KEGG   PATHWAY: pput02010
Entry
pput02010                   Pathway                                
Name
ABC transporters - Pseudomonas putida H8234
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
pput02010  ABC transporters
pput02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Pseudomonas putida H8234 [GN:pput]
Gene
L483_23835  sulfate ABC transporter substrate-binding protein [KO:K02048]
L483_31025  ABC transporter permease [KO:K23163]
L483_31020  sulfate/thiosulfate transporter subunit [KO:K02046]
L483_31015  cysW; sulfate/thiosulfate transporter permease subunit [KO:K02047]
L483_31010  sulfate ABC transporter ATP-binding protein [KO:K02045] [EC:7.3.2.3]
L483_00905  tauA; taurine ABC transporter substrate-binding protein [KO:K15551]
L483_00895  taurine ABC transporter permease [KO:K15552]
L483_00900  tauB; taurine ABC transporter ATP-binding protein [KO:K10831] [EC:7.6.2.7]
L483_13700  ABC transporter substrate-binding protein [KO:K15553]
L483_00775  nitrate ABC transporter substrate-binding protein [KO:K15553]
L483_00925  ABC transporter substrate-binding protein [KO:K15553]
L483_09585  ABC transporter substrate-binding protein [KO:K15553]
L483_09590  ABC transporter substrate-binding protein [KO:K15553]
L483_18480  ABC transporter substrate-binding protein [KO:K15553]
L483_10175  ABC transporter substrate-binding protein [KO:K15553]
L483_13525  sulfonate ABC transporter substrate-binding protein [KO:K15553]
L483_00525  nitrate ABC transporter substrate-binding protein [KO:K15553]
L483_00740  nitrate ABC transporter substrate-binding protein [KO:K15553]
L483_00770  ABC transporter permease [KO:K15554]
L483_00935  ssuC; sulfonate ABC transporter [KO:K15554]
L483_10060  ABC transporter permease [KO:K15554]
L483_10065  ABC transporter permease [KO:K15554]
L483_00535  ABC transporter permease [KO:K15554]
L483_00745  taurine ABC transporter permease [KO:K15554]
L483_00940  ssuB; aliphatic sulfonate ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
L483_00765  spermidine/putrescine ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
L483_10055  ATP-binding protein [KO:K15555] [EC:7.6.2.14]
L483_00530  tauB; taurine ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
L483_00750  spermidine/putrescine ABC transporter ATP-binding protein [KO:K15555] [EC:7.6.2.14]
L483_21460  molybdate ABC transporter substrate-binding protein [KO:K02020]
L483_21465  molybdenum ABC transporter permease [KO:K02018]
L483_21470  molybdenum ABC transporter ATP-binding protein [KO:K02017] [EC:7.3.2.5]
L483_29580  sugar ABC transporter substrate-binding protein [KO:K02012]
L483_30810  phosphonate ABC transporter substrate-binding protein [KO:K02012]
L483_31150  iron ABC transporter substrate-binding protein [KO:K02012]
L483_29585  iron ABC transporter permease [KO:K02011]
L483_30815  phosphonate ABC transporter permease [KO:K02011]
L483_31145  FeT family ferric iron ABC transporter permease [KO:K02011]
L483_30820  sulfate ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
L483_26075  iron ABC transporter ATP-binding protein [KO:K02010] [EC:7.2.2.7]
L483_21940  ABC transporter substrate-binding protein [KO:K11069]
L483_21930  polyamine ABC transporter permease [KO:K11070]
L483_21935  spermidine/putrescine ABC transporter permease [KO:K11071]
L483_21925  spermidine/putrescine ABC transporter ATP-binding protein [KO:K11072] [EC:7.6.2.11]
