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Entry
Name
ABC transporters - Burkholderia pseudomallei MSHR511
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Burkholderia pseudomallei MSHR511 [GN:
bpsm ]
Gene
BBQ_3057 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
BBQ_1703 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
BBQ_1702 cysT; sulfate ABC transporter, permease protein CysT [KO:K02046 ]
BBQ_1701 cysW; sulfate ABC transporter, permease protein CysW [KO:K02047 ]
BBQ_4574 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
BBQ_4576 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
BBQ_5209 ABC transporter, substrate-binding, aliphatic sulfonates family protein [KO:K15553 ]
BBQ_2199 ABC transporter, substrate-binding, aliphatic sulfonates family protein [KO:K15553 ]
BBQ_3368 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
BBQ_1723 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBQ_1685 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBQ_3366 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BBQ_4348 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
BBQ_586 bacterial extracellular solute-binding family protein [KO:K02020 ]
BBQ_4347 modB; molybdate ABC transporter, permease protein [KO:K02018 ]
BBQ_5489 bacterial extracellular solute-binding family protein [KO:K02012 ]
BBQ_2174 bacterial extracellular solute-binding family protein [KO:K02012 ]
BBQ_5490 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BBQ_2175 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BBQ_3667 bacterial extracellular solute-binding family protein [KO:K11069 ]
BBQ_3668 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
BBQ_3669 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
BBQ_5727 bacterial extracellular solute-binding family protein [KO:K11073 ]
BBQ_1426 bacterial extracellular solute-binding family protein [KO:K11073 ]
BBQ_5730 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BBQ_1429 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BBQ_5729 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BBQ_1428 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BBQ_5855 phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081 ]
BBQ_5852 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
BBQ_5853 phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083 ]
BBQ_5854 phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084 ]
BBQ_4725 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBQ_5628 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBQ_5633 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BBQ_5638 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
BBQ_1596 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
BBQ_1597 putative osmoprotectant uptake system permease protein yehY [KO:K05846 ]
BBQ_1600 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
BBQ_2619 bacterial extracellular solute-binding family protein [KO:K10227 ]
BBQ_2618 binding--dependent transport system inner membrane component family protein [KO:K10228 ]
BBQ_2617 binding--dependent transport system inner membrane component family protein [KO:K10229 ]
BBQ_704 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
BBQ_705 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
BBQ_5098 ABC sugar (Ribose) transporter, periplasmic substrate-binding subunit [KO:K10439 ]
BBQ_1654 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBQ_1698 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBQ_3547 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBQ_5356 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10439 ]
BBQ_5100 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBQ_1652 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBQ_1696 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBQ_3546 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BBQ_5099 branched-chain amino acid transport system / permease component family protein [KO:K10441 ] [EC:7.5.2.7 ]
BBQ_337 periplasmic binding s and sugar binding domain of LacI family protein [KO:K10537 ]
BBQ_339 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
BBQ_5952 periplasmic binding s and sugar binding domain of LacI family protein [KO:K17205 ]
BBQ_5953 branched-chain amino acid transport system / permease component family protein [KO:K17206 ]
BBQ_128 bacterial extracellular solute-binding family protein [KO:K05813 ]
BBQ_129 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
BBQ_130 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
BBQ_2083 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
BBQ_2082 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
BBQ_2081 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
BBQ_461 phnD; phosphonate ABC transporter, periplasmic phosphonate binding protein [KO:K02044 ]
BBQ_462 phnE; phosphonate ABC transporter, permease protein PhnE [KO:K02042 ]
BBQ_5939 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BBQ_3455 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
BBQ_929 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BBQ_5151 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBQ_2417 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBQ_918 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BBQ_5152 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BBQ_2416 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BBQ_917 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BBQ_2415 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10014 ]
BBQ_3762 bacterial extracellular solute-binding s, 3 family protein [KO:K10036 ]
BBQ_3763 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037 ]
BBQ_381 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
BBQ_383 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002 ]
BBQ_382 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003 ]
BBQ_699 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BBQ_1734 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BBQ_698 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BBQ_1735 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BBQ_10 receptor ligand binding region family protein [KO:K01999 ]
BBQ_5619 braC; leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
BBQ_906 receptor ligand binding region family protein [KO:K01999 ]
BBQ_3421 branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein [KO:K01999 ]
BBQ_5618 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_3355 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_2524 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_3422 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_3426 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_1871 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BBQ_3427 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BBQ_5617 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBQ_3356 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBQ_2523 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBQ_3423 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BBQ_1870 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BBQ_5615 livF; high-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996 ]
BBQ_5883 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
BBQ_801 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
BBQ_661 urtB; urea ABC transporter, permease protein UrtB [KO:K11960 ]
BBQ_660 urtC; urea ABC transporter, permease protein UrtC [KO:K11961 ]
BBQ_659 urtD; urea ABC transporter, ATP-binding protein UrtD [KO:K11962 ]
BBQ_658 urtE; urea ABC transporter, ATP-binding protein UrtE [KO:K11963 ]
BBQ_3970 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
BBQ_3971 oppC; oligopeptide transport system permease protein oppC [KO:K15582 ]
BBQ_3972 oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein [KO:K15583 ]
BBQ_3973 oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein [KO:K10823 ]
BBQ_3033 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BBQ_3180 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BBQ_3179 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
BBQ_3178 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
BBQ_3177 oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein [KO:K12371 ]
BBQ_3176 oligopeptide/dipeptide ABC transporter, ATP-binding, C-terminal domain protein [KO:K12372 ]
BBQ_4849 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889 ]
BBQ_4850 gsiC; glutathione transport system permease protein gsiC [KO:K13890 ]
BBQ_4851 gsiD; glutathione transport system permease protein gsiD [KO:K13891 ]
BBQ_1128 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
BBQ_1129 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
BBQ_1130 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
BBQ_1036 liporeleasing system, transmembrane, LolC/E family protein [KO:K09808 ]
BBQ_1037 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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