Entry Name ABC transporters - Frankia alni
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Gene FRAAL3342 ssuA; Sulfonate transport system substrate-binding protein precursor [KO:K15553 ]
FRAAL0589 putative alkanesulfonate transport protein (ABC superfamily) [KO:K15553 ]
FRAAL0587 ssuC; alkanesulfonate transport protein (ABC superfamily, membrane) [KO:K15554 ]
FRAAL3341 ssuC; alkanesulfonate transport protein (ABC superfamily, membrane) (partial match) [KO:K15554 ]
FRAAL6313 putative molybdenum transport protein (ABC superfamily, atp_bind) (partial) [KO:K02017 ] [EC:7.3.2.5 ]
FRAAL6835 potI; Polyamine ABC-transporter integral membrane protein [KO:K11070 ]
FRAAL6834 potH; putrescine transport protein (ABC superfamily, membrane) [KO:K11071 ]
FRAAL6729 putative amino acid ABC transporter amino acid-binding protein [KO:K05845 ]
FRAAL6726 putative glycine/betaine/choline transport protein with CBS regulatory domain (ABC superfamily, atp_bind) (partial) [KO:K05847 ] [EC:7.6.2.9 ]
FRAAL0961 putative sugar transport ATP-hydrolyzing subunit (partial match) [KO:K10112 ] [EC:7.5.2.-]
FRAAL3205 ugpC; sn-glycerol 3-phosphate transport protein (ABC superfamily, atp_bind) [KO:K10112 ] [EC:7.5.2.-]
FRAAL3762 putative sugar transport protein (ABC superfamily; putative phenotypic repressor of mal operon (C-terminal) [KO:K10112 ] [EC:7.5.2.-]
FRAAL3765 putative Sugar ABC transporter (sugar-binding lipoprotein) (Maltodextrin-binding protein) [KO:K10236 ]
FRAAL3764 putative sugar transport protein (Sugar ABC transporter, permease protein) [KO:K10237 ]
FRAAL3763 putative sugar transport protein (ABC superfamily, membrane) [KO:K10238 ]
FRAAL0205 rbsC; high-affinity D-ribose transport protein (ABC superfamily, membrane) [KO:K10440 ]
FRAAL2526 Putative ribose transport system permease protein; putative membrane protein [KO:K10440 ]
FRAAL3204 hypothetical protein; putative signal peptide; putative Sugar binding protein of ABC transporter [KO:K05813 ]
FRAAL4366 Putative sugar ABC transporter, sugar-binding protein [KO:K05813 ]
FRAAL4369 ugpE; sn-glycerol 3-phosphate transport protein (ABC superfamily, membrane) [KO:K05815 ]
FRAAL6535 pstS; high-affinity phosphate transport protein (ABC superfamily) [KO:K02040 ]
FRAAL6534 pstC; high-affinity phosphate transport protein (ABC superfamily, membrane) [KO:K02037 ]
FRAAL6532 pstB; high-affinity phosphate transport protein (ABC superfamily, atp_bind) [KO:K02036 ] [EC:7.3.2.1 ]
FRAAL5714 putative glutamate binding protein of ABC transporter system [KO:K10005 ]
FRAAL5715 putative glutamate transport protein (ABC superfamily, membrane) [KO:K10006 ]
FRAAL0792 putative high-affinity branched chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
FRAAL4616 putative branched chain amino acid binding protein precursor. [KO:K01999 ]
FRAAL3527 putative branched-chain amino acid ABC transporter, amino acid-binding protein [KO:K01999 ]
FRAAL3554 putative Leu/Ile/Val-binding protein precursor (LIV-BP) [KO:K01999 ]
FRAAL3391 Putative branched-chain amino acid transport system substrate-binding protein precursor [KO:K01999 ]
FRAAL3582 Putative branched-chain amino acid transport system substrate-binding protein precursor [KO:K01999 ]
FRAAL1482 putative Leu/Ile/Val/Thr-binding protein precursor; putative signal peptide [KO:K01999 ]
FRAAL3365 Putative branched-chain amino acid transport system substrate-binding protein precursor [KO:K01999 ]
FRAAL4618 Putative branched-chain amino acid ABC transporter, perisplasmic amino acid-binding protein [KO:K01999 ]
FRAAL0726 braD; high-affinity branched-chain amino acid transport protein (ABC superfamily, membrane) [KO:K01997 ]
FRAAL0793 braE; high-affinity branched-chain amino acid transport system permease protein braE [KO:K01997 K01998 ]
FRAAL5035 putative High-affinity branched-chain amino acid transport system permease protein; putative membrane protein [KO:K01997 K01998 ]
FRAAL0727 braE; high-affinity branched-chain amino acid transport protein (ABC superfamily, membrane) [KO:K01998 ]
FRAAL0728 braF; branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01995 ]
FRAAL0794 braG; High-affinity branched-chain amino acid transport ATP-binding protein (partial match) [KO:K01995 K01996 ]
FRAAL1484 Branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01995 ]
FRAAL3090 putative high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01995 ]
FRAAL0729 braG; high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL3091 Branched-chain amino acid ABC transporter, ATP-binding protein [KO:K01996 ]
FRAAL3127 putative high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL3531 Putative ABC transport protein, ATP-binding component [KO:K01996 ]
FRAAL4862 livF; high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL5036 putative high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL2622 livF; high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL3360 livF; high-affinity branched-chain amino acid transport protein (ABC superfamily, atp_bind) [KO:K01996 ]
FRAAL4163 Putative iron-siderophore uptake system transmembrane component (ABC superfamily, membrane) [KO:K23186 ]
FRAAL4162 Putative iron-siderophore uptake system transmembrane component (ABC superfamily, membrane) [KO:K23187 ]
FRAAL5528 Putative ABC-transporter transmembrane component; putative membrane protein [KO:K18233 ]
FRAAL3509 Putative antibiotic ABC transporter protein, ATP-binding [KO:K18230 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