L483_31070  putrescine/spermidine ABC transporter substrate-binding protein [KO:K11073]
L483_31075  putrescine/spermidine ABC transporter substrate-binding protein [KO:K11073]
L483_17730  ABC transporter substrate-binding protein [KO:K11073]
L483_08770  putrescine/spermidine ABC transporter substrate-binding protein [KO:K11073]
L483_27655  ABC transporter substrate-binding protein [KO:K11073]
L483_31840  ABC transporter substrate-binding protein [KO:K11073]
L483_19350  polyamine ABC transporter substrate-binding protein [KO:K11073]
L483_04425  ABC transporter substrate-binding protein [KO:K11073]
L483_31055  putrescine/spermidine ABC transporter permease [KO:K11074]
L483_31060  putrescine/spermidine ABC transporter permease [KO:K11075]
L483_31065  potG; putrescine/spermidine ABC transporter ATP-binding protein [KO:K11076] [EC:7.6.2.16]
L483_18640  histidine ABC transporter substrate-binding protein [KO:K02002]
L483_01510  glycine/betaine ABC transporter substrate-binding protein [KO:K02002]
L483_01545  glycine/betaine ABC transporter substrate-binding protein [KO:K02002]
L483_06235  glycine/betaine ABC transporter substrate-binding protein [KO:K02002]
L483_00025  glycine/betaine ABC transporter substrate-binding protein [KO:K02002]
L483_18645  ABC transporter permease [KO:K02001]
L483_01505  ABC transporter permease [KO:K02001]
L483_01500  ABC transporter ATP-binding protein [KO:K02000] [EC:7.6.2.9]
L483_04405  glycine/betaine ABC transporter substrate-binding protein [KO:K05845]
L483_04400  choline ABC transporter permease [KO:K05846]
L483_04410  glycine/betaine ABC transporter permease [KO:K05846]
L483_04395  glycine/betaine ABC transporter ATP-binding protein [KO:K05847] [EC:7.6.2.9]
L483_04940  spermidine/putrescine ABC transporter ATP-binding protein [KO:K10112] [EC:7.5.2.-]
L483_04680  toluene tolerance protein [KO:K07323]
L483_20845  organic solvent ABC transporter substrate-binding protein [KO:K02067]
L483_00350  ABC transporter permease [KO:K02067]
L483_04675  organic solvent ABC transporter substrate-binding protein [KO:K02067]
L483_20835  ABC transporter permease [KO:K02066]
L483_00360  ABC transporter permease [KO:K02066]
L483_04670  ABC transporter permease [KO:K02066]
L483_04685  anti-sigma factor antagonist [KO:K07122]
L483_20840  organic solvent ABC transporter ATP-binding protein [KO:K02065]
L483_00355  cell division protein FtsE [KO:K02065]
L483_04665  organic solvent ABC transporter ATP-binding protein [KO:K02065]
L483_04925  sugar ABC transporter substrate-binding protein [KO:K17315]
L483_04930  sugar ABC transporter permease [KO:K17316]
L483_04935  sugar ABC transporter permease [KO:K17317]
L483_21240  LacI family transcriptional regulator [KO:K10439]
L483_21230  ABC transporter permease [KO:K10440]
L483_21235  ribose ABC transporter ATPase [KO:K10441] [EC:7.5.2.7]
L483_21215  D-ribose pyranase [KO:K06726] [EC:5.4.99.62]
L483_31780  phosphate-binding protein [KO:K02040]
L483_10740  phosphate ABC transporter substrate-binding protein [KO:K02040]
L483_19920  membrane protein [KO:K02040]
L483_31775  phosphate ABC transporter permease [KO:K02037]
L483_10745  phosphate ABC transporter permease [KO:K02037]
L483_31770  phosphate ABC transporter permease [KO:K02038]
L483_10750  phosphate ABC transporter permease [KO:K02038]
L483_31765  pstB; phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
