PATHWAY: bpsd02010 Help
Entry
Name
ABC transporters - Burkholderia pseudomallei MSHR520
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Burkholderia pseudomallei MSHR520 [GN:
bpsd ]
Gene
BBX_20 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
BBX_2305 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
BBX_2304 cysT; sulfate ABC transporter, permease protein CysT [KO:K02046 ]
BBX_2303 cysW; sulfate ABC transporter, permease protein CysW [KO:K02047 ]
BBX_4084 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
BBX_4082 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
BBX_2710 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
BBX_6057 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
BBX_299 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
BBX_2326 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBX_2287 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBX_297 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBX_4351 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
BBX_1119 bacterial extracellular solute-binding family protein [KO:K02020 ]
BBX_4352 modB; molybdate ABC transporter, permease protein [KO:K02018 ]
BBX_2685 bacterial extracellular solute-binding family protein [KO:K02012 ]
BBX_5771 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BBX_2686 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BBX_5080 bacterial extracellular solute-binding family protein [KO:K11069 ]
BBX_5079 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
BBX_5078 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
BBX_2039 bacterial extracellular solute-binding family protein [KO:K11073 ]
BBX_2042 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BBX_5529 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BBX_2041 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BBX_5530 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BBX_5414 phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081 ]
BBX_5417 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
BBX_5416 phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083 ]
BBX_5415 phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084 ]
BBX_3893 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBX_5621 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
BBX_5626 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBX_5631 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBX_2195 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
BBX_2196 putative osmoprotectant uptake system permease protein yehY [KO:K05846 ]
BBX_2199 putative osmoprotectant uptake system permease protein yehW [KO:K05846 ]
BBX_3145 bacterial extracellular solute-binding family protein [KO:K10227 ]
BBX_3144 binding--dependent transport system inner membrane component family protein [KO:K10228 ]
BBX_3143 binding--dependent transport system inner membrane component family protein [KO:K10229 ]
BBX_1237 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
BBX_1238 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
BBX_6171 ABC sugar (Ribose) transporter, periplasmic substrate-binding subunit [KO:K10439 ]
BBX_2257 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBX_5199 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBX_2300 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBX_5906 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBX_6168 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBX_6169 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBX_2255 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBX_5200 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBX_2298 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBX_869 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10537 ]
BBX_871 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
BBX_5321 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17205 ]
BBX_5320 branched-chain amino acid transport system / permease component family protein [KO:K17206 ]
BBX_624 bacterial extracellular solute-binding family protein [KO:K05813 ]
BBX_625 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
BBX_626 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
BBX_2597 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
BBX_2596 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
BBX_2595 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
BBX_994 phnD; phosphonate ABC transporter, periplasmic phosphonate binding protein [KO:K02044 ]
BBX_995 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
BBX_1508 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BBX_5334 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BBX_4662 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
BBX_387 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
BBX_1497 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBX_6118 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBX_2951 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBX_1496 hisQ; histidine transport system permease protein hisQ [KO:K10016 ]
BBX_6117 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BBX_2950 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BBX_2949 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10014 ]
BBX_4985 bacterial extracellular solute-binding s, 3 family protein [KO:K10036 ]
BBX_4984 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037 ]
BBX_913 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
BBX_915 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002 ]
BBX_914 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003 ]
BBX_2337 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BBX_1232 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BBX_2338 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BBX_1231 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BBX_352 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
BBX_382 receptor ligand binding region family protein [KO:K01999 ]
BBX_483 receptor ligand binding region family protein [KO:K01999 ]
BBX_5640 braC; leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
BBX_2475 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_286 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_353 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_357 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_3049 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_5641 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBX_2474 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BBX_358 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BBX_287 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBX_354 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBX_3048 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBX_5642 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBX_5644 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
BBX_5386 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
BBX_1335 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
BBX_1193 urtB; urea ABC transporter, permease protein UrtB [KO:K11960 ]
BBX_1192 urtC; urea ABC transporter, permease protein UrtC [KO:K11961 ]
BBX_1191 urtD; urea ABC transporter, ATP-binding protein UrtD [KO:K11962 ]
BBX_1190 urtE; urea ABC transporter, ATP-binding protein UrtE [KO:K11963 ]
BBX_4773 oppB; oligopeptide transport system permease protein oppB [KO:K15581 ]
BBX_4772 oppC; oligopeptide transport system permease protein oppC [KO:K15582 ]
BBX_4771 oligopeptide/dipeptide ABC transporter, ATP-binding , C-terminal domain protein [KO:K15583 ]
BBX_4770 oligopeptide/dipeptide ABC transporter, ATP-binding , C-terminal domain protein [KO:K10823 ]
BBX_128 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BBX_3555 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BBX_127 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
BBX_126 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
BBX_125 oligopeptide/dipeptide ABC transporter, ATP-binding , C-terminal domain protein [KO:K12371 ]
BBX_124 oligopeptide/dipeptide ABC transporter, ATP-binding , C-terminal domain protein [KO:K12372 ]
BBX_3769 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889 ]
BBX_3768 gsiC; glutathione transport system permease protein gsiC [KO:K13890 ]
BBX_3767 gsiD; glutathione transport system permease protein gsiD [KO:K13891 ]
BBX_1741 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
BBX_1742 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
BBX_1743 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
BBX_1613 liporeleasing system, transmembrane , LolC/E family protein [KO:K09808 ]
BBX_1614 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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