PATHWAY: bpsh02010 Help
Entry
Name
ABC transporters - Burkholderia pseudomallei HBPUB10134a
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Burkholderia pseudomallei HBPUB10134a [GN:
bpsh ]
Gene
DR55_2941 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
DR55_3701 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
DR55_3703 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
DR55_3350 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR55_4408 ABC transporter, substrate-binding , aliphatic sulfonates family protein [KO:K15553 ]
DR55_1037 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
DR55_2961 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR55_2923 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR55_1035 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
DR55_3476 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
DR55_1793 bacterial extracellular solute-binding family protein [KO:K02020 ]
DR55_4646 bacterial extracellular solute-binding family protein [KO:K02012 ]
DR55_3325 bacterial extracellular solute-binding family protein [KO:K02012 ]
DR55_4647 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DR55_3326 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
DR55_946 bacterial extracellular solute-binding family protein [KO:K11069 ]
DR55_5291 bacterial extracellular solute-binding family protein [KO:K11069 ]
DR55_945 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
DR55_5292 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
DR55_944 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
DR55_5293 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
DR55_2670 bacterial extracellular solute-binding family protein [KO:K11073 ]
DR55_4883 bacterial extracellular solute-binding family protein [KO:K11073 ]
DR55_2673 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DR55_4886 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
DR55_2672 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
DR55_4885 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
DR55_5003 phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081 ]
DR55_5000 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
DR55_5001 phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083 ]
DR55_5002 phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084 ]
DR55_3852 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR55_4785 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR55_4790 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
DR55_4795 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
DR55_2829 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
DR55_2830 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DR55_2833 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
DR55_291 bacterial extracellular solute-binding family protein [KO:K10227 ]
DR55_290 binding--dependent transport system inner membrane component family protein [KO:K10228 ]
DR55_289 binding--dependent transport system inner membrane component family protein [KO:K10229 ]
DR55_1910 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
DR55_1911 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
DR55_4300 ABC sugar (Ribose) transporter, periplasmic substrate-binding subunit [KO:K10439 ]
DR55_2892 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR55_5224 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR55_2936 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR55_4555 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
DR55_4302 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR55_2890 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR55_5223 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR55_4303 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR55_2934 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
DR55_1548 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10537 ]
DR55_1550 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
DR55_5100 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17205 ]
DR55_5101 branched-chain amino acid transport system / permease component family protein [KO:K17206 ]
DR55_1336 bacterial extracellular solute-binding family protein [KO:K05813 ]
DR55_1337 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
DR55_1338 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
DR55_3238 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
DR55_3237 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
DR55_3236 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
DR55_1669 phnD; phosphonate ABC transporter, periplasmic phosphonate binding protein [KO:K02044 ]
DR55_1670 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
DR55_5087 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
DR55_1123 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
DR55_2138 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
DR55_103 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
DR55_4350 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
DR55_2128 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
DR55_102 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
DR55_4351 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
DR55_2127 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
DR55_101 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10014 ]
DR55_5388 bacterial extracellular solute-binding s, 3 family protein [KO:K10036 ]
DR55_5389 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037 ]
DR55_1592 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
DR55_1594 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002 ]
DR55_1593 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003 ]
DR55_1905 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DR55_2972 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
DR55_1904 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DR55_2973 amino ABC transporter, permease , 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
DR55_1089 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
DR55_4776 braC; leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
DR55_1090 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_1094 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_1023 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_3111 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_4775 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_196 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
DR55_1095 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DR55_3110 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
DR55_4774 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR55_1024 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR55_195 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR55_1091 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
DR55_4772 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
DR55_5031 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DR55_2008 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
DR55_5586 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K15580 ]
DR55_5587 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
DR55_5588 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
DR55_709 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DR55_840 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
DR55_839 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
DR55_838 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
DR55_3975 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889 ]
DR55_3976 binding--dependent transport system inner membrane component family protein [KO:K13890 ]
DR55_3977 gsiD; glutathione transport system permease protein gsiD [KO:K13891 ]
DR55_2376 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
DR55_2377 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
DR55_2378 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
DR55_2244 liporeleasing system, transmembrane , LolC/E family protein [KO:K09808 ]
DR55_2245 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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