Entry
Name
ABC transporters - Bifidobacterium breve JCM 7019
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Bifidobacterium breve JCM 7019 [GN:
bbrc ]
Gene
B7019_2077 ATP-binding protein of ABC transporter system for sugars [KO:K10112 ] [EC:7.5.2.-]
B7019_2051 Solute binding protein of ABC transporter system for sugars [KO:K10117 ]
B7019_2053 Solute binding protein of ABC transporter system for sugars [KO:K10117 ]
B7019_0272 Solute-binding protein of ABC transporter system for sugars, galactan metabolism [KO:K10188 ]
B7019_0848 Solute binding protein of ABC transporter system for sugars [KO:K17318 ]
B7019_1200 putative solute binding protein of ABC transporter system [KO:K10005 ]
B7019_1928 Solute binding protein of ABC transporter system for amino acids [KO:K16957 ]
B7019_1929 Permease protein of ABC transporter system for amino acids [KO:K16958 ]
B7019_1930 Permease protein of ABC transporter system for amino acids [KO:K16959 ]
B7019_1674 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
B7019_1673 Branched-chain amino acid transport system permease protein livH [KO:K01997 ]
B7019_1672 Branched-chain amino acid transport system permease protein livM [KO:K01998 ]
B7019_1671 Branched-chain amino acid transport ATP-binding protein livG [KO:K01995 ]
B7019_1670 Branched-chain amino acid transport ATP-binding protein livF [KO:K01996 ]
B7019_0521 Solute-binding protein of ABC transporter system for peptides [KO:K15580 ]
B7019_1021 Solute binding protein of ABC transporter system for peptides [KO:K15580 ]
B7019_0637 ATP-binding protein of ABC transporter system [KO:K16784 ] [EC:7.6.2.-]
B7019_0650 Permease protein of ABC transporter system, probably involved in thiamine metabolism [KO:K16785 ]
B7019_1996 ATP-binding and permease protein of ABC multidrug transporter system [KO:K18889 ]
B7019_1995 ATP-binding and permease protein of ABC multidrug transporter system [KO:K18890 ]
B7019_2012 ATP-binding and permease protein of ABC transporter system [KO:K18887 ]
B7019_2011 ATP-binding and permease protein of ABC transporter system [KO:K18888 ]
B7019_0379 ATP-binding and permeaase modules of ABC transporter system [KO:K16014 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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