KEGG   PATHWAY: rru02010
Entry
rru02010                    Pathway                                
Name
ABC transporters - Rhodospirillum rubrum ATCC 11170
Description
The ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of a wide variety of substrates such as ions, sugars, lipids, sterols, peptides, proteins, and drugs. The structure of a prokaryotic ABC transporter usually consists of three components; typically two integral membrane proteins each having six transmembrane segments, two peripheral proteins that bind and hydrolyze ATP, and a periplasmic (or lipoprotein) substrate-binding protein. Many of the genes for the three components form operons as in fact observed in many bacterial and archaeal genomes. On the other hand, in a typical eukaryotic ABC transporter, the membrane spanning protein and the ATP-binding protein are fused, forming a multi-domain protein with the membrane-spanning domain (MSD) and the nucleotide-binding domain (NBD).
Class
Environmental Information Processing; Membrane transport
Pathway map
rru02010  ABC transporters
rru02010

Other DBs
GO: 0043190 0043191 0043192
TC: 3.A.1
Organism
Rhodospirillum rubrum ATCC 11170 [GN:rru]
Gene
Rru_A3400  Thiosulphate-binding protein [KO:K23163]
Rru_A2074  Thiosulphate-binding protein [KO:K23163]
Rru_A3401  sulfate ABC transporter, permease protein CysT [KO:K02046]
Rru_A3402  sulfate ABC transporter, permease protein CysW [KO:K02047]
Rru_A3403  Sulphate transport system permease protein 1 [KO:K02045] [EC:7.3.2.3]
Rru_A1642  putative sulfonate/nitrate transport system substrate-binding protein [KO:K15598]
Rru_A1643  Binding-protein-dependent transport systems inner membrane component [KO:K15599]
Rru_A1644  ABC transporter component [KO:K15600]
Rru_A0704  Molybdenum ABC transporter, periplasmic binding protein [KO:K02020]
Rru_A0703  Molybdate ABC transporter, permease protein [KO:K02018]
Rru_A0702  Molybdate ABC transporter, ATP-binding protein [KO:K02017] [EC:7.3.2.5]
Rru_A3199  extracellular solute-binding protein, family 1 [KO:K02012]
Rru_A0769  extracellular solute-binding protein, family 1 [KO:K02012]
Rru_A3200  Binding-protein-dependent transport systems inner membrane component [KO:K02011]
Rru_A0768  Binding-protein-dependent transport systems inner membrane component [KO:K02011]
Rru_A3201  ABC transporter component [KO:K02010] [EC:7.2.2.7]
Rru_A0767  ABC transporter component [KO:K02010] [EC:7.2.2.7]
Rru_A3015  Twin-arginine translocation pathway signal [KO:K11069]
Rru_A3012  Binding-protein-dependent transport systems inner membrane component [KO:K11070]
Rru_A3013  Binding-protein-dependent transport systems inner membrane component [KO:K11071]
Rru_A3014  ABC transporter component [KO:K11072] [EC:7.6.2.11]
Rru_A1018  extracellular solute-binding protein, family 1 [KO:K11073]
Rru_A1015  Binding-protein-dependent transport systems inner membrane component [KO:K11074]
Rru_A1016  Binding-protein-dependent transport systems inner membrane component [KO:K11075]
Rru_A1017  Spermidine/putrescine ABC transporter ATP-binding subunit [KO:K11076] [EC:7.6.2.16]
Rru_A2477  Substrate-binding region of ABC-type glycine betaine transport system [KO:K02002]
Rru_A2476  Binding-protein-dependent transport systems inner membrane component [KO:K02001]
