KEGG   PATHWAY: rn00981
Entry
rn00981                     Pathway                                
Name
Insect hormone biosynthesis
Class
Metabolism; Metabolism of terpenoids and polyketides
Pathway map
rn00981  Insect hormone biosynthesis
rn00981

Module
M01013  Molting hormone biosynthesis, insects, 2,22,25-trideoxyecdysone => ecdysone => 20-hydroxyecdysone [PATH:rn00981]
M01047  Juvenile hormone biosynthesis, insects, farnesyl-PP => juvenile hormone III [PATH:rn00981]
Other DBs
GO: 0006718 0006697
Reaction
R02373  ecdysone:oxygen 3-oxidoreductase
R02374  ecdysone,hydrogen-donor:oxygen oxidoreductase (20-hydroxylating)
R03264  2-trans,6-trans-farnesol:NADP+ 1-oxidoreductase
R08132  
R08133  
R08134  2,22-dideoxyecdysone,reduced adrenodoxin:oxygen oxidoreductase (22-hydroxylating)
R08135  
R08136  
R08137  
R08138  3-dehydro-2,22-dideoxyecdysone,reduced adrenodoxin:oxygen oxidoreductase (22-hydroxylating)
R08139  
R08140  
R08141  
R08142  
R08143  
R08144  farnesyl-diphosphate phosphohydrolase
R08146  farnesal:NAD+ oxidoreductase
R08147  S-adenosyl-L-methionine:(2E,6E)-farnesoate O-methyltransferase
R08148  methyl (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
R08149  juvenile hormone III acylhydrolase
R08150  
R08151  S-adenosyl-L-methionine:juvenile hormone III acid O-methyltransferase
R08152  
R08153  
R08154  
R08155  
R10925  (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
R11007  cholesterol,NADH:oxygen oxidoreductase (7,8 dehydrogenating)
R11008  cholesterol,NADPH:oxygen oxidoreductase (7,8 dehydrogenating)
R11381  (2E,6E)-farnesol:oxygen oxidoreductase
Compound
C00187  Cholesterol
C00448  trans,trans-Farnesyl diphosphate
C00477  Ecdysone
C01126  (2E,6E)-Farnesol
C01164  7-Dehydrocholesterol
C02513  3-Dehydroecdysone
C02633  20-Hydroxyecdysone
C03461  2-trans,6-trans-Farnesal
C09694  Juvenile hormone III
C16493  2,22,25-Trideoxyecdysone
C16494  2,22-Dideoxyecdysone
C16495  2-Deoxyecdysone
C16496  3-Epiecdysone
C16497  3-Dehydro-2-deoxyecdysone
C16498  2,22-Dideoxy-3-dehydroecdysone
C16499  26-Hydroxyecdysone
C16500  20,26-Dihydroxyecdysone
C16502  Farnesoic acid
C16503  Methyl farnesoate
C16504  Juvenile hormone III acid
C16505  (10S)-Juvenile hormone III diol
C16506  (10S)-Juvenile hormone III acid diol
C16507  (10S)-Juvenile hormone III diol phosphate
C16508  12-trans-Hydroxy juvenile hormone III
C16509  14alpha-Hydroxy-5beta-cholest-7-ene-3,6-dione
Reference
PMID:15355237
  Authors
Belles X, Martin D, Piulachs MD.
  Title
The mevalonate pathway and the synthesis of juvenile hormone in insects.
  Journal
Annu Rev Entomol 50:181-99 (2005)
DOI:10.1146/annurev.ento.50.071803.130356
Reference
PMID:15026169
  Authors
Gilbert LI.
  Title
Halloween genes encode P450 enzymes that mediate steroid hormone biosynthesis in Drosophila melanogaster.
  Journal
Mol Cell Endocrinol 215:1-10 (2004)
DOI:10.1016/j.mce.2003.11.003
Reference
PMID:15350618
  Authors
Warren JT, Petryk A, Marques G, Parvy JP, Shinoda T, Itoyama K, Kobayashi J, Jarcho M, Li Y, O'Connor MB, Dauphin-Villemant C, Gilbert LI.
  Title
Phantom encodes the 25-hydroxylase of Drosophila melanogaster and Bombyx mori: a P450 enzyme critical in ecdysone biosynthesis.
  Journal
Insect Biochem Mol Biol 34:991-1010 (2004)
DOI:10.1016/j.ibmb.2004.06.009
Reference
  Authors
Omura T, Ishimura Y, Fujii Y (eds).
  Title
[Molecular Biology of P450] (In Japanese)
  Journal
Kodansya (2003)
Related
pathway
rn00900  Terpenoid backbone biosynthesis
KO pathway
ko00981   

DBGET integrated database retrieval system