KEGG   PATHWAY: bal02010
Entry
bal02010                    Pathway                                
Name
ABC transporters - Bacillus cereus biovar anthracis CI
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
bal02010  ABC transporters
bal02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Bacillus cereus biovar anthracis CI [GN:bal]
Gene
BACI_c28770  ssuA; alkanesulfonates-binding protein [KO:K15553]
BACI_c28760  ssuC; alkanesulfonates transport system permease; sulfonate ABC transporter, permease [KO:K15554]
BACI_c28780  ssuB; alkanesulfonates transport ATP-binding protein [KO:K15555] [EC:7.6.2.14]
BACI_c07590  ABC transporter, substrate-binding protein [KO:K15598]
BACI_c07580  ABC transporter, permease [KO:K15599]
BACI_c07570  ABC transporter, ATP-binding protein [KO:K15600]
BACI_c02400  modA; molybdenum ABC transporter, substrate-binding protein [KO:K02020]
BACI_c02390  modB; molybdenum ABC transporter, permease [KO:K02018]
BACI_c13560  afuA1; ABC transporter, solute-binding protein [KO:K02012]
BACI_c17380  ABC transporter, substrate-binding protein [KO:K02012]
BACI_c52530  possible ABC transporter, substrate-binding protein [KO:K02012]
BACI_c13590  afuB; ABC transporter, permease; possible iron transporter [KO:K02011]
BACI_c17390  ABC transporter, permease protein, putative [KO:K02011]
BACI_c13580  ABC transporter, ATP-binding protein [KO:K02010] [EC:7.2.2.7]
BACI_c17370  ABC transporter, ATP-binding protein [KO:K02010] [EC:7.2.2.7]
BACI_c13220  potD; spermidine/putrescine ABC transporter, spermidine/putrescine-binding protein [KO:K11069]
BACI_c13210  potC; spermidine/putrescine ABC transporter, permease [KO:K11070]
BACI_c13200  potB; spermidine/putrescine ABC transporter, permease [KO:K11071]
BACI_c13190  potA; spermidine/putrescine ABC transporter, ATP-binding protein [KO:K11072] [EC:7.6.2.11]
BACI_c27510  opuAC; glycine betaine-binding protein [KO:K02002]
BACI_c27490  opuAB; glycine betaine/L-proline ABC transporter, permease [KO:K02001]
BACI_c27500  opuAA; glycine betaine/L-proline ABC transporter, ATP-binding protein [KO:K02000] [EC:7.6.2.9]
BACI_c22430  opuBB; glycine betaine/choline ABC transporter, ATP-binding protein [KO:K05845 K05846]
BACI_c22420  opuCA; glycine betaine ABC transporter, ATP-binding protein [KO:K05847] [EC:7.6.2.9]
BACI_c39780  sugar ABC transporter, ATP-binding protein [KO:K10112] [EC:7.5.2.-]
BACI_c39720  maltose-maltodextrin ABC-related solute binding protein [KO:K15770]
BACI_c39710  malC; maltosaccharide ABC transporter, permease [KO:K15771]
BACI_c39700  malD; maltosaccharide ABC transporter, permease [KO:K15772]
BACI_c37420  lipoprotein, Bmp family [KO:K07335]
BACI_c37400  branched-chain amino acid transport system, permease component [KO:K23535]
BACI_c37390  branched-chain amino acid transport system, permease component [KO:K23536]
BACI_c37410  ABC transporter, ATP-binding protein, C-terminal part [KO:K23537]
BACI_c06790  rbsB; ribose ABC transporter, ribose-binding protein [KO:K10439]
BACI_c06780  rbsC; ribose ABC transporter, permease [KO:K10440]
BACI_c06770  rbsA; ribose ABC transporter, ATP-binding protein [KO:K10441] [EC:7.5.2.7]
BACI_c06760  rbsD; ribose ABC transporter, permease [KO:K06726] [EC:5.4.99.62]
BACI_c05790  probable glycerol-3-phosphate ABC transporter, glycerol-3-phosphate-binding protein [KO:K05813]
BACI_c05760  probable glycerol-3-phosphate ABC transporter, permease [KO:K05814]
BACI_c05770  probable glycerol-3-phosphate ABC transporter, permease [KO:K05815]
BACI_c05740  ABC transporter; probable glycerol-3-phosphate ABC transporter, ATP-binding protein [KO:K05816] [EC:7.6.2.10]
BACI_c07240  pstS1; phosphate ABC transporter, phosphate-binding protein [KO:K02040]
