KEGG   PATHWAY: lpar02010
Entry
lpar02010                   Pathway                                
Name
ABC transporters - Lentilactobacillus parabuchneri
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
lpar02010  ABC transporters
lpar02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Lentilactobacillus parabuchneri [GN:lpar]
Gene
FAM21731_01440  Spermidine/putrescine-binding periplasmic protein precursor [KO:K11069]
FAM21731_01441  Inner membrane ABC transporter permease protein YdcV [KO:K11070]
FAM21731_01442  Spermidine/putrescine transport system permease protein PotB [KO:K11071]
FAM21731_01443  Spermidine/putrescine import ATP-binding protein PotA [KO:K11072] [EC:7.6.2.11]
FAM21731_01752  Glycine betaine/carnitine transport binding protein GbuC precursor [KO:K02002]
FAM21731_01751  Glycine betaine/carnitine transport permease protein GbuB [KO:K02001]
FAM21731_01750  Glycine betaine/carnitine transport ATP-binding protein GbuA [KO:K02000] [EC:7.6.2.9]
FAM21731_01407  Carnitine transport binding protein OpuCC precursor [KO:K05845 K05846]
FAM21731_01406  Choline transport ATP-binding protein OpuBA [KO:K05847] [EC:7.6.2.9]
FAM21731_00933  D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
FAM21731_00851  sn-glycerol-3-phosphate-binding periplasmic protein UgpB precursor [KO:K05813]
FAM21731_00853  sn-glycerol-3-phosphate transport system permease protein UgpA [KO:K05814]
FAM21731_00852  Lactose transport system permease protein LacG [KO:K05815]
FAM21731_00854  sn-glycerol-3-phosphate import ATP-binding protein UgpC [KO:K05816] [EC:7.6.2.10]
FAM21731_01056  Phosphate-binding protein PstS 1 precursor [KO:K02040]
FAM21731_02033  Phosphate-binding protein PstS 1 precursor [KO:K02040]
FAM21731_01057  Phosphate transport system permease protein PstC [KO:K02037]
FAM21731_02034  Phosphate transport system permease protein PstC [KO:K02037]
FAM21731_01058  Phosphate transport system permease protein PstA [KO:K02038]
FAM21731_02035  Phosphate transport system permease protein PstA [KO:K02038]
FAM21731_01059  Phosphate import ATP-binding protein PstB 3 [KO:K02036] [EC:7.3.2.1]
FAM21731_01060  Phosphate import ATP-binding protein PstB 3 [KO:K02036] [EC:7.3.2.1]
FAM21731_02036  Phosphate import ATP-binding protein PstB 3 [KO:K02036] [EC:7.3.2.1]
FAM21731_02037  Phosphate import ATP-binding protein PstB 3 [KO:K02036] [EC:7.3.2.1]
FAM21731_01347  Phosphate-import protein PhnD precursor [KO:K02044]
FAM21731_01349  Phosphate-import permease protein PhnE [KO:K02042]
FAM21731_01350  Phosphate-import permease protein PhnE [KO:K02042]
FAM21731_01348  Glutamine transport ATP-binding protein GlnQ [KO:K02041] [EC:7.3.2.2]
FAM21731_00115  Glutamine transport system permease protein GlnP [KO:K10036 K10037]
FAM21731_00116  Arginine transport ATP-binding protein ArtM [KO:K10038] [EC:7.4.2.1]
FAM21731_01592  ABC transporter glutamine-binding protein GlnH precursor [KO:K10039]
FAM21731_01593  putative glutamine ABC transporter permease protein GlnM [KO:K10040]
FAM21731_01594  putative glutamine ABC transporter permease protein GlnP [KO:K10040]
FAM21731_01591  Glutamine transport ATP-binding protein GlnQ [KO:K10041] [EC:7.4.2.1]
FAM21731_01782  putative ABC transporter extracellular-binding protein YckB precursor [KO:K02424]
FAM21731_01783  L-cystine transport system permease protein TcyB [KO:K10009]
FAM21731_00152  Arginine transport system permease protein ArtQ [KO:K17077 K23059]
FAM21731_00151  Arginine transport ATP-binding protein ArtM [KO:K23060] [EC:7.4.2.1]
FAM21731_01499  Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein precursor [KO:K01999]
FAM21731_01500  High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01997]
FAM21731_01501  High-affinity branched-chain amino acid transport system permease protein LivH [KO:K01998]
