KEGG   PATHWAY: bthl02010
Entry
bthl02010                   Pathway                                
Name
ABC transporters - Burkholderia thailandensis 2002721643
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
bthl02010  ABC transporters
bthl02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Burkholderia thailandensis 2002721643 [GN:bthl]
Gene
BG87_218  sulfate ABC transporter, sulfate-binding family protein [KO:K02048]
BG87_2378  sulfate ABC transporter, sulfate-binding family protein [KO:K23163]
BG87_2377  cysT; sulfate ABC transporter, permease protein CysT [KO:K02046]
BG87_2376  cysW; sulfate ABC transporter, permease protein CysW [KO:K02047]
BG87_2375  cysA; sulfate ABC transporter, ATP-binding family protein [KO:K02045] [EC:7.3.2.3]
BG87_3542  tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551]
BG87_3544  binding--dependent transport system inner membrane component family protein [KO:K15552]
BG87_3543  ABC transporter family protein [KO:K10831] [EC:7.6.2.7]
BG87_4213  ABC transporter, substrate-binding, aliphatic sulfonates family protein [KO:K15553]
BG87_508  bacterial extracellular solute-binding s, 3 family protein [KO:K15553]
BG87_2397  binding--dependent transport system inner membrane component family protein [KO:K15554]
BG87_506  binding--dependent transport system inner membrane component family protein [KO:K15554]
BG87_2396  ABC transporter family protein [KO:K15555] [EC:7.6.2.14]
BG87_507  ABC transporter family protein [KO:K15555] [EC:7.6.2.14]
BG87_5720  modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020]
BG87_1300  bacterial extracellular solute-binding family protein [KO:K02020]
BG87_5719  modB; molybdate ABC transporter, permease protein [KO:K02018]
BG87_5718  ABC transporter family protein [KO:K02017] [EC:7.3.2.5]
BG87_2756  bacterial extracellular solute-binding family protein [KO:K02012]
BG87_4469  bacterial extracellular solute-binding family protein [KO:K02012]
BG87_2757  binding--dependent transport system inner membrane component family protein [KO:K02011]
BG87_4470  binding--dependent transport system inner membrane component family protein [KO:K02011]
BG87_2758  ABC transporter family protein [KO:K02010] [EC:7.2.2.7]
BG87_4471  ABC transporter family protein [KO:K02010] [EC:7.2.2.7]
BG87_5207  bacterial extracellular solute-binding family protein [KO:K11069]
BG87_5206  binding--dependent transport system inner membrane component family protein [KO:K11070]
BG87_5205  binding--dependent transport system inner membrane component family protein [KO:K11071]
BG87_2176  bacterial extracellular solute-binding family protein [KO:K11073]
BG87_4688  bacterial extracellular solute-binding family protein [KO:K11073]
BG87_2179  binding--dependent transport system inner membrane component family protein [KO:K11074]
BG87_4691  binding--dependent transport system inner membrane component family protein [KO:K11074]
BG87_2178  binding--dependent transport system inner membrane component family protein [KO:K11075]
BG87_4690  binding--dependent transport system inner membrane component family protein [KO:K11075]
BG87_2177  polyamine ABC transporter, ATP-binding family protein [KO:K11076] [EC:7.6.2.16]
BG87_4689  polyamine ABC transporter, ATP-binding family protein [KO:K11076] [EC:7.6.2.16]
BG87_4791  phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081]
BG87_4788  phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082]
BG87_4789  phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083]
BG87_4790  phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084]
BG87_3720  choX; choline ABC transporter, periplasmic binding family protein [KO:K02002]
BG87_4590  choX; choline ABC transporter, periplasmic binding family protein [KO:K02002]
BG87_4595  choX; choline ABC transporter, periplasmic binding family protein [KO:K02002]
BG87_4600  substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002]
BG87_3898  substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002]
BG87_3718  choW; choline ABC transporter, permease protein [KO:K02001]
