdenum ABC transporter, molybdenum-binding protein [KO:K02020]
BAMEG_0234  modB; molybdenum ABC transporter, permease protein [KO:K02018]
BAMEG_5547  putative lipoprotein [KO:K02012]
BAMEG_2852  putative ABC transporter, substrate-binding protein [KO:K02012]
BAMEG_3260  putative iron compound ABC transporter, iron compound-binding protein [KO:K02012]
BAMEG_2851  putative ABC transporter, permease protein [KO:K02011]
BAMEG_3257  putative iron compound ABC transporter, permease protein [KO:K02011]
BAMEG_2853  ABC transporter, ATP-binding protein [KO:K02010] [EC:7.2.2.7]
BAMEG_3258  ABC transporter, ATP-binding protein [KO:K02010] [EC:7.2.2.7]
BAMEG_3296  potD; spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein [KO:K11069]
BAMEG_3297  potC; spermidine/putrescine ABC transporter, permease protein [KO:K11070]
BAMEG_3298  potB; spermidine/putrescine ABC transporter, permease protein [KO:K11071]
BAMEG_3299  potA; spermidine/putrescine ABC transporter, ATP-binding protein [KO:K11072] [EC:7.6.2.11]
BAMEG_1809  putative glycine betaine/L-proline ABC transporter, glycine betaine/L-proline-binding protein [KO:K02002]
BAMEG_1811  glycine betaine/L-proline ABC transporter, permease protein [KO:K02001]
BAMEG_1810  proV2; glycine betaine/L-proline ABC transporter, ATP-binding protein [KO:K02000] [EC:7.6.2.9]
BAMEG_2313  glycine betaine/L-proline ABC transporter, permease and substrate-binding protein [KO:K05845 K05846]
BAMEG_2314  proV1; glycine betaine/L-proline ABC transporter, ATP-binding protein [KO:K05847] [EC:7.6.2.9]
BAMEG_4273  sugar ABC transporter, ATP-binding protein [KO:K10112] [EC:7.5.2.-]
BAMEG_4270  putative maltosaccharide ABC transporter, maltosaccharide-binding protein [KO:K15770]
BAMEG_4269  malC; maltosaccharide ABC transporter, permease protein [KO:K15771]
BAMEG_4268  malD; maltosaccharide ABC transporter, permease protein [KO:K15772]
BAMEG_0702  lipoprotein, Bmp family [KO:K07335]
BAMEG_0705  sugar ABC transporter, permease protein [KO:K23535]
BAMEG_0706  sugar ABC transporter, permease protein [KO:K23536]
BAMEG_0703  sugar ABC transporter, ATP-binding protein [KO:K23537]
BAMEG_3917  rbsB; ribose ABC transporter, ribose-binding protein [KO:K10439]
BAMEG_3918  rbsC; ribose ABC transporter, permease protein [KO:K10440]
BAMEG_3919  rbsA; ribose ABC transporter, ATP-binding protein [KO:K10441] [EC:7.5.2.7]
BAMEG_3920  rbsD; ribose ABC transporter protein [KO:K06726] [EC:5.4.99.62]
BAMEG_4017  putative glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein [KO:K05813]
BAMEG_4019  putative glycerol-3-phosphate ABC transporter, permease protein [KO:K05814]
BAMEG_4018  putative glycerol-3-phosphate ABC transporter, permease protein [KO:K05815]
BAMEG_4020  putative glycerol-3-phosphate ABC transporter, ATP-binding protein [KO:K05816] [EC:7.6.2.10]
BAMEG_4533  phoX; phosphate ABC transporter, phosphate-binding protein [KO:K02040]
BAMEG_3871  putative phosphate ABC transporter, phosphate-binding protein [KO:K02040]
BAMEG_4532  pstC; phosphate ABC transporter, permease protein [KO:K02037]
BAMEG_3869  putative phosphate ABC transporter, permease protein [KO:K02037]
BAMEG_4531  pstA; phosphate ABC transporter, permease protein [KO:K02038]
BAMEG_3868  putative phosphate ABC transporter, permease protein [KO:K02038]
