PATHWAY: pman02010 Help
Entry
Name
ABC transporters - Pseudomonas mandelii
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
BRITE hierarchy
Pathway map
Ortholog table
Other DBs
Organism
Pseudomonas mandelii [GN:
pman ]
Gene
OU5_3267 binding-protein dependent transport system inner membrane protein [KO:K02046 ]
OU5_3229 taurine ABC transporter, periplasmic binding protein [KO:K15551 ]
OU5_3231 binding-protein dependent transport system inner membrane protein [KO:K15552 ]
OU5_3753 ABC transporter, substrate-binding protein, aliphatic sulfonates [KO:K15553 ]
OU5_3755 binding-protein dependent transport system inner membrane protein [KO:K15554 ]
OU5_0167 modA; molybdenum ABC transporter, periplasmic molybdate-binding protein [KO:K02020 ]
OU5_0166 cysT; molybdate ABC transporter, permease protein [KO:K02018 ]
OU5_3799 putative cation ABC transport system, substrate-binding protein [KO:K02012 ]
OU5_2925 iron(III) ABC transporter, periplasmic-binding protein [KO:K02012 ]
OU5_3728 binding-protein dependent transport system inner membrane protein [KO:K02011 ]
OU5_2926 fbpB; iron(III)-transport system permease protein [KO:K02011 ]
OU5_0506 binding-protein dependent transport system inner membrane protein [KO:K02011 ]
OU5_0044 binding-protein dependent transport system inner membrane protein [KO:K11070 ]
OU5_0045 binding-protein dependent transport system inner membrane protein [KO:K11071 ]
OU5_0712 putative spermidine/putrescine transport system substrate-binding protein [KO:K11073 ]
OU5_3533 putrescine ABC transporter, periplasmic putrescine-binding protein [KO:K11073 ]
OU5_3766 binding-protein dependent transport system inner membrane protein [KO:K11074 ]
OU5_5939 binding-protein dependent transport system inner membrane protein [KO:K11074 ]
OU5_3765 potB; putrescine ABC transporter, permease protein [KO:K11075 ]
OU5_5940 binding-protein dependent transport system inner membrane protein [KO:K11075 ]
OU5_0750 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_3423 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_5222 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_3938 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_3947 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_3093 substrate-binding region of ABC-type glycine betaine transport system [KO:K02002 ]
OU5_3100 putative histidine transport system, substrate-binding protein [KO:K02002 ]
OU5_3937 binding-protein dependent transport system inner membrane protein [KO:K02001 ]
OU5_3099 putative histidine ABC transport system, membrane protein [KO:K02001 ]
OU5_2604 substrate-binding region of ABC-type glycine betaine transport system [KO:K05845 ]
OU5_2603 binding-protein dependent transport system inner membrane protein [KO:K05846 ]
OU5_2605 glycine betaine/carnitine/choline ABC transporter, permease protein [KO:K05846 ]
OU5_0312 binding-protein dependent transport system inner membrane protein [KO:K10228 ]
OU5_0311 binding-protein dependent transport system inner membrane protein [KO:K10229 ]
OU5_2540 toluene tolerance ABC transporter, periplasmic substrate-binding protein [KO:K02067 ]
OU5_2541 toluene tolerance ABC efflux transporter, permease [KO:K02066 ]
OU5_4911 binding-protein dependent transport system inner membrane protein [KO:K17316 ]
OU5_4912 glucose ABC transporter, permease protein, putative [KO:K17317 ]
OU5_5667 periplasmic binding protein/LacI transcriptional regulator [KO:K10439 ]
OU5_1785 araF; L-arabinose ABC transport system, substrate-binding periplasmic protein [KO:K10537 ]
OU5_0137 periplasmic binding protein/LacI transcriptional regulator [KO:K10543 ]
OU5_0760 sugar ABC transporter, periplasmic sugar-binding protein [KO:K17213 ]
OU5_0759 putative ATP-binding component of ABC transporter [KO:K17215 ]
OU5_1214 binding-protein dependent transport system inner membrane protein [KO:K17322 ]
OU5_1213 putative ABC transport protein, inner membrane component [KO:K17323 ]
OU5_3548 putative phosphate ABC transport system, periplasmic substrate-binding protein [KO:K02040 ]
OU5_3549 binding-protein dependent transport system inner membrane protein [KO:K02037 ]
OU5_P0290 ptxB; putative phosphite transport system-binding protein ptxB [KO:K02044 ]
OU5_1076 phosphonate ABC transporter, inner membrane subunit [KO:K02042 ]
OU5_2204 hisQ; histidine ABC transport system, permease protein [KO:K10016 ]
OU5_2203 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K10014 ]
OU5_4747 amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K10001 ]
OU5_4746 gltJ; glutamate/aspartate ABC transport system, permease [KO:K10003 ]
OU5_2430 putative amino acid ABC transport system, membrane protein [KO:K09970 ]
OU5_4993 lysine-arginine-ornithine-binding periplasmic protein [KO:K10022 ]
OU5_2438 lysine-arginine-ornithine-binding periplasmic protein [KO:K10022 ]
OU5_5878 lysine-arginine-ornithine-binding periplasmic protein [KO:K10022 ]
OU5_2166 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K01999 ]
OU5_2167 livH; branched-chain amino acid ABC transporter, permease protein [KO:K01997 ]
OU5_2168 leucine/isoleucine/valine transporter permease subunit [KO:K01998 ]
OU5_2169 leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995 ]
OU5_2899 livF2; high-affinity branched-chain amino acid transport ATP-binding protein [KO:K01996 ]
OU5_3251 binding-protein dependent transport system inner membrane protein [KO:K02072 ]
OU5_3380 binding-protein dependent transport system inner membrane protein [KO:K02072 ]
OU5_2863 branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein [KO:K11959 ]
OU5_2590 dipeptide ABC transporter, periplasmic dipeptide-binding protein, putative [KO:K12368 ]
OU5_2591 dppA2; dipeptide ABC transport system, substrate-binding protein [KO:K12368 ]
OU5_2594 binding-protein dependent transport system inner membrane protein [KO:K12369 ]
OU5_2596 dppD; dipeptide ABC transport system, ATP-binding protein [KO:K12371 ]
OU5_0681 binding-protein dependent transport system inner membrane protein [KO:K13894 ]
OU5_0115 binding-protein dependent transport system inner membrane protein [KO:K13894 ]
OU5_0682 binding-protein dependent transport system inner membrane protein [KO:K13895 ]
OU5_0114 binding-protein dependent transport system inner membrane protein [KO:K13895 ]
OU5_5493 lipoprotein releasing system transmembrane protein LolC [KO:K09808 ]
OU5_5495 lipoprotein releasing system transmembrane protein LolE [KO:K09808 ]
OU5_5494 lipoprotein releasing system, ATP-binding protein [KO:K09810 ] [EC:7.6.2.-]
OU5_1418 pvdE38; Putative pyoverdine ABC export system permease/ATP-binding protein [KO:K06160 ]
Compound
C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference
Authors
Tomii K, Kanehisa M.
Title
A comparative analysis of ABC transporters in complete microbial genomes.
Journal
Reference
Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal
Reference
Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal
Reference
Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal
Reference
Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal
Reference
Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal
Reference
Authors
Richard-Fogal CL, Frawley ER, Kranz RG
Title
Topology and function of CcmD in cytochrome c maturation.
Journal
Reference
Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal
Reference
Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal
Reference
Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal
Reference
Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal
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