Rru_A2475  Glycine betaine/L-proline transport ATP-binding subunit [KO:K02000] [EC:7.6.2.9]
Rru_A2385  Substrate-binding region of ABC-type glycine betaine transport system [KO:K05845]
Rru_A2382  Binding-protein-dependent transport systems inner membrane component [KO:K05846]
Rru_A2384  Binding-protein-dependent transport systems inner membrane component [KO:K05846]
Rru_A2383  ABC transporter component [KO:K05847] [EC:7.6.2.9]
Rru_A1260  ABC transporter component [KO:K10112] [EC:7.5.2.-]
Rru_A0095  ABC transporter component [KO:K10112] [EC:7.5.2.-]
Rru_A1528  Toluene tolerance [KO:K07323]
Rru_A0056  Toluene tolerance [KO:K07323]
Rru_A2438  Mammalian cell entry related [KO:K02067]
Rru_A2439  Mammalian cell entry related [KO:K02067]
Rru_A2910  Mammalian cell entry related [KO:K02067]
Rru_A2447  Mammalian cell entry related [KO:K02067]
Rru_A0408  Protein of unknown function DUF140 [KO:K02066]
Rru_A2445  Protein of unknown function DUF140 [KO:K02066]
Rru_A2908  Protein of unknown function DUF140 [KO:K02066]
Rru_A0407  ABC transporter component [KO:K02065]
Rru_A2446  ABC transporter component [KO:K02065]
Rru_A2909  ABC transporter component [KO:K02065]
Rru_A0989  Twin-arginine translocation pathway signal [KO:K07335]
Rru_A2784  Basic membrane lipoprotein [KO:K07335]
Rru_A1902  Basic membrane lipoprotein [KO:K07335]
Rru_A2786  inner-membrane translocator [KO:K23535]
Rru_A1904  inner-membrane translocator [KO:K23535]
Rru_A2787  inner-membrane translocator [KO:K23536]
Rru_A1903  inner-membrane translocator [KO:K23536]
Rru_A2785  ABC transporter component [KO:K23537]
Rru_A1905  ABC transporter component [KO:K23537]
Rru_A0092  extracellular solute-binding protein, family 1 [KO:K17315]
Rru_A0093  Binding-protein-dependent transport systems inner membrane component [KO:K17316]
Rru_A0094  Binding-protein-dependent transport systems inner membrane component [KO:K17317]
Rru_A1365  ribose ABC transporter, periplasmic binding protein [KO:K10439]
Rru_A1363  inner-membrane translocator [KO:K10440]
Rru_A1364  ABC transporter component [KO:K10441] [EC:7.5.2.7]
Rru_A0247  Periplasmic binding protein/LacI transcriptional regulator [KO:K17205]
Rru_A0248  inner-membrane translocator [KO:K17206]
Rru_A0249  ABC transporter component [KO:K17207]
Rru_A0598  phosphate ABC transporter, periplasmic binding protein [KO:K02040]
Rru_A2035  phosphate binding protein, putative [KO:K02040]
Rru_A0599  Phosphate ABC transporter, permease protein PstC [KO:K02037]
Rru_A0600  Phosphate transport system permease protein 2 [KO:K02038]
Rru_A0601  Phosphate transport system permease protein 1 [KO:K02036] [EC:7.3.2.1]
Rru_A2087  extracellular solute-binding protein, family 3 [KO:K10001]
Rru_A2089  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K10002]
Rru_A2088  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K10003]
Rru_A2090  ABC transporter component [KO:K10004] [EC:7.4.2.1]
Rru_A1004  Lysine-arginine-ornithine-binding periplasmic protein [KO:K09969]
Rru_A0779  extracellular solute-binding protein, family 3 [KO:K09969]
Rru_A0439  extracellular solute-binding protein, family 3 [KO:K09969]
Rru_A0780  Binding-protein-dependent transport systems inner membrane component [KO:K09970]
Rru_A1003  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K09970]
