PATHWAY: camp02010 Help
Entry
Name
ABC transporters - Campylobacter fetus subsp. testudinum 03-427
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
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Organism
Campylobacter fetus subsp. testudinum 03-427 [GN:
camp ]
Gene
CFT03427_0371 modA; molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
CFT03427_0122 putative ABC-type iron(III) transporter, periplasmic iron-binding protein [KO:K02012 ]
CFT03427_0190 pstS; phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040 ]
CFT03427_1142 amino acid ABC transporter, periplasmic amino acid-binding protein PEB1 [KO:K10039 ]
CFT03427_0408 livK; high-affinity branched-chain amino acid transporter, periplasmic Leu/Ile/Val-binding protein [KO:K01999 ]
CFT03427_0409 livH; high-affinity branched-chain amino acid transporter, permease protein [KO:K01997 ]
CFT03427_0410 livM; high-affinity branched-chain amino acid transporter, permease protein [KO:K01998 ]
CFT03427_0411 livG; high-affinity branched-chain amino acid transporter, ATP-binding protein [KO:K01995 ]
CFT03427_0412 livF; high-affinity branched-chain amino acid transporter, ATP-binding protein [KO:K01996 ]
CFT03427_0712 putative Mn2+/Fe2+ ABC transporter, periplasmic substrate-binding protein [KO:K11604 ]
CFT03427_0181 cbiM; putative ABC-type Co/Ni periplasmic permease CbiKLMQO, membrane protein CbiM [KO:K02007 ]
CFT03427_0183 cbiQ; putative ABC-type Co/Ni periplasmic permease CbiKLMQO, membrane protein CbiQ [KO:K02008 ]
CFT03427_0184 cbiO; putative ABC-type Co/Ni periplasmic permease CbiKLMQO, ATP-binding protein CbiO [KO:K02006 ]
CFT03427_0180 cbiK; putative ABC-type Co/Ni periplasmic permease CbiKLMQO, periplasmic binding protein CbiK [KO:K10094 ]
CFT03427_0182 cbiL; putative ABC-type Co/Ni periplasmic permease CbiKLMQO, membrane protein CbiL [KO:K16915 ]
CFT03427_0737 YjgP/YjgQ family permease, possible lipopolysaccharide transport protein [KO:K07091 ]
CFT03427_0279 YjgP/YjgQ family permease, possible lipopolysaccharide transport protein [KO:K11720 ]
CFT03427_0749 macB; macrolide-specific efflux protein, ATP-binding/permease protein MacB [KO:K05685 ] [EC:7.6.2.-]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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