KEGG   PATHWAY: ptrc04146
Entry
ptrc04146                   Pathway                                
Name
Peroxisome - Puccinia triticina (wheat leaf rust)
Description
Peroxisomes are essential organelles that play a key role in redox signalling and lipid homeostasis. They contribute to many crucial metabolic processes such as fatty acid oxidation, biosynthesis of ether lipids and free radical detoxification. The biogenesis of peroxisomes starts with the early peroxins PEX3, PEX16 and PEX19 and proceeds via several steps. The import of membrane proteins into peroxisomes needs PEX19 for recognition, targeting and insertion via docking at PEX3. Matrix proteins in the cytosol are recognized by peroxisomal targeting signals (PTS) and transported to the docking complex at the peroxisomal membrane. Peroxisomes' deficiencies lead to severe and often fatal inherited peroxisomal disorders (PD). PDs are usually classified in two groups. The first group is disorders of peroxisome biogenesis which include Zellweger syndrome, and the second group is single peroxisomal enzyme deficiencies.
Class
Cellular Processes; Transport and catabolism
Pathway map
ptrc04146  Peroxisome
ptrc04146

Other DBs
GO: 0005777
Organism
Puccinia triticina (wheat leaf rust) [GN:ptrc]
Gene
PtA15_4A683  uncharacterized protein [KO:K13335]
PtA15_1A563  uncharacterized protein [KO:K13337]
PtA15_1A1021  uncharacterized protein [KO:K13337]
PtA15_5A152  uncharacterized protein [KO:K13338]
PtA15_11A656  uncharacterized protein [KO:K13339]
PtA15_2A770  uncharacterized protein [KO:K13341]
PtA15_12A410  uncharacterized protein [KO:K13342]
PtA15_1A222  uncharacterized protein [KO:K13342]
PtA15_11A14  uncharacterized protein [KO:K13343]
PtA15_1A49  uncharacterized protein [KO:K13344]
PtA15_8A285  uncharacterized protein [KO:K13345]
PtA15_1A560  uncharacterized protein [KO:K13346]
PtA15_1A1018  uncharacterized protein [KO:K13346]
PtA15_16A391  uncharacterized protein [KO:K06664]
PtA15_2A867  uncharacterized protein [KO:K13348]
PtA15_5A132  uncharacterized protein [KO:K13348]
PtA15_6A114  uncharacterized protein [KO:K13348]
PtA15_1A786  uncharacterized protein [KO:K13348]
PtA15_8A69  uncharacterized protein [KO:K13350]
PtA15_8A70  uncharacterized protein [KO:K13350]
PtA15_3A374  uncharacterized protein [KO:K13352]
PtA15_4A29  uncharacterized protein [KO:K13354]
PtA15_5A180  uncharacterized protein [KO:K13354]
PtA15_8A272  uncharacterized protein [KO:K00232] [EC:1.3.3.6]
PtA15_1A532  uncharacterized protein [KO:K00232] [EC:1.3.3.6]
PtA15_8A701  uncharacterized protein [KO:K07513] [EC:2.3.1.16]
PtA15_16A251  uncharacterized protein [KO:K07513] [EC:2.3.1.16]
PtA15_6A358  uncharacterized protein [KO:K13237] [EC:1.3.1.124]
PtA15_7A133  uncharacterized protein [KO:K12663] [EC:5.3.3.21]
PtA15_13A466  uncharacterized protein [KO:K15628] [EC:7.6.2.4]
PtA15_16A272  uncharacterized protein [KO:K15628] [EC:7.6.2.4]
PtA15_6A744  uncharacterized protein [KO:K01897] [EC:6.2.1.3]
PtA15_7A228  uncharacterized protein [KO:K01897] [EC:6.2.1.3]
PtA15_1A664  uncharacterized protein [KO:K01897] [EC:6.2.1.3]
PtA15_3A636  uncharacterized protein [KO:K03426] [EC:3.6.1.22]
PtA15_5A489  uncharacterized protein [KO:K13355] [EC:3.6.1.77]
PtA15_5A334  uncharacterized protein [KO:K00624] [EC:2.3.1.7]
PtA15_5A335  uncharacterized protein [KO:K00624] [EC:2.3.1.7]
PtA15_11A62  uncharacterized protein [KO:K00624] [EC:2.3.1.7]
PtA15_1A464  uncharacterized protein [KO:K00624] [EC:2.3.1.7]
PtA15_10A381  uncharacterized protein [KO:K00830] [EC:2.6.1.44 2.6.1.45 2.6.1.51]
PtA15_10A568  uncharacterized protein [KO:K00273] [EC:1.4.3.3]
PtA15_6A287  uncharacterized protein [KO:K00031] [EC:1.1.1.42]
PtA15_12A491  uncharacterized protein [KO:K00306] [EC:1.5.3.1 1.5.3.7]
PtA15_5A917  uncharacterized protein [KO:K01640] [EC:4.1.3.4]
PtA15_8A550  uncharacterized protein [KO:K03781] [EC:1.11.1.6]
PtA15_11A310  uncharacterized protein [KO:K03781] [EC:1.11.1.6]
PtA15_11A322  uncharacterized protein [KO:K03781] [EC:1.11.1.6]
PtA15_3A652  uncharacterized protein [KO:K04565] [EC:1.15.1.1]
PtA15_3A857  uncharacterized protein [KO:K04565] [EC:1.15.1.1]
PtA15_11A666  uncharacterized protein [KO:K04564] [EC:1.15.1.1]
PtA15_18A34  uncharacterized protein [KO:K04564] [EC:1.15.1.1]
Reference
PMID:17055078
  Authors
Wanders RJ, Waterham HR
  Title
Peroxisomal disorders: the single peroxisomal enzyme deficiencies.
  Journal
Biochim Biophys Acta 1763:1707-20 (2006)
DOI:10.1016/j.bbamcr.2006.08.010
Reference
PMID:17055079
  Authors
Steinberg SJ, Dodt G, Raymond GV, Braverman NE, Moser AB, Moser HW
  Title
Peroxisome biogenesis disorders.
  Journal
Biochim Biophys Acta 1763:1733-48 (2006)
DOI:10.1016/j.bbamcr.2006.09.010
Reference
PMID:17010456
  Authors
Rottensteiner H, Theodoulou FL
  Title
The ins and outs of peroxisomes: co-ordination of membrane transport and peroxisomal metabolism.
  Journal
Biochim Biophys Acta 1763:1527-40 (2006)
DOI:10.1016/j.bbamcr.2006.08.012
Reference
PMID:16631601
  Authors
Iida R, Yasuda T, Tsubota E, Takatsuka H, Matsuki T, Kishi K
  Title
Human Mpv17-like protein is localized in peroxisomes and regulates expression of antioxidant enzymes.
  Journal
Biochem Biophys Res Commun 344:948-54 (2006)
DOI:10.1016/j.bbrc.2006.04.008
Related
pathway
ptrc00071  Fatty acid degradation
ptrc00230  Purine metabolism
ptrc00564  Glycerophospholipid metabolism
ptrc00565  Ether lipid metabolism
ptrc00900  Terpenoid backbone biosynthesis
KO pathway
ko04146   
LinkDB

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