Rru_A1002  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K09971]
Rru_A0781  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K09971]
Rru_A1001  ABC transporter component [KO:K09972] [EC:7.4.2.1]
Rru_A2251  extracellular solute-binding protein, family 3 [KO:K23055]
Rru_A2252  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K23056]
Rru_A2253  Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine [KO:K23057]
Rru_A2250  ABC transporter component [KO:K23058] [EC:7.4.2.1]
Rru_A3303  amide-urea binding protein [KO:K01999]
Rru_A3417  Extracellular ligand-binding receptor [KO:K01999]
Rru_A3506  putative branched-chain amino acid transport system substrate-binding protein [KO:K01999]
Rru_A3728  Extracellular ligand-binding receptor [KO:K01999]
Rru_A1746  Extracellular ligand-binding receptor [KO:K01999]
Rru_A0563  Twin-arginine translocation pathway signal [KO:K01999]
Rru_A2873  Extracellular ligand-binding receptor [KO:K01999]
Rru_A2171  Extracellular ligand-binding receptor [KO:K01999]
Rru_A3306  inner-membrane translocator [KO:K01997]
Rru_A3416  inner-membrane translocator [KO:K01997]
Rru_A3508  inner-membrane translocator [KO:K01997]
Rru_A3726  inner-membrane translocator [KO:K01997]
Rru_A1751  inner-membrane translocator [KO:K01997]
Rru_A0584  inner-membrane translocator [KO:K01997 K01998]
Rru_A3529  inner-membrane translocator [KO:K01997]
Rru_A3307  inner-membrane translocator [KO:K01998]
Rru_A3415  inner-membrane translocator [KO:K01998]
Rru_A3507  inner-membrane translocator [KO:K01998]
Rru_A3727  inner-membrane translocator [KO:K01998]
Rru_A1750  inner-membrane translocator [KO:K01998]
Rru_A1749  ABC transporter component [KO:K01995]
Rru_A3304  ABC transporter component [KO:K01995]
Rru_A3414  ABC transporter component [KO:K01995]
Rru_A3510  ABC transporter component [KO:K01995]
Rru_A0585  ABC transporter component [KO:K01995]
Rru_A3724  ABC transporter component [KO:K01995]
Rru_A1748  ABC transporter component [KO:K01996]
Rru_A3305  ABC transporter component [KO:K01996]
Rru_A3413  ABC transporter component [KO:K01996]
Rru_A3664  ABC transporter component [KO:K01996]
Rru_A3505  ABC transporter component [KO:K01996]
Rru_A3725  ABC transporter component [KO:K01996]
Rru_A2417  Lipoprotein YaeC [KO:K02073]
Rru_A0778  Lipoprotein YaeC [KO:K02073]
Rru_A0791  NLPA lipoprotein [KO:K02073]
Rru_A2418  Binding-protein-dependent transport systems inner membrane component [KO:K02072]
Rru_A0789  Binding-protein-dependent transport systems inner membrane component [KO:K02072]
Rru_A0788  ABC transporter component [KO:K02071]
Rru_A2419  ABC transporter component [KO:K02071]
Rru_A0592  extracellular solute-binding protein, family 5 [KO:K15580]
Rru_A0591  Binding-protein-dependent transport systems inner membrane component [KO:K15581]
Rru_A0590  Binding-protein-dependent transport systems inner membrane component [KO:K15582]
Rru_A0589  Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like [KO:K15583]
Rru_A0588  Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like [KO:K10823]
Rru_A2356  extracellular solute-binding protein, family 5 [KO:K12368]
Rru_A2357  Binding-protein-dependent transport systems inner membrane component [KO:K12369]
Rru_A2358  Binding-protein-dependent transport systems inner membrane component [KO:K12370]