BAMEG_4530  pstB; phosphate ABC transporter, ATP-binding protein [KO:K02036] [EC:7.3.2.1]
BAMEG_0886  putative phosphonate ABC transporter, phosphonate-binding protein [KO:K02044]
BAMEG_0888  phosphonate ABC transporter, permease protein [KO:K02042]
BAMEG_0889  phosphonate ABC transporter, permease protein [KO:K02042]
BAMEG_0887  phosphonate ABC transporter, ATP-binding protein [KO:K02041] [EC:7.3.2.2]
BAMEG_3947  amino acid ABC transporter, amino acid-binding protein [KO:K10039]
BAMEG_3946  amino acid ABC transporter, permease protein [KO:K10040]
BAMEG_3945  amino acid ABC transporter, permease protein [KO:K10040]
BAMEG_3948  amino acid ABC transporter, ATP-binding protein [KO:K10041] [EC:7.4.2.1]
BAMEG_3704  amino acid ABC transporter, amino acid-binding protein [KO:K02424]
BAMEG_3703  amino acid ABC transporter, permease protein [KO:K10009]
BAMEG_3702  amino acid ABC transporter, ATP-binding protein [KO:K10010] [EC:7.4.2.1]
BAMEG_4413  amino acid ABC transporter, amino acid-binding protein [KO:K23059]
BAMEG_4412  amino acid ABC transporter, permease protein [KO:K17077]
BAMEG_4411  amino acid ABC transporter, ATP-binding protein [KO:K23060] [EC:7.4.2.1]
BAMEG_2659  putative branched-chain amino acid ABC transporter, branched chain amino acid-binding protein [KO:K01999]
BAMEG_2656  branched-chain amino acid ABC transporter, permease protein [KO:K01997]
BAMEG_2655  branched-chain amino acid ABC transporter, permease protein [KO:K01998]
BAMEG_2658  branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
BAMEG_2657  branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
BAMEG_0372  putative ABC transporter, substrate-binding protein [KO:K02073]
BAMEG_5275  putative ABC transporter, substrate-binding protein [KO:K02073]
BAMEG_5276  putative ABC transporter, substrate-binding protein [KO:K02073]
BAMEG_0207  putative ABC transporter, substrate-binding protein [KO:K02073]
BAMEG_0371  ABC transporter, permease protein [KO:K02072]
BAMEG_5277  ABC transporter, permease protein [KO:K02072]
BAMEG_0205  ABC transporter, permease protein [KO:K02072]
BAMEG_0370  ABC transporter, ATP-binding protein [KO:K02071]
BAMEG_5278  ABC transporter, ATP-binding protein [KO:K02071]
BAMEG_0206  ABC transporter, ATP-binding protein [KO:K02071]
BAMEG_3397  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_0990  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_1748  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_0988  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_0222  oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_0227  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_0991  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_2724  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_2761  ABC transporter, solute binding protein [KO:K15580]
BAMEG_2549  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BAMEG_B0092  oligopeptide ABC transporter [KO:K15580]
BAMEG_3396  oligopeptide ABC transporter, permease protein [KO:K15581]
BAMEG_3395  oligopeptide ABC transporter, permease protein [KO:K15582]
BAMEG_3394  oligopeptide ABC transporter, ATP-binding protein [KO:K15583]
BAMEG_3393  oligopeptide ABC transporter, ATP-binding protein [KO:K10823]
BAMEG_4800  iron compound ABC transporter, iron compound-binding protein [KO:K23227]
