Entry Name ABC transporters - Anaerostipes hadrus
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Anaerostipes hadrus [GN:
bprl ]
Gene CL2_13450 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
CL2_15550 ABC-type spermidine/putrescine transport system, permease component II [KO:K11070 ]
CL2_15540 ABC-type spermidine/putrescine transport system, permease component I [KO:K11071 ]
CL2_21360 carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-) [KO:K10117 ]
CL2_21400 ABC-type sugar transport system, periplasmic component [KO:K10117 ]
CL2_27140 monosaccharide ABC transporter substrate-binding protein, CUT2 family (TC 3.A.1.2.-) [KO:K10439 ]
CL2_09450 monosaccharide ABC transporter substrate-binding protein, CUT2 family (TC 3.A.1.2.-) [KO:K23508 ]
CL2_09480 monosaccharide ABC transporter membrane protein, CUT2 family (TC 3.A.1.2.-) [KO:K23509 ]
CL2_09470 monosaccharide ABC transporter membrane protein, CUT2 family (TC 3.A.1.2.-) [KO:K23509 ]
CL2_09460 monosaccharide ABC transporter ATP-binding protein, CUT2 family (TC 3.A.1.2.-) [KO:K10820 ] [EC:7.5.2.9 ]
CL2_28170 phosphate ABC transporter substrate-binding protein, PhoT family (TC 3.A.1.7.1) [KO:K02040 ]
CL2_28180 phosphate ABC transporter membrane protein 1, PhoT family (TC 3.A.1.7.1) [KO:K02037 ]
CL2_28190 phosphate ABC transporter membrane protein 2, PhoT family (TC 3.A.1.7.1) [KO:K02038 ]
CL2_19070 amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-) [KO:K23059 ]
CL2_19080 amino acid ABC transporter membrane protein, PAAT family (TC 3.A.1.3.-) [KO:K17077 ]
CL2_17770 ABC-type metal ion transport system, periplasmic component/surface antigen [KO:K02073 ]
CL2_17790 ABC-type metal ion transport system, permease component [KO:K02072 ]
CL2_17780 ABC-type metal ion transport system, ATPase component [KO:K02071 ]
CL2_25340 ABC-type metal ion transport system, periplasmic component/surface adhesin [KO:K09815 ]
CL2_25360 ABC-type Mn2+/Zn2+ transport systems, permease components [KO:K09816 ]
CL2_06390 ABC-type cobalt transport system, permease component CbiQ and related transporters [KO:K16785 ]
CL2_06370 ABC-type cobalt transport system, ATPase component [KO:K16786 ] [EC:7.-.-.-]
CL2_06380 ABC-type cobalt transport system, ATPase component [KO:K16787 ] [EC:7.-.-.-]
CL2_09140 ABC-type multidrug transport system, ATPase component [KO:K11050 ]
CL2_02600 ABC-type multidrug transport system, ATPase component [KO:K16921 ]
CL2_04360 ABC-type multidrug transport system, ATPase and permease components [KO:K14698 ] [EC:7.-.-.-]
CL2_20790 ABC-type multidrug transport system, ATPase and permease components [KO:K14698 ] [EC:7.-.-.-]
CL2_04370 ABC-type multidrug transport system, ATPase and permease components [KO:K14699 ] [EC:7.-.-.-]
CL2_20800 ABC-type multidrug transport system, ATPase and permease components [KO:K14699 ] [EC:7.-.-.-]
CL2_29080 ABC-type multidrug transport system, ATPase and permease components [KO:K14699 ] [EC:7.-.-.-]
CL2_24950 ABC-type multidrug transport system, ATPase and permease components [KO:K18887 ]
CL2_09560 ABC-type multidrug transport system, ATPase and permease components [KO:K18887 ]
CL2_04830 ABC-type multidrug transport system, ATPase and permease components [KO:K18887 ]
CL2_09570 ABC-type multidrug transport system, ATPase and permease components [KO:K18888 ]
CL2_04840 ABC-type multidrug transport system, ATPase and permease components [KO:K18888 ]
CL2_24960 ABC-type multidrug transport system, ATPase and permease components [KO:K18888 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
