PATHWAY: lrh02010 Help
Entry
Name
ABC transporters - Lacticaseibacillus rhamnosus GG
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
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Pathway map
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Organism
Lacticaseibacillus rhamnosus GG [GN:
lrh ]
Gene
LGG_00173 tauA; ABC transporter, aliphatic sulfonates family ligand-binding protein [KO:K15551 ]
LGG_02435 ABC transporter, nitrate/sulfonate/bicarbonate-binding protein [KO:K15553 ]
LGG_00972 potD; ABC transporter, spermidine/putrescine-binding protein [KO:K11069 ]
LGG_00971 potC; ABC transporter, spermidine/putrescine transporter permease protein [KO:K11070 ]
LGG_00970 potB; ABC transporter, spermidine/putrescine transporter permease protein [KO:K11071 ]
LGG_02146 gbuC; ABC transporter, glycine/betaine/carnitine substrate-binding lipoprotein [KO:K02002 ]
LGG_02147 proW; ABC transporter, binding-protein-dependent transporter permeasecomponent [KO:K02001 ]
LGG_02148 proV; ABC transporter, glycine betaine/L-proline transporter ATP-binding protein [KO:K02000 ] [EC:7.6.2.9 ]
LGG_00076 opuCc; ABC transporter, glycine betaine/carnitine/choline-binding protein [KO:K05845 ]
LGG_00075 opuCd; Binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
LGG_00077 opuCb; Binding-protein-dependent transport systems inner membrane component [KO:K05846 ]
LGG_00078 opuCa; ABC transporter, Glycine betaine/L-proline transporter ATP-binding protein [KO:K05847 ] [EC:7.6.2.9 ]
LGG_00954 malK; ABC transporter, sugar transporter ATP-binding protein [KO:K10112 ] [EC:7.5.2.-]
LGG_02768 ugpB; ABC transporter, glycerol-3-phosphate-binding protein [KO:K05813 ]
LGG_02770 ugpA; ABC transporter, glycerol-3-phosphate transporter permease protein [KO:K05814 ]
LGG_02769 ugpE; ABC transporter, glycerol-3-phosphate transporter permease protein [KO:K05815 ]
LGG_00907 pstC; ABC transporter, phosphate transporter permease protein [KO:K02037 ]
LGG_00908 pstA; ABC transporter, phosphate transporter permease protein [KO:K02038 ]
LGG_02008 glnH; ABC transporter, amino acid-binding periplasmic protein [KO:K10039 ]
LGG_02007 glnP; ABC transporter, amino acid transporter permease protein [KO:K10040 ]
LGG_02006 glnP; ABC transporter, amino acid transporter permease protein [KO:K10040 ]
LGG_00573 yecS; ABC transporter, amino acid transporter permease protein [KO:K10009 ]
LGG_00481 ABC transporter, amino acid transporter permease protein [KO:K16958 ]
LGG_00480 ABC transporter, amino acid transporter permease protein [KO:K16959 ]
LGG_02849 glnQ; ABC transporter, amino acid transporter ATP-binding protein [KO:K17076 ]
LGG_00313 livJ; ABC transporter, branched-chain amino acid-binding protein [KO:K01999 ]
LGG_00314 livH; ABC transporter, branched-chain amino acid transporter permease protein [KO:K01997 ]
LGG_00315 livM; ABC transporter, branched-chain amino acid transporter permease protein [KO:K01998 ]
LGG_00316 livG; ABC transporter, branched-chain amino acid transporter ATP-binding protein [KO:K01995 ]
LGG_00317 livF; ABC transporter, branched-chain amino acid transporter ATP-binding protein [KO:K01996 ]
LGG_00500 metQ; ABC transporter, metal ion transporter periplasmic component/surface antigen [KO:K02073 ]
LGG_01195 metQ; ABC transporter, substrate-binding protein, NLPA lipoprotein [KO:K02073 ]
LGG_01196 metQ; ABC transporter, substrate-binding protein, NLPA lipoprotein [KO:K02073 ]
LGG_01945 oppA; ABC transporter, oligopeptide transporter periplasmic component [KO:K15580 ]
LGG_02801 oppA; ABC transporter, oligopeptide transporter periplasmic component [KO:K15580 ]
LGG_01944 oppB; ABC transporter, oligopeptide transported permease component [KO:K15581 ]
LGG_02065 oppB; ABC transporter, oligopeptide transporter permease protein [KO:K15581 ]
LGG_01943 oppC; ABC transporter, oligopeptide transported permease component [KO:K15582 ]
LGG_02064 oppC; ABC transporter, oligopeptide transporter permease protein [KO:K15582 ]
LGG_01941 oppD; ABC transporter, oligopeptide transporter ATP-binding protein [KO:K15583 ]
LGG_02063 oppD; ABC transporter, oligopeptide transporter ATP-binding protein [KO:K15583 ]
LGG_02062 oppF; ABC transporter, oligopeptide transporter ATP-binding protein [KO:K10823 ]
LGG_01940 oppF; ABC transporter, oligopeptide transporter ATP-binding protein [KO:K10823 ]
LGG_02420 mtsC; ABC transporter, iron transporter membrane protein [KO:K19976 ]
LGG_00365 cbiQ; ABC transporter, cobalt transporter permease component [KO:K16785 ]
LGG_02458 cbiO; ABC transporter, cobalt import transporter ATP-binding protein [KO:K16786 ] [EC:7.-.-.-]
LGG_02457 cbiO; ABC transporter, cobalt import transporter ATP-binding protein [KO:K16787 ] [EC:7.-.-.-]
LGG_00621 cylB; ABC transporter, multidrug transporter permease component [KO:K11051 ]
LGG_01795 ABC transporter, antimicrobial peptide transporter permease component [KO:K11632 ]
LGG_01634 mdlB; ABC transporter, multidrug/protein/lipid transporter ATP-binding and permease protein [KO:K18890 ]
LGG_00598 lmrC; ABC transporter, ATP-binding and permease protein [KO:K18891 ]
LGG_00599 lmrD; ABC transporter, ATP-binding and permease protein [KO:K18892 ]
LGG_01163 ycfI; ABC transporter, multidrug transporter ATPase and permease components [KO:K18887 ]
LGG_01164 yfiC; ABC transporter, multidrug transporter ATPase and permease components [KO:K18888 ]
LGG_02386 comA; Bacteriocin processing peptidase / Bacteriocin export ABC transporter [KO:K20344 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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