BAMEG_4801  iron compound ABC transporter, permease protein [KO:K23228]
BAMEG_1423  mntA; manganese ABC transporter, manganese-binding protein [KO:K19975]
BAMEG_1422  metal ABC transporter, permease protein [KO:K19976]
BAMEG_1421  metal ABC transporter, ATP-binding protein [KO:K19973] [EC:7.2.2.5]
BAMEG_2555  putative adhesion lipoprotein [KO:K09815]
BAMEG_A0190  putative zinc-binding lipoprotein AdcA [KO:K09815]
BAMEG_4542  putative cation ABC transporter, permease protein [KO:K09816]
BAMEG_4543  putative cation ABC transporter, ATP-binding protein [KO:K09817] [EC:7.2.2.20]
BAMEG_5207  bioY family protein [KO:K03523]
BAMEG_0944  bioY family protein [KO:K03523]
BAMEG_1949  cobalt transport protein [KO:K16785]
BAMEG_0157  cobalt transport protein [KO:K16785]
BAMEG_1260  ABC transporter, permease protein [KO:K16785]
BAMEG_0155  ABC transporter, ATP-binding protein [KO:K16786] [EC:7.-.-.-]
BAMEG_0156  ABC transporter, ATP-binding protein [KO:K16787] [EC:7.-.-.-]
BAMEG_1630  putative sugar ABC transporter, sugar-binding protein [KO:K10555]
BAMEG_1628  putative ribose ABC transporter, permease protein [KO:K10556]
BAMEG_1629  putative ribose ABC transporter, permease protein [KO:K10557]
BAMEG_1626  putative ribose ABC transporter, ATP-binding protein [KO:K10558]
BAMEG_5557  putative techoic acid ABC transporter, efflux permease [KO:K09692]
BAMEG_5556  techoic acid ABC transporter, ATP-binding protein [KO:K09693] [EC:7.5.2.4]
BAMEG_1362  putative ABC transporter, permease protein [KO:K09813]
BAMEG_1363  ABC transporter, ATP-binding protein [KO:K09814] [EC:7.6.2.-]
BAMEG_0337  putative bacitracin ABC transporter, permease protein [KO:K19310]
BAMEG_0338  putative bacitracin ABC transporter, ATP-binding protein [KO:K19309]
BAMEG_5118  efflux ABC transporter, permease protein [KO:K11632]
BAMEG_5119  efflux ABC transporter, ATP-binding protein [KO:K11631]
BAMEG_0729  putative bacteriocin ABC transporter, permease protein subunit [KO:K20491]
BAMEG_0730  putative bacteriocin ABC transporter, permease protein subunit [KO:K20492]
BAMEG_0728  putative bacteriocin ABC transporter, ATP-binding protein [KO:K20490]
BAMEG_5467  ftsX; cell division ABC transporter, permease protein FtsX [KO:K09811]
BAMEG_5468  ftsE; cell division ABC transporter, ATP-binding protein FtsE [KO:K09812]
BAMEG_4340  putative membrane protein [KO:K16919]
BAMEG_4339  ABC transporter, ATP-binding protein [KO:K16921]
BAMEG_3707  ABC transporter, permease/ATP-binding protein [KO:K18889]
BAMEG_0894  ABC transporter, permease/ATP-binding protein [KO:K18889]
BAMEG_0895  ABC transporter, permease/ATP-binding protein [KO:K18890]
BAMEG_3706  ABC transporter, permease/ATP-binding protein [KO:K18890]
BAMEG_2636  multidrug resistance ABC transporter ATP-binding and permease protein [KO:K18104] [EC:7.6.2.2]
BAMEG_2157  ABC transporter, permease/ATP-binding protein [KO:K18887]
BAMEG_2156  ABC transporter, permease/ATP-binding protein [KO:K18888]
BAMEG_2645  transport ATP-binding protein CydD [KO:K16012]
BAMEG_2646  transport ATP-binding protein CydC [KO:K16013]
BAMEG_1996  ABC transporter, ATP-binding protein [KO:K18231]
BAMEG_5462  putative macrolide efflux pump [KO:K18231]
BAMEG_2068  ABC transporter, ATP-binding protein [KO:K19350]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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