Rru_A2359  Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like [KO:K12371]
Rru_A2360  Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like [KO:K12372]
Rru_A2277  Nickel ABC transporter, periplasmic nickel-binding [KO:K15584]
Rru_A2276  Binding-protein-dependent transport systems inner membrane component [KO:K15585]
Rru_A2275  Binding-protein-dependent transport systems inner membrane component [KO:K15586]
Rru_A2274  ABC transporter component [KO:K15587] [EC:7.2.2.11]
Rru_A2273  ABC transporter component [KO:K10824] [EC:7.2.2.11]
Rru_A3166  extracellular solute-binding protein, family 5 [KO:K13893]
Rru_A3167  Binding-protein-dependent transport systems inner membrane component [KO:K13894]
Rru_A3168  Binding-protein-dependent transport systems inner membrane component [KO:K13895]
Rru_A3169  ABC transporter component [KO:K13896]
Rru_A2390  Twin-arginine translocation pathway signal [KO:K09815]
Rru_A2388  ABC-3 transporter component [KO:K09816]
Rru_A2389  ABC transporter component [KO:K09817] [EC:7.2.2.20]
Rru_A2895  Twin-arginine translocation pathway signal [KO:K11604]
Rru_A2893  ABC-3 transporter component [KO:K11605]
Rru_A2892  ABC-3 transporter component [KO:K11606]
Rru_A2894  ABC transporter component [KO:K11607]
Rru_A3500  Cobalamin (vitamin B12) biosynthesis CbiM protein [KO:K02007]
Rru_A2634  Cobalt transport protein [KO:K02008]
Rru_A2633  ABC transporter component [KO:K02006]
Rru_A3501  lipoprotein, putative [KO:K10094]
Rru_A3499  conserved hypothetical protein [KO:K16915]
Rru_A3386  BioY protein [KO:K03523]
Rru_A1333  BioY protein [KO:K03523]
Rru_A1332  Cobalt transport protein [KO:K16783]
Rru_A3687  Cobalt transport protein [KO:K16783]
Rru_A3688  ABC transporter component [KO:K16784] [EC:7.6.2.-]
Rru_A1331  ABC transporter component [KO:K16784] [EC:7.6.2.-]
Rru_B0027  ABC-2 [KO:K09690]
Rru_B0028  ABC transporter related [KO:K09691] [EC:7.5.2.14]
Rru_A1578  Lipoprotein releasing system, transmembrane protein, LolC/E family [KO:K09808]
Rru_A2749  Protein of unknown function DUF214 [KO:K09808]
Rru_A1579  ABC transporter component [KO:K09810] [EC:7.6.2.-]
Rru_A2748  ABC transporter component [KO:K09810] [EC:7.6.2.-]
Rru_A0037  Heme exporter protein D (CcmD) [KO:K02196]
Rru_A0038  Cytochrome c-type biogenesis protein CcmC [KO:K02195]
Rru_A0039  Cytochrome c-type biogenesis protein CcmB [KO:K02194]
Rru_A0040  Heme exporter protein CcmA [KO:K02193] [EC:7.6.2.5]
Rru_A2943  permease YjgP/YjgQ [KO:K07091]
Rru_A3075  permease YjgP/YjgQ [KO:K11720]
Rru_A0011  ABC transporter component [KO:K06861] [EC:7.5.2.5]
Rru_A3255  Protein of unknown function DUF214 [KO:K09811]
Rru_A3254  ABC transporter component [KO:K09812]
Rru_A0189  ABC transporter, transmembrane region [KO:K14698] [EC:7.-.-.-]
Rru_A0864  ABC transporter, transmembrane region [KO:K14698] [EC:7.-.-.-]
Rru_A2340  ABC transporter, transmembrane region [KO:K14698] [EC:7.-.-.-]
Rru_A0188  ABC transporter, transmembrane region [KO:K14699] [EC:7.-.-.-]
Rru_A0863  ABC transporter, transmembrane region [KO:K14699] [EC:7.-.-.-]
Rru_A2339  ABC transporter component [KO:K14699] [EC:7.-.-.-]
Rru_A3561  ABC transporter, transmembrane region [KO:K11085] [EC:7.5.2.6]
Rru_A2942  ABC transporter, transmembrane region [KO:K11085] [EC:7.5.2.6]
Rru_A1120  ABC transporter, transmembrane region [KO:K24821]
