PATHWAY: mrh02010 Help
Entry
Name
ABC transporters - Mycolicibacterium rhodesiae
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Mycolicibacterium rhodesiae [GN:
mrh ]
Gene
MycrhN_4305 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15552 ]
MycrhN_2943 ABC transporter, substrate-binding protein, aliphatic sulfonates family [KO:K15553 ]
MycrhN_5058 ABC transporter, substrate-binding protein, aliphatic sulfonates family [KO:K15553 ]
MycrhN_2937 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15554 ]
MycrhN_5060 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [KO:K15554 ]
MycrhN_5565 molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
MycrhN_5036 ABC-type spermidine/putrescine transport system, permease component II [KO:K11070 ]
MycrhN_5035 ABC-type spermidine/putrescine transport system, permease component I [KO:K11071 ]
MycrhN_1996 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [KO:K05845 ]
MycrhN_5075 periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [KO:K05845 ]
MycrhN_1998 ABC-type proline/glycine betaine transport system, permease component [KO:K05846 ]
MycrhN_1999 ABC-type proline/glycine betaine transport system, permease component [KO:K05846 ]
MycrhN_5076 ABC-type proline/glycine betaine transport system, permease component [KO:K05846 ]
MycrhN_5078 ABC-type proline/glycine betaine transport system, permease component [KO:K05846 ]
MycrhN_0009 ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067 ]
MycrhN_0006 ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067 ]
MycrhN_0007 ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067 ]
MycrhN_0008 ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067 ]
MycrhN_0011 ABC-type transport system involved in resistance to organic solvents, periplasmic component [KO:K02067 ]
MycrhN_2997 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_4032 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_4033 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_4180 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_4181 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_2600 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_2335 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_2336 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_2998 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_1587 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_1588 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_3577 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_3576 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_0013 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_0495 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_3168 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_0012 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_2599 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_3167 ABC-type transport system involved in resistance to organic solvents, permease component [KO:K02066 ]
MycrhN_0747 ABC-type transport system involved in resistance to organic solvents, ATPase component [KO:K02065 ]
MycrhN_0845 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K10036 K10037 ]
MycrhN_5597 periplasmic component of amino acid ABC-type transporter/signal transduction system [KO:K10005 ]
MycrhN_5598 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K10006 ]
MycrhN_5599 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K10007 ]
MycrhN_2025 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family [KO:K02424 K10009 ]
MycrhN_4598 ABC-type branched-chain amino acid transport system, periplasmic component [KO:K01999 ]
MycrhN_4599 branched-chain amino acid ABC-type transport system, permease component [KO:K01997 ]
MycrhN_4600 ABC-type branched-chain amino acid transport system, permease component [KO:K01998 ]
MycrhN_4601 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01995 ]
MycrhN_4602 ABC-type branched-chain amino acid transport systems, ATPase component [KO:K01996 ]
MycrhN_3767 ABC-type dipeptide/oligopeptide/nickel transport system, permease component [KO:K13890 ]
MycrhN_3766 ABC-type dipeptide/oligopeptide/nickel transport system, permease component [KO:K13891 ]
MycrhN_1966 ABC-type polysaccharide/polyol phosphate export systems, permease component [KO:K09690 ]
MycrhN_4327 ABC-type multidrug transport system, ATPase and permease component [KO:K14698 ] [EC:7.-.-.-]
MycrhN_4326 ABC-type multidrug transport system, ATPase and permease component [KO:K14699 ] [EC:7.-.-.-]
MycrhN_3752 ABC-type multidrug transport system, ATPase and permease component [KO:K18887 ]
MycrhN_4582 fused ATPase/permease component of ABC-type transporter involved in cytochrome bd biogenesis [KO:K16012 ]
MycrhN_4583 cysteine export CydDC family ABC transporter permease subunit/ATP-binding protein CydD [KO:K16013 ]
MycrhN_4806 ABC-type uncharacterized transport system, permease and ATPase component [KO:K02471 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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