Entry Name ABC transporters - Beijerinckiaceae bacterium RH AL1
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Beijerinckiaceae bacterium RH AL1 [GN:
bbar ]
Gene RHAL1_02408 ssuA; alkanesulfonate transporter subunit; periplasmic-binding component of ABC superfamily protein [KO:K15553 ]
RHAL1_02411 ssuC; alkanesulfonate transport protein (ABC superfamily, membrane) [KO:K15554 ]
RHAL1_02410 ssuB_1; alkanesulfonate transporter subunit; ATP-binding component of ABC superfamily protein [KO:K15555 ] [EC:7.6.2.14 ]
RHAL1_04049 modA; molybdate transporter subunit; periplasmic-binding component of ABC superfamily protein [KO:K02020 ]
RHAL1_04050 modB; molybdate transporter subunit; membrane component of ABC superfamily protein [KO:K02018 ]
RHAL1_04027 potB; polyamine transporter subunit; membrane component of ABC superfamily protein [KO:K11071 ]
RHAL1_01234 malK; fused maltose transport subunit, ATP-binding component of ABC superfamily; regulatory protein [KO:K10111 ] [EC:7.5.2.-]
RHAL1_00626 ugpC; sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K10112 ] [EC:7.5.2.-]
RHAL1_01232 Sorbitol ABC transporter membrane protein / mannitol ABC transporter membrane protein [KO:K10228 ]
RHAL1_00802 xylH; D-xylose transporter subunit; membrane component of ABC superfamily protein [KO:K10547 ]
RHAL1_00801 xylG; fused D-xylose transporter subunits of ABC superfamily: ATP-binding components [KO:K10548 ] [EC:7.5.2.-]
RHAL1_02593 Phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein [KO:K02067 ]
RHAL1_03872 rbsC; D-ribose transporter subunit; membrane component of ABC superfamily protein [KO:K10440 ]
RHAL1_00914 pstS; phosphate transporter subunit; periplasmic-binding component of ABC superfamily protein [KO:K02040 ]
RHAL1_00913 pstC; phosphate transporter subunit; membrane component of ABC superfamily protein [KO:K02037 ]
RHAL1_00912 pstA; phosphate transporter subunit; membrane component of ABC superfamily protein [KO:K02038 ]
RHAL1_00911 pstB; phosphate transporter subunit; ATP-binding component of ABC superfamily protein [KO:K02036 ] [EC:7.3.2.1 ]
RHAL1_03717 livK; leucine transporter subunit; periplasmic-binding component of ABC superfamily protein [KO:K01999 ]
RHAL1_03718 livH; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily protein [KO:K01997 ]
RHAL1_00918 putative branched-chain amino acid permease protein (ABC superfamily, membrane) [KO:K01997 ]
RHAL1_00919 livM_1; Branched-chain amino acid transport system permease protein [KO:K01998 ]
RHAL1_03719 livM_2; leucine/isoleucine/valine transporter subunit; membrane component of ABC superfamily protein [KO:K01998 ]
RHAL1_01420 braF; High-affinity branched-chain amino acid transport ATP-binding protein BraF [KO:K01995 ]
RHAL1_00921 livF_1; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily protein [KO:K01996 ]
RHAL1_01419 livF_2; leucine/isoleucine/valine transporter subunit; ATP-binding component of ABC superfamily protein [KO:K01996 ]
RHAL1_02523 Amino acid/amide ABC transporter membrane protein 1, HAAT family [KO:K11960 ]
RHAL1_02520 braG; High-affinity branched-chain amino acid transport ATP-binding protein BraG [KO:K11963 ]
RHAL1_00110 oppB; oligopeptide transporter subunit; membrane component of ABC superfamily protein [KO:K15581 ]
RHAL1_03090 yejB; putative oligopeptide transporter subunit; permease component of ABC superfamily protein [KO:K13894 ]
RHAL1_03089 yejE; putative oligopeptide transporter subunit; permease component of ABC superfamily transporter [KO:K13895 ]
RHAL1_03088 yejF; putative fused oligopeptide transporter subunits of ABC superfamily: ATP-binding components [KO:K13896 ]
RHAL1_02017 putative Vi polysaccharide export inner membrane protein VexD [KO:K10107 ]
RHAL1_01470 lolD; outer membrane-specific lipoprotein transporter subunit; ATP-binding component of ABC superfamily protein [KO:K09810 ] [EC:7.6.2.-]
RHAL1_04009 ccmC; heme exporter subunit; membrane component of ABC superfamily protein [KO:K02195 ]
RHAL1_03418 ccmB; heme exporter subunit; membrane component of ABC superfamily protein [KO:K02194 ]
RHAL1_00990 lptB; putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily protein [KO:K06861 ] [EC:7.5.2.5 ]
RHAL1_03132 ftsE; transporter subunit: ATP-binding component of ABC superfamily protein [KO:K09812 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
