Entry Name ABC transporters - Mycobacterium liflandii
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Mycobacterium liflandii [GN:
mli ]
Gene MULP_03967 cysT; sulfate-transport integral membrane protein ABC transporter CysT [KO:K02046 ]
MULP_03966 cysW; sulfate-transport integral membrane protein ABC transporter CysW [KO:K02047 ]
MULP_02484 modA; molybdate ABC transporter substrate-binding protein [KO:K02020 ]
MULP_02485 modB; molybdenum-transport integral membrane protein ABC transporter ModB [KO:K02018 ]
MULP_00027 ABC-type proline/glycine betaine transport systems, permease domain protein [KO:K05846 ]
MULP_05552 proW; osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProW [KO:K05846 ]
MULP_05553 proZ; osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport integral membrane protein ABC transporter ProZ [KO:K05846 ]
MULP_00028 proV_1; osmoprotectant (glycine betaine/carnitine/choline/L-proline) transport ATP-binding protein ABC transporter ProV_1 [KO:K05847 ] [EC:7.6.2.9 ]
MULP_02810 sugar-transport ATP-binding protein ABC transporter [KO:K10112 ] [EC:7.5.2.-]
MULP_04377 sugC; sugar-transport ATP-binding protein ABC transporter SugC [KO:K10112 ] [EC:7.5.2.-]
MULP_04379 sugA; sugar-transport integral membrane protein ABC transporter SugA [KO:K10237 ]
MULP_04378 sugB; sugar-transport integral membrane protein ABC transporter SugB [KO:K10238 ]
MULP_01114 mkl; ribonucleotide-transport ATP-binding protein ABC transporter, Mkl [KO:K02065 ]
MULP_01392 phoS2_1; periplasmic phosphate-binding lipoprotein PhoS2_1 [KO:K02040 ]
MULP_04796 pstC2; phosphate-transport integral membrane ABC transporter PstC2 [KO:K02037 ]
MULP_05095 pstC2_1; phosphate-transport integral membrane ABC transporter PstC2_1 [KO:K02037 ]
MULP_04795 pstA1; phosphate-transport integral membrane ABC transporter PstA1 [KO:K02038 ]
MULP_05094 pstA; phosphate-transport integral membrane ABC transporter, PstA [KO:K02038 ]
MULP_05429 dppB; dipeptide-transport integral membrane protein ABC transporter DppB [KO:K15581 ]
MULP_05428 dppC; dipeptide-transport integral membrane protein ABC transporter DppC [KO:K15582 ]
MULP_04304 oppB; oligopeptide-transport integral membrane protein ABC transporter OppB [KO:K13890 ]
MULP_04305 oppC; oligopeptide-transport integral membrane protein ABC transporter OppC [KO:K13891 ]
MULP_04306 oppD; oligopeptide-transport ATP-binding protein ABC transporter OppD [KO:K13892 ]
MULP_05612 rfbD; O-antigen/lipopolysaccharide transport integral membrane protein ABC transporter RfbD [KO:K09690 ]
MULP_05610 rfbE; O-antigen/lipopolysaccharide transport ATP-binding protein ABC transporter RfbE [KO:K09691 ] [EC:7.5.2.14 ]
MULP_02200 antibiotic-transport integral membrane leucine, alanine and valine rich protein ABC transporter [KO:K16905 ]
MULP_02199 antibiotic-transport integral membrane leucine and valine rich protein ABC transporter [KO:K16906 ]
MULP_04202 transmembrane ATP-binding protein ABC transporter [KO:K14698 ] [EC:7.-.-.-]
MULP_04201 transmembrane ATP-binding protein ABC transporter [KO:K14699 ] [EC:7.-.-.-]
MULP_03194 cydC; cytochrome transmembrane ATP-binding protein ABC transporter CydC [KO:K16012 ]
MULP_03193 cydD; cytochrome transmembrane ATP-binding protein ABC transporter CydD [KO:K16013 ]
MULP_02443 drug-transport transmembrane ATP-binding protein ABC transporter [KO:K02471 ]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