BACI_c42420  pstS2; phosphate ABC transporter, phosphate-binding protein [KO:K02040]
BACI_c07250  pstC1; phosphate ABC transporter, permease [KO:K02037]
BACI_c42410  pstC2; phosphate ABC transporter, permease [KO:K02037]
BACI_c07260  pstA1; phosphate ABC transporter, permease [KO:K02038]
BACI_c42400  pstA2; phosphate ABC transporter, permease [KO:K02038]
BACI_c42390  pstB; phosphate ABC transporter, ATP-binding protein [KO:K02036] [EC:7.3.2.1]
BACI_c36360  phosphonate ABC transporter, phosphonate-binding protein, putative [KO:K02044]
BACI_c36330  phosphonate ABC transporter, permease [KO:K02042]
BACI_c36340  phosphonate ABC transporter, permease [KO:K02042]
BACI_c36350  phosphonate ABC transporter, ATP-binding protein [KO:K02041] [EC:7.3.2.2]
BACI_c06530  glnH; ABC transporter, substrate-binding protein; probable glutamine-binding protein [KO:K10039]
BACI_c06550  glnP2; ABC transporter, permease; probable glutamine ABC transporter, permease [KO:K10040]
BACI_c06540  glnP1; ABC transporter, permease; probable glutamine ABC transporter, permease [KO:K10040]
BACI_c06520  glnQ2; ABC transporter, ATP-binding protein; probable glutamine ABC transporter, ATP-binding [KO:K10041] [EC:7.4.2.1]
BACI_c09000  amino acid ABC transporter, amino acid-binding protein [KO:K02424]
BACI_c09010  amino acid ABC transporter, permease [KO:K10009]
BACI_c09020  amino acid ABC transporter, ATP-binding protein [KO:K10010] [EC:7.4.2.1]
BACI_c41210  amino acid ABC transporter, amino acid-binding protein [KO:K23059]
BACI_c41200  amino acid ABC transporter, permease [KO:K17077]
BACI_c41190  amino acid ABC transporter, ATP-binding protein [KO:K23060] [EC:7.4.2.1]
BACI_c19090  branched-chain amino acid ABC transporter, substrate-binding protein [KO:K01999]
BACI_c19120  livH; branched-chain amino acid ABC transporter, permease [KO:K01997]
BACI_c19130  livM; branched chain amino acid ABC transporter, permease [KO:K01998]
BACI_c19100  livG; branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995]
BACI_c19110  livF; branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996]
BACI_c02130  ABC transporter, substrate-binding protein [KO:K02073]
BACI_c03590  ABC transporter, substrate-binding protein [KO:K02073]
BACI_c49900  ABC transporter, substrate-binding protein [KO:K02073]
BACI_c49910  ABC transporter, substrate-binding protein [KO:K02073]
BACI_c02110  ABC transporter, permease protein [KO:K02072]
BACI_c03580  ABC transporter, permease [KO:K02072]
BACI_c49920  ABC transporter, permease [KO:K02072]
BACI_c02120  ABC transporter, ATP-binding protein [KO:K02071]
BACI_c03570  ABC transporter, ATP-binding protein [KO:K02071]
BACI_c49930  ABC transporter, ATP-binding protein [KO:K02071]
BACI_c02330  oppA2; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c12170  oppA8; oligopeptide ABC transporter, oligopeptide-binding protein, N-terminal domain protein [KO:K15580]
BACI_c20030  oppA12; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c35270  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c28160  oppA13; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c18550  oppA11; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c02280  oppA1; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c18190  oppA10; oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c35260  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_c35310  putative oligopeptide ABC transporter, oligopeptide-binding protein [KO:K15580]
BACI_pCIXO200880  extracellular solute-binding protein family 5 [KO:K15580]
BACI_c12190  oppB6; oligopeptide ABC transporter, permease [KO:K15581]
BACI_c12200  oppC6; oligopeptide ABC transporter, permease [KO:K15582]
