Entry Name ABC transporters - Pseudomonas aeruginosa B136-33
Description The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class Environmental Information Processing; Membrane transportBRITE hierarchy
Pathway map Ortholog table Other DBs Organism Pseudomonas aeruginosa B136-33 [GN:
psg ]
Gene G655_07490 ABC-type transporter periplasmic sulfonate-binding protein [KO:K15553 ]
G655_15825 molybdenum ABC transporter periplasmic molybdate-binding protein [KO:K02020 ]
G655_24725 binding-protein-dependent transport system inner membrane protein [KO:K02011 ]
G655_12040 putative periplasmic spermidine/putrescine-binding protein [KO:K11073 ]
G655_28290 glycine betaine/L-proline ABC transporter, periplasmic component [KO:K02002 ]
G655_28340 glycine betaine/L-proline ABC transporter, periplasmic substrate-binding protein [KO:K02002 ]
G655_08910 putative ATP-binding component of ABC transporter [KO:K10112 ] [EC:7.5.2.-]
G655_13360 putative binding protein component of ABC maltose/mannitol transporter [KO:K10227 ]
G655_13355 binding-protein-dependent maltose/mannitol transport protein [KO:K10228 ]
G655_13350 binding-protein-dependent maltose/mannitol transport protein [KO:K10229 ]
G655_08895 putative binding protein component of ABC sugar transporter [KO:K17315 ]
G655_08195 phosphonate ABC transporter periplasmic phosphonate-binding protein [KO:K02044 ]
G655_10180 histidine/lysine/arginine/ornithine ABC transporter permease HisM [KO:K10015 ]
G655_19910 leucine ABC transporter subunit substrate-binding protein LivK [KO:K01999 ]
G655_19920 livM; leucine/isoleucine/valine transporter permease subunit [KO:K01998 ]
G655_19925 livG; leucine/isoleucine/valine transporter ATP-binding subunit [KO:K01995 ]
G655_27985 putative binding protein component of ABC dipeptide transporter [KO:K12368 ]
G655_03905 iron-enterobactin transporter periplasmic binding protein [KO:K23185 ]
G655_09850 LolC/E family lipoprotein releasing system, transmembrane protein [KO:K09808 ]
G655_09855 lolD; lipoprotein transporter ATP-binding subunit [KO:K09810 ] [EC:7.6.2.-]
G655_13095 macrolide transporter ATP-binding/permease protein [KO:K05685 ] [EC:7.6.2.-]
Compound C00093 sn-Glycerol 3-phosphate
C01153 Orthophosphoric monoester
C01181 4-Trimethylammoniobutanoate
C01279 4-Amino-5-hydroxymethyl-2-methylpyrimidine
C03557 2-Aminoethylphosphonate
C03611 Galactose oligosaccharide
C03619 Methyl beta-D-galactoside
C04114 (E)-4-(Trimethylammonio)but-2-enoate
C06705 Capsular polysaccharide
C19872 N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570 alpha-1,5-L-Arabinobiose
C20571 alpha-1,5-L-Arabinotriose
C20572 alpha-1,5-L-Arabinotetraose
Reference Authors Tomii K, Kanehisa M.
Title A comparative analysis of ABC transporters in complete microbial genomes.
Journal Reference Authors Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
Title Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
Title Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
Journal Reference Authors Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
Title Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
Journal Reference Authors Quintero MJ, Montesinos ML, Herrero A, Flores E
Title Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
Journal Reference Authors Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
Title ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
Journal Reference Authors Valladares A, Montesinos ML, Herrero A, Flores E.
Title An ABC-type, high-affinity urea permease identified in cyanobacteria.
Journal Reference Authors Richard-Fogal CL, Frawley ER, Kranz RG
Title Topology and function of CcmD in cytochrome c maturation.
Journal Reference Authors Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
Title The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
Journal Reference Authors Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
Title The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
Journal Reference Authors Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
Title Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
Journal Reference Authors Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
Title MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
Journal KO pathway LinkDB All DBs
