KEGG   PATHWAY: camh00740
Entry
camh00740                   Pathway                                
Name
Riboflavin metabolism - Cobetia amphilecti
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
camh00740  Riboflavin metabolism
camh00740

Module
camh_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:camh00740]
Other DBs
GO: 0006771
Organism
Cobetia amphilecti [GN:camh]
Gene
LCW13_00265  ribA; GTP cyclohydrolase II [KO:K01497] [EC:3.5.4.25]
LCW13_12915  bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II [KO:K14652] [EC:4.1.99.12 3.5.4.25]
LCW13_12920  ribD; bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD [KO:K11752] [EC:3.5.4.26 1.1.1.193]
LCW13_00635  HAD family hydrolase [KO:K20862] [EC:3.1.3.102 3.1.3.104]
LCW13_12910  ribE; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
LCW13_11985  riboflavin synthase subunit alpha [KO:K00793] [EC:2.5.1.9]
LCW13_16300  ribF; bifunctional riboflavin kinase/FAD synthetase [KO:K11753] [EC:2.7.1.26 2.7.7.2]
LCW13_11380  thiM; hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
LCW13_05305  NUDIX domain-containing protein [KO:K01515] [EC:3.6.1.13 3.6.1.-]
LCW13_04210  UbiX family flavin prenyltransferase [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
camh00030  Pentose phosphate pathway
camh00040  Pentose and glucuronate interconversions
camh00230  Purine metabolism
camh00860  Porphyrin metabolism
camh00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

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