BACI_c12210  oppD5; oligopeptide ABC transporter, ATP-binding protein [KO:K15583]
BACI_c12220  oppF5; oligopeptide ABC transporter, ATP-binding protein [KO:K10823]
BACI_c31370  adhesion lipoprotein [KO:K19975]
BACI_c31380  ABC transporter, permease protein [KO:K19976]
BACI_c31390  ABC transporter, ATP-binding protein [KO:K19973] [EC:7.2.2.5]
BACI_c19970  znuA; high-affinity zinc uptake system periplasmic-binding protein [KO:K09815]
BACI_pCIXO101830  zinc-binding lipoprotein adca domain protein [KO:K09815]
BACI_c42510  ABC transporter, permease, family 3 [KO:K09816]
BACI_c42520  ABC transporter, ATP-binding protein [KO:K09817] [EC:7.2.2.20]
BACI_c35770  bioY family protein [KO:K03523]
BACI_c49250  bioY; biotin synthesis BioY protein [KO:K03523]
BACI_c26170  cbiQ; ABC transporter, permease; cobalt transport protein [KO:K16785]
BACI_c01680  ABC transporter; possible cobalt transport protein [KO:K16785]
BACI_c32630  putative Cobalt transport protein [KO:K16785]
BACI_c01660  ABC transporter, ATP-binding protein [KO:K16786] [EC:7.-.-.-]
BACI_c01670  ABC transporter, ATP-binding protein [KO:K16787] [EC:7.-.-.-]
BACI_c29300  sugar ABC transporter, sugar-binding protein [KO:K10555]
BACI_c29320  sugar ABC transporter, permease [KO:K10556]
BACI_c29310  sugar ABC transporter, permease [KO:K10557]
BACI_c29330  sugar ABC transporter, ATP-binding protein [KO:K10558]
BACI_c52630  techoic acid ABC transporter, efflux permease, putative [KO:K09692]
BACI_c52620  polysaccharide ABC transporter, ATP-binding protein [KO:K09693] [EC:7.5.2.4]
BACI_c31980  predicted permease [KO:K09813]
BACI_c31970  ABC transporter related, ATP-binding protein [KO:K09814] [EC:7.6.2.-]
BACI_c48210  ABC transporter permease protein [KO:K11632]
BACI_c48310  ABC transporter, permease [KO:K11632]
BACI_c51020  putative permease [KO:K11632]
BACI_c51010  putative ABC transporter, ATP-binding protein [KO:K11631]
BACI_c48220  ABC transporter, ATP-binding protein [KO:K11631]
BACI_c48320  ABC transporter, ATP-binding protein [KO:K11631]
BACI_c10390  mrsG; ABC transporter, permease; possible MrsG protein [KO:K20460]
BACI_c10400  mrsE; permease; possible MrsE protein [KO:K20461]
BACI_c10380  mrsF; ABC transporter, ATP-binding protein; probable MrsF protein [KO:K20459]
BACI_c37160  predicted transporter protein [KO:K20491]
BACI_c37150  putative permease [KO:K20492]
BACI_c37170  predicted ABC transporter, ATPase component [KO:K20490]
BACI_c51700  ftsX; cell division ABC transporter, permease [KO:K09811]
BACI_c51710  ftsE; cell division ABC transporter, ATP-binding protein [KO:K09812]
BACI_c40460  conserved membrane protein [KO:K16919]
BACI_c40450  ABC transporter, ATP-binding protein [KO:K16921]
BACI_c36290  C-terminal part of ATP-binding/permease protein [KO:K18889]
BACI_c08980  multidrug ABC transporter, ATP-binding protein and permease [KO:K18889]
BACI_c08990  multidrug resistance ABC transporter, ATP-binding protein and permease [KO:K18890]
BACI_c36280  ABC transporter, ATP-binding protein [KO:K18890]
BACI_c19310  multidrug resistance ABC transporter, ATP-binding and permease protein [KO:K18104] [EC:7.6.2.2]
BACI_c23850  multidrug resistance ABC transporter, ATP-binding and permease [KO:K18887]
BACI_c23860  multidrug resistance ABC transporter, ATP-binding and permease [KO:K18888]
BACI_c19230  cydC; transport ATP-binding protein [KO:K16012]
BACI_c19220  cydD; ABC transporter, ATP-binding and permease [KO:K16013]
BACI_c25790  expZ; ABC transporter, ATP-binding protein [KO:K18231]
BACI_c24990  transporter [KO:K19350]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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