L483_10755  phosphate ABC transporter ATP-binding protein [KO:K02036] [EC:7.3.2.1]
L483_04170  phosphonate ABC transporter substrate-binding protein [KO:K02044]
L483_10440  phosphonate ABC transporter substrate-binding protein [KO:K02044]
L483_04180  ABC transporter permease [KO:K02042]
L483_04185  phosphonate ABC transporter permease [KO:K02042]
L483_10430  phosphonate ABC transporter permease [KO:K02042]
L483_04175  phosphonate ABC transporter [KO:K02041] [EC:7.3.2.2]
L483_10435  artP; arginine ABC transporter ATP-binding protein [KO:K02041] [EC:7.3.2.2]
L483_26110  ABC transporter [KO:K10001]
L483_26120  glutamate/aspartate transporter permease GltK [KO:K10002]
L483_26115  amino acid ABC transporter permease [KO:K10003]
L483_26125  amino acid ABC transporter ATPase [KO:K10004] [EC:7.4.2.1]
L483_27185  amino acid ABC transporter substrate-binding protein [KO:K09969]
L483_27180  amino acid ABC transporter permease [KO:K09970]
L483_27175  amino acid ABC transporter permease [KO:K09971]
L483_27170  methionine ABC transporter ATP-binding protein [KO:K09972] [EC:7.4.2.1]
L483_00870  cystine transporter subunit [KO:K02424]
L483_30920  ABC transporter substrate-binding protein [KO:K02424]
L483_00865  amino acid ABC transporter permease [KO:K10009]
L483_00860  amino acid ABC transporter ATP-binding protein [KO:K10010] [EC:7.4.2.1]
L483_24505  ABC transporter substrate-binding protein [KO:K10022]
L483_24495  ABC transporter permease [KO:K10023]
L483_24500  histidine/lysine/arginine/ornithine ABC transporter permease HisQ [KO:K10024]
L483_24490  histidine ABC transporter ATP-binding protein [KO:K10025] [EC:7.4.2.1]
L483_01420  amino acid ABC transporter [KO:K23055]
L483_01415  histidine/lysine/arginine/ornithine ABC transporter permease HisQ [KO:K23056]
L483_01410  ABC transporter permease [KO:K23057]
L483_01425  ATP-binding protein [KO:K23058] [EC:7.4.2.1]
L483_25740  amino acid ABC transporter substrate-binding protein [KO:K01999]
L483_29480  ABC transporter [KO:K01999]
L483_14520  amino acid-binding protein [KO:K01999]
L483_19495  amino acid ABC transporter substrate-binding protein [KO:K01999]
L483_25745  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
L483_29475  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
L483_14515  branched-chain amino acid ABC transporter permease [KO:K01997]
L483_19490  branched-chain amino acid transporter permease subunit LivH [KO:K01997]
L483_14510  branched-chain amino acid ABC transporter ATP-binding protein [KO:K01995 K01998]
L483_29470  branched-chain amino acid ABC transporter permease [KO:K01998]
L483_25750  livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998]
L483_19485  livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998]
L483_25755  livG; amino acid ABC transporter ATP-binding protein [KO:K01995]
L483_29465  livG; amino acid ABC transporter ATP-binding protein [KO:K01995]
L483_19480  ABC transporter [KO:K01995]
L483_29460  amino acid ABC transporter ATPase [KO:K01996]
L483_25760  amino acid ABC transporter ATPase [KO:K01996]
L483_14505  amino acid ABC transporter ATPase [KO:K01996]
L483_19475  amino acid ABC transporter ATPase [KO:K01996]
L483_30980  methionine ABC transporter substrate-binding protein [KO:K02073]
L483_00200  methionine ABC transporter substrate-binding protein [KO:K02073]
L483_00840  methionine ABC transporter substrate-binding protein [KO:K02073]
L483_00205  metal ABC transporter permease [KO:K02072]