FAM21731_01502  Lipopolysaccharide export system ATP-binding protein LptB [KO:K01995]
FAM21731_01503  High-affinity branched-chain amino acid transport ATP-binding protein LivF [KO:K01996]
FAM21731_01497  Membrane lipoprotein TpN32 precursor [KO:K02073]
FAM21731_00015  Methionine-binding lipoprotein MetQ precursor [KO:K02073]
FAM21731_01496  Methionine import system permease protein MetP [KO:K02072]
FAM21731_00016  Methionine import system permease protein MetP [KO:K02072]
FAM21731_01495  Methionine import ATP-binding protein MetN 2 [KO:K02071]
FAM21731_00017  Methionine import ATP-binding protein MetN 2 [KO:K02071]
FAM21731_00368  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_00394  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_01480  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_02300  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_00703  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_01567  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_00745  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_01602  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_01605  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_02132  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_00846  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_00875  Dipeptide-binding protein DppE precursor [KO:K15580]
FAM21731_00904  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_00939  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_00771  Oligopeptide-binding protein OppA precursor [KO:K15580]
FAM21731_01606  Oligopeptide transport system permease protein OppB [KO:K15581]
FAM21731_01607  Oligopeptide transport system permease protein OppC [KO:K15582]
FAM21731_01608  Oligopeptide transport ATP-binding protein OppD [KO:K15583]
FAM21731_01609  Oligopeptide transport ATP-binding protein OppF [KO:K10823]
FAM21731_01772  Biotin transporter BioY [KO:K03523]
FAM21731_01451  Putative HMP/thiamine permease protein YkoC [KO:K16785]
FAM21731_00628  Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
FAM21731_01505  Putative HMP/thiamine permease protein YkoC [KO:K16785]
FAM21731_01528  Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
FAM21731_01733  Energy-coupling factor transporter transmembrane protein EcfT [KO:K16785]
FAM21731_01529  Energy-coupling factor transporter ATP-binding protein EcfA1 [KO:K16786] [EC:7.-.-.-]
FAM21731_01731  Energy-coupling factor transporter ATP-binding protein EcfA1 [KO:K16786] [EC:7.-.-.-]
FAM21731_01530  Energy-coupling factor transporter ATP-binding protein EcfA3 [KO:K16787] [EC:7.-.-.-]
FAM21731_01732  Energy-coupling factor transporter ATP-binding protein EcfA2 [KO:K16787] [EC:7.-.-.-]
FAM21731_02457  Teichoic acid translocation permease protein TagG [KO:K09692]
FAM21731_02083  Teichoic acids export ATP-binding protein TagH [KO:K09693] [EC:7.5.2.4]
FAM21731_00762  putative multidrug resistance ABC transporter ATP-binding/permease protein YheI [KO:K18889]
FAM21731_00761  putative multidrug resistance ABC transporter ATP-binding/permease protein YheH [KO:K18890]
FAM21731_01379  Multidrug resistance ABC transporter ATP-binding and permease protein [KO:K18104] [EC:7.6.2.2]
FAM21731_00849  Putative multidrug export ATP-binding/permease protein [KO:K18887]
FAM21731_01359  Putative multidrug export ATP-binding/permease protein [KO:K18887]
FAM21731_01360  putative ABC transporter ATP-binding protein [KO:K18888]
FAM21731_00848  putative ABC transporter ATP-binding protein [KO:K18888]
FAM21731_01823  putative ABC transporter ATP-binding protein [KO:K16012]
FAM21731_01822  ATP-binding/permease protein CydD [KO:K16013]
FAM21731_00518  putative ABC transporter ATP-binding protein YheS [KO:K19350]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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