Rru_B0039  Type I secretion system ATPase, PrtD [KO:K12536]
Rru_A3236  conserved hypothetical protein [KO:K05685] [EC:7.6.2.-]
Rru_A1497  Cyclic peptide transporter [KO:K06160]
Rru_A3300  ABC transporter component [KO:K02471]
Compound
C00009  Orthophosphate
C00025  L-Glutamate
C00031  D-Glucose
C00032  Heme
C00034  Manganese
C00037  Glycine
C00038  Zinc cation
C00041  L-Alanine
C00047  L-Lysine
C00049  L-Aspartate
C00051  Glutathione
C00059  Sulfate
C00062  L-Arginine
C00064  L-Glutamine
C00065  L-Serine
C00070  Copper
C00077  L-Ornithine
C00079  L-Phenylalanine
C00086  Urea
C00088  Nitrite
C00089  Sucrose
C00093  sn-Glycerol 3-phosphate
C00095  D-Fructose
C00098  Oligopeptide
C00107  Dipeptide
C00114  Choline
C00116  Glycerol
C00120  Biotin
C00121  D-Ribose
C00123  L-Leucine
C00134  Putrescine
C00135  L-Histidine
C00137  myo-Inositol
C00140  N-Acetyl-D-glucosamine
C00148  L-Proline
C00151  L-Amino acid
C00159  D-Mannose
C00175  Cobalt ion
C00181  D-Xylose
C00183  L-Valine
C00185  Cellobiose
C00188  L-Threonine
C00208  Maltose
C00212  Adenosine
C00243  Lactose
C00244  Nitrate
C00245  Taurine
C00255  Riboflavin
C00259  L-Arabinose
C00288  HCO3-
C00291  Nickel
C00294  Inosine
C00299  Uridine
C00315  Spermidine
C00320  Thiosulfate
C00330  Deoxyguanosine
C00333  D-Galacturonate
C00338  Lipopolysaccharide
C00378  Thiamine
C00379  Xylitol
C00387  Guanosine
C00392  Mannitol
C00407  L-Isoleucine
C00430  5-Aminolevulinate
C00470  Pectate
C00475  Cytidine
C00487  Carnitine
C00491  L-Cystine
C00492  Raffinose
C00503  Erythritol
C00526  Deoxyuridine
C00559  Deoxyadenosine
C00719  Betaine
C00794  D-Sorbitol
C00855  D-Methionine
C00865  Phospholipid
C00881  Deoxycytidine
C00919  Choline sulfate
C00973  Cyclomaltodextrin
C01083  alpha,alpha-Trehalose
C01153  Orthophosphoric monoester
C01157  Hydroxyproline
C01177  Inositol 1-phosphate
C01181  4-Trimethylammoniobutanoate
C01279  4-Amino-5-hydroxymethyl-2-methylpyrimidine
C01330  Sodium cation
C01417  Cyanate
C01487  D-Allose
C01606  Phthalate
C01630  Xylobiose
C01667  Bacitracin
C01674  Chitobiose
C01682  Nopaline
C01684  D-Rhamnose
C01762  Xanthosine
C01834  Lipoprotein
C01835  Maltotriose
C01935  Maltodextrin
C01946  Oleandomycin
C02160  Isomaltotriose
C02273  Digalacturonate
C03557  2-Aminoethylphosphonate
C03611  Galactose oligosaccharide
C03619  Methyl beta-D-galactoside
C04114  (E)-4-(Trimethylammonio)but-2-enoate
C04137  Octopine
C05349  Ciprofloxacin
C05402  Melibiose
C05512  Deoxyinosine
C05776  Vitamin B12
C06227  Fe(III)hydroxamate
C06229  Fe(III)dicitrate
C06230  Fe-enterobactin
C06232  Molybdate
C06687  Norfloxacin
C06705  Capsular polysaccharide
C06706  Lipo-oligosaccharide
C06707  Teichoic acid
C06767  Hemine
C07662  Sparfloxacin
C07663  Moxifloxacin
C11612  Polymyxin B
C13768  Colistin sulfate
C14818  Fe2+
C14819  Fe3+
C15521  Alkanesulfonate
C15719  Coelichelin
C16421  AI-2
C16692  Mannopine
C19609  Nickel(2+)
C19872  N-Formyl-4-amino-5-aminomethyl-2-methylpyrimidine
C20570  alpha-1,5-L-Arabinobiose
C20571  alpha-1,5-L-Arabinotriose
C20572  alpha-1,5-L-Arabinotetraose
C20573  Aldotetraouronic acid
C20679  Tungstate
C21066  D-Galactofuranose
C22040  S-Methyl-L-cysteine
G00457  Maltotetraose
Reference
PMID:9799792
  Authors
Tomii K, Kanehisa M.