L483_00830  metal ABC transporter permease [KO:K02072]
L483_00210  methionine ABC transporter ATP-binding protein [KO:K02071]
L483_00835  methionine ABC transporter ATP-binding protein [KO:K02071]
L483_29355  branched-chain amino acid ABC transporter substrate-binding protein [KO:K11959]
L483_29360  urea ABC transporter permease [KO:K11960]
L483_29365  amino acid ABC transporter permease [KO:K11961]
L483_29370  urea ABC transporter ATP-binding protein [KO:K11962]
L483_29375  urea ABC transporter ATP-binding protein [KO:K11963]
L483_04470  peptide ABC transporter substrate-binding protein [KO:K12368]
L483_04480  ABC transporter [KO:K12368]
L483_04485  ABC transporter [KO:K12368]
L483_31570  peptide ABC transporter substrate-binding protein [KO:K12368]
L483_04465  peptide ABC transporter permease [KO:K12369]
L483_04460  peptide ABC transporter [KO:K12370]
L483_04455  dppD; peptide ABC transporter ATP-binding protein [KO:K12371]
L483_04450  dppF; peptide ABC transporter ATP-binding protein [KO:K12372]
L483_18010  ABC transporter substrate-binding protein [KO:K13893]
L483_23080  hypothetical protein [KO:K13893]
L483_23085  hypothetical protein [KO:K13893]
L483_18015  microcin C ABC transporter permease YejB [KO:K13894]
L483_23090  microcin C ABC transporter permease YejB [KO:K13894]
L483_18020  ABC transporter permease [KO:K13895]
L483_23095  ABC transporter permease [KO:K13895]
L483_23100  microcin C ABC transporter ATP-binding protein YejF [KO:K13896]
L483_02755  iron-hydroxamate ABC transporter substrate-binding protein [KO:K06858]
L483_00240  ABC transporter substrate-binding protein [KO:K09815]
L483_19815  ABC transporter substrate-binding protein [KO:K09815]
L483_00225  znuB; zinc transporter [KO:K09816]
L483_19825  zinc ABC transporter permease [KO:K09816]
L483_00230  znuC; zinc transporter [KO:K09817] [EC:7.2.2.20]
L483_19820  manganese ABC transporter ATP-binding protein [KO:K09817] [EC:7.2.2.20]
L483_06415  Wzm [KO:K09690]
L483_06420  sugar ABC transporter ATP-binding protein [KO:K09691] [EC:7.5.2.14]
L483_08015  multidrug ABC transporter substrate-binding protein [KO:K09808]
L483_08025  multidrug ABC transporter substrate-binding protein [KO:K09808]
L483_08020  ABC transporter [KO:K09810] [EC:7.6.2.-]
L483_23935  hemagglutination activity protein [KO:K02196]
L483_23940  heme ABC transporter permease [KO:K02195]
L483_23945  Heme exporter protein B [KO:K02194]
L483_23950  cytochrome C biogenesis protein CcmA [KO:K02193] [EC:7.6.2.5]
L483_04780  permease [KO:K07091]
L483_04785  permease [KO:K11720]
L483_04640  lipopolysaccharide ABC transporter ATP-binding protein [KO:K06861] [EC:7.5.2.5]
L483_30690  cell division protein FtsX [KO:K09811]
L483_30695  cell division protein FtsE [KO:K09812]
L483_29810  ATP-binding protein [KO:K11085] [EC:7.5.2.6]
L483_24800  multidrug ABC transporter ATP-binding protein [KO:K18893]
L483_10565  multidrug ABC transporter ATP-binding protein [KO:K18893]
L483_04065  ATP-binding protein [KO:K12541]
L483_00510  ABC transporter [KO:K12541]
L483_06535  peptidase [KO:K12536]
L483_20675  peptidase [KO:K12536]
L483_23395  macrolide ABC transporter ATP-binding protein [KO:K05685] [EC:7.6.2.-]
L483_23430  cyclic peptide transporter [KO:K06160]
L483_09015  multidrug ABC transporter ATP-binding protein [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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