Entry
Name
ABC transporters - Clostridium botulinum H04402 065
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Clostridium botulinum H04402 065 [GN:
cbj ]
Gene
H04402_01553 molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1) [KO:K02020 ]
H04402_00596 ABC transporter, periplasmic spermidine putrescine-binding protein PotD (TC 3.A.1.11.1) / Spermidine Putrescine ABC transporter permease component potC (TC_3.A.1.11.1) [KO:K11069 K11070 ]
H04402_00595 spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) [KO:K11071 ]
H04402_01709 L-proline glycine betaine binding ABC transporter protein proX (TC 3.A.1.12.1) / Osmotic adaptation [KO:K05845 K05846 ]
H04402_01581 sn-glycerol-3-phosphate transport ATP-binding protein UgpC (TC 3.A.1.1.3) [KO:K10112 ] [EC:7.5.2.-]
H04402_00211 unspecified monosaccharide ABC transport system,permease component 2 [KO:K23536 ]
H04402_00399 phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) [KO:K02040 ]
H04402_02557 phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) [KO:K02040 ]
H04402_01250 amino acid ABC transporter, periplasmic amino acid-binding portion [KO:K16961 ]
H04402_01470 cystine ABC transporter, periplasmic cystine-binding protein FliY [KO:K16961 ]
H04402_00473 branched-chain amino acid ABC transporter, amino acid-binding protein (TC 3.A.1.4.1) [KO:K01999 ]
H04402_00474 high-affinity branched-chain amino acid transport system permease protein LivH (TC 3.A.1.4.1) [KO:K01997 ]
H04402_00475 branched-chain amino acid transport system permease protein LivM (TC 3.A.1.4.1) [KO:K01998 ]
H04402_00476 branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) [KO:K01995 ]
H04402_00477 branched-chain amino acid transport ATP-binding protein LivF (TC 3.A.1.4.1) [KO:K01996 ]
H04402_03232 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) [KO:K15580 ]
H04402_03350 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA (TC 3.A.1.5.1) [KO:K15580 ]
H04402_03231 oligopeptide transport system permease protein OppB (TC 3.A.1.5.1) [KO:K15581 ]
H04402_03230 oligopeptide transport system permease protein OppC (TC 3.A.1.5.1) [KO:K15582 ]
H04402_00990 additional substrate-specific component CbiN of cobalt ECF transporter [KO:K02009 ]
H04402_00991 transmembrane component CbiQ of energizing module of cobalt ECF transporter [KO:K02008 ]
H04402_03550 transmembrane component of general energizing module of ECF transporters [KO:K16785 ]
H04402_01996 transmembrane component YkoC of energizing module of thiamin-regulated ECF transporter for HydroxyMethylPyrimidine [KO:K16785 ]
H04402_03552 ATPase component of general energizing module of ECF transporters [KO:K16786 ] [EC:7.-.-.-]
H04402_03551 ATPase component of general energizing module of ECF transporters [KO:K16787 ] [EC:7.-.-.-]
H04402_03490 cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) [KO:K09812 ]
H04402_01951 ABC-type multidrug/protein/lipid transport system, ATPase component [KO:K18887 ]
H04402_01950 ABC-type multidrug/protein/lipid transport system, ATPase component [KO:K18888 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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