  Title
A comparative analysis of ABC transporters in complete microbial genomes.
  Journal
Genome Res 8:1048-59 (1998)
DOI:10.1101/gr.8.10.1048
Reference
  Authors
Sperandeo P, Lau FK, Carpentieri A, De Castro C, Molinaro A, Deho G, Silhavy TJ, Polissi A
  Title
Functional analysis of the protein machinery required for transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
J Bacteriol 190:4460-9 (2008)
DOI:10.1128/JB.00270-08
Reference
  Authors
Ruiz N, Gronenberg LS, Kahne D, Silhavy TJ
  Title
Identification of two inner-membrane proteins required for the transport of lipopolysaccharide to the outer membrane of Escherichia coli.
  Journal
Proc Natl Acad Sci U S A 105:5537-42 (2008)
DOI:10.1073/pnas.0801196105
Reference
  Authors
Omata T, Price GD, Badger MR, Okamura M, Gohta S, Ogawa T
  Title
Identification of an ATP-binding cassette transporter involved in bicarbonate uptake in the cyanobacterium Synechococcus sp. strain PCC 7942.
  Journal
Proc Natl Acad Sci U S A 96:13571-6 (1999)
DOI:10.1073/pnas.96.23.13571
Reference
  Authors
Quintero MJ, Montesinos ML, Herrero A, Flores E
  Title
Identification of genes encoding amino acid permeases by inactivation of selected ORFs from the Synechocystis genomic sequence.
  Journal
Genome Res 11:2034-40 (2001)
DOI:10.1101/gr.196301
Reference
  Authors
Picossi S, Montesinos ML, Pernil R, Lichtle C, Herrero A, Flores E
  Title
ABC-type neutral amino acid permease N-I is required for optimal diazotrophic growth and is repressed in the heterocysts of Anabaena sp. strain PCC 7120.
  Journal
Mol Microbiol 57:1582-92 (2005)
DOI:10.1111/j.1365-2958.2005.04791.x
Reference
  Authors
Valladares A, Montesinos ML, Herrero A, Flores E.
  Title
An ABC-type, high-affinity urea permease identified in cyanobacteria.
  Journal
Mol Microbiol 43:703-15 (2002)
DOI:10.1046/j.1365-2958.2002.02778.x
Reference
  Authors
Richard-Fogal CL, Frawley ER, Kranz RG
  Title
Topology and function of CcmD in cytochrome c maturation.
  Journal
J Bacteriol 190:3489-93 (2008)
DOI:10.1128/JB.00146-08
Reference
  Authors
Suzuki H, Koyanagi T, Izuka S, Onishi A, Kumagai H
  Title
The yliA, -B, -C, and -D genes of Escherichia coli K-12 encode a novel glutathione importer with an ATP-binding cassette.
  Journal
J Bacteriol 187:5861-7 (2005)
DOI:10.1128/JB.187.17.5861-5867.2005
Reference
  Authors
Novikova M, Metlitskaya A, Datsenko K, Kazakov T, Kazakov A, Wanner B, Severinov K
  Title
The Escherichia coli Yej transporter is required for the uptake of translation inhibitor microcin C.
  Journal
J Bacteriol 189:8361-5 (2007)
DOI:10.1128/JB.01028-07
Reference
  Authors
Tikhonova EB, Devroy VK, Lau SY, Zgurskaya HI
  Title
Reconstitution of the Escherichia coli macrolide transporter: the periplasmic membrane fusion protein MacA stimulates the ATPase activity of MacB.
  Journal
Mol Microbiol 63:895-910 (2007)
DOI:10.1111/j.1365-2958.2006.05549.x
Reference
  Authors
Yamanaka H, Kobayashi H, Takahashi E, Okamoto K
  Title
MacAB is involved in the secretion of Escherichia coli heat-stable enterotoxin II.
  Journal
J Bacteriol 190:7693-8 (2008)
DOI:10.1128/JB.00853-08
KO pathway
ko02010   
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