BG87_3717  proV; glycine betaine/L-proline transport ATP binding subunit [KO:K02000] [EC:7.6.2.9]
BG87_2278  substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845]
BG87_2279  binding--dependent transport system inner membrane component family protein [KO:K05846]
BG87_2281  binding--dependent transport system inner membrane component family protein [KO:K05846]
BG87_2280  ABC transporter family protein [KO:K05847] [EC:7.6.2.9]
BG87_3197  ABC transporter family protein [KO:K10111] [EC:7.5.2.-]
BG87_3915  ABC transporter family protein [KO:K10112] [EC:7.5.2.-]
BG87_1454  ABC transporter family protein [KO:K10112] [EC:7.5.2.-]
BG87_3201  bacterial extracellular solute-binding family protein [KO:K10227]
BG87_3200  binding--dependent transport system inner membrane component family protein [KO:K10228]
BG87_3199  binding--dependent transport system inner membrane component family protein [KO:K10229]
BG87_886  toluene tolerance, Ttg2 family protein [KO:K07323]
BG87_5079  toluene tolerance, Ttg2 family protein [KO:K07323]
BG87_167  mce related family protein [KO:K02067]
BG87_884  mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067]
BG87_169  ABC transport permease subunit [KO:K02066]
BG87_883  ABC transport permease subunit [KO:K02066]
BG87_887  STAS domain protein [KO:K07122]
BG87_168  ABC transporter family protein [KO:K02065]
BG87_882  ABC transporter family protein [KO:K02065]
BG87_1451  bacterial extracellular solute-binding family protein [KO:K17315]
BG87_1452  binding--dependent transport system inner membrane component family protein [KO:K17316]
BG87_1453  binding--dependent transport system inner membrane component family protein [KO:K17317]
BG87_2335  periplasmic binding domain protein [KO:K10439]
BG87_2373  periplasmic binding domain protein [KO:K10439]
BG87_5332  periplasmic binding domain protein [KO:K10439]
BG87_4353  periplasmic binding domain protein [KO:K10439]
BG87_2333  branched-chain amino acid transport system / permease component family protein [KO:K10440]
BG87_2371  branched-chain amino acid transport system / permease component family protein [KO:K10440]
BG87_5333  branched-chain amino acid transport system / permease component family protein [KO:K10440]
BG87_5334  ABC transporter family protein [KO:K10441] [EC:7.5.2.7]
BG87_2334  ABC transporter family protein [KO:K10441] [EC:7.5.2.7]
BG87_2372  ccmA; heme ABC exporter, ATP-binding protein CcmA [KO:K10441] [EC:7.5.2.7]
BG87_1071  periplasmic binding domain protein [KO:K10537]
BG87_4373  periplasmic binding domain protein [KO:K10537]
BG87_1073  branched-chain amino acid transport system / permease component family protein [KO:K10538]
BG87_4371  branched-chain amino acid transport system / permease component family protein [KO:K10538]
BG87_1072  ABC transporter family protein [KO:K10539] [EC:7.5.2.12]
BG87_4372  ccmA; heme ABC exporter, ATP-binding protein CcmA [KO:K10539] [EC:7.5.2.12]
BG87_2244  periplasmic binding domain protein [KO:K23508]
BG87_2247  branched-chain amino acid transport system / permease component family protein [KO:K23509]
BG87_2246  branched-chain amino acid transport system / permease component family protein [KO:K23509]
BG87_2245  ccmA; heme ABC exporter, ATP-binding protein CcmA [KO:K10820] [EC:7.5.2.9]
BG87_2241  xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543]
BG87_2243  branched-chain amino acid transport system / permease component family protein [KO:K10544]
BG87_2242  xylG; D-xylose ABC transporter, ATP-binding protein [KO:K10545] [EC:7.5.2.10]
BG87_866  bacterial extracellular solute-binding family protein [KO:K05813]
BG87_867  binding--dependent transport system inner membrane component family protein [KO:K05814]
BG87_868  binding--dependent transport system inner membrane component family protein [KO:K05815]
BG87_869  ABC transporter family protein [KO:K05816] [EC:7.6.2.10]
BG87_2670  pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040]
BG87_2669  pstC; phosphate ABC transporter, permease protein PstC [KO:K02037]
BG87_2668  pstA; phosphate ABC transporter, permease protein PstA [KO:K02038]
BG87_2667  pstB; phosphate ABC transporter, ATP-binding protein [KO:K02036] [EC:7.3.2.1]
BG87_4872  lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013]
BG87_1687  lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013]
BG87_592  bacterial extracellular solute-binding s, 3 family protein [KO:K10013]
BG87_1676  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015]
BG87_4153  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015]
BG87_3010  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015]
BG87_1675  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016]
BG87_4154  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016]
BG87_3009  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016]
BG87_1677  ABC transporter family protein [KO:K10017] [EC:7.4.2.1]
BG87_4152  ABC transporter family protein [KO:K10017] [EC:7.4.2.1]
BG87_3011  ABC transporter family protein [KO:K10017] [EC:7.4.2.1]
BG87_3008  lysine-arginine-ornithine-binding periplasmic family protein [KO:K10014]
BG87_5100  bacterial extracellular solute-binding s, 3 family protein [KO:K10036]
BG87_5099  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037]
BG87_5098  ABC transporter family protein [KO:K10038] [EC:7.4.2.1]
BG87_1115  bacterial extracellular solute-binding s, 3 family protein [KO:K10001]
BG87_4400  gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001]
BG87_1117  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002]
BG87_1116  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003]
BG87_1118  ABC transporter family protein [KO:K10004] [EC:7.4.2.1]
BG87_2408  bacterial extracellular solute-binding s, 3 family protein [KO:K02424]
BG87_1446  bacterial extracellular solute-binding s, 3 family protein [KO:K02424]
BG87_2409  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009]
BG87_1445  amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009]
BG87_1444  ABC transporter family protein [KO:K10010] [EC:7.4.2.1]
BG87_2838  periplasmic binding domain protein [KO:K01999]
BG87_725  receptor ligand binding region family protein [KO:K01999]
BG87_4580  braC; leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999]
BG87_4292  receptor ligand binding region family protein [KO:K01999]
BG87_1665  receptor ligand binding region family protein [KO:K01999]
BG87_4341  receptor ligand binding region family protein [KO:K01999]
BG87_494  periplasmic binding domain protein [KO:K01999]
BG87_559  periplasmic binding domain protein [KO:K01999]
BG87_563  receptor ligand binding region family protein [KO:K01999]
BG87_587  receptor ligand binding region family protein [KO:K01999]
BG87_562  hypothetical protein [KO:K01999]
BG87_4579  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_495  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_2546  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_560  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_564  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_3110  branched-chain amino acid transport system / permease component family protein [KO:K01997]
BG87_565  branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998]
BG87_4578  branched-chain amino acid transport system / permease component family protein [KO:K01998]
BG87_496  branched-chain amino acid transport system / permease component family protein [KO:K01998]
BG87_561  branched-chain amino acid transport system / permease component family protein [KO:K01998]
BG87_3109  branched-chain amino acid transport system / permease component family protein [KO:K01998]
BG87_2545  branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998]
BG87_4577  ABC transporter family protein [KO:K01995]
BG87_497  ABC transporter family protein [KO:K01995]
BG87_557  ABC transporter family protein [KO:K01995]
BG87_3108  ABC transporter family protein [KO:K01995]
BG87_4576  ABC transporter family protein [KO:K01996]
BG87_498  ABC transporter family protein [KO:K01996]
BG87_558  ABC transporter family protein [KO:K01996]
BG87_566  ABC transporter family protein [KO:K01996]
BG87_3107  ABC transporter family protein [KO:K01996]
BG87_2544  ABC transporter family protein [KO:K01996]
BG87_4875  lipo, YaeC family protein [KO:K02073]
BG87_1551  lipo, YaeC family protein [KO:K02073]
BG87_104  lipo, YaeC family protein [KO:K02073]
BG87_4823  NLPA lipofamily protein [KO:K02073]
BG87_1550  binding--dependent transport system inner membrane component family protein [KO:K02072]
BG87_1549  ABC transporter family protein [KO:K02071]
BG87_1400  periplasmic binding domain protein [KO:K11959]
BG87_1399  urtB; urea ABC transporter, permease protein UrtB [KO:K11960]
BG87_1398  urtC; urea ABC transporter, permease protein UrtC [KO:K11961]
BG87_1397  urtD; urea ABC transporter, ATP-binding protein UrtD [KO:K11962]
BG87_1396  urtE; urea ABC transporter, ATP-binding protein UrtE [KO:K11963]
BG87_4960  oppA3; periplasmic oligopeptide-binding protein [KO:K15580]
BG87_4959  binding--dependent transport system inner membrane component family protein [KO:K15581]
BG87_4958  binding--dependent transport system inner membrane component family protein [KO:K15582]
BG87_4957  hypothetical protein [KO:K15583]
BG87_4956  hypothetical protein [KO:K10823]
BG87_320  bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368]
BG87_193  bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368]
BG87_319  binding--dependent transport system inner membrane component family protein [KO:K12369]
BG87_318  binding--dependent transport system inner membrane component family protein [KO:K12370]
BG87_317  hypothetical protein [KO:K12371]
BG87_316  hypothetical protein [KO:K12372]
BG87_3857  bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889]
BG87_3858  binding--dependent transport system inner membrane component family protein [KO:K13890]
BG87_3859  binding--dependent transport system inner membrane component family protein [KO:K13891]
BG87_3856  nikE; nickel import ATP-binding protein NikE [KO:K13892]
BG87_1887  bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893]
BG87_1888  binding--dependent transport system inner membrane component family protein [KO:K13894]
BG87_1889  binding--dependent transport system inner membrane component family protein [KO:K13895]
BG87_1890  nikE; nickel import ATP-binding protein NikE [KO:K13896]
BG87_2322  periplasmic binding family protein [KO:K23227]
BG87_2324  fecCD transport family protein [KO:K23228]
BG87_2325  ABC transporter family protein [KO:K10829] [EC:7.2.2.16]
BG87_1225  chain length determinant family protein [KO:K10107]
BG87_1224  ABC-2 type transporter family protein [KO:K09688]
BG87_1223  ABC transporter family protein [KO:K09689] [EC:7.6.2.12]
BG87_1372  ABC-2 type transporter family protein [KO:K09690]
BG87_1373  ABC transporter family protein [KO:K09691] [EC:7.5.2.14]
BG87_2384  ABC-2 type transporter, NodJ family protein [KO:K09694]
BG87_2383  nodI; nodulation ABC transporter NodI [KO:K09695]
BG87_1792  liporeleasing system, transmembrane, LolC/E family protein [KO:K09808]
BG87_1793  lolD; liporeleasing system, ATP-binding protein [KO:K09810] [EC:7.6.2.-]
BG87_3075  lptF; LPS export ABC transporter permease LptF [KO:K07091]
BG87_3076  lptG; LPS export ABC transporter permease LptG [KO:K11720]
BG87_56  lptB; LPS export ABC transporter ATP-binding protein [KO:K06861] [EC:7.5.2.5]
BG87_2223  ABC-2 transporter family protein [KO:K19341]
BG87_2224  ABC transporter family protein [KO:K19340]
BG87_2909  msbA; lipid A export permease/ATP-binding protein MsbA [KO:K11085] [EC:7.5.2.6]
BG87_934  ABC transporter family protein [KO:K13409]
BG87_3879  ABC transporter family protein [KO:K13409]
BG87_3321  ABC transporter family protein [KO:K24821]
BG87_4535  ABC transporter family protein [KO:K05685] [EC:7.6.2.-]
BG87_2320  cyclic peptide transporter family protein [KO:K06160]
BG87_877  ABC transporter family protein [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
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