PATHWAY: bthl02010 Help
Entry
Name
ABC transporters - Burkholderia thailandensis 2002721643
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Burkholderia thailandensis 2002721643 [GN:
bthl ]
Gene
BG87_218 sulfate ABC transporter, sulfate-binding family protein [KO:K02048 ]
BG87_2378 sulfate ABC transporter, sulfate-binding family protein [KO:K23163 ]
BG87_3542 tauA; taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
BG87_3544 binding--dependent transport system inner membrane component family protein [KO:K15552 ]
BG87_4213 ABC transporter, substrate-binding, aliphatic sulfonates family protein [KO:K15553 ]
BG87_508 bacterial extracellular solute-binding s, 3 family protein [KO:K15553 ]
BG87_2397 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BG87_506 binding--dependent transport system inner membrane component family protein [KO:K15554 ]
BG87_5720 modA; molybdate ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
BG87_1300 bacterial extracellular solute-binding family protein [KO:K02020 ]
BG87_2756 bacterial extracellular solute-binding family protein [KO:K02012 ]
BG87_4469 bacterial extracellular solute-binding family protein [KO:K02012 ]
BG87_2757 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BG87_4470 binding--dependent transport system inner membrane component family protein [KO:K02011 ]
BG87_5207 bacterial extracellular solute-binding family protein [KO:K11069 ]
BG87_5206 binding--dependent transport system inner membrane component family protein [KO:K11070 ]
BG87_5205 binding--dependent transport system inner membrane component family protein [KO:K11071 ]
BG87_2176 bacterial extracellular solute-binding family protein [KO:K11073 ]
BG87_4688 bacterial extracellular solute-binding family protein [KO:K11073 ]
BG87_2179 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BG87_4691 binding--dependent transport system inner membrane component family protein [KO:K11074 ]
BG87_2178 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BG87_4690 binding--dependent transport system inner membrane component family protein [KO:K11075 ]
BG87_4791 phnS; 2-aminoethylphosphonate ABC transporter, 2-aminoethylphosphonate binding protein [KO:K11081 ]
BG87_4788 phnV; 2-aminoethylphosphonate ABC transport system, membrane component PhnV [KO:K11082 ]
BG87_4789 phnU; 2-aminoethylphosphonate ABC transporter, permease protein [KO:K11083 ]
BG87_4790 phnT; 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT [KO:K11084 ]
BG87_3720 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BG87_4590 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BG87_4595 choX; choline ABC transporter, periplasmic binding family protein [KO:K02002 ]
BG87_4600 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
BG87_3898 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K02002 ]
BG87_2278 substrate binding domain of ABC-type glycine betaine transport system family protein [KO:K05845 ]
BG87_2279 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
BG87_2281 binding--dependent transport system inner membrane component family protein [KO:K05846 ]
BG87_3201 bacterial extracellular solute-binding family protein [KO:K10227 ]
BG87_3200 binding--dependent transport system inner membrane component family protein [KO:K10228 ]
BG87_3199 binding--dependent transport system inner membrane component family protein [KO:K10229 ]
BG87_884 mlaD; outer membrane lipid asymmetry maintenance protein MlaD [KO:K02067 ]
BG87_1451 bacterial extracellular solute-binding family protein [KO:K17315 ]
BG87_1452 binding--dependent transport system inner membrane component family protein [KO:K17316 ]
BG87_1453 binding--dependent transport system inner membrane component family protein [KO:K17317 ]
BG87_2333 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BG87_2371 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BG87_5333 branched-chain amino acid transport system / permease component family protein [KO:K10440 ]
BG87_1073 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
BG87_4371 branched-chain amino acid transport system / permease component family protein [KO:K10538 ]
BG87_2247 branched-chain amino acid transport system / permease component family protein [KO:K23509 ]
BG87_2246 branched-chain amino acid transport system / permease component family protein [KO:K23509 ]
BG87_2241 xylF; D-xylose ABC transporter, D-xylose-binding protein [KO:K10543 ]
BG87_2243 branched-chain amino acid transport system / permease component family protein [KO:K10544 ]
BG87_866 bacterial extracellular solute-binding family protein [KO:K05813 ]
BG87_867 binding--dependent transport system inner membrane component family protein [KO:K05814 ]
BG87_868 binding--dependent transport system inner membrane component family protein [KO:K05815 ]
BG87_2670 pstS; phosphate ABC transporter, phosphate-binding protein PstS [KO:K02040 ]
BG87_2669 pstC; phosphate ABC transporter, permease protein PstC [KO:K02037 ]
BG87_2668 pstA; phosphate ABC transporter, permease protein PstA [KO:K02038 ]
BG87_4872 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BG87_1687 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10013 ]
BG87_592 bacterial extracellular solute-binding s, 3 family protein [KO:K10013 ]
BG87_1676 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BG87_4153 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BG87_3010 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10015 ]
BG87_1675 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BG87_4154 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BG87_3009 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10016 ]
BG87_3008 lysine-arginine-ornithine-binding periplasmic family protein [KO:K10014 ]
BG87_5100 bacterial extracellular solute-binding s, 3 family protein [KO:K10036 ]
BG87_5099 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10037 ]
BG87_1115 bacterial extracellular solute-binding s, 3 family protein [KO:K10001 ]
BG87_4400 gltI; glutamate/aspartate periplasmic-binding protein [KO:K10001 ]
BG87_1117 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10002 ]
BG87_1116 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10003 ]
BG87_2408 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BG87_1446 bacterial extracellular solute-binding s, 3 family protein [KO:K02424 ]
BG87_2409 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BG87_1445 amino ABC transporter, permease, 3-TM region, His/Glu/Gln/Arg/opine family domain protein [KO:K10009 ]
BG87_4580 braC; leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein [KO:K01999 ]
BG87_4579 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_495 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_2546 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_560 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_564 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_3110 branched-chain amino acid transport system / permease component family protein [KO:K01997 ]
BG87_565 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BG87_4578 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BG87_496 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BG87_561 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BG87_3109 branched-chain amino acid transport system / permease component family protein [KO:K01998 ]
BG87_2545 branched-chain amino acid transport system / permease component family protein [KO:K01995 K01998 ]
BG87_1550 binding--dependent transport system inner membrane component family protein [KO:K02072 ]
BG87_4959 binding--dependent transport system inner membrane component family protein [KO:K15581 ]
BG87_4958 binding--dependent transport system inner membrane component family protein [KO:K15582 ]
BG87_320 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BG87_193 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K12368 ]
BG87_319 binding--dependent transport system inner membrane component family protein [KO:K12369 ]
BG87_318 binding--dependent transport system inner membrane component family protein [KO:K12370 ]
BG87_3857 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13889 ]
BG87_3858 binding--dependent transport system inner membrane component family protein [KO:K13890 ]
BG87_3859 binding--dependent transport system inner membrane component family protein [KO:K13891 ]
BG87_1887 bacterial extracellular solute-binding s, 5 Middle family protein [KO:K13893 ]
BG87_1888 binding--dependent transport system inner membrane component family protein [KO:K13894 ]
BG87_1889 binding--dependent transport system inner membrane component family protein [KO:K13895 ]
BG87_1792 liporeleasing system, transmembrane, LolC/E family protein [KO:K09808 ]
BG87_1793 lolD; liporeleasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
KO pathway
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