KEGG   PATHWAY: ome02010
Entry
ome02010                    Pathway                                
Name
ABC transporters - Oleiphilus messinensis
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
ome02010  ABC transporters
ome02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Oleiphilus messinensis [GN:ome]
Gene
OLMES_0940  nitrate transport ATP-binding protein [KO:K15576]
OLMES_1392  nitrate transporter component, nrtA [KO:K15576]
OLMES_0939  nitrate/sulfonate/bicarbonate ABC transporter permease [KO:K15577]
OLMES_1391  nitrate ABC transporter permease [KO:K15577]
OLMES_0938  nitrate transport ATP-binding subunits C and D [KO:K15578] [EC:7.3.2.4]
OLMES_1390  nitrate ABC transporter ATP-binding protein [KO:K15578] [EC:7.3.2.4]
OLMES_3951  ABC transporter sulfonate/nitrate transport system substrate-binding protein [KO:K15553]
OLMES_3950  binding-protein dependent transport system inner membrane protein [KO:K15554]
OLMES_3948  nitrate/sulfonate/bicarbonate ABC transporter ATPase [KO:K15555] [EC:7.6.2.14]
OLMES_2804  molybdenum ABC transporter periplasmic binding protein [KO:K02020]
OLMES_2803  molybdate ABC transporter inner membrane subunit [KO:K02018]
OLMES_2802  molybdate ABC transporter ATPase [KO:K02017] [EC:7.3.2.5]
OLMES_3074  Fe3+ ABC transporter periplasmic protein [KO:K02012]
OLMES_3994  2-aminoethylphosphonate ABC transporter substrate-binding protein [KO:K02012]
OLMES_3075  ABC-type Fe3+ transport system, permease component [KO:K02011]
OLMES_3996  Fe3+ ABC transporter permease [KO:K02011]
OLMES_1209  ABC transporter ATP-binding component [KO:K02010] [EC:7.2.2.7]
OLMES_3995  ABC transporter ATPase [KO:K02010] [EC:7.2.2.7]
OLMES_4173  spermidine/putrescine-binding periplasmic protein [KO:K11069]
OLMES_2918  spermidine/putrescine-binding periplasmic protein [KO:K11069]
OLMES_5219  spermidine/putrescine-binding periplasmic protein-like [KO:K11069]
OLMES_4172  spermidine/putrescine ABC transporter membrane protein [KO:K11070]
OLMES_2795  spermidine/putrescine ABC transporter permease II [KO:K11070]
OLMES_4171  spermidine/putrescine ABC transporter membrane protein [KO:K11071]
OLMES_4170  putrescine/spermidine ABC transporter ATPase [KO:K11072] [EC:7.6.2.11]
OLMES_0498  glycine betaine ABC transporter substrate-binding protein [KO:K02002]
OLMES_4037  ABC superfamily (glycine/betaine/proline transport protein) [KO:K02002]
OLMES_4036  ABC-type proline/glycine betaine transport system, permease component [KO:K02001]
OLMES_4035  ABC glycine/betaine/L-proline transporter, ATP-binding subunit proV [KO:K02000] [EC:7.6.2.9]
OLMES_1901  toluene tolerance family protein [KO:K07323]
OLMES_1900  HCH family ABC transporter periplasmic protein [KO:K02067]
OLMES_1899  HCH family ABC transporter permease [KO:K02066]
OLMES_1902  NTP binding protein [KO:K07122]
OLMES_1898  HCH family ABC transporter ATPase [KO:K02065]
OLMES_3704  ABC-type transport system, periplasmic component/surface lipoprotein [KO:K07335]
OLMES_3706  ABC transporter permease [KO:K23535]
OLMES_3705  ABC-type transport system, permease component [KO:K23536]
OLMES_3707  ABC transporter ATPase [KO:K23537]
OLMES_3388  periplasmic binding protein/LacI transcriptional regulator [KO:K10439]
OLMES_1760  family 1 extracellular solute-binding protein [KO:K17321]
OLMES_0579  sugar ABC transporter periplasmic sugar-binding protein [KO:K17321]
OLMES_4789  phosphate ABC transporter substrate-binding protein [KO:K02040]
OLMES_0240  phosphate ABC transporter, periplasmic phosphate-binding protein [KO:K02040]
OLMES_0501  phosphate binding protein [KO:K02040]
OLMES_4788  ABC transporter permease [KO:K02037]
OLMES_0235  phosphate ABC superfamily ATP binding cassette transporter, permease protein [KO:K02037]
OLMES_0502  phosphate ABC transporter, PhoT family TC 3.A.1.7.1, membrane protein 1 [KO:K02037]
OLMES_4787  phosphate ABC transporter permease [KO:K02038]
OLMES_0234  phosphate ABC transporter permease component [KO:K02038]
OLMES_0503  phosphate ABC transporter permease [KO:K02038]
OLMES_4786  phosphate transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
OLMES_0233  phosphate ABC superfamily ATP binding cassette transporter, ABC protein [KO:K02036] [EC:7.3.2.1]
OLMES_0504  ABC transporter [KO:K02036] [EC:7.3.2.1]
OLMES_1561  phosphonate ABC transporter, periplasmic phosphonate-binding protein [KO:K02044]
OLMES_5444  phnD; phosphonate ABC transporter periplasmic binding subunit [KO:K02044]
OLMES_0301  phosphate/phosphite/phosphonate ABC transporter periplasmic binding protein [KO:K02044]
OLMES_1559  phosphonate ABC transporter, inner membrane subunit [KO:K02042]
OLMES_5443  phnE; phosphonate ABC transporter permease [KO:K02042]
OLMES_1560  ABC transporter [KO:K02041] [EC:7.3.2.2]
OLMES_5445  phnC; phosphonate ABC transporter ATP-binding subunit [KO:K02041] [EC:7.3.2.2]
OLMES_0162  amino acid ABC transporter periplasmic protein [KO:K09969]
OLMES_0163  amino acid ABC transporter permease [KO:K09970]
OLMES_0164  ABC transporter permease [KO:K09971]
OLMES_0165  ABC transporter, ATP-binding protein [KO:K09972] [EC:7.4.2.1]
OLMES_1567  arginine transport protein (ABC superfamily) [KO:K10022]
OLMES_1565  ABC-type arginine/histidine transport system, permease component [KO:K10023]
OLMES_1566  arginine/ornithine ABC transporter permease protein AotQ [KO:K10024]
OLMES_1568  amino acid ABC transporter ATP-binding protein [KO:K10025] [EC:7.4.2.1]
OLMES_1509  livK; leucine ABC transporter substrate-binding subunit [KO:K01999]
OLMES_4165  extracellular ligand-binding receptor [KO:K01999]
OLMES_1508  livH; leucine/isoleucine/valine transporter permease subunit [KO:K01997]
OLMES_1507  livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998]
OLMES_1506  livG; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995]
OLMES_1505  livF; leucine/isoleucine/valine transporter subunit [KO:K01996]
OLMES_0645  urtB; urea ABC transporter substrate-binding protein [KO:K11959]
OLMES_0646  urtA; urea ABC transporter permease [KO:K11960]
OLMES_0647  urtC; urea ABC transporter permease [KO:K11961]
OLMES_0648  urtD; urea ABC transporter ATP-binding protein [KO:K11962]
OLMES_0649  urtE; urea ABC transporter ATP-binding protein [KO:K11963]
OLMES_3043  ABC transporter substrate-binding protein [KO:K13893]
OLMES_3044  extracellular solute-binding protein, family 5 [KO:K13893]
OLMES_3045  oligopeptide transport system permease protein OppB [KO:K13894]
OLMES_3046  peptide ABC transporter permease [KO:K13895]
OLMES_3047  ABC transporter [KO:K13896]
OLMES_2586  ABC transporter substrate-binding protein [KO:K06858]
OLMES_2186  ABC-type Zn2+ transport system, periplasmic component/surface adhesin [KO:K09815]
OLMES_4075  zinc ABC transporter periplasmic protein/surface adhesin [KO:K09815]
OLMES_0308  zinc ABC transporter permease [KO:K09816]
OLMES_4073  zinc ABC transporter permease [KO:K09816]
OLMES_0309  zinc ABC transporter ATPase [KO:K09817] [EC:7.2.2.20]
OLMES_4074  zinc import ATP-binding protein [KO:K09817] [EC:7.2.2.20]
OLMES_0918  ABC-type transporter, permease component [KO:K09690]
OLMES_0917  ABC transporter-like protein [KO:K09691] [EC:7.5.2.14]
OLMES_2070  outer membrane-specific lipoprotein transporter subunit LolE [KO:K09808]
OLMES_2071  lipoprotein transporter ATP-binding subunit [KO:K09810] [EC:7.6.2.-]
OLMES_3216  inner membrane protein [KO:K02196]
OLMES_3217  heme exporter protein CcmC [KO:K02195]
OLMES_3218  heme exporter protein CcmB [KO:K02194]
OLMES_3219  heme exporter protein A [KO:K02193] [EC:7.6.2.5]
OLMES_3879  outer membrane lipopolysaccharide export porin [KO:K07091]
OLMES_3589  outer membrane lipopolysaccharide export porin [KO:K07091]
OLMES_3878  outer membrane lipopolysaccharide export porin [KO:K11720]
OLMES_3588  outer membrane lipopolysaccharide export porin [KO:K11720]
OLMES_1893  ABC transporter, ATP-binding protein [KO:K06861] [EC:7.5.2.5]
OLMES_0345  cell division protein [KO:K09811]
OLMES_0344  cell division ATPase [KO:K09812]
OLMES_2076  lipid A export ATP-binding/permease protein MsbA [KO:K11085] [EC:7.5.2.6]
OLMES_2294  Fe-S cluster assembly ABC transporter permease/ATPase [KO:K24821]
OLMES_0907  type I secretion system ATPase [KO:K12536]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
LinkDB

DBGET integrated database retrieval system