KEGG   PATHWAY: ndk03060
Entry
ndk03060                    Pathway                                
Name
Protein export - Nocardioides dokdonensis
Description
The protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the general protein export system that transports newly synthesized proteins into or across the cell membrane. The translocation channel is formed from a conserved trimeric membrane protein complex, called the Sec61/SecY complex. The twin-arginine translocation (Tat) pathway is another protein transport system that transports folded proteins in bacteria, archaea, and chloroplasts. Many Tat systems comprise three functionally different membrane proteins, TatA, TatB, and TatC, but TatA and TatE seem to have overlapping functions, with TatA having by far the more important role.
Class
Genetic Information Processing; Folding, sorting and degradation
Pathway map
ndk03060  Protein export
ndk03060

Other DBs
GO: 0043952 0043953
Organism
Nocardioides dokdonensis [GN:ndk]
Gene
I601_0454  preprotein translocase subunit SecY [KO:K03076]
I601_0741  preprotein translocase subunit SecE [KO:K03073]
I601_3430  preprotein translocase subunit SecG [KO:K03075]
I601_2972  preprotein translocase subunit SecD [KO:K03072]
I601_2973  preprotein translocase subunit SecF [KO:K03074]
I601_3378  bifunctional preprotein translocase subunit SecD/SecF [KO:K12257]
I601_2971  preprotein translocase subunit YajC [KO:K03210]
I601_1269  yidC; Membrane protein insertase YidC [KO:K03217]
I601_0133  preprotein translocase subunit SecA [KO:K03070] [EC:7.4.2.8]
I601_2525  ffh; Signal recognition particle protein [KO:K03106] [EC:3.6.5.4]
I601_2521  ftsY; Signal recognition particle receptor FtsY [KO:K03110]
I601_2679  arsA_4; Arsenical pump-driving ATPase [KO:K01551] [EC:7.3.2.7 7.3.-.-]
I601_0867  arsA_1; Arsenical pump-driving ATPase [KO:K01551] [EC:7.3.2.7 7.3.-.-]
I601_3308  tatAy; Sec-independent protein translocase protein TatAy [KO:K03116]
I601_0129  tatB; Sec-independent protein translocase protein TatB [KO:K03117]
I601_3307  tatC; Sec-independent protein translocase protein TatC [KO:K03118]
I601_2533  lepB_1; Signal peptidase I [KO:K03100] [EC:3.4.21.89]
I601_3981  lepB_2; Signal peptidase I [KO:K03100] [EC:3.4.21.89]
I601_2742  lipoprotein signal peptidase [KO:K03101] [EC:3.4.23.36]
I601_4118  lipoprotein signal peptidase [KO:K03101] [EC:3.4.23.36]
I601_1049  sipW_1; Signal peptidase I W [KO:K13280] [EC:3.4.21.89]
I601_2795  sipW_2; Signal peptidase I W [KO:K13280] [EC:3.4.21.89]
Reference
  Authors
Dalbey RE, Robinson C.
  Title
Protein translocation into and across the bacterial plasma membrane and the plant thylakoid membrane.
  Journal
Trends Biochem Sci 24:17-22 (1999)
DOI:10.1016/S0968-0004(98)01333-4
Reference
  Authors
Berks BC, Sargent F, Palmer T.
  Title
The Tat protein export pathway.
  Journal
Mol Microbiol 35:260-74 (2000)
DOI:10.1046/j.1365-2958.2000.01719.x
Reference
  Authors
Wexler M, Sargent F, Jack RL, Stanley NR, Bogsch EG, Robinson C, Berks BC, Palmer T.
  Title
TatD is a cytoplasmic protein with DNase activity. No requirement for TatD family proteins in sec-independent protein export.
  Journal
J Biol Chem 275:16717-22 (2000)
DOI:10.1074/jbc.M000800200
Reference
  Authors
Jongbloed JD, Martin U, Antelmann H, Hecker M, Tjalsma H, Venema G, Bron S, van Dijl JM, Muller J.
  Title
TatC is a specificity determinant for protein secretion via the twin-arginine translocation pathway.
  Journal
J Biol Chem 275:41350-7 (2000)
DOI:10.1074/jbc.M004887200
Reference
  Authors
Rapoport TA
  Title
Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes.
  Journal
Nature 450:663-9 (2007)
DOI:10.1038/nature06384
Reference
  Authors
Flower AM
  Title
The SecY translocation complex: convergence of genetics and structure.
  Journal
Trends Microbiol 15:203-10 (2007)
DOI:10.1016/j.tim.2007.03.001
Reference
  Authors
Osborne AR, Rapoport TA, van den Berg B
  Title
Protein translocation by the Sec61/SecY channel.
  Journal
Annu Rev Cell Dev Biol 21:529-50 (2005)
DOI:10.1146/annurev.cellbio.21.012704.133214
Reference
  Authors
Paetzel M, Karla A, Strynadka NC, Dalbey RE
  Title
Signal peptidases.
  Journal
Chem Rev 102:4549-80 (2002)
DOI:10.1021/cr010166y
Reference
  Authors
Paetzel M, Dalbey RE, Strynadka NC
  Title
The structure and mechanism of bacterial type I signal peptidases. A novel antibiotic target.
  Journal
Pharmacol Ther 87:27-49 (2000)
DOI:10.1016/S0163-7258(00)00064-4
Reference
  Authors
Ng SY, Chaban B, VanDyke DJ, Jarrell KF
  Title
Archaeal signal peptidases.
  Journal
Microbiology 153:305-14 (2007)
DOI:10.1099/mic.0.2006/003087-0
Reference
  Authors
Desvaux M, Hebraud M, Talon R, Henderson IR
  Title
Secretion and subcellular localizations of bacterial proteins: a semantic awareness issue.
  Journal
Trends Microbiol 17:139-45 (2009)
DOI:10.1016/j.tim.2009.01.004
Reference
  Authors
Nakatogawa H, Murakami A, Ito K
  Title
Control of SecA and SecM translation by protein secretion.
  Journal
Curr Opin Microbiol 7:145-50 (2004)
DOI:10.1016/j.mib.2004.01.001
KO pathway
ko03060   
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