KEGG   PATHWAY: bard02010
Entry
bard02010                   Pathway                                
Name
ABC transporters - Bacillus arachidis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
bard02010  ABC transporters
bard02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Bacillus arachidis [GN:bard]
Gene
QRY57_05535  ABC transporter substrate-binding protein [KO:K15598]
QRY57_05530  ABC transporter permease [KO:K15599]
QRY57_05525  ABC transporter ATP-binding protein [KO:K15600]
QRY57_02730  modA; molybdate ABC transporter substrate-binding protein [KO:K02020]
QRY57_02725  modB; molybdate ABC transporter permease subunit [KO:K02018]
QRY57_25665  ABC transporter substrate-binding protein [KO:K02012]
QRY57_08235  spermidine/putrescine ABC transporter substrate-binding protein [KO:K11069]
QRY57_08230  potC; spermidine/putrescine ABC transporter permease PotC [KO:K11070]
QRY57_08225  ABC transporter permease [KO:K11071]
QRY57_08220  potA; spermidine/putrescine ABC transporter ATP-binding protein PotA [KO:K11072] [EC:7.6.2.11]
QRY57_14175  glycine betaine ABC transporter substrate-binding protein [KO:K02002]
QRY57_14165  proline/glycine betaine ABC transporter permease [KO:K02001]
QRY57_14170  glycine betaine/L-proline ABC transporter ATP-binding protein [KO:K02000] [EC:7.6.2.9]
QRY57_12670  ABC transporter permease/substrate-binding protein [KO:K05845 K05846]
QRY57_12665  ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
QRY57_12735  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
QRY57_19865  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
QRY57_04770  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K10112] [EC:7.5.2.-]
QRY57_19845  extracellular solute-binding protein [KO:K15770]
QRY57_19840  ABC transporter permease subunit [KO:K15771]
QRY57_19835  malD; maltosaccharide ABC transporter permease MalD [KO:K15772]
QRY57_18620  BMP family protein [KO:K07335]
QRY57_18610  ABC transporter permease [KO:K23535]
QRY57_18605  ABC transporter permease [KO:K23536]
QRY57_18615  ABC transporter ATP-binding protein [KO:K23537]
QRY57_05140  rbsB; ribose ABC transporter substrate-binding protein RbsB [KO:K10439]
QRY57_05135  rbsC; ribose ABC transporter permease [KO:K10440]
QRY57_05130  sugar ABC transporter ATP-binding protein [KO:K10441] [EC:7.5.2.7]
QRY57_05125  rbsD; D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
QRY57_18070  ABC transporter substrate-binding protein [KO:K05813]
QRY57_04630  ABC transporter substrate-binding protein [KO:K05813]
QRY57_04620  sugar ABC transporter permease [KO:K05814]
QRY57_04625  carbohydrate ABC transporter permease [KO:K05815]
QRY57_04615  ugpC; sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC [KO:K05816] [EC:7.6.2.10]
QRY57_21105  PstS family phosphate ABC transporter substrate-binding protein [KO:K02040]
QRY57_05360  phosphate ABC transporter substrate-binding protein PstS family protein [KO:K02040]
QRY57_21100  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
QRY57_05365  pstC; phosphate ABC transporter permease subunit PstC [KO:K02037]
QRY57_21095  pstA; phosphate ABC transporter permease PstA [KO:K02038]
QRY57_05370  pstA; phosphate ABC transporter permease PstA [KO:K02038]
QRY57_21090  pstB; phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
QRY57_05030  glutamate ABC transporter substrate-binding protein [KO:K10039]
QRY57_05035  amino acid ABC transporter permease [KO:K10040]
QRY57_05040  amino acid ABC transporter permease [KO:K10040]
QRY57_05025  amino acid ABC transporter ATP-binding protein [KO:K10041] [EC:7.4.2.1]
QRY57_06090  amino acid ABC transporter substrate-binding protein [KO:K02424]
QRY57_06095  amino acid ABC transporter permease [KO:K10009]
QRY57_06100  amino acid ABC transporter ATP-binding protein [KO:K10010] [EC:7.4.2.1]
QRY57_20570  transporter substrate-binding domain-containing protein [KO:K23059]
QRY57_20565  amino acid ABC transporter permease [KO:K17077]
QRY57_20560  amino acid ABC transporter ATP-binding protein [KO:K23060] [EC:7.4.2.1]
QRY57_11000  substrate-binding domain-containing protein [KO:K01999]
QRY57_11015  branched-chain amino acid ABC transporter permease [KO:K01997]
QRY57_11020  branched-chain amino acid ABC transporter permease [KO:K01998]
QRY57_11005  ABC transporter ATP-binding protein [KO:K01995]
QRY57_11010  ABC transporter ATP-binding protein [KO:K01996]
QRY57_15410  MetQ/NlpA family ABC transporter substrate-binding protein [KO:K02073]
QRY57_24600  metQ; methionine ABC transporter substrate-binding lipoprotein MetQ [KO:K02073]
QRY57_24605  metQ; methionine ABC transporter substrate-binding lipoprotein MetQ [KO:K02073]
QRY57_15395  methionine ABC transporter permease [KO:K02072]
QRY57_24610  methionine ABC transporter permease [KO:K02072]
QRY57_03470  methionine ABC transporter permease [KO:K02072]
QRY57_15400  ATP-binding cassette domain-containing protein [KO:K02071]
QRY57_24615  methionine ABC transporter ATP-binding protein [KO:K02071]
QRY57_11375  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_14370  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_17570  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_17575  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_17580  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_07610  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_10475  peptide ABC transporter substrate-binding protein [KO:K15580]
QRY57_07615  ABC transporter permease [KO:K15581]
QRY57_07620  ABC transporter permease [KO:K15582]
QRY57_07625  ABC transporter ATP-binding protein [KO:K15583]
QRY57_07630  ATP-binding cassette domain-containing protein [KO:K10823]
QRY57_22290  iron-siderophore ABC transporter substrate-binding protein [KO:K23227]
QRY57_22295  fhuB; Fe(3+)-hydroxamate ABC transporter permease FhuB [KO:K23228]
QRY57_11345  metal ABC transporter substrate-binding protein [KO:K09815]
QRY57_21150  metal ABC transporter permease [KO:K09816]
QRY57_21155  metal ABC transporter ATP-binding protein [KO:K09817] [EC:7.2.2.20]
QRY57_17785  biotin transporter BioY [KO:K03523]
QRY57_24200  biotin transporter BioY [KO:K03523]
QRY57_24905  biotin transporter BioY [KO:K03523]
QRY57_13880  energy-coupling factor transporter transmembrane component T [KO:K16785]
QRY57_16105  energy-coupling factor transporter transmembrane component T [KO:K16785]
QRY57_02470  energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
QRY57_02460  energy-coupling factor ABC transporter ATP-binding protein [KO:K16786] [EC:7.-.-.-]
QRY57_02465  energy-coupling factor ABC transporter ATP-binding protein [KO:K16787] [EC:7.-.-.-]
QRY57_14945  lsrB; autoinducer 2 ABC transporter substrate-binding protein LsrB [KO:K10555]
QRY57_14955  sugar ABC transporter permease [KO:K10556]
QRY57_14950  autoinducer 2 import system permease LsrD [KO:K10557]
QRY57_14960  sugar ABC transporter ATP-binding protein [KO:K10558]
QRY57_25900  ABC transporter permease [KO:K09692]
QRY57_25895  tagH; teichoic acids export ABC transporter ATP-binding subunit TagH [KO:K09693] [EC:7.5.2.4]
QRY57_15475  ABC transporter permease [KO:K09813]
QRY57_18480  ABC transporter permease [KO:K09813]
QRY57_06305  ABC transporter permease [KO:K09813]
QRY57_15470  ABC transporter ATP-binding protein [KO:K09814] [EC:7.6.2.-]
QRY57_18485  ABC transporter ATP-binding protein [KO:K09814] [EC:7.6.2.-]
QRY57_06310  ABC transporter ATP-binding protein [KO:K09814] [EC:7.6.2.-]
QRY57_03230  ABC transporter permease [KO:K19310]
QRY57_03235  ABC transporter ATP-binding protein [KO:K19309]
QRY57_23780  ABC transporter permease [KO:K11632]
QRY57_00275  ABC transporter permease [KO:K11632]
QRY57_23785  ABC transporter ATP-binding protein [KO:K11631]
QRY57_00280  ABC transporter ATP-binding protein [KO:K11631]
QRY57_10415  ABC transporter permease [KO:K20461]
QRY57_10420  ABC transporter permease [KO:K20461]
QRY57_10425  ABC transporter ATP-binding protein [KO:K20459]
QRY57_25340  ftsX; permease-like cell division protein FtsX [KO:K09811]
QRY57_25345  ftsE; cell division ATP-binding protein FtsE [KO:K09812]
QRY57_20175  ABC-2 transporter permease [KO:K16919]
QRY57_20180  ABC transporter permease subunit [KO:K16919]
QRY57_20170  ABC transporter ATP-binding protein [KO:K16921]
QRY57_18160  ABC transporter transmembrane domain-containing protein [KO:K18889]
QRY57_06075  ABC transporter transmembrane domain-containing protein [KO:K18889]
QRY57_18155  ABC transporter ATP-binding protein [KO:K18890]
QRY57_06080  ABC transporter ATP-binding protein [KO:K18890]
QRY57_11075  ABC transporter ATP-binding protein [KO:K18104] [EC:7.6.2.2]
QRY57_06600  ABC transporter ATP-binding protein [KO:K18887]
QRY57_06595  ABC transporter ATP-binding protein [KO:K18888]
QRY57_00985  peptidase domain-containing ABC transporter [KO:K20344]
QRY57_10310  Vga family ABC-F type ribosomal protection protein [KO:K18231]
QRY57_13425  Lsa family ABC-F type ribosomal protection protein [KO:K19350]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
LinkDB

DBGET